| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B R Bloem, D J Beckley, J G van Dijk, A H Zwinderman, M P Remler, J W Langston, R A Roo. Medium latency stretch reflexes in young-onset Parkinson's disease and MPTP-induced parkinsonism. Journal of the neurological sciences. vol 123. issue 1-2. 1994-09-19. PMID:8064321. |
to assess the contribution of supraspinal dopaminergic influences, we also studied 5 young parkinsonian patients with a selective central dopamine deficiency induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
1994-09-19 |
2023-08-12 |
human |
| A J Stoess. Localization of striatal and nigral tachykinin receptors in the rat. Brain research. vol 646. issue 1. 1994-09-15. PMID:7519961. |
these findings suggest that both nk-1 and nk-3 receptors within the striatum are predominantly post-synaptic with respect to dopamine neurons, whereas nigral nk-3 receptors are located on dopaminergic neurons. |
1994-09-15 |
2023-08-12 |
rat |
| J H Meador-Woodruff, S P Damask, S J Watso. Differential expression of autoreceptors in the ascending dopamine systems of the human brain. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 17. 1994-09-14. PMID:7914704. |
the tone and regulation of the brain dopaminergic projections are, in part, determined by the presence or absence of dopamine (da) autoreceptors: rate of da synthesis and turnover, as well as both pattern and rate of neuronal firing, are modulated by the expression and activity of these autoreceptors. |
1994-09-14 |
2023-08-12 |
rat |
| K Akiyama, A Kanzaki, K Tsuchida, H Ujik. Methamphetamine-induced behavioral sensitization and its implications for relapse of schizophrenia. Schizophrenia research. vol 12. issue 3. 1994-09-13. PMID:8054317. |
the initiation of behavioral sensitization to map in rats requires stimulation of dopaminergic neurons, and can be blocked by sch 23390 (a dopamine d1-receptor antagonist) and bmy 14802 (a sigma-receptor antagonist). |
1994-09-13 |
2023-08-12 |
rat |
| D M Bronstein, H Ye, K R Pennypacker, P M Hudson, J S Hon. Role of a 35 kDa fos-related antigen (FRA) in the long-term induction of striatal dynorphin expression in the 6-hydroxydopamine lesioned rat. Brain research. Molecular brain research. vol 23. issue 3. 1994-09-12. PMID:7914658. |
d1 dopamine (da) receptor agonists induce the expression of the opioid peptide dynorphin (dyn) in the striatum, an effect accentuated several fold by removing the dopaminergic innervation to the striatum (e.g., by lesioning the da cell bodies in the substantia nigra [sn]). |
1994-09-12 |
2023-08-12 |
rat |
| D Ebert, H Feistel, W Kaschka, A Barocka, A Pirne. Single photon emission computerized tomography assessment of cerebral dopamine D2 receptor blockade in depression before and after sleep deprivation--preliminary results. Biological psychiatry. vol 35. issue 11. 1994-09-12. PMID:8054411. |
the results confirm previous hypotheses of dopaminergic involvement in the therapeutic action of tsd and indirectly support a dopamine hypotheses of depression. |
1994-09-12 |
2023-08-12 |
Not clear |
| C P Silvia, G R King, T H Lee, Z Y Xue, M G Caron, E H Ellinwoo. Intranigral administration of D2 dopamine receptor antisense oligodeoxynucleotides establishes a role for nigrostriatal D2 autoreceptors in the motor actions of cocaine. Molecular pharmacology. vol 46. issue 1. 1994-09-09. PMID:8058056. |
dopamine d2 autoreceptors found on nigrostriatal dopaminergic neurons are thought to inhibit dopamine release, tyrosine hydroxylase activation, and spontaneous firing rate. |
1994-09-09 |
2023-08-12 |
rat |
| D G Cole, M Di Figli. Reserpine increases Fos activity in the rat basal ganglia via a quinpirole-sensitive mechanism. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:7914358. |
because dopamine is believed to excite striatal neurons via d1 receptors and inhibit them via d2 receptors, we hypothesized that acute dopamine depletion would increase fos activity in basal ganglia circuits normally inhibited by dopaminergic input to d2 receptors. |
1994-09-08 |
2023-08-12 |
rat |
| T G Hastings, M J Zigmon. Identification of catechol-protein conjugates in neostriatal slices incubated with [3H]dopamine: impact of ascorbic acid and glutathione. Journal of neurochemistry. vol 63. issue 3. 1994-09-08. PMID:8051554. |
there is evidence to suggest that degeneration of dopaminergic neurons in parkinson's disease and certain other conditions results from the action of reactive species generated during the oxidation of dopamine. |
1994-09-08 |
2023-08-12 |
rat |
| S Ferré, R Cortés, F Artiga. Dopaminergic regulation of the serotonergic raphe-striatal pathway: microdialysis studies in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 8. 1994-08-30. PMID:7519257. |
morphological evidence demonstrates the existence of dopaminergic afferent pathways and dopamine (da)-containing neurons in the dorsal raphe nucleus (drn). |
1994-08-30 |
2023-08-12 |
rat |
| J D Salamon. The involvement of nucleus accumbens dopamine in appetitive and aversive motivation. Behavioural brain research. vol 61. issue 2. 1994-08-24. PMID:8037860. |
there is conflicting evidence about the role of dopamine in emotion, and little evidence to suggest that the profound and consistent changes in instrumental behavior produced by interference with da systems are due to direct dopaminergic mediation of positive affective responses such as hedonia. |
1994-08-24 |
2023-08-12 |
Not clear |
| P Simon, R Dupuis, J Costenti. Thigmotaxis as an index of anxiety in mice. Influence of dopaminergic transmissions. Behavioural brain research. vol 61. issue 1. 1994-08-16. PMID:7913324. |
finally, the simultaneous involvement of d1 and d2 dopamine receptors has been evidenced in the anxiogenic-like effect associated with an increase of dopaminergic transmissions. |
1994-08-16 |
2023-08-12 |
mouse |
| J L McDermott, J D Kreutzberg, B Liu, D E Dluze. Effects of estrogen treatment on sensorimotor task performance and brain dopamine concentrations in gonadectomized male and female CD-1 mice. Hormones and behavior. vol 28. issue 1. 1994-08-16. PMID:8034279. |
to evaluate whether behavioral performance was related to nigrostriatal dopaminergic function, tissue dopamine concentrations were determined from the corpus striatum as well as the hypothalamus and olfactory tubercle. |
1994-08-16 |
2023-08-12 |
mouse |
| L F Lin, T J Zhang, F Collins, L G Arme. Purification and initial characterization of rat B49 glial cell line-derived neurotrophic factor. Journal of neurochemistry. vol 63. issue 2. 1994-08-12. PMID:8035200. |
the purified rat protein promotes the survival, morphological differentiation, and high-affinity dopamine reuptake of dopaminergic neurons in midbrain cultures, without obvious effects on total neurons or glia and without increasing high-affinity gaba or serotonin reuptake. |
1994-08-12 |
2023-08-12 |
human |
| W Asakura, K Matsumoto, H Ohta, H Watanab. Involvement of dopamine D2 receptor mechanism in the REM sleep deprivation-induced increase in swimming activity in the forced swimming test. Pharmacology, biochemistry, and behavior. vol 48. issue 1. 1994-08-10. PMID:7913230. |
these results suggest that rems deprivation treatment-induced increase in swimming activity is mainly due to the functional changes in the dopaminergic system rather than the noradrenergic or serotonergic system, and that dopamine d2 but not d1 receptor mechanism is involved in the increase in swimming activity in rems-deprived animals. |
1994-08-10 |
2023-08-12 |
mouse |
| N T Panagopoulos, N A Matsoki. Pharmacologic characterization of [3H]dopamine and [3H]spiperone binding in mouse cerebellum. General pharmacology. vol 25. issue 1. 1994-08-08. PMID:7913071. |
[3h]dopamine and [3h]spiperone binding to cerebellar homogenates was characterized utilizing dopaminergic agonists, antagonists and non-dopaminergic drugs. |
1994-08-08 |
2023-08-12 |
mouse |
| V Gayrard, B Malpaux, Y Tillet, J C Thiér. Estradiol increases tyrosine hydroxylase activity of the A15 nucleus dopaminergic neurons during long days in the ewe. Biology of reproduction. vol 50. issue 5. 1994-08-05. PMID:7912958. |
in experiment 2, we estimated the relative contribution to the accumulation of l-dopa in the lateral retrochiasmatic area by dopamine (da) synthesis in the dopaminergic neurons and noradrenaline (na) synthesis in the noradrenergic afferents of the a15 nucleus. |
1994-08-05 |
2023-08-12 |
Not clear |
| T Di Paol. Modulation of brain dopamine transmission by sex steroids. Reviews in the neurosciences. vol 5. issue 1. 1994-08-04. PMID:8019704. |
in view of the numerous variables that influence net dopaminergic response to steroids, focus will be on the literature using similar experimental conditions to assess the effect of in vivo chronic steroid treatment, acute short-term steroid treatment and the estrous cycle as well as in vitro effects of steroids on dopamine receptors. |
1994-08-04 |
2023-08-12 |
rat |
| J G Temple, G T Barthalmu. Effects of monoamine oxidase inhibitors and dopamine agonists on the behavior of mammal- and frog-eating snakes. Physiology & behavior. vol 55. issue 5. 1994-08-02. PMID:7912837. |
results suggest that dopaminergic stimulation by mao-bi and dopamine agonists modulates tongue flicking and climbing behaviors in snakes, and that the contrasting climbing reactions induced by mao-bi between elaphe and nerodia may be linked to quantitative differences in endogenous catecholamine levels and/or to the numbers and sensitivity of receptors. |
1994-08-02 |
2023-08-12 |
rat |
| M Santiago, A Machado, J Can. Effect of L-arginine/nitric oxide pathway on MPP(+)-induced cell injury in the striatum of rats. British journal of pharmacology. vol 111. issue 3. 1994-08-02. PMID:8019760. |
protection against 1-methyl-4-phenylpyridinium ion (mpp+) neurotoxicity by two nitric oxide-related compounds, n omega-nitro-l-arginine (l-noarg) and l-arginine, was studied in the corpus striatum by means of two mpp+ perfusions separated by 24 h. dopamine extracellular output after the second mpp+ (1, 5 and 10 mm) perfusion was considered as an index of the dopaminergic neurone damage produced by the first mpp+ (1, 5 and 10 mm) perfusion. |
1994-08-02 |
2023-08-12 |
rat |