| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S J List, K A Wreggett, P Seema. Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 7. 1982-09-17. PMID:6124583. |
in order to develop more selective methods for labeling brain dopamine receptors, this study describes in detail the properties of 2-amino-6,7,-[3h]dihydroxy-1,2,3,4,-tetrahydronaphthalene ([3h] adtn) binding to dopaminergic sites in rat, calf, and human brain. |
1982-09-17 |
2023-08-12 |
human |
| S J List, K A Wreggett, P Seema. Striatal binding of 2-amino-6,7-[3H]dihydroxy-1,2,3,4-tetrahydronaphthalene to two dopaminergic sites distinguished by their low and high affinity for neuroleptics. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 7. 1982-09-17. PMID:6124583. |
very low concentrations of dopamine and dopaminergic catecholamines (with ic50 values of 1 to 10 nm) inhibited the binding of [3h]adtn to both sites. |
1982-09-17 |
2023-08-12 |
human |
| A L Gundlach, D McDonald, P M Bear. [3H]Spiperone labels non-cyclase-linked dopamine receptors in the ventral tegmental area of rat brain. Journal of neurochemistry. vol 39. issue 3. 1982-09-17. PMID:7097294. |
specific binding was displaced by the dopaminergic agonists dopamine, apomorphine, and 2-amino-6,7-dihydroxytetralin, and stereospecifically by the neuroleptic drugs butaclamol and flupenthixol. |
1982-09-17 |
2023-08-12 |
rat |
| C Y Yim, G J Mogenso. Response of nucleus accumbens neurons to amygdala stimulation and its modification by dopamine. Brain research. vol 239. issue 2. 1982-09-10. PMID:6284305. |
the results suggest that the attenuation of the excitatory response to amygdala stimulation was due to the release of dopamine from mesolimbic dopaminergic neurons. |
1982-09-10 |
2023-08-12 |
rat |
| P C Jobe, H E Laird, K H Ko, T Ray, J W Daile. Abnormalities in monoamine levels in the central nervous system of the genetically epilepsy-prone rat. Epilepsia. vol 23. issue 4. 1982-09-10. PMID:6284498. |
the lack of abnormalities in brain dopamine concentrations strengthens our hypothesis that dopaminergic transmission does not regulate seizure susceptibility in this model. |
1982-09-10 |
2023-08-12 |
rat |
| A Sasak. [Effect of sulpiride on plasma TSH secretion in various hypothalamo-pituitary disorders (author's transl)]. Nihon Naibunpi Gakkai zasshi. vol 58. issue 3. 1982-09-10. PMID:7095211. |
to study the hypothalamic dopaminergic participation in tsh secretion in various hypothalamo-pituitary disorders, we examined the effect of sulpiride, a dopamine antagonist. |
1982-09-10 |
2023-08-12 |
human |
| J García de Y'ebenes, J J Gervas, J Iglesias, M A Mena, R Martín del Rio, E Somoz. Biochemical findings in a case of parkinsonism secondary to brain tumor. Annals of neurology. vol 11. issue 3. 1982-08-26. PMID:7092184. |
the findings suggest that parkinsonism was caused by the brain tumor, which damaged both the presynaptic dopaminergic nigrostriatal neurons and the postsynaptic dopamine receptors. |
1982-08-26 |
2023-08-12 |
Not clear |
| C G Lauer, L M Braley, A I Menachery, G H William. Metoclopramide inhibits aldosterone biosynthesis in vitro. Endocrinology. vol 111. issue 1. 1982-08-14. PMID:6282568. |
thus, metoclopramide may be a partial dopaminergic agonist: in vitro where dopamine levels are negligible, it is an agonist, whereas in vivo where dopamine concentrations are greater, it is an antagonist. |
1982-08-14 |
2023-08-12 |
rat |
| M L Heiman, N Ben-Jonatha. Dopaminergic receptors in the rat anterior pituitary change during the estrous cycle. Endocrinology. vol 111. issue 1. 1982-08-14. PMID:7200868. |
since a complex relationship is apparent between alterations in dopaminergic receptor number and plasma prl levels, we postulate that these receptors may be regulated by dopamine, ovarian steroids, and/or prl itself. |
1982-08-14 |
2023-08-12 |
rat |
| M L Heiman, N Ben-Jonatha. Dopaminergic receptors in the rat anterior pituitary change during the estrous cycle. Endocrinology. vol 111. issue 1. 1982-08-14. PMID:7200868. |
such a change in the number of dopaminergic binding sites may e an important component in pituitary responsiveness to dopamine inhibition of prl secretion throughout the estrous cycle. |
1982-08-14 |
2023-08-12 |
rat |
| K Kikuchi, A Miyama, T Nakao, Y Takigami, A Kondo, T Mito, N Ura, M Tsuzuki, O Iimur. Hemodynamic and natriuretic responses to intravenous infusion of dopamine in patients with essential hypertension. Japanese circulation journal. vol 46. issue 5. 1982-07-19. PMID:7043016. |
the changes in unav positively correlated with delta fena and delta fep in both low renin (group l) and normal renin eht (group n) and with delta ccr i group n but not in group l. the mean values of delta fena, delta fep and delta fek were significantly higher in group l as compared with those in age-matched group n. these results suggest that, since the enhanced response to infused dopamine may reflect reduced dopaminergic activity, attenuation of renal dopaminergic activity might exist and be involved through a distribution of water-sodium metabolism, at least in part, in the pathophysiological mechanism in eht, particularly in group l. |
1982-07-19 |
2023-08-12 |
human |
| M W Hamblin, I Crees. 3H-dopamine binding to rat striatal D-2 and D-3 sites: enhancement by magnesium and inhibition by guanine nucleotides and sodium. Life sciences. vol 30. issue 18. 1982-07-19. PMID:7078356. |
such studies have failed, however, to demonstrate high affinity 3h-dopamine binding to d-2 sites, which can be labeled by 3h-butyrophenones, and which represent the putative dopamine receptors most strongly implicated in the behavioral correlates of dopaminergic cns activity. |
1982-07-19 |
2023-08-12 |
rat |
| T Di Paolo, P J Bédard, A Dupont, P Poyet, F Labri. Effects of estradiol on intact and denervated striatal dopamine receptors and on dopamine levels: a biochemical and behavioral study. Canadian journal of physiology and pharmacology. vol 60. issue 3. 1982-07-19. PMID:7200388. |
the present study describes the effect of chronic estrogen treatment on striatal dopamine levels and dopamine receptors, as well as on apomorphine-induced circling, a behavioral model reflecting dopaminergic activity in the rat striatum. |
1982-07-19 |
2023-08-12 |
rat |
| B Berger, U Di Porzio, M C Daguet, M Gay, A Vigny, J Glowinski, A Prochiant. Long-term development of mesencephalic dopaminergic neurons of mouse embryos in dissociated primary cultures: morphological and histochemical characteristics. Neuroscience. vol 7. issue 1. 1982-07-08. PMID:6123092. |
four approaches were used to identify the dopaminergic neurons in vitro: fluorescence histochemistry of newly taken up exogenous norepinephrine, radioautography after labelling with (3h) dopamine, tyrosine hydroxylase-like immunoreactivity and fluorescence histochemistry of endogenous stores of catecholamines. |
1982-07-08 |
2023-08-12 |
mouse |
| S R Schif. Conditioned dopaminergic activity. Biological psychiatry. vol 17. issue 2. 1982-07-08. PMID:7200377. |
these studies examine the possibility that drugs (amphetamine and apomorphine) affecting dopamine metabolism might show conditioning properties and tests the hypothesis that dopaminergic activity might be responsible for any conditioning seen. |
1982-07-08 |
2023-08-12 |
Not clear |
| S R Schif. Conditioned dopaminergic activity. Biological psychiatry. vol 17. issue 2. 1982-07-08. PMID:7200377. |
if environmental cues can act as conditioning signals, affecting the activity of dopaminergic neurons, conditioning factors might contribute to fluctuations in the clinical status of individuals with neurologic or psychiatric conditions influenced by alterations in dopamine metabolism or receptor function. |
1982-07-08 |
2023-08-12 |
Not clear |
| J J Feigenbaum, J Yanai, R B Blass, B Moon, H Klawan. The effect of drugs altering striatal dopamine levels on apomorphine induced stereotypy. Pharmacology, biochemistry, and behavior. vol 16. issue 2. 1982-06-24. PMID:7200236. |
this finding was unexpected, as it has previously been maintained that drugs which exert any action on striatal da terminals exclusively would affect only indirect dopaminergic agonists, as opposed to apomorphine which induces stereotypy by acting directly on postsynaptic dopamine receptors. |
1982-06-24 |
2023-08-12 |
Not clear |
| K Murugaiah, A Theodorou, S Mann, A Clow, P Jenner, C D Marsde. Chronic continuous administration of neuroleptic drugs alters cerebral dopamine receptors and increases spontaneous dopaminergic action in the striatum. Nature. vol 296. issue 5857. 1982-06-21. PMID:6122161. |
chronic continuous administration of neuroleptic drugs alters cerebral dopamine receptors and increases spontaneous dopaminergic action in the striatum. |
1982-06-21 |
2023-08-12 |
Not clear |
| J H Growdon, E Melamed, M Logue, F Hefti, R J Wurtma. Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease. Life sciences. vol 30. issue 10. 1982-06-21. PMID:6175872. |
these data indicate that l-tyrosine administration can increase dopamine turnover in patients with disorders in which physicians wish to enhance dopaminergic neurotransmission. |
1982-06-21 |
2023-08-12 |
rat |
| P Burn, P A Crooks, F Heatley, B Costall, R J Naylor, V Nohri. Synthesis and dopaminergic properties of some exo- and endo-2-aminobenzonorbornenes designed as rigid analogue of dopamine. Journal of medicinal chemistry. vol 25. issue 4. 1982-06-21. PMID:7200145. |
synthesis and dopaminergic properties of some exo- and endo-2-aminobenzonorbornenes designed as rigid analogue of dopamine. |
1982-06-21 |
2023-08-12 |
mouse |