| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Burn, P A Crooks, F Heatley, B Costall, R J Naylor, V Nohri. Synthesis and dopaminergic properties of some exo- and endo-2-aminobenzonorbornenes designed as rigid analogue of dopamine. Journal of medicinal chemistry. vol 25. issue 4. 1982-06-21. PMID:7200145. |
compounds 11 h and 14d, their n-methyl (11i and 11j) and n,n-dimethyl (14i and 14j) derivatives, and compounds 11f and 11g were inactive as dopamine agonists when evaluated for dopaminergic activity by their ability to induce stereotyped behavior in mice after subcutaneous injection and by their ability to cause hyperactivity in rats after bilateral injection into the nucleus accumbens. |
1982-06-21 |
2023-08-12 |
mouse |
| R D Hesch, M Hüsch, R Ködding, B Höffken, T Meye. Treatment of dopamine-dependent shock with triiodothyronine. Endocrine research communications. vol 8. issue 4. 1982-06-21. PMID:7338211. |
the effects of dopamine are mediated by alpha-, beta- and dopaminergic receptors. |
1982-06-21 |
2023-08-12 |
Not clear |
| S Ruggieri, P Falaschi, M Baldassarre, R D'Urso, G De Giorgio, A Rocco, A Agnol. Prolactin response to acute administration of different L-dopa plus decarboxylase inhibitors in Parkinson's disease. Neuropsychobiology. vol 8. issue 2. 1982-06-14. PMID:7070643. |
the data gathered indicate that benserazide-induced hyperprolactinemia in parkinsonian patients could be due to a direct effect of the drug at the hypothalamic level and consequently to an inhibition of dopamine decarboxylation in the tuberoinfundibular dopaminergic system. |
1982-06-14 |
2023-08-12 |
rat |
| L György, Z Orr, M Dód. Influence of dopamine and dopaminergic agonists on relaxation of isolated rabbit ileum induced by sympathetic nerve stimulation. Acta physiologica Academiae Scientiarum Hungaricae. vol 58. issue 2. 1982-06-14. PMID:7340393. |
influence of dopamine and dopaminergic agonists on relaxation of isolated rabbit ileum induced by sympathetic nerve stimulation. |
1982-06-14 |
2023-08-12 |
rabbit |
| L György, Z Orr, M Dód. Influence of dopamine and dopaminergic agonists on relaxation of isolated rabbit ileum induced by sympathetic nerve stimulation. Acta physiologica Academiae Scientiarum Hungaricae. vol 58. issue 2. 1982-06-14. PMID:7340393. |
the inhibitory effect of noradrenaline, dopamine and four dopaminergic agonists on smooth muscle relaxation induced by nerve stimulation was compared in isolated rabbit ileum. |
1982-06-14 |
2023-08-12 |
rabbit |
| R B Rastogi, R L Singhal, Y D Lapierr. Comparative effects of short- and long-term treatment with neuroleptics on behavioural activity as well as dopamine turnover in striatum. General pharmacology. vol 13. issue 1. 1982-05-27. PMID:6120880. |
it is suggested that after repeated treatment, "chemical denervation" occurs as a result of chronic blockade of dopaminergic transmission in the striatum and that the proliferation of dopamine receptors (i.e. |
1982-05-27 |
2023-08-12 |
rat |
| P Worms, H Depoortere, A Durand, P L Morselli, K G Lloyd, G Bartholin. gamma-Aminobutyric acid (GABA) receptor stimulation. I. Neuropharmacological profiles of progabide (SL 76002) and SL 75102, with emphasis on their anticonvulsant spectra. The Journal of pharmacology and experimental therapeutics. vol 220. issue 3. 1982-05-27. PMID:6278129. |
anticonvulsant doses are antagonistic to dopamine receptor-mediated behaviors, whereas much lower doses seem to facilitate the effects of dopaminergic transmission. |
1982-05-27 |
2023-08-12 |
Not clear |
| W J Logan, S I Hari. Specific uptake of norepinephrine and dopamine by homogenates of rat cerebral cortex after locus ceruleus lesion. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 3. 1982-05-27. PMID:7062118. |
two and 8 weeks after locus ceruleus lesion, a dmi-insensitive, benztropine-sensitive dopamine uptake becomes apparent in ipsilateral cortical preparations, this may represent proliferation or increased function of dopaminergic cortical projections, compensating for noradrenergic denervation. |
1982-05-27 |
2023-08-12 |
rat |
| R King, J D Raese, J D Barcha. Catastrophe theory of dopaminergic transmission: a revised dopamine hypothesis of schizophrenia. Journal of theoretical biology. vol 92. issue 4. 1982-05-21. PMID:6278228. |
catastrophe theory of dopaminergic transmission: a revised dopamine hypothesis of schizophrenia. |
1982-05-21 |
2023-08-12 |
Not clear |
| A C Church, B S Bunney, N R Kriege. Neuronal localization of dopamine-sensitive adenylate cyclase within the rat olfactory tubercle. Brain research. vol 234. issue 2. 1982-05-21. PMID:6800567. |
examination of 6-oh dopamine-treated tissue by glyoxylic acid-induced histofluorescence established the loss of dopaminergic terminals.the marked decrease of dopamine-sensitive adenylate cyclase accompanying the selective loss of neurons (kainic acid treatment) but not accompanying the loss of dopaminergic terminals (6-oh dopamine treatment) suggests that this enzyme occurs in the neurons and not in the glia or in the dopaminergic terminals of this region. |
1982-05-21 |
2023-08-12 |
rat |
| J R Sowers, G Berg, V S Martin, D M Maye. Dopaminergic modulation of aldosterone secretion in the rhesus monkey: evidence that dopamine affects the late pathway of aldosterone biosynthesis by inhibiting the conversion of corticosterone to 18-hydroxycorticosterone. Endocrinology. vol 110. issue 4. 1982-05-21. PMID:7060520. |
dopaminergic modulation of aldosterone secretion in the rhesus monkey: evidence that dopamine affects the late pathway of aldosterone biosynthesis by inhibiting the conversion of corticosterone to 18-hydroxycorticosterone. |
1982-05-21 |
2023-08-12 |
monkey |
| I D Hirschhorn, M H Makman, N S Sharples. Dopamine receptor sensitivity following nigrostriatal lesion in the aged rat. Brain research. vol 234. issue 2. 1982-05-21. PMID:7199364. |
the denervated striata of young rats had greatly enhanced dopaminergic sensitivity as evidenced by apomorphine induced rotational behavior and increased dopamine stimulated adenylate cyclase activity and [3h]adtn binding. |
1982-05-21 |
2023-08-12 |
rat |
| I D Hirschhorn, M H Makman, N S Sharples. Dopamine receptor sensitivity following nigrostriatal lesion in the aged rat. Brain research. vol 234. issue 2. 1982-05-21. PMID:7199364. |
old rats responded similarly with a very high degree of increased dopaminergic sensitivity in both the behavioral and biochemical parameters, demonstrating that the ability to regulate dopamine receptors remains basically intact. |
1982-05-21 |
2023-08-12 |
rat |
| C Vadasz, H Baker, T H Joh, A Lajtha, D J Rei. The inheritance and genetic correlation of tyrosine hydroxylase activities in the substantia nigra and corpus striatum in the C x B recombinant inbred mouse strains. Brain research. vol 234. issue 1. 1982-05-12. PMID:6120745. |
in mouse, strain differences in the activity of tyrosine hydroxylase (th) in ventral midbrain dopamine systems of substantia nigra-a10 (sn) region of mouse brain and in a terminal field, the striatum (cs), can be entirely attributed to variations in the number of dopaminergic neurons2. |
1982-05-12 |
2023-08-12 |
mouse |
| J M Kaufman, A Elewaut, A Vermeule. Effect of domperidone on prolactin (PRL)and thyrotrophin (TSH) secretion. Archives internationales de pharmacodynamie et de therapie. vol 254. issue 2. 1982-05-12. PMID:6802092. |
the data of the present study suggest that dopamine blockade at pituitary (or median eminence) level is able to stimulate maximally the lactotrophs and emphasize the important role of the dopaminergic system in the interrelated regulation of tsh and prl secretion at the pituitary level. |
1982-05-12 |
2023-08-12 |
human |
| J M Rabey, Y Vardi, R Ravid, D Ayalo. Dissociation of thyrotropin and prolactin responsiveness to thyrotropin releasing hormone stimulation in L-dopa treated parkinsonian patients. Hormone research. vol 15. issue 2. 1982-04-20. PMID:6799381. |
the dissociation or response to trh under the same inhibitory action of dopaminergic stimulation can be interpreted as demonstrating a greater sensitivity of the pituitary thyrotrophs, than the prolactin secreting cells, to the blocking effect of dopamine. |
1982-04-20 |
2023-08-12 |
Not clear |
| N D Martensz, J Herber. Drug-induced hyperprolactinaemia and discharges of luteinizing hormone evoked by oestrogen in ovariectomized rhesus monkeys. The Journal of endocrinology. vol 92. issue 1. 1982-04-20. PMID:7057119. |
this hypothesis was tested in ovariectomized rhesus monkeys rendered hyperprolactinaemic by treatment with two dopamine antagonists, domperidone, a compound reported not to cross the blood-brain barrier in rats, and sulpiride, a drug with known actions on both pituitary and central dopaminergic receptors. |
1982-04-20 |
2023-08-12 |
rat |
| E Stafanini, Y Clement-Cormie. Detection of dopamine receptors in the area postrema. European journal of pharmacology. vol 74. issue 2-3. 1982-04-20. PMID:7327206. |
the displacement of the radioligand by different dopamine agonists and antagonists indicated that the labeled sites were dopaminergic in nature. |
1982-04-20 |
2023-08-12 |
dog |
| A E Snow, S M Tucker, W L Dewe. The role of neurotransmitters in stress-induced antinociception (SIA). Pharmacology, biochemistry, and behavior. vol 16. issue 1. 1982-04-12. PMID:6120525. |
when dopaminergic tone was increased with apomorphine (0.05 mg/kg, sc) the increase of tail-flick latency after stress was markedly attenuated whereas blockage of dopamine receptors with haloperidol (2.5 mg/kg, ip) increased the peak and duration of sia. |
1982-04-12 |
2023-08-12 |
Not clear |
| A Argiolas, G Mereu, G Serra, M R Melis, F Fadda, G L Gess. N-n-propyl-norapomorphine: an extremely potent stimulant of dopamine autoreceptors. Brain research. vol 231. issue 1. 1982-04-12. PMID:6799148. |
n-n-propyl-norapomorphine (npa) is 10-20 times more potent than apomorphine in producing hypomotility and inhibiting both striatal and limbic dopamine (da) synthesis and the firing rate of nigral dopaminergic cells in rats. |
1982-04-12 |
2023-08-12 |
rat |