| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tobias Morville, Kristoffer H Madsen, Hartwig R Siebner, Oliver J Hulm. Reward signalling in brainstem nuclei under fluctuating blood glucose. PloS one. vol 16. issue 4. 2021-09-13. PMID:33826633. |
phasic dopamine release from mid-brain dopaminergic neurons is thought to signal errors of reward prediction (rpe). |
2021-09-13 |
2023-08-13 |
human |
| Oleg Kovtun, Ruben Torres, Riley S Ferguson, Travis Josephs, Sandra J Rosentha. Single Quantum Dot Tracking Unravels Agonist Effects on the Dopamine Receptor Dynamics. Biochemistry. vol 60. issue 13. 2021-09-10. PMID:32584548. |
d2 dopamine receptors (drd2s) belong to a family of g protein-coupled receptors that modulate synaptic dopaminergic tone via regulation of dopamine synthesis, storage, and synaptic release. |
2021-09-10 |
2023-08-13 |
Not clear |
| Amy Hauck Newman, Therese Ku, Chloe J Jordan, Alessandro Bonifazi, Zheng-Xiong X. New Drugs, Old Targets: Tweaking the Dopamine System to Treat Psychostimulant Use Disorders. Annual review of pharmacology and toxicology. vol 61. 2021-09-09. PMID:33411583. |
as both cocaine and methamphetamine rapidly increase dopamine (da) levels in mesolimbic brain regions, leading to euphoria that in some can lead to addiction, targets in which this increased dopaminergic tone may be mitigated have been explored. |
2021-09-09 |
2023-08-13 |
Not clear |
| Conner W Wallace, Nari S Beatty, Sarah A Hutcherson, Heather A Emmons, Madison C Loudermilt, Steve C Fordah. Replacing a Palatable High-Fat Diet with a Low-Fat Alternative Heightens κ-Opioid Receptor Control over Nucleus Accumbens Dopamine. Nutrients. vol 13. issue 7. 2021-09-08. PMID:34371851. |
diet-induced obesity reduces dopaminergic neurotransmission in the nucleus accumbens (nac), and stressful weight loss interventions could promote cravings for palatable foods high in fat and sugar that stimulate dopamine. |
2021-09-08 |
2023-08-13 |
mouse |
| Yang Feng, Tao Li, Changyang Xing, Chen Wang, Yunyou Duan, Lijun Yuan, Yajun Zhan. Effective inhibition of miR-330/SHIP1/NF-κB signaling pathway via miR-330 sponge repolarizes microglia differentiation. Cell biology international. vol 45. issue 4. 2021-09-06. PMID:33325083. |
in the lps-induced pd mice, administration of raav-sponge-gfp suppressed activation of microglia, downregulated proinflammatory cytokines, resumed the secretion of dopamine, rescued the dopaminergic neurons, and alleviated motor dysfunction. |
2021-09-06 |
2023-08-13 |
mouse |
| Abeer Dagra, Douglas R Miller, Min Lin, Adithya Gopinath, Fatemeh Shaerzadeh, Sharonda Harris, Zachary A Sorrentino, Jonatan Fullerton Støier, Sophia Velasco, Janelle Azar, Adetola R Alonge, Joseph J Lebowitz, Brittany Ulm, Mengfei Bu, Carissa A Hansen, Nikhil Urs, Benoit I Giasson, Habibeh Khoshboue. α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability. NPJ Parkinson's disease. vol 7. issue 1. 2021-09-04. PMID:34408150. |
we employed molecular biology, electrophysiology, and live-cell imaging to investigate how excessive α-synuclein expression alters multiple characteristics of dopaminergic neuronal dynamics and dopamine transmission in cultured dopamine neurons conditionally expressing gcamp6f. |
2021-09-04 |
2023-08-13 |
mouse |
| Abeer Dagra, Douglas R Miller, Min Lin, Adithya Gopinath, Fatemeh Shaerzadeh, Sharonda Harris, Zachary A Sorrentino, Jonatan Fullerton Støier, Sophia Velasco, Janelle Azar, Adetola R Alonge, Joseph J Lebowitz, Brittany Ulm, Mengfei Bu, Carissa A Hansen, Nikhil Urs, Benoit I Giasson, Habibeh Khoshboue. α-Synuclein-induced dysregulation of neuronal activity contributes to murine dopamine neuron vulnerability. NPJ Parkinson's disease. vol 7. issue 1. 2021-09-04. PMID:34408150. |
we found that overexpression of α-synuclein in mouse (male and female) dopaminergic neurons altered neuronal firing properties, calcium dynamics, dopamine release, protein expression, and morphology. |
2021-09-04 |
2023-08-13 |
mouse |
| Dana Mueller, Kameko Halfman. Dopamine, religiosity, and utilitarian moral judgment. Social neuroscience. 2021-09-03. PMID:34461025. |
we measured dopamine using spontaneous eyeblink rate, an indirect measure associated with striatal dopaminergic transmission. |
2021-09-03 |
2023-08-13 |
human |
| Dina M Monir, Motamed E Mahmoud, Omyma G Ahmed, Ibrahim F Rehan, Amany Abdelrahma. Forced exercise activates the NrF2 pathway in the striatum and ameliorates motor and behavioral manifestations of Parkinson's disease in rotenone-treated rats. Behavioral and brain functions : BBF. vol 16. issue 1. 2021-09-02. PMID:33158454. |
parkinson's disease (pd) is a common neurodegenerative disorder characterized by progressive loss of nigrostriatal dopaminergic neurons leading to dopamine depletion and problems of movement, emotions, and cognition. |
2021-09-02 |
2023-08-13 |
rat |
| Mustafa T Ardah, Greeshma Bharathan, Tohru Kitada, M Emdadul Haqu. Ellagic Acid Prevents Dopamine Neuron Degeneration from Oxidative Stress and Neuroinflammation in MPTP Model of Parkinson's Disease. Biomolecules. vol 10. issue 11. 2021-09-02. PMID:33172035. |
however, treatment with ea prior to mptp injection significantly rescued the dopaminergic neurons and dopamine transporter. |
2021-09-02 |
2023-08-13 |
Not clear |
| Débora Dreher Nabinger, Stefani Altenhofen, Júlia Vasconcellos Peixoto, Julia Maria Kuhl da Silva, Robert Gerlai, Carla Denise Bona. Feeding status alters exploratory and anxiety-like behaviors in zebrafish larvae exposed to quinpirole. Progress in neuro-psychopharmacology & biological psychiatry. vol 108. 2021-09-02. PMID:33212194. |
nutritional status can impact dopamine reuptake, receptor affinity, transporter activity, and the effects of drugs that bind to dopamine receptors or interact with dopaminergic system. |
2021-09-02 |
2023-08-13 |
human |
| Li Zou, Xingyu Zhang, Min Xiong, Lanxia Meng, Ye Tian, Lina Pan, Xin Yuan, Guiqin Chen, Zhihao Wang, Lihong Bu, Zhaohui Yao, Zhaohui Zhang, Keqiang Ye, Zhentao Zhan. Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease. Neurobiology of disease. vol 154. 2021-09-02. PMID:33677035. |
synaptic dysfunction impairs dopamine turnover and contributes to the degeneration of dopaminergic neurons. |
2021-09-02 |
2023-08-13 |
mouse |
| Gerly Tamm, Kairi Kreegipuu, Jaanus Harr. Platelet MAO activity and COMT Val158Met genotype interaction predicts visual working memory updating efficiency. Behavioural brain research. vol 407. 2021-09-02. PMID:33745984. |
the findings support the view that serotonin modulates dopaminergic activation in updating and contribute to understanding the role of serotonin in pfc, top-down inhibitory signals, and its interactions with dopamine in wm processes. |
2021-09-02 |
2023-08-13 |
human |
| Puneet K Sharma, Lisa Wells, Gaia Rizzo, Joanna L Elson, Jan Passchier, Eugenii A Rabiner, Roger N Gunn, David T Dexter, Ilse S Pienaa. DREADD Activation of Pedunculopontine Cholinergic Neurons Reverses Motor Deficits and Restores Striatal Dopamine Signaling in Parkinsonian Rats. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 17. issue 3. 2021-09-01. PMID:31965550. |
stimulation of excitatory designer receptors exclusively activated by designer drugs expressed within ppn cholinergic neurons activated residual nigrostriatal dopaminergic neurons to produce profound motor recovery, which correlated with striatal dopamine efflux as well as restored dopamine receptor 1- and dopamine receptor 2-based medium spiny neuron activity, as was ascertained with c-fos-based immunohistochemistry and stereological cell counts. |
2021-09-01 |
2023-08-13 |
rat |
| Yuhei Mori, Itaru Miura, Michinari Nozaki, Yusuke Osakabe, Ryuta Izumi, Takahiro Akama, So Kimura, Hirooki Yab. Electroconvulsive Therapy for Parkinson's Disease with Depression and Neuroleptic Malignant Syndrome: A Case Report. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 19. issue 3. 2021-09-01. PMID:34294629. |
because advanced parkinson's disease can sometimes be refractory to treatment based on pharmacological treatment-induced dopamine dysfunction, psychiatrists often have difficulty treating psychiatric symptoms; electroconvulsive therapy may stabilize the dopaminergic system in such cases, presenting a possible non-pharmacologic treatment option for parkinson's disease. |
2021-09-01 |
2023-08-13 |
Not clear |
| Linlin Zhang, Yanan Zheng, Junxia Xie, Limin Sh. Potassium channels and their emerging role in parkinson's disease. Brain research bulletin. vol 160. 2021-08-31. PMID:32305406. |
parkinson's disease (pd) is the second most common neurodegenerative disorder, which is associated with a selective loss of dopaminergic neurons in the substantia nigra (sn) and a reduction of dopamine in the striatum. |
2021-08-31 |
2023-08-13 |
Not clear |
| Valtteri Kaasinen, Tero Vahlberg, A Jon Stoessl, Antonio P Strafella, Angelo Antonin. Dopamine Receptors in Parkinson's Disease: A Meta-Analysis of Imaging Studies. Movement disorders : official journal of the Movement Disorder Society. vol 36. issue 8. 2021-08-31. PMID:33955044. |
in pd, compensatory changes in dopamine receptors emerge as a consequence of the loss of dopamine nerve terminals or dopaminergic pharmacotherapy. |
2021-08-31 |
2023-08-13 |
human |
| Bryant J Jongkee. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating. Cognitive, affective & behavioral neuroscience. vol 20. issue 3. 2021-08-30. PMID:32133585. |
these results are consistent with an inverted-u relationship between dopamine and wm, and they indicate that updating and gating are differentially affected by a dopaminergic manipulation. |
2021-08-30 |
2023-08-13 |
human |
| Rasem Mustafa, Chahinaz Rawas, Nadja Mannal, Grzegorz Kreiner, Björn Spittau, Katarzyna Kamińska, Rüstem Yilmaz, Christina Pötschke, Joachim Kirsch, Birgit Liss, Kerry L Tucker, Rosanna Parlat. Targeted Ablation of Primary Cilia in Differentiated Dopaminergic Neurons Reduces Striatal Dopamine and Responsiveness to Metabolic Stress. Antioxidants (Basel, Switzerland). vol 10. issue 8. 2021-08-30. PMID:34439532. |
targeted ablation of primary cilia in differentiated dopaminergic neurons reduces striatal dopamine and responsiveness to metabolic stress. |
2021-08-30 |
2023-08-13 |
mouse |
| Arunkumar Singh Koijam, Aruna Chanu Hijam, Asem Surindro Singh, Preeti Jaiswal, Kanchan Mukhopadhyay, Usha Rajamma, Reena Haoba. Association of Dopamine Transporter Gene with Heroin Dependence in an Indian Subpopulation from Manipur. Journal of molecular neuroscience : MN. vol 71. issue 1. 2021-08-27. PMID:32557146. |
dopamine transporter (dat) or solute carrier family 6 member 3 (slc6a3) is a transmembrane protein regulating dopaminergic neurotransmission. |
2021-08-27 |
2023-08-13 |
Not clear |