| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Tirelli, J M Witki. Verticalization of behavior elicited by dopaminergic mobilization is qualitatively different between C57BL/6J and DBA/2J mice. Psychopharmacology. vol 116. issue 2. 1995-03-22. PMID:7862948. |
the present data do not support a unitary, purely quantitative, account of insensitivity to dopaminergic stimulation based upon low densities of striatal dopamine receptors in dba/2j mice. |
1995-03-22 |
2023-08-12 |
mouse |
| R C Shelto. The role of sertraline in the management of depression. Clinical therapeutics. vol 16. issue 5. 1995-03-21. PMID:7859236. |
it exerts no clinically significant effects on norepinephrine and dopamine uptake and possess negligible binding affinity for histaminergic, muscarinic, dopaminergic, and adrenergic receptors. |
1995-03-21 |
2023-08-12 |
Not clear |
| H Kuribar. Potentiation of the ambulation-increasing effect induced by combined administration of MK-801 with ethanol in mice. Psychopharmacology. vol 113. issue 3-4. 1995-03-20. PMID:7862858. |
these results suggest that the dopaminergic system, particularly via presynaptic changes in the release of stored dopamine, as well as the opioid system, are involved in the interaction of mk-801 with ethanol. |
1995-03-20 |
2023-08-12 |
mouse |
| S A Tanco, N V Watson, B B Gorzalk. Effects of 5-HT3 agonists on reproductive behaviors in rats. Psychopharmacology. vol 115. issue 1-2. 1995-03-20. PMID:7862902. |
evidence that pbg, but not 2-me-5-ht, induces carrier-mediated dopamine release suggests that the effect of pbg in male rats is due to dopaminergic mediation. |
1995-03-20 |
2023-08-12 |
rat |
| T Maeda, K Kitahama, M Geffar. Dopaminergic innervation of rat locus coeruleus: a light and electron microscopic immunohistochemical study. Microscopy research and technique. vol 29. issue 3. 1995-03-16. PMID:7849325. |
dopaminergic innervation of the rat locus coeruleus (lc) was immunohistochemically studied by using monoclonal antibody directed against dopamine (da) at the light- and electron-microscopic levels. |
1995-03-16 |
2023-08-12 |
rat |
| I Irwin, L E DeLanney, T McNeill, P Chan, L S Forno, G M Murphy, D A Di Monte, M S Sandy, J W Langsto. Aging and the nigrostriatal dopamine system: a non-human primate study. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 3. issue 4. 1995-03-09. PMID:7531106. |
however, nigrostriatal dopamine loss did not appear to be the consequence of age-related loss of dopaminergic nigral neurons since the number of tyrosine immunoreactive cells was not significantly different among the three age groups. |
1995-03-09 |
2023-08-12 |
monkey |
| J A Lago, T R Koste. Stimulant withdrawal. Addiction (Abingdon, England). vol 89. issue 11. 1995-03-08. PMID:7841859. |
another study using pet and f18-methylspiroperidol found decreased dopamine d2 receptor binding during cocaine withdrawal and also a separate study using pet and f-18-dopa discovered low dopaminergic brain activity. |
1995-03-08 |
2023-08-12 |
Not clear |
| B R Cooper, C M Wang, R F Cox, R Norton, V Shea, R M Ferri. Evidence that the acute behavioral and electrophysiological effects of bupropion (Wellbutrin) are mediated by a noradrenergic mechanism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 11. issue 2. 1995-03-07. PMID:7840865. |
bupropion (bw 323u66) has been considered a dopaminergic antidepressant based on its ability to inhibit the uptake of dopamine (da) somewhat more selectively than it inhibits uptake of norepinephrine (ne) or serotonin (5-ht). |
1995-03-07 |
2023-08-12 |
rat |
| P Anglade, S Tsuji, F Javoy-Agid, Y Agid, E C Hirsc. Plasticity of nerve afferents to nigrostriatal neurons in Parkinson's disease. Annals of neurology. vol 37. issue 2. 1995-03-07. PMID:7847868. |
clinical symptoms in parkinson's disease do not appear until almost total depletion of dopamine has occurred in the striatum, suggesting the existence of compensatory mechanisms to offset the loss of nigrostriatal dopaminergic neurons. |
1995-03-07 |
2023-08-12 |
human |
| P Anglade, S Tsuji, F Javoy-Agid, Y Agid, E C Hirsc. Plasticity of nerve afferents to nigrostriatal neurons in Parkinson's disease. Annals of neurology. vol 37. issue 2. 1995-03-07. PMID:7847868. |
this compensation has been attributed mainly to an increased turnover of dopamine in the remaining dopaminergic neurons. |
1995-03-07 |
2023-08-12 |
human |
| J C Day, C S Tham, H C Fibige. Dopamine depletion attenuates amphetamine-induced increases of cortical acetylcholine release. European journal of pharmacology. vol 263. issue 3. 1995-03-03. PMID:7843266. |
unilateral 6-hydroxydopamine lesions of the mesotelencephalic dopaminergic system, which depleted forebrain dopamine by 99% on the lesioned side, significantly attenuated the effect of d-amphetamine on cortical acetylcholine release compared to a surgical control group (160% baseline vs. 270%), suggesting that dopamine at least in part mediates this effect of d-amphetamine. |
1995-03-03 |
2023-08-12 |
rat |
| H Lilienthal, K Kohler, M Turfeld, G Winnek. Persistent increases in scotopic B-wave amplitudes after lead exposure in monkeys. Experimental eye research. vol 59. issue 2. 1995-02-28. PMID:7835409. |
taking into account, that dopamine antagonists cause similar changes in the erg, it is suggested that the observed effects may be mediated by a permanent change of dopaminergic processes since immunoreactivity also revealed adverse effects on the dopaminergic system in the retinae of these monkeys. |
1995-02-28 |
2023-08-12 |
monkey |
| S M Tomares, O S Bamford, L M Sterni, R S Fitzgerald, J L Carrol. Effects of domperidone on neonatal and adult carotid chemoreceptors in the cat. Journal of applied physiology (Bethesda, Md. : 1985). vol 77. issue 3. 1995-02-28. PMID:7836131. |
it has been postulated that the weak carotid chemoreceptor responses of neonatal mammals may be due to inhibition produced by high levels of endogenous dopamine release or exaggerated sensitivity to dopaminergic inhibition. |
1995-02-28 |
2023-08-12 |
cat |
| K J Livak, J Rogers, J B Lichte. Variability of dopamine D4 receptor (DRD4) gene sequence within and among nonhuman primate species. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 2. 1995-02-22. PMID:7831304. |
the dopamine d4 receptor is one of five receptors known to function in mammalian dopaminergic pathways. |
1995-02-22 |
2023-08-12 |
human |
| J L Cornish, M van den Buus. Pressor responses to electrical and chemical stimulation of the rat brain A10 dopaminergic system. Neuroscience letters. vol 176. issue 2. 1995-02-21. PMID:7530350. |
these results suggest that stimulation of dopaminergic neurons in the vta induces pressor responses and that projections from midbrain dopaminergic neurons, acting on dopamine d2 receptors, play a role in the regulation of blood pressure. |
1995-02-21 |
2023-08-12 |
rat |
| Z H Qin, B Weis. Dopamine receptor blockade increases dopamine D2 receptor and glutamic acid decarboxylase mRNAs in mouse substantia nigra. European journal of pharmacology. vol 269. issue 1. 1995-02-21. PMID:7828655. |
to study the influence of dopaminergic activity on the expression of dopamine d2 receptors and glutamic acid decarboxylase in substantia nigra, mice were treated daily for several days with an irreversibly acting dopamine d1 and dopamine d2 receptor antagonist n-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (eedq) or with a selective irreversible d2 dopamine receptor antagonist fluphenazine-n-mustard. |
1995-02-21 |
2023-08-12 |
mouse |
| J M Vile, U M D'Souza, P G Strang. [3H]nemonapride and [3H]spiperone label equivalent numbers of D2 and D3 dopamine receptors in a range of tissues and under different conditions. Journal of neurochemistry. vol 64. issue 2. 1995-02-21. PMID:7830089. |
[3h]nemonapride and [3h]spiperone are very widely used to study dopaminergic systems in vitro and in vivo, but it has been reported that [3h]nemonapride and [3h]spiperone give markedly different bmax values for preparations of d2 dopamine receptors from recombinant cell lines or animal tissues. |
1995-02-21 |
2023-08-12 |
Not clear |
| S Hernández-López, J L Góngora-Alfaro, D Martínez-Fong, M G Rosales, J Aceve. Cholinergic stimulation of rostral and caudal substantia nigra pars compacta produces opposite effects on circling behavior and striatal dopamine release measured by brain microdialysis. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830890. |
we conclude that the cholinergic input to the substantia nigra pars compacta could modulate the motor behavior through regulating the firing rate of nigrostriatal dopaminergic neurons and dopamine release in the neostriatum. |
1995-02-17 |
2023-08-12 |
rat |
| A Kastner, P Anglade, C Bounaix, P Damier, F Javoy-Agid, N Bromet, Y Agid, E C Hirsc. Immunohistochemical study of catechol-O-methyltransferase in the human mesostriatal system. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830891. |
thus, the catabolic degradation of striatal released dopamine by its o-methylation may involve postsynaptic neurons rather than dopaminergic presynaptic neurons. |
1995-02-17 |
2023-08-12 |
human |
| A Kastner, P Anglade, C Bounaix, P Damier, F Javoy-Agid, N Bromet, Y Agid, E C Hirsc. Immunohistochemical study of catechol-O-methyltransferase in the human mesostriatal system. Neuroscience. vol 62. issue 2. 1995-02-17. PMID:7830891. |
the presence of catechol-o-methyltransferase in some dopaminergic neurons of the ventral tegmental area and substantia nigra pars lateralis suggests that methylation of dopamine may occur in these neurons, which may consequently be better protected against dopamine auto-oxidation than those of the substantia nigra pars compacta. |
1995-02-17 |
2023-08-12 |
human |