| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chao Ren, Fen Wang, Kai-Jie He, Yu-Ting Zhang, Ling-Xi Li, Jin-Bao Zhang, Jing Chen, Cheng-Jie Mao, Chun-Feng Li. Early-life stress induces prodromal features of Parkinsonian with aging in rats. The journals of gerontology. Series A, Biological sciences and medical sciences. 2021-08-27. PMID:34448826. |
based on neuroimaging and histochemistry, although we found that the dopaminergic system in striatum was impaired after ms, the decrease of striatal dopamine level was ~33%. |
2021-08-27 |
2023-08-13 |
human |
| Caline S Karam, Brenna L Williams, Sandra K Jones, Jonathan A Javitc. The Role of the Dopamine Transporter in the Effects of Amphetamine on Sleep and Sleep Architecture in Drosophila. Neurochemical research. 2021-08-26. PMID:33630236. |
the dopamine transporter (dat) mediates the inactivation of released dopamine (da) through its reuptake, and thereby plays an important homeostatic role in dopaminergic neurotransmission. |
2021-08-26 |
2023-08-13 |
drosophila_melanogaster |
| Denis Pavăl, Ioana Valentina Micluți. The Dopamine Hypothesis of Autism Spectrum Disorder Revisited: Current Status and Future Prospects. Developmental neuroscience. vol 43. issue 2. 2021-08-25. PMID:34010842. |
in 2017, we provided a theoretical framework for a "dopamine hypothesis of asd" which proposed that autistic behavior arises from a dysfunctional midbrain dopaminergic system. |
2021-08-25 |
2023-08-13 |
Not clear |
| Nii A Add. An ongoing saga of nicotine complexity and dopamine heterogeneity: Nicotine activation and inhibition mediating reward and anxiety. Neuron. vol 109. issue 16. 2021-08-25. PMID:34411537. |
their findings provide new understanding of the functional role of ventral tegmental area (vta) dopamine neurons and reveal topographically distinct, pathway-specific, and opposite dopaminergic responses to nicotine that likely mediate reward and anxiety, respectively. |
2021-08-25 |
2023-08-13 |
Not clear |
| Mikhail Melnikov, Anastasiya Sviridova, Vladimir Rogovskii, Vladimir Kudrin, Vladimir Murugin, Alexey Boyko, Mikhail Pashenko. The role of D2-like dopaminergic receptor in dopamine-mediated modulation of Th17-cells in multiple sclerosis. Current neuropharmacology. 2021-08-25. PMID:34429055. |
in contrast, blockade of d2-like dopaminergic receptor by sulpiride decreased dopamine's inhibitory effect on il-17 secretion in both groups and gm-csf and il-21 production in ms patients. |
2021-08-25 |
2023-08-13 |
human |
| Mikhail Melnikov, Anastasiya Sviridova, Vladimir Rogovskii, Vladimir Kudrin, Vladimir Murugin, Alexey Boyko, Mikhail Pashenko. The role of D2-like dopaminergic receptor in dopamine-mediated modulation of Th17-cells in multiple sclerosis. Current neuropharmacology. 2021-08-25. PMID:34429055. |
these data suggest an inhibitory role of dopamine on th17-cells in ms, which could be mediated by the activation of d2-like dopaminergic receptor. |
2021-08-25 |
2023-08-13 |
human |
| Tuane Bazanella Sampaio, Filipe Neimaier Bilheri, Gilson Rogério Zeni, Cristina Wayne Nogueir. Dopaminergic system contribution to the antidepressant-like effect of 3-phenyl-4-(phenylseleno) isoquinoline in mice. Behavioural brain research. vol 386. 2021-08-24. PMID:32184159. |
lastly, the contribution of dopaminergic system in the psi antidepressant-like effect was demonstrated by using dopamine receptors antagonists, sch23390, haloperidol and sulpiride. |
2021-08-24 |
2023-08-13 |
mouse |
| Avila G, Picazo O, Chuc-Meza E, García-Ramirez . Reduction of dopaminergic transmission in the globus pallidus increases anxiety-like behavior without altering motor activity. Behavioural brain research. vol 386. 2021-08-24. PMID:32194191. |
since the gp receives dopaminergic innervation from the substantia nigra pars compacta (snc), it is important to determine whether a local dopamine (da) deficit in the gp is related not only to motor but also to the cognitive and emotional alterations of pd. |
2021-08-24 |
2023-08-13 |
rat |
| M Frankowska, J Miszkiel, L Pomierny-Chamiolo, B Pomierny, A Celeste Borelli, A Suder, M Fili. The impact of 3,4-methylendioxymetamphetamine (MDMA) abstinence on seeking behavior and the expression of the D Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 71. issue 4. 2021-08-24. PMID:33316768. |
there is also strong evidence showing the engagement of brain dopaminergic and glutamatergic signaling through the dopamine d |
2021-08-24 |
2023-08-13 |
Not clear |
| Paolo Flace, Paolo Livrea, Gianpaolo Antonio Basile, Diana Galletta, Antonella Bizzoca, Gianfranco Gennarini, Salvatore Bertino, Jacopo Junio Valerio Branca, Massimo Gulisano, Simona Bianconi, Alessia Bramanti, Giuseppe Anastas. The Cerebellar Dopaminergic System. Frontiers in systems neuroscience. vol 15. 2021-08-24. PMID:34421548. |
although the cerebellum is not been considered an elective dopaminergic region, studies attributed to it a critical role in dopamine deficit-related neurological and psychiatric disorders [e.g., parkinson's disease (pd) and schizophrenia (scz)]. |
2021-08-24 |
2023-08-13 |
Not clear |
| Paolo Flace, Paolo Livrea, Gianpaolo Antonio Basile, Diana Galletta, Antonella Bizzoca, Gianfranco Gennarini, Salvatore Bertino, Jacopo Junio Valerio Branca, Massimo Gulisano, Simona Bianconi, Alessia Bramanti, Giuseppe Anastas. The Cerebellar Dopaminergic System. Frontiers in systems neuroscience. vol 15. 2021-08-24. PMID:34421548. |
nevertheless, biochemical studies detected in the mammalians cerebellum high dopamine levels, while chemical neuroanatomy studies revealed the presence of midbrain dopaminergic afferents to the cerebellum as well as wide distribution of the dopaminergic receptor subtypes (drd |
2021-08-24 |
2023-08-13 |
Not clear |
| G Tavares, D Marques, C Barra, D Rosendo-Silva, A Costa, T Rodrigues, P Gasparini, B F Melo, J F Sacramento, R Seiça, S V Conde, P Matafom. Dopamine D2 receptor agonist, bromocriptine, remodels adipose tissue dopaminergic signalling and upregulates catabolic pathways, improving metabolic profile in type 2 diabetes. Molecular metabolism. vol 51. 2021-08-23. PMID:33933677. |
dopamine d2 receptor agonist, bromocriptine, remodels adipose tissue dopaminergic signalling and upregulates catabolic pathways, improving metabolic profile in type 2 diabetes. |
2021-08-23 |
2023-08-13 |
Not clear |
| Prashant Donthamsetti, Nils Winter, Adam Hoagland, Cherise Stanley, Meike Visel, Stephan Lammel, Dirk Trauner, Ehud Isacof. Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors. Nature communications. vol 12. issue 1. 2021-08-23. PMID:34362914. |
our ability to understand and manipulate the function of dopamine is limited by the heterogenous nature of dopaminergic projections, the diversity of neurons that are regulated by dopamine, the varying distribution of the five dopamine receptors (dars), and the complex dynamics of dopamine release. |
2021-08-23 |
2023-08-13 |
Not clear |
| I M Vialichko, S V Lelevich, V V Lelevich, E M Doroshenko, V Yu Smirno. [Neurotransmitter changes in the rat brain under combined intoxication induced by alcohol and morphine]. Biomeditsinskaia khimiia. vol 67. issue 4. 2021-08-23. PMID:34414890. |
there are features of changes in the indices of the dopaminergic and serotonergic systems in these experimental conditions, confirmed by the processes of dopamine catabolism and a decrease in the norepinephrine and serotonin concentration in the hypothalamus, which are not observed under individual action of ethanol and morphine. |
2021-08-23 |
2023-08-13 |
rat |
| Natalie Hong Siu Chang, Yoshitaka Kumakura, Arne Møller, Jakob Linnet, Dirk Bender, Doris J Doudet, Manouchehr Seyedi Vafaee, Albert Gjedd. On the learning of addictive behavior: Sensation-seeking propensity predicts dopamine turnover in dorsal striatum. Brain imaging and behavior. 2021-08-21. PMID:34417966. |
we previously determined dopaminergic receptor density in striatum, and we now tested the hypothesis that an elevated dopaminergic condition with increased extracellular dopamine and receptor density follows increased dopamine synthesis capacity in highly sensation-seeking individuals, as measured by positron emission tomography of 18 men with tracer fluorodopa (fdopa). |
2021-08-21 |
2023-08-13 |
human |
| Aimée I Vester, Karen Hermetz, Amber Burt, Todd Everson, Carmen J Marsit, William M Caudl. Combined neurodevelopmental exposure to deltamethrin and corticosterone is associated with Nr3c1 hypermethylation in the midbrain of male mice. Neurotoxicology and teratology. vol 80. 2021-08-20. PMID:32348866. |
work from our group and that of others indicates that deltamethrin insecticide and stress exposure during neurodevelopment leads to alterations in dopamine function, and we hypothesized that exposure to both of these factors together would lead to synergistic effects on dna methylation of key genes within the midbrain, a highly dopaminergic region, that could contribute to these findings. |
2021-08-20 |
2023-08-13 |
mouse |
| Cian-Ling Jhang, Hom-Yi Lee, Jin-Chung Chen, Wenlin Lia. Dopaminergic loss of cyclin-dependent kinase-like 5 recapitulates methylphenidate-remediable hyperlocomotion in mouse model of CDKL5 deficiency disorder. Human molecular genetics. vol 29. issue 14. 2021-08-18. PMID:32588892. |
finally, mice carrying a cdkl5 deletion selectively in dat-expressing dopaminergic neurons, but not dopamine receptive neurons, recapitulated the hyperlocomotion phenotype found in cdkl5 null mice. |
2021-08-18 |
2023-08-13 |
mouse |
| Tapan Behl, Ishnoor Kaur, Arun Kumar, Vineet Mehta, Gokhan Zengin, Sandeep Aror. Gene Therapy in the Management of Parkinson's Disease: Potential of GDNF as a Promising Therapeutic Strategy. Current gene therapy. vol 20. issue 3. 2021-08-18. PMID:32811394. |
multiple treatment options targeting dopaminergic neuronal regeneration, production of enzymes linked with dopamine synthesis, subthalamic nucleus neurons, regulation of astrocytes and microglial cells and potentiating neurotrophic factors, were established. |
2021-08-18 |
2023-08-13 |
Not clear |
| Ekaterina Dobryakova, Suzanne Zuckerman, Joshua Sandr. Neural correlates of extrinsic and intrinsic outcome processing during learning in individuals with TBI: a pilot investigation. Brain imaging and behavior. 2021-08-18. PMID:34406636. |
animal research shows that damage to dopaminergic pathways in the brain can lead to a disruption of dopamine tone and transmission. |
2021-08-18 |
2023-08-13 |
human |
| Kaavya Jayaramayya, Mahalaxmi Iyer, Dhivya Venkatesan, Venkatesh Balasubramanian, Arul Narayanasamy, Mohana Devi Subramaniam, Ssang Goo Cho, Balachandar Vellingir. Unraveling correlative roles of dopamine transporter (DAT) and Parkin in Parkinson's disease (PD) - A road to discovery? Brain research bulletin. vol 157. 2021-08-17. PMID:32035946. |
parkinson's disease (pd) is a neurodegenerative disorder accompanied by depletion of dopamine(da) and loss of dopaminergic (daergic) neurons in the brain that is believed to be responsible for the motor and non-motor symptoms of pd. |
2021-08-17 |
2023-08-13 |
Not clear |