| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C A Leslie, M W Robertson, A B Jung, J Liebermann, J P Bennet. Effects of prenatal cocaine exposure upon postnatal development of neostriatal dopaminergic function. Synapse (New York, N.Y.). vol 17. issue 3. 1994-11-29. PMID:7974205. |
brains from offspring were examined with quantitative receptor autoradiography [d1 receptor (d1r), d2 receptor (d2r) and dopamine transporter (dat)] and quantitative in situ hybridization [d1r mrna, d2r mrna, preproenkephalin (ppe) mrna] for markers of neostriatal dopaminergic function. |
1994-11-29 |
2023-08-12 |
rat |
| B Moghadda. Preferential activation of cortical dopamine neurotransmission by clozapine: functional significance. The Journal of clinical psychiatry. vol 55 Suppl B. 1994-11-28. PMID:7961567. |
the ability of clozapine to increase dopamine release in the prefrontal cortex and its relatively weak affinity for some types of dopamine receptors suggest that this drug may exert its therapeutic influence in part by increasing dopaminergic function in the prefrontal cortex. |
1994-11-28 |
2023-08-12 |
Not clear |
| S Gobaille, C Schmidt, A Cupo, F Herbrecht, M Maitr. Characterization of methionine-enkephalin release in the rat striatum by in vivo dialysis: effects of gamma-hydroxybutyrate on cellular and extracellular methionine-enkephalin levels. Neuroscience. vol 60. issue 3. 1994-11-17. PMID:7936191. |
from a functional point of view, the dopaminergic d2 receptor blockade or the gamma-hydroxybutyrate-induced inhibition of dopamine release could be considered to induce similar results, with identical consequences on striatal met-enkephalin accumulation and release. |
1994-11-17 |
2023-08-12 |
rat |
| J D Sokolowski, L D McCullough, J D Salamon. Effects of dopamine depletions in the medial prefrontal cortex on active avoidance and escape in the rat. Brain research. vol 651. issue 1-2. 1994-11-16. PMID:7922578. |
dopamine systems have been implicated in the performance of avoidance behavior, and the dopaminergic innervation of medial prefrontal cortex is known to be responsive to stressful stimuli. |
1994-11-16 |
2023-08-12 |
rat |
| P A Garris, E L Ciolkowski, P Pastore, R M Wightma. Efflux of dopamine from the synaptic cleft in the nucleus accumbens of the rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 14. issue 10. 1994-11-14. PMID:7931564. |
synaptic release of dopamine in the nucleus accumbens of the intact rat brain elicited by a single electrical impulse applied to ascending dopaminergic fibers results in extracellular concentrations sufficient to bind the known dopamine receptors. |
1994-11-14 |
2023-08-12 |
rat |
| B Bowery, L A Rothwell, G R Seabroo. Comparison between the pharmacology of dopamine receptors mediating the inhibition of cell firing in rat brain slices through the substantia nigra pars compacta and ventral tegmental area. British journal of pharmacology. vol 112. issue 3. 1994-11-09. PMID:7921615. |
comparison of these data with the binding affinity for cloned dopamine receptors demonstrates that the responses to quinpirole on dopaminergic neurones in both the a9 (substantia nigra) and a10(ventral tegmental area) brain areas are consistent with the activation of predominantly d2, and not d3 or d4 dopamine receptors. |
1994-11-09 |
2023-08-12 |
rat |
| N K Mello, J H Mendelson, J M Drieze, S K Teoh, M L Kelly, J W Shola. Effects of dopamine on prolactin: interactions with cocaine self-administration by female rhesus monkeys. The Journal of pharmacology and experimental therapeutics. vol 270. issue 3. 1994-11-07. PMID:7932159. |
these data suggest that the prolactin secretory response to dopamine perturbation may provide a sensitive index of changes in dopaminergic regulation of prolactin during chronic cocaine exposure. |
1994-11-07 |
2023-08-12 |
monkey |
| E M Unterwald, A Ho, J M Rubenfeld, M J Kree. Time course of the development of behavioral sensitization and dopamine receptor up-regulation during binge cocaine administration. The Journal of pharmacology and experimental therapeutics. vol 270. issue 3. 1994-11-07. PMID:7932193. |
cocaine is a widely abused psychomotor stimulant that potentiates dopaminergic neurotransmission by inhibiting the re-uptake of dopamine. |
1994-11-07 |
2023-08-12 |
human |
| M A Bozarth, C M Pudiak, M Morri. Nitric oxide synthesis inhibition does not affect brain stimulation reward. Pharmacology, biochemistry, and behavior. vol 48. issue 2. 1994-10-20. PMID:8090819. |
despite reports that nitric oxide may modulate dopamine release, these data suggest that nitric oxide is not involved in the dopamine-dependent rewarding effect of electrical brain stimulation or the reward facilitation produced by cocaine's enhancement of dopaminergic activity. |
1994-10-20 |
2023-08-12 |
Not clear |
| I Hirotsu, M Koyama, N Honbo, T Ohn. Pharmacological characteristics of hyperambulation induced by the sigma ligand (+)-3-PPP in rats. Japanese journal of pharmacology. vol 65. issue 1. 1994-10-19. PMID:7916383. |
these results indicate that sigma receptors are involved in the neuronal mechanism(s) of hyperambulation induced by (+)-3-ppp, and the sigma system may exert both a presynaptic action and a dopamine d2 receptor-mediated action to increase the central dopaminergic function. |
1994-10-19 |
2023-08-12 |
rat |
| C Perrone-Capano, A Tino, U di Porzi. Target cells modulate dopamine transporter gene expression during brain development. Neuroreport. vol 5. issue 9. 1994-10-11. PMID:7521683. |
we have analysed the expression of the dopamine transporter (dat) gene and compared it with that of tyrosine hydroxylase, neuronal gaba transporter and synaptic vesicle monoamine transporter genes during pre- and post-natal development of rat mesencephalic dopaminergic (da) neurones. |
1994-10-11 |
2023-08-12 |
rat |
| R Sandy. The relationship between diabetes mellitus and Parkinson's disease. The International journal of neuroscience. vol 69. issue 1-4. 1994-10-11. PMID:8082998. |
this issue, which has been largely ignored, is of clinical relevance since animal studies indicate that chronic hyperglycemia decreases striatal dopaminergic transmission and increases the sensitivity of postsynaptic dopamine receptors. |
1994-10-11 |
2023-08-12 |
rat |
| E R Larson, M A Arian. Dopamine receptor binding on identified striatonigral neurons. Neuroscience letters. vol 172. issue 1-2. 1994-10-11. PMID:8084509. |
determining the specific cellular location for these dopamine receptors in the striatum is important to the design of drug treatments for disorders with suspected dopaminergic involvement such as parkinson's disease. |
1994-10-11 |
2023-08-12 |
Not clear |
| A Zouakia, S Chalon, H F Kung, A M Dognon, E Saliba, J C Besnard, D Guillotea. Radioiodinated tracers for the evaluation of dopamine receptors in the neonatal rat brain after hypoxic-ischemic injury. European journal of nuclear medicine. vol 21. issue 6. 1994-10-10. PMID:8082661. |
two weeks later, in brains with no visible loss of hemispheric volume, striatal dopaminergic receptors were studied, with [125i]tisch and [125i]ibzm for the d1 and d2 dopamine receptors, respectively. |
1994-10-10 |
2023-08-12 |
human |
| A Meier-Hellmann, L Hannemann, M Specht, W Schaffartzik, C Spies, K Reinhar. The relationship between mixed venous and hepatic venous O2 saturation in patients with septic shock. Advances in experimental medicine and biology. vol 345. 1994-10-06. PMID:7915869. |
alpha-mimetic substances such as epinephrine and norepinephrine reduced shvo2 and increased the difference between svo2 and shvo2.beta2-mimetic and dopaminergic substances (dopexamine, dopamine) did not change the difference between svo2 and shvo2. |
1994-10-06 |
2023-08-12 |
Not clear |
| L Tang, R D Todd, K L O'Malle. Dopamine D2 and D3 receptors inhibit dopamine release. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071839. |
here we report that stimulation of transfected d2 and d3 receptors, but not d4 receptors, inhibits dopamine release from this dopaminergic cell line. |
1994-09-28 |
2023-08-12 |
Not clear |
| J Bloomquist, E King, A Wright, C Mytilineou, K Kimura, K Castagnoli, N Castagnol. 1-Methyl-4-phenylpyridinium-like neurotoxicity of a pyridinium metabolite derived from haloperidol: cell culture and neurotransmitter uptake studies. The Journal of pharmacology and experimental therapeutics. vol 270. issue 2. 1994-09-28. PMID:8071874. |
this article reports that hpp+ also is toxic to dopaminergic and serotonergic neurons in cultures of embryonic mesencephalic cells, as measured by loss of the ability of exposed cells to accumulate tritium-labeled dopamine and serotonin and by immunochemical staining techniques. |
1994-09-28 |
2023-08-12 |
mouse |
| E P Noble, S T St Jeor, T Ritchie, K Syndulko, S C St Jeor, R J Fitch, R L Brunner, R S Sparke. D2 dopamine receptor gene and cigarette smoking: a reward gene? Medical hypotheses. vol 42. issue 4. 1994-09-26. PMID:8072432. |
in as much as alcohol, cocaine, opiates, nicotine and food are known to increase brain dopamine levels and activate the mesocorticolimbic dopaminergic reward pathways of the brain, it is hypothesized that an inherited deficit of d2 dopamine receptor numbers in brain reward areas of a1 allelic subject predisposes them to substance abuse problems. |
1994-09-26 |
2023-08-12 |
human |
| M G Rosales, G Flores, S Hernández, D Martínez-Fong, J Aceve. Activation of subthalamic neurons produces NMDA receptor-mediated dendritic dopamine release in substantia nigra pars reticulata: a microdialysis study in the rat. Brain research. vol 645. issue 1-2. 1994-09-21. PMID:8062095. |
here we have studied whether the activation of the subthalamic neurons induces the release of dopamine (da) from dopaminergic dendrites in the pars reticulata of the substantia nigra. |
1994-09-21 |
2023-08-12 |
rat |
| K Sumii, M Munemori, H Miyoshi, I Seyam. Intracellular signal transduction systems do not regulate Na channel in frog ventricular cells. The American journal of physiology. vol 267. issue 2 Pt 2. 1994-09-21. PMID:8067411. |
1-oleoyl-2-acetyl-sn-glycerol (40 microm) and 12-o-tetradecanoylphorbol-13-acetate (80-800 nm) were used to activate protein kinase c, and phenylephrine (0.1-10 microm), dopamine (0.1-10 microm), and histamine (10 microm) were used to stimulate alpha-adrenergic, dopaminergic, and histaminergic receptors, respectively. |
1994-09-21 |
2023-08-12 |
Not clear |