| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Qian, Y Wu, H Yang, A C Michae. An integrated decoupler for capillary electrophoresis with electrochemical detection: application to analysis of brain microdialysate. Analytical chemistry. vol 71. issue 20. 1999-11-30. PMID:10546530. |
the dopamine concentration in 1-min brain microdialysis samples was significantly altered by drug treatments and by brief electrical stimulation of dopaminergic axons. |
1999-11-30 |
2023-08-12 |
rat |
| D Dassesse, J M Vanderwinden, I Goldberg, J J Vanderhaeghen, S N Schiffman. Caffeine-mediated induction of c-fos, zif-268 and arc expression through A1 receptors in the striatum: different interactions with the dopaminergic system. The European journal of neuroscience. vol 11. issue 9. 1999-11-24. PMID:10510174. |
the involvement of dopamine systems was evaluated by manipulations of the dopaminergic transmission. |
1999-11-24 |
2023-08-12 |
Not clear |
| M S Szczypka, M A Rainey, D S Kim, W A Alaynick, B T Marck, A M Matsumoto, R D Palmite. Feeding behavior in dopamine-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 96. issue 21. 1999-11-24. PMID:10518589. |
mice that cannot make dopamine (da), a condition caused by the selective inactivation of tyrosine hydroxylase in dopaminergic neurons, are born normal but gradually become hypoactive and hypophagic, and die at 3 weeks of age. |
1999-11-24 |
2023-08-12 |
mouse |
| A D Sperfeld, M B Collatz, H Baier, M Palmbach, A Storch, J Schwarz, K Tatsch, S Reske, M Joosse, P Heutink, A C Ludolp. FTDP-17: an early-onset phenotype with parkinsonism and epileptic seizures caused by a novel mutation. Annals of neurology. vol 46. issue 5. 1999-11-24. PMID:10553987. |
we define the dopaminergic deficits as being predominantly presynaptic by the use of single-photon emission computed tomography with a dopamine transporter ligand. |
1999-11-24 |
2023-08-12 |
Not clear |
| Y Ouchi, T Kanno, H Okada, E Yoshikawa, M Futatsubashi, S Nobezawa, T Torizuka, M Sakamot. Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study. Annals of neurology. vol 46. issue 5. 1999-11-24. PMID:10553989. |
to investigate changes in the relation between presynaptic and postsynaptic dopaminergic functions in vivo in both nigrostriatal and mesocortical systems in parkinson's disease (pd), 10 drug-naive early pd patients were studied twice using positron emission tomography with [11c]cft (dopamine transporter probe) followed by [11c]sch 23390 (d1 receptor probe). |
1999-11-24 |
2023-08-12 |
Not clear |
| F Amenta, E Bronzetti, L Felici, A Ricci, S K Tayebat. Dopamine D2-like receptors on human peripheral blood lymphocytes: a radioligand binding assay and immunocytochemical study. Journal of autonomic pharmacology. vol 19. issue 3. 1999-11-22. PMID:10511471. |
the standardisation of immunocytochemical techniques for detecting human peripheral blood lymphocyte dopamine receptors may contribute to clarify their role in lymphocyte function or as a peripheral marker of the status of the dopaminergic system. |
1999-11-22 |
2023-08-12 |
human |
| R Betarbet, J T Greenamyr. Differential expression of glutamate receptors by the dopaminergic neurons of the primate striatum. Experimental neurology. vol 159. issue 2. 1999-11-19. PMID:10506511. |
we speculate that glutamate may play a role in regulating the number of these dopaminergic neurons after mptp treatment and may also influence their ability to release dopamine. |
1999-11-19 |
2023-08-12 |
Not clear |
| G T Liberatore, D I Finkelstein, J Y Wong, M K Horne, M J Porritt, G A Donnan, D W Howell. Sprouting of dopaminergic axons after striatal injury: confirmation by markers not dependent on dopamine metabolism. Experimental neurology. vol 159. issue 2. 1999-11-19. PMID:10506529. |
sprouting of dopaminergic axons after striatal injury: confirmation by markers not dependent on dopamine metabolism. |
1999-11-19 |
2023-08-12 |
mouse |
| G T Liberatore, D I Finkelstein, J Y Wong, M K Horne, M J Porritt, G A Donnan, D W Howell. Sprouting of dopaminergic axons after striatal injury: confirmation by markers not dependent on dopamine metabolism. Experimental neurology. vol 159. issue 2. 1999-11-19. PMID:10506529. |
however, by examining axons and their branches using markers that are independent of dopamine metabolism it is possible to determine whether dopaminergic sprouting does in fact take place. |
1999-11-19 |
2023-08-12 |
mouse |
| A M Li. Recovery by NO of the iron-attenuated dopamine dynamics in nigrostriatal system of rat brain. Neuroscience research. vol 34. issue 3. 1999-11-10. PMID:10515255. |
taken together, our in vivo electrochemical study suggests that nitric oxide does not alter dopamine dynamics in nigrostriatal dopaminergic system. |
1999-11-10 |
2023-08-12 |
rat |
| K K Midha, J W Hubbard, G McKay, M J Rawson, D Hsi. The role of metabolites in a bioequivalence study II: amoxapine, 7-hydroxyamoxapine, and 8-hydroxyamoxapine. International journal of clinical pharmacology and therapeutics. vol 37. issue 9. 1999-11-05. PMID:10507241. |
in animals, amoxapine blocks the reuptake of norepinephrine and, to a lesser extent serotonin, into their respective neurons and blocks the response of dopaminergic receptors to dopamine. |
1999-11-05 |
2023-08-12 |
Not clear |
| A Storch, A C Ludolph, J Schwar. HEK-293 cells expressing the human dopamine transporter are susceptible to low concentrations of 1-methyl-4-phenylpyridine (MPP+) via impairment of energy metabolism. Neurochemistry international. vol 35. issue 5. 1999-11-02. PMID:10517700. |
selective dopaminergic neurotoxicity induced by 1-methyl-4-phenylpyridine (mpp+) is believed to be due to the transmembrane uptake by the dopamine transporter and subsequent inhibition of mitochondrial complex i and/or production of free radicals. |
1999-11-02 |
2023-08-12 |
human |
| O Kuche. Peripheral dopamine in hypertension and associated conditions. Journal of human hypertension. vol 13. issue 9. 1999-11-01. PMID:10482970. |
in conclusion dopamine should thus be monitored in hypertension while respecting several associated conditions affecting peripheral dopaminergic activity. |
1999-11-01 |
2023-08-12 |
Not clear |
| R Sandy. AC pulsed electromagnetic fields-induced sexual arousal and penile erections in Parkinson's disease. The International journal of neuroscience. vol 99. issue 1-4. 1999-10-28. PMID:10495212. |
it has been suggested that the therapeutic efficacy of transcranial administration of ac pulsed electromagnetic fields (emfs) in the picotesla flux density in pd involves the activation of dopamine d2 receptor sites which are the principal site of action of dopaminergic pharmacotherapy in pd. |
1999-10-28 |
2023-08-12 |
Not clear |
| Y Fang, O K Ronneklei. Cocaine upregulates the dopamine transporter in fetal rhesus monkey brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 20. 1999-10-28. PMID:10516315. |
cocaine is a highly addictive drug that binds to the dopamine transporter (dat), inhibits the reuptake of dopamine, and initiates multiple actions within midbrain dopaminergic systems. |
1999-10-28 |
2023-08-12 |
human |
| A M Kang, M A Palmatier, K K Kid. Global variation of a 40-bp VNTR in the 3'-untranslated region of the dopamine transporter gene (SLC6A3). Biological psychiatry. vol 46. issue 2. 1999-10-25. PMID:10418689. |
the dopamine transporter (dat) is the primary mechanism for dopamine clearance from the synapse in midbrain dopaminergic neurons, and the target of psychostimulant and neurotoxic drugs such as cocaine, amphetamine, and mptp. |
1999-10-25 |
2023-08-12 |
Not clear |
| Z L Rossetti, D Isola, J De Vry, F Fadd. Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471090. |
to assess the role of l-type calcium channels in the inhibition of the dopaminergic system in the withdrawal state, the effects of the dihydropyridine calcium channel antagonist nimodipine on the extracellular levels of dopamine were studied in the nucleus accumbens shell of awake rats 10 h after withdrawal from chronic ethanol intoxication. |
1999-10-25 |
2023-08-12 |
rat |
| R M Kostrzewa, R Brus, K W Perr. Interactive modulation by dopamine and serotonin neurons of receptor sensitivity of the alternate neurochemical system. Polish journal of pharmacology. vol 51. issue 1. 1999-10-21. PMID:10389143. |
ontogenetic dopaminergic denervation of rat forebrain is associated with latent supersensitization of dopamine (da) receptors that is unmasked only by a priming process entailing repeated da agonist treatments. |
1999-10-21 |
2023-08-12 |
human |
| M Garzón, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter. The Journal of comparative neurology. vol 410. issue 2. 1999-10-21. PMID:10414527. |
these dopaminergic neurons differentially project to cortical and limbic forebrain regions, where their terminals differ in levels of expression of the plasmalemmal dopamine transporter (dat). |
1999-10-21 |
2023-08-12 |
rat |
| M Garzón, R A Vaughan, G R Uhl, M J Kuhar, V M Picke. Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter. The Journal of comparative neurology. vol 410. issue 2. 1999-10-21. PMID:10414527. |
these results suggest selective targeting of cholinergic afferents in the vta to non-dopaminergic neurons and a subpopulation of dopaminergic neurons that have a limited capacity for plasmalemmal reuptake of dopamine, a characteristic of those that project to the frontal cortex. |
1999-10-21 |
2023-08-12 |
rat |