| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S M Waters, C S Konkoy, T P Davi. Haloperidol and apomorphine differentially affect neuropeptidase activity. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613907. |
in view of the interaction between mesocorticolimbic dopamine neurons and neuropeptides, e.g., substance p, neurotensin and enkephalins, neuroleptic-induced alterations in the activities of neuropeptidases, and thus neuropeptide metabolism can, in turn, play a role in modulating midbrain dopaminergic activity. |
1996-06-06 |
2023-08-12 |
rat |
| J B Acri, B K Siedleck, J M Witki. Effects of benztropine on behavioral and toxic effects of cocaine: comparison with atropine and the selective dopamine uptake inhibitor 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine. The Journal of pharmacology and experimental therapeutics. vol 277. issue 1. 1996-06-06. PMID:8613919. |
because of the mixed pharmacology of benztropine which includes antimuscarinic as well as dopaminergic actions, results obtained from parallel experiments with atropine and the selective dopamine uptake inhibitor, gbr 12935 (1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-propyl)-piperazine), were performed. |
1996-06-06 |
2023-08-12 |
mouse |
| V E Shashoua, G W Hess. N-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite. Life sciences. vol 58. issue 16. 1996-06-05. PMID:8614292. |
n-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite. |
1996-06-05 |
2023-08-12 |
mouse |
| V E Shashoua, G W Hess. N-docosahexaenoyl, 3 hydroxytyramine: a dopaminergic compound that penetrates the blood-brain barrier and suppresses appetite. Life sciences. vol 58. issue 16. 1996-06-05. PMID:8614292. |
fatty acids with varying chain lengths (2-22 carbon atoms long) and degrees of unsaturation (0-6 double bonds) were used to synthesize dopaminergic compounds for a study of the carrier mediated transport of dopamine (da) to the brain. |
1996-06-05 |
2023-08-12 |
mouse |
| S M Efange, R B Langason, A B Khare, W C Lo. The vesamicol receptor ligand (+)-meta-[125I]iodobenzyltrozamicol [(+)-[125I]-MIBT] reveals blunting of the striatal cholinergic response to dopamine D2 receptor blockade in the 6-hydroxydopamine (6-OHDA)-lesioned rat: possible implications for Parkinson's disease. Life sciences. vol 58. issue 16. 1996-06-05. PMID:8614294. |
since the nigrostriatal dopaminergic system modulates striatal cholinergic function, and dopamine d2 receptor blockade is known to result in increased striatal cholinergic function, the refractoriness of striatal cholinergic neurons following the loss of nigrostriatal dopaminergic innervation confirms the existence of a dopaminergic-cholinergic imbalance in parkinson's disease. |
1996-06-05 |
2023-08-12 |
rat |
| J Balthazart, A Foidart, P Absil, N Harad. Effects of testosterone and its metabolites on aromatase-immunoreactive cells in the quail brain: relationship with the activation of male reproductive behavior. The Journal of steroid biochemistry and molecular biology. vol 56. issue 1-6 Spec No. 1996-05-16. PMID:8603040. |
fibers that are immunoreactive for tyrosine hydroxylase (synthesis of dopamine), dopamine beta-hydroxylase (synthesis of norepinephrine) or vasotocine have been identified in the close vicinity of aro-ir cells in the pom and retrograde tracing has identified the origin of the dopaminergic and noradrenergic innervation of these areas. |
1996-05-16 |
2023-08-12 |
rat |
| N Brunello, C Masotto, L Steardo, R Markstein, G Racagn. New insights into the biology of schizophrenia through the mechanism of action of clozapine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 13. issue 3. 1996-05-15. PMID:8602893. |
probably the d1 antagonistic activity exerted by clozapine at low doses enhances preferentially the extracellular concentration of dopamine in specific areas of the brain, such as the prefrontal cortex, where a dopaminergic hypoactivity has been suggested to be in part responsible for negative symptoms of schizophrenia. |
1996-05-15 |
2023-08-12 |
Not clear |
| V I Makolkin, V I Podzolkov, L G Ursova, T D Bol'shakova, T S Mel'nikov. [Pathogenetic aspects of early stages of hypertension and possibilities of non-drug treatment]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 10. 1996-05-09. PMID:8601082. |
there is markedly impaired secretion in the dopaminergic link of the sympathoadrenal system along with a steady-state increase in norepinephrine:dopamine ratio, which may be regarded as a possible marker (a risk factor) of hd progression. |
1996-05-09 |
2023-08-12 |
Not clear |
| K A Green, S J Harris, G A Cottrel. Dopamine directly activates a ligand-gated channel in snail neurones. Pflugers Archiv : European journal of physiology. vol 431. issue 4. 1996-04-18. PMID:8596710. |
unexpectedly, the fast response to dopamine was also observed in an identified dopaminergic neurone when maintained in isolation in culture. |
1996-04-18 |
2023-08-12 |
Not clear |
| J D Curlewis, J C Thiéry, B Malpau. Effect of hypothalamic infusion of a dopamine D1 receptor antagonist on prolactin secretion in the ewe. Brain research. vol 697. issue 1-2. 1996-04-11. PMID:8593594. |
these results are in accord with the hypothesis that dopaminergic pathways within the hypothalamus stimulate prolactin secretion via dopamine d1 receptors in the vmh. |
1996-04-11 |
2023-08-12 |
Not clear |
| B Delbarre, G Delbarre, C Rochat, F Calino. Effect of piribedil, a D-2 dopaminergic agonist, on dopamine, amino acids, and free radicals in gerbil brain after cerebral ischemia. Molecular and chemical neuropathology. vol 26. issue 1. 1996-03-25. PMID:8588823. |
effect of piribedil, a d-2 dopaminergic agonist, on dopamine, amino acids, and free radicals in gerbil brain after cerebral ischemia. |
1996-03-25 |
2023-08-12 |
Not clear |
| L A Anderson, J J Anderson, T N Chase, J R Walter. The cannabinoid agonists WIN 55,212-2 and CP 55,940 attenuate rotational behavior induced by a dopamine D1 but not a D2 agonist in rats with unilateral lesions of the nigrostriatal pathway. Brain research. vol 691. issue 1-2. 1996-03-25. PMID:8590042. |
the effect of cannabinoid receptor stimulation on rotational behavior induced by a dopamine d1 and a d2 agonist was studied in rats with unilateral 6-hydroxydopamine-induced lesions of the dopaminergic nigrostriatal pathway. |
1996-03-25 |
2023-08-12 |
rat |
| A N Singh, C Barlas, S Singh, P Franks, R K Mishr. A neurochemical basis for the antipsychotic activity of loxapine: interactions with dopamine D1, D2, D4 and serotonin 5-HT2 receptor subtypes. Journal of psychiatry & neuroscience : JPN. vol 21. issue 1. 1996-03-21. PMID:8580115. |
the findings indicate that loxapine displays an extremely strong binding affinity for dopamine d4 and serotonin 5-ht2 receptors, which suggests that both serotonergic and dopaminergic mechanisms contribute to the antipsychotic drug action and eps associated with loxapine in the treatment of schizophrenia. |
1996-03-21 |
2023-08-12 |
Not clear |
| E Nwanze, F Souverbie, G Jonsson, E Sundströ. Regional biotransformation of MPTP in the CNS of rodents and its relation to neurotoxicity. Neurotoxicology. vol 16. issue 3. 1996-03-18. PMID:8584278. |
neither previous lesions of catecholamine terminals in striatum or the frontal cortex, nor pretreatment with a dopamine uptake blocker affected the synthesis of mpp+, showing that the conversion of mptp to mpp+ is taking place outside both dopaminergic and noradrenergic neurons. |
1996-03-18 |
2023-08-12 |
mouse |
| A M Lin, C Y Cha. Dynamic analysis of ethanol effects on NMDA-evoked dopamine overflow in rat striatum. Brain research. vol 696. issue 1-2. 1996-03-14. PMID:8574663. |
this study was undertaken to dynamically examine the effects of ethanol on the striatal dopaminergic transmission, in terms of n-methyl-d-aspartate (nmda)-evoked dopamine release and dopamine uptake. |
1996-03-14 |
2023-08-12 |
rat |
| A M Lin, C Y Cha. Dynamic analysis of ethanol effects on NMDA-evoked dopamine overflow in rat striatum. Brain research. vol 696. issue 1-2. 1996-03-14. PMID:8574663. |
taken together, our data demonstrate that ethanol simultaneously inhibits nmda-evoked dopamine release and dopamine uptake in the striatum, suggesting the importance of the interplay between release and uptake in ethanol effects on striatal dopaminergic transmission. |
1996-03-14 |
2023-08-12 |
rat |
| K Matsubara, T Idzu, Y Kobayashi, D Nakahara, W Maruyama, S Kobayashi, K Kimura, M Nao. N-methyl-4-phenylpyridinium and an endogenously formed analog, N-methylated beta-carbolinium, inhibit striatal tyrosine hydroxylation in freely moving rats. Neuroscience letters. vol 199. issue 3. 1996-03-13. PMID:8577397. |
the present study revealed that mpp+ and 2,9-me2nh+ were taken up into dopaminergic neurons and then inhibited in vivo dopamine synthesis prior to cell death possibly in different manners. |
1996-03-13 |
2023-08-12 |
rat |
| F G de Araújo, H Romaldini, M Bogossian, J E Afonso, C Uehar. [Effect of dopamine in dopaminergic doses on pulmonary circulation of dogs in normoxia and hypoxia]. Arquivos brasileiros de cardiologia. vol 65. issue 3. 1996-03-13. PMID:8579510. |
[effect of dopamine in dopaminergic doses on pulmonary circulation of dogs in normoxia and hypoxia]. |
1996-03-13 |
2023-08-12 |
Not clear |
| F G de Araújo, H Romaldini, M Bogossian, J E Afonso, C Uehar. [Effect of dopamine in dopaminergic doses on pulmonary circulation of dogs in normoxia and hypoxia]. Arquivos brasileiros de cardiologia. vol 65. issue 3. 1996-03-13. PMID:8579510. |
to study if dopamine in dopaminergic doses (1.5 and 4.0 micrograms/kg/min) had some effect on the pulmonary vasoconstriction mechanism, and if in those doses the drug had some action on systemic and pulmonary hemodynamic variables, as well as in the pulmonary gas exchange. |
1996-03-13 |
2023-08-12 |
Not clear |
| S N Haber, H Ryoo, C Cox, W L. Subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mRNA for the dopamine transporter: comparison with the mRNA for the D2 receptor, tyrosine hydroxylase and calbindin immunoreactivity. The Journal of comparative neurology. vol 362. issue 3. 1996-03-12. PMID:8576447. |
subsets of midbrain dopaminergic neurons in monkeys are distinguished by different levels of mrna for the dopamine transporter: comparison with the mrna for the d2 receptor, tyrosine hydroxylase and calbindin immunoreactivity. |
1996-03-12 |
2023-08-12 |
monkey |