| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Pierre, M Mahouche, E I Suderevskaya, J Repérant, R War. Immunocytochemical localization of dopamine and its synthetic enzymes in the central nervous system of the lamprey Lampetra fluviatilis. The Journal of comparative neurology. vol 380. issue 1. 1997-06-06. PMID:9073087. |
in order to distinguish dopaminergic neurons from those using other catecholamines as the primary neurotransmitter, the distribution of dopamine-immunoreactive structures was compared to that of cell bodies, fibers, and terminals labelled with antibodies directed against the enzymes tyrosine hydroxylase (th), aromatic l-amino acid decarboxylase (aadc), dopamine beta-hydroxylase (dbh), and phenylethanolamine-n-methyl transferase (pnmt). |
1997-06-06 |
2023-08-12 |
Not clear |
| V I Mel'nikova, E V Proshliakova, A Ia Sapronova, M T Blue-Pazo, A Calas, M V Ugriumo. [The formation and regulation of the lactotrophic function of the hypophysis in the prenatal period of rat development. II. Dopamine inhibitory control of prolactin secretion]. Ontogenez. vol 28. issue 2. 1997-06-05. PMID:9173350. |
using the technique of radioimmunoassay, we studied the secretion of prolactin and its control by dopaminergic system in 22-day-old rat fetuses under normal conditions and after pharmacological inhibition of dopamine receptors. |
1997-06-05 |
2023-08-12 |
rat |
| J S Silvestre, M F O'Neill, A G Fernandez, J M Palacio. Effects of a range of dopamine receptor agonists and antagonists on ethanol intake in the rat. European journal of pharmacology. vol 318. issue 2-3. 1997-05-29. PMID:9016913. |
these results suggest the involvement of the dopaminergic system in ethanol intake and ethanol reinforcement with dopamine d1 and d2/d3 receptors playing opposing roles. |
1997-05-29 |
2023-08-12 |
rat |
| C Adelbrecht, Y Agid, R Raisman-Vozar. Effect of the weaver mutation on the expression of dopamine membrane transporter, tyrosine hydroxylase and vesicular monoamine transporter in dopaminergic neurons of the substantia nigra and the ventral tegmental area. Brain research. Molecular brain research. vol 43. issue 1-2. 1997-05-29. PMID:9037545. |
effect of the weaver mutation on the expression of dopamine membrane transporter, tyrosine hydroxylase and vesicular monoamine transporter in dopaminergic neurons of the substantia nigra and the ventral tegmental area. |
1997-05-29 |
2023-08-12 |
mouse |
| C Adelbrecht, Y Agid, R Raisman-Vozar. Effect of the weaver mutation on the expression of dopamine membrane transporter, tyrosine hydroxylase and vesicular monoamine transporter in dopaminergic neurons of the substantia nigra and the ventral tegmental area. Brain research. Molecular brain research. vol 43. issue 1-2. 1997-05-29. PMID:9037545. |
quantitative in situ hybridization of three different dopaminergic markers: dopamine membrane transporter (dat), tyrosine hydroxylase (th), and vesicular monoamine transporter (vmat2) was performed on individual dopaminergic cells of the substantia nigra pars compacta (snc) and the ventral tegmental area (vta) in 2-month-old wv/wv mice, in order to investigate the metabolic state of remaining dopaminergic cell bodies and gain further insight into modifications observed on dopaminergic nerve terminals in the striatum and the nucleus accumbens. |
1997-05-29 |
2023-08-12 |
mouse |
| T A Jenkins, S Y Chai, F A Mendelsoh. Upregulation of angiotensin II AT1 receptors in the mouse nucleus accumbens by chronic haloperidol treatment. Brain research. vol 748. issue 1-2. 1997-05-27. PMID:9067454. |
considering our previous anatomical and functional studies demonstrating an interaction between brain angiotensin ii and dopaminergic systems, the effect of chronic treatment with the dopamine antagonist, haloperidol, on at1 and at2 receptor levels was investigated in the mouse brain. |
1997-05-27 |
2023-08-12 |
mouse |
| H Cransac, L Peyrin, F Farhat, J M Cottet-Emard, J M Pequignot, A Rebe. Brain monoamines and optokinetic performances in pigmented and albino rats. Comparative biochemistry and physiology. Part A, Physiology. vol 116. issue 4. 1997-05-22. PMID:9125685. |
norepinephrine (ne), dopamine (da), serotonin (5-ht) and their metabolites were determined in retina, brainstem nuclei and dopaminergic areas. |
1997-05-22 |
2023-08-12 |
rat |
| C S Lee, H Sauer, A Bjorklun. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience. vol 72. issue 3. 1997-05-22. PMID:9157311. |
the results show that striatal 6-hydroxydopamine lesions produce dose-dependent decreases in striatal dopamine levels and tyrosine hydroxylase-immunoreactive cell numbers in the ipsilateral substantia nigra, accompanied by a significant long-lasting atrophy of the remaining dopaminergic neurons. |
1997-05-22 |
2023-08-12 |
rat |
| C S Lee, H Sauer, A Bjorklun. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience. vol 72. issue 3. 1997-05-22. PMID:9157311. |
paw reaching test scores on the side contralateral to the lesion were non-linearly correlated with dopaminergic neuronal cell loss and exhibited a clear symptomatic threshold such that impaired paw use appeared only after >50% loss of nigral dopamine neurons or a reduction of 60-80% of striatal dopamine levels. |
1997-05-22 |
2023-08-12 |
rat |
| C S Lee, H Sauer, A Bjorklun. Dopaminergic neuronal degeneration and motor impairments following axon terminal lesion by instrastriatal 6-hydroxydopamine in the rat. Neuroscience. vol 72. issue 3. 1997-05-22. PMID:9157311. |
the behavioral, cellular, and neurochemical effects of the nerve terminal lesion thus bear some resemblance to the early stages of parkinson's disease, where the severity of motor impairment is correlated with the loss of dopamine in the striatum and dopaminergic neuronal loss in the substantia nigra. |
1997-05-22 |
2023-08-12 |
rat |
| C G Goet. New strategies with dopaminergic drugs: modified formulations of levodopa and novel agonists. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126145. |
drugs that enhance dopaminergic function fall into three primary categories: amino acid precursors to dopamine, agonists that stimulate dopamine receptors, and enzyme antagonists that prevent the metabolism of dopamine and hence permit more or prolonged neurotransmitter activity; the first two are discussed below. |
1997-05-20 |
2023-08-12 |
Not clear |
| C G Goet. New strategies with dopaminergic drugs: modified formulations of levodopa and novel agonists. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126145. |
within the first category, levodopa is the amino acid precursor to dopamine, and a number of modifications in its formulation have been developed to enhance dopaminergic activity. |
1997-05-20 |
2023-08-12 |
Not clear |
| J H Kordower, C G Goetz, T B Freeman, C W Olano. Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126150. |
this paper describes the neuroanatomical correlates of dopamine brain grafting in humans and elucidates the pattern of changes seen in dopaminergic systems which are associated with clinical benefit. |
1997-05-20 |
2023-08-12 |
human |
| W J Bowers, D F Howard, H J Federof. Gene therapeutic strategies for neuroprotection: implications for Parkinson's disease. Experimental neurology. vol 144. issue 1. 1997-05-20. PMID:9126153. |
strategies to deliver genes include those that either augment dopamine biosynthesis or attenuate loss of dopaminergic neurons. |
1997-05-20 |
2023-08-12 |
Not clear |
| N Ginovart, A Lundin, L Farde, C Halldin, L Bäckman, C G Swahn, S Pauli, G Sedval. PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease. Brain : a journal of neurology. vol 120 ( Pt 3). 1997-05-16. PMID:9126061. |
we suggest that the finding reflects a loss of presynaptic terminals or a reduced expression of dopamine transporter in the nigrostriatal dopaminergic system in huntington's disease. |
1997-05-16 |
2023-08-12 |
Not clear |
| M Hamanoue, N Takemoto, K Matsumoto, T Nakamura, K Nakajima, S Kohsak. Neurotrophic effect of hepatocyte growth factor on central nervous system neurons in vitro. Journal of neuroscience research. vol 43. issue 5. 1997-05-15. PMID:8833090. |
moreover, the dopamine uptake into mesencephalic neurons was also enhanced by hgf treatment, indicating that hgf promotes the survival and/or maturation of mesencephalic dopaminergic neurons. |
1997-05-15 |
2023-08-12 |
rat |
| J B Zawilska, T Derbiszewska, J Z Nowa. Pharmacological modifications in dopaminergic neurotransmission affect the quinpirole-evoked suppression of serotonin N-acetyltransferase activity in chick retina: an impact on dopamine D4-like receptors. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 12. 1997-05-15. PMID:9029407. |
pharmacological modifications in dopaminergic neurotransmission affect the quinpirole-evoked suppression of serotonin n-acetyltransferase activity in chick retina: an impact on dopamine d4-like receptors. |
1997-05-15 |
2023-08-12 |
chicken |
| M Ruotsalainen, M Heikkilä, P Lillsunde, T Seppälä, L Ahte. Taurine infused intrastriatally elevates, but intranigrally decreases striatal extracellular dopamine concentration in anaesthetised rats. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 8-9. 1997-05-12. PMID:9013387. |
these results show that the effects of taurine on the concentrations of extracellular dopamine and its metabolites depend on its administration site on nigrostriatal dopaminergic neurons. |
1997-05-12 |
2023-08-12 |
rat |
| M Ruotsalainen, M Heikkilä, P Lillsunde, T Seppälä, L Ahte. Taurine infused intrastriatally elevates, but intranigrally decreases striatal extracellular dopamine concentration in anaesthetised rats. Journal of neural transmission (Vienna, Austria : 1996). vol 103. issue 8-9. 1997-05-12. PMID:9013387. |
it elevates the extracellular dopamine when given into the striatum, but when given into the cell body region of the nigrostriatal dopaminergic pathway it decreases the extracellular dopamine in the ipsilateral striatum. |
1997-05-12 |
2023-08-12 |
rat |
| J Fan. Hyperactive behavioural effects induced by intranigral infusion of a pyridinium metabolite of haloperidol in rats. Canadian journal of physiology and pharmacology. vol 74. issue 12. 1997-05-08. PMID:9047047. |
this apparent dopamine agonist effect of hp+ may be relevant to some of the clinical side effects of haloperidol such as acute dystonia and chronic tardive dyskinesia, which have been proposed to be the result of dopaminergic hyperactivity. |
1997-05-08 |
2023-08-12 |
rat |