| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R D Strous, N Bark, S S Parsia, J Volavka, H M Lachma. Analysis of a functional catechol-O-methyltransferase gene polymorphism in schizophrenia: evidence for association with aggressive and antisocial behavior. Psychiatry research. vol 69. issue 2-3. 1997-07-03. PMID:9109174. |
considering the role of comt in dopamine metabolism and the involvement of dopaminergic pathways in the pathogenesis of schizophrenia and violence, we screened 37 patients with schizophrenia to determine whether or not a behavioral association with the comt polymorphism exists. |
1997-07-03 |
2023-08-12 |
Not clear |
| S H Yen, C J Lai, J Y Lin, J T Pa. Inhibitory effect of dopamine on dorsomedial arcuate neurons in rat brain slices: potentiation by coadministration of cocaine. Brain research bulletin. vol 42. issue 5. 1997-07-01. PMID:9092875. |
whether dopamine (da) can have a direct effect on the tuberoinfundibular dopaminergic neurons has been a controversial issue. |
1997-07-01 |
2023-08-12 |
rat |
| J M Horowitz, J M DiPirro, M B Kristal, G Torre. Dopaminergic and glutamatergic mechanisms mediate the induction of FOS-like protein by cocaethylene. Brain research bulletin. vol 42. issue 5. 1997-07-01. PMID:9092881. |
administration of specific dopaminergic (sch-23390; 0.5 mg/kg) and glutamatergic (mk-801; 1 mg/kg) receptor antagonists prior to cocaethylene indicated a significant role for dopamine (d1) and n-methyl-d-aspartate receptor subtypes in mediating the nuclear induction of the aforementioned transcription factor protein. |
1997-07-01 |
2023-08-12 |
rat |
| T Araki, H Kato, K Shuto, T Fujiwara, Y Itoyam. Effect of aging on dopaminergic receptors and uptake sites in the rat brain studied by receptor autoradiography. Journal of the neurological sciences. vol 148. issue 2. 1997-06-30. PMID:9129108. |
furthermore, our results suggest that dopaminergic receptors and dopamine uptake sites may develop with different patterns and speeds after birth. |
1997-06-30 |
2023-08-12 |
rat |
| B Y Glenthøj, R Hemmingse. Dopaminergic sensitization: implications for the pathogenesis of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 21. issue 1. 1997-06-27. PMID:9075257. |
the authors have previously demonstrated, how it is possible to potentiate mesolimbic dopaminergic activity by intermittent electrical stimulations of the cells in the ventral tegmental area, and that influence on the central mesolimbic dopamine cells is essential for the strengthened neuroplastic response. |
1997-06-27 |
2023-08-12 |
Not clear |
| I C Wegner, R R Dawirs, C Grond, G Teuchert-Nood. Dopamine and the regulation of cell proliferation in gerbil (Meriones unguiculatus) pyloric mucosa. Life sciences. vol 60. issue 22. 1997-06-27. PMID:9180354. |
having demonstrated that dopaminergic cells occur in the stomach of gerbils (meriones unguiculatus), in the present study we examined the influence of dopamine antagonist haloperidol on the proliferation of epithelial cells in the mucosa of the stomach. |
1997-06-27 |
2023-08-12 |
Not clear |
| M C Ritz, F R Georg. Cocaine toxicity: concurrent influence of dopaminergic, muscarinic and sigma receptors in mediating cocaine-induced lethality. Psychopharmacology. vol 129. issue 4. 1997-06-19. PMID:9085400. |
the dopamine reuptake inhibitor bupropion increased the number of occurrences of lethality produced by (-) cocaine, while the dopaminergic d1 antagonist sch 23390, the muscarinic m1 antagonist pirenzepine, and the sigma ligand (+) skf 10047 all significantly, but only partially, antagonized (-) cocaine-induced lethality. |
1997-06-19 |
2023-08-12 |
mouse |
| W J Chen, S E Maier, J R Wes. Prenatal alcohol treatment attenuated postnatal cocaine-induced elevation of dopamine concentration in nucleus accumbens: a preliminary study. Neurotoxicology and teratology. vol 19. issue 1. 1997-06-19. PMID:9088009. |
the present study investigated one of the functional aspects of dopaminergic system in neonatal rats exposed prenatally to a binge-like alcohol paradigm by measuring dopamine concentrations following a single postnatal cocaine challenge. |
1997-06-19 |
2023-08-12 |
rat |
| W J Chen, S E Maier, J R Wes. Prenatal alcohol treatment attenuated postnatal cocaine-induced elevation of dopamine concentration in nucleus accumbens: a preliminary study. Neurotoxicology and teratology. vol 19. issue 1. 1997-06-19. PMID:9088009. |
taken together, these results indicate that there appears to be a regional difference in acute cocaine-induced dopamine elevation, and prenatal binge-like alcohol exposure significantly alters the functional responsiveness of dopaminergic system in nac. |
1997-06-19 |
2023-08-12 |
rat |
| S Jordan, J L Eberling, K S Bankiewicz, D Rosenberg, P G Coxson, H F VanBrocklin, J P O'Neil, M E Emborg, W J Jagus. 6-[18F]fluoro-L-m-tyrosine: metabolism, positron emission tomography kinetics, and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine lesions in primates. Brain research. vol 750. issue 1-2. 1997-06-17. PMID:9098552. |
fpac was most concentrated in dopaminergic areas whereas lower levels occurred in areas containing few dopamine terminals. |
1997-06-17 |
2023-08-12 |
monkey |
| S K Schlachter, T J Poel, C F Lawson, D M Dinh, M E Lajiness, A G Romero, S A Rees, J N Duncan, M W Smit. Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D4 receptor. European journal of pharmacology. vol 322. issue 2-3. 1997-06-16. PMID:9098699. |
they exhibited at least 100-fold lower affinities for dopamine d2 and for other dopaminergic, serotonergic and adrenergic receptors. |
1997-06-16 |
2023-08-12 |
human |
| S Dukic, S Kostic-Rajacic, V Soskic, J Joksimovi. Synthesis and dopaminergic properties of 3- and 4-substituted 1-[2-[5-(1H-benzimidazole-2-thione)]ethyl]piperidines and related compounds. Archiv der Pharmazie. vol 330. issue 1-2. 1997-06-16. PMID:9112811. |
with an aim of creating new, high affinity dopaminergic ligands, six different 3- and 4-substituted 1-[2-[5-(1h-benzimidazole-2-thione)] ethyl]piperidines and nine related heterocyclic congeners were synthesized and evaluated for in vitro binding affinity at d1 and d2 dopamine receptors. |
1997-06-16 |
2023-08-12 |
cattle |
| M Strittmatter, M Grauer, E Isenberg, G Hamann, C Fischer, K H Hoffmann, F Blaes, K Schimrig. Cerebrospinal fluid neuropeptides and monoaminergic transmitters in patients with trigeminal neuralgia. Headache. vol 37. issue 4. 1997-06-16. PMID:9150615. |
as a marker for the dopaminergic system, we determined cerebrospinal fluid concentrations of dopamine and its metabolite, homovanillic acid. |
1997-06-16 |
2023-08-12 |
Not clear |
| M Maitr. The gamma-hydroxybutyrate signalling system in brain: organization and functional implications. Progress in neurobiology. vol 51. issue 3. 1997-06-13. PMID:9089792. |
stimulation of these receptors with low amounts of gamma-hydroxybutyrate induces in general hyperpolarizations in dopaminergic structures with a reduction of dopamine release. |
1997-06-13 |
2023-08-12 |
rat |
| T Nagatsu, H Ichinos. GTP cyclohydrolase I gene, tetrahydrobiopterin, and tyrosine hydroxylase gene: their relations to dystonia and parkinsonism. Neurochemical research. vol 21. issue 2. 1997-06-12. PMID:9182249. |
when gch activity is decreased to less than 20% of the normal value, the activity of th in the nigrostriatal dopaminergic neurons may be first decreased resulting in decreases in th activity and dopamine level, and in the symptoms of hpd/drd. |
1997-06-12 |
2023-08-12 |
human |
| M M Robertson, J S Ster. The Gilles de la Tourette syndrome. Critical reviews in neurobiology. vol 11. issue 1. 1997-06-10. PMID:9093811. |
management is with a combination of psychosocial measures and drugs; in particular dopamine antagonists, the efficacy of which has led to the theory that the syndrome is caused by an abnormality of the dopaminergic system. |
1997-06-10 |
2023-08-12 |
Not clear |
| M J Nirenberg, J Chan, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 11. 1997-06-10. PMID:9151720. |
the dopamine transporter (dat) plays an important role in the plasmalemmal reuptake of dopamine and, thus, in the termination of normal dopaminergic neurotransmission. |
1997-06-10 |
2023-08-12 |
rat |
| M J Nirenberg, J Chan, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 11. 1997-06-10. PMID:9151720. |
dat is also a major binding site for cocaine and other stimulants, the psychoactive effects of which are associated primarily with the inhibition of dopamine reuptake within mesocorticolimbic dopaminergic neurons. |
1997-06-10 |
2023-08-12 |
rat |
| M J Nirenberg, J Chan, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 11. 1997-06-10. PMID:9151720. |
these findings suggest that intermediate and distal dendrites are both the primary sites of dopamine reuptake and the principal targets of cocaine and related psychostimulants within dopaminergic neurons in the vta. |
1997-06-10 |
2023-08-12 |
rat |
| P K Andrus, T J Fleck, J A Oostveen, E D Hal. Neuroprotective effects of the novel brain-penetrating pyrrolopyrimidine antioxidants U-101033E and U-104067F against post-ischemic degeneration of nigrostriatal neurons. Journal of neuroscience research. vol 47. issue 6. 1997-06-09. PMID:9089214. |
the results show that both the pyrrolopyrimidines (u-101033e and u-104067f) significantly attenuate the postischemic loss of ns dopaminergic neurons and further support the involvement of a dopamine metabolism-derived, oxygen radical-induced lipid peroxidative mechanism. |
1997-06-09 |
2023-08-12 |
Not clear |