| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| John G Partridge, Subbu Apparsundaram, Greg A Gerhardt, Jennifer Ronesi, David M Lovinge. Nicotinic acetylcholine receptors interact with dopamine in induction of striatal long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923419. |
dopamine release is modulated by activation of nicotinic receptors in the dorsal striatum, and activation of nicotinic receptors during high-frequency synaptic activation appears to be capable of interacting with dopaminergic actions that lead to striatal ltd. our results suggest that stimulation of mechanisms involved in striatal synaptic plasticity is an important role for striatal nicotinic acetylcholine receptors and that these mechanisms may contribute to the enhancement of learning and habit formation produced by nicotine intake. |
2002-04-08 |
2023-08-12 |
Not clear |
| James Bilsland, Sophie Roy, Steve Xanthoudakis, Donald W Nicholson, Yongxin Han, Erich Grimm, Franz Hefti, Sarah J Harpe. Caspase inhibitors attenuate 1-methyl-4-phenylpyridinium toxicity in primary cultures of mesencephalic dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923429. |
in primary cultures of rat mesencephalic dopaminergic neurons, mpp+ treatment decreased the number of surviving dopaminergic neurons in the cultures and the ability of the neurons to take up [3h]dopamine ([3h]da). |
2002-04-08 |
2023-08-12 |
rat |
| Candice Drouin, Laurent Darracq, Fabrice Trovero, Gérard Blanc, Jacques Glowinski, Susanna Cotecchia, Jean-Pol Tassi. Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 7. 2002-04-08. PMID:11923452. |
because catecholamine tissue levels, autoradiography of d1 and d2 dopaminergic receptors, and of dopamine reuptake sites and locomotor response to a d1 agonist showed that basal dopaminergic transmission was similar in knock-out and wild-type mice, our data indicate a critical role of alpha1b-adrenergic receptors and noradrenergic transmission in the vulnerability to addiction. |
2002-04-08 |
2023-08-12 |
mouse |
| José L Bata-García, Francisco J Heredia-López, Fernando J Alvarez-Cervera, Gloria Arankowsky-Sandoval, José L Góngora-Alfar. Circling behavior induced by microinjection of serotonin reuptake inhibitors in the substantia nigra. Pharmacology, biochemistry, and behavior. vol 71. issue 1-2. 2002-04-05. PMID:11812544. |
since current theories of circling behavior hypothesize that the animal turns away from the cerebral hemisphere where dopamine neurotransmission predominates, these results suggest that the contraversive circling induced by the unilateral microinjection of sris into the snc could be mediated by a 5-ht-induced increase of firing frequency of nigrostriatal dopaminergic neurons. |
2002-04-05 |
2023-08-12 |
rat |
| Sophie Callier, Maryvonne Le Saux, Anne-Marie Lhiaubet, Thérèse Di Paolo, William Rostène, Didier Pelapra. Evaluation of the protective effect of oestradiol against toxicity induced by 6-hydroxydopamine and 1-methyl-4-phenylpyridinium ion (Mpp+) towards dopaminergic mesencephalic neurones in primary culture. Journal of neurochemistry. vol 80. issue 2. 2002-04-04. PMID:11902121. |
the efficiency of both toxins and oestradiol was evaluated by tyrosine hydroxylase (th) immunocytochemistry, [3h]dopamine ([3h]da) uptake, length of dopaminergic processes and lactate dehydrogenase (ldh) release measurement. |
2002-04-04 |
2023-08-12 |
Not clear |
| Stéphanie Barc, Guylène Page, Laurence Barrier, Lucette Garreau, Denis Guilloteau, Bernard Fauconneau, Sylvie Chalo. Relevance of different striatal markers in assessment of the MPP+-induced dopaminergic nigrostriatal injury in rat. Journal of neurochemistry. vol 80. issue 3. 2002-04-04. PMID:11905985. |
the in vivo binding of (e)-n-(3-iodoprop-2-enyl)-2-beta-carbomethoxy-3beta-(4'-methylphenyl)nortropane (pe2i), a selective and potent inhibitor of the neuronal dopamine transporter (dat) was considered as the reference index of injury of striatal dopaminergic nerve-endings. |
2002-04-04 |
2023-08-12 |
rat |
| M P Curran, C M Perr. Amisulpride: a review of its use in the management of schizophrenia. Drugs. vol 61. issue 14. 2002-04-02. PMID:11735643. |
at low doses, it enhances dopaminergic neurotransmission by preferentially blocking presynaptic dopamine d2/d3 autoreceptors. |
2002-04-02 |
2023-08-12 |
Not clear |
| M P Curran, C M Perr. Amisulpride: a review of its use in the management of schizophrenia. Drugs. vol 61. issue 14. 2002-04-02. PMID:11735643. |
at higher doses, amisupride antagonises postsynaptic dopamine d2 and d3 receptors, preferentially in the limbic system rather than the striatum, thereby reducing dopaminergic transmission. |
2002-04-02 |
2023-08-12 |
Not clear |
| Paolo S D'Aquila, Alessandra T Peana, Olga Tanda, Gino Serr. Different sensitivity to the motor-stimulating effect of amphetamine in Sardinian alcohol-preferring and non-preferring rats. European journal of pharmacology. vol 435. issue 1. 2002-04-02. PMID:11790379. |
the present results might be explained by the previously reported reduced density of dopamine receptors in the nucleus accumbens of sp rats and are consistent with the view that alcohol preference is associated with a deficient dopaminergic transmission. |
2002-04-02 |
2023-08-12 |
rat |
| Christina A Schad, Joseph B Justice, Stephen G Holtzma. Endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions. The Journal of pharmacology and experimental therapeutics. vol 300. issue 3. 2002-03-28. PMID:11861800. |
endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions. |
2002-03-28 |
2023-08-12 |
rat |
| Anna Mattsson, Sven Ove Ogren, Lars Olso. Facilitation of dopamine-mediated locomotor activity in adult rats following cholinergic denervation. Experimental neurology. vol 174. issue 1. 2002-03-28. PMID:11869038. |
the dopamine hypothesis of schizophrenia postulates hyperactivity of dopaminergic neurotransmission in the mesolimbic system. |
2002-03-28 |
2023-08-12 |
rat |
| Y Maruyama, Y Suzuki, A Kazusaka, S Fujit. Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells via dopamine transporter. Archives of toxicology. vol 75. issue 4. 2002-03-27. PMID:11482518. |
uptake of the dopaminergic neurotoxin, norsalsolinol, into pc12 cells via dopamine transporter. |
2002-03-27 |
2023-08-12 |
Not clear |
| Patrice Congar, Annie Bergevin, Louis-Eric Trudea. D2 receptors inhibit the secretory process downstream from calcium influx in dopaminergic neurons: implication of K+ channels. Journal of neurophysiology. vol 87. issue 2. 2002-03-26. PMID:11826068. |
dopaminergic (daergic) neurons possess d2-like somatodendritic and terminal autoreceptors that modulate cellular excitability and dopamine (da) release. |
2002-03-26 |
2023-08-12 |
Not clear |
| Thomas Wichmann, Michele A Kliem, Jesus Soare. Slow oscillatory discharge in the primate basal ganglia. Journal of neurophysiology. vol 87. issue 2. 2002-03-26. PMID:11826081. |
oscillations with periods in the multisecond range have previously been recorded in basal ganglia neurons of awake paralyzed rats, and in these animals were shown to be increased by systemic dopaminergic stimulation, but not altered by depletion of the nigrostriatal dopamine supply. |
2002-03-26 |
2023-08-12 |
rat |
| Elisa Mengual, Virginia M Picke. Ultrastructural immunocytochemical localization of the dopamine D2 receptor and tyrosine hydroxylase in the rat ventral pallidum. Synapse (New York, N.Y.). vol 43. issue 3. 2002-03-21. PMID:11793420. |
they also suggest that in this region the presynaptic d2 receptors are 1) minimally involved in autoregulation of dopaminergic transmission, and 2) differentially activated by dopamine, depending in part on levels and distance from release sites. |
2002-03-21 |
2023-08-12 |
rat |
| K Shimizu, M Watanabe, Y Kodama, Y Hagino, T Ogasawara, S Nomur. [Effect of ATP-sensitive K+ channel blocker (quinine) on the dopamine decrease induced by selective D3 agonist (7-OH-DPAT) in the rat striatum]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 21. issue 5. 2002-03-18. PMID:11797417. |
therefore these results suggest that katp channels may be present in nigrostriatal dopaminergic terminals and that in the striatum, presynaptic dopamine d3 autoreceptors and/or a post-synaptic d3 related short-loop negative feedback system inhibit dopamine release tonically by the activation of katp channels. |
2002-03-18 |
2023-08-12 |
rat |
| F Magnifico, G Pierangeli, G Barletta, C Candela, G Bonavina, M Contin, P Cortell. The cardiovascular effects of metoclopramide in multiple system atrophy and pure autonomic failure. Clinical autonomic research : official journal of the Clinical Autonomic Research Society. vol 11. issue 3. 2002-03-14. PMID:11605821. |
metoclopramide (mcp), a central and peripheral dopaminergic blocker with cholinergic activity, has been proposed to treat orthostatic hypotension (oh) on the basis that it could antagonize the vasodilator and natriuretic effects of dopamine. |
2002-03-14 |
2023-08-12 |
human |
| T Nakahara, T Yamamoto, K Endo, H Kayam. Neuronal ectopic expression of tyrosine hydroxylase in the mouse striatum by combined administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 3-nitropropionic acid. Neuroscience. vol 108. issue 4. 2002-03-14. PMID:11738497. |
these neurons were also immunoreactive to aromatic l-amino acid decarboxylase.we conclude that the combined administration of mptp and 3-npa caused a more profound damage to the nigro-striatal dopaminergic system, and thus some striatal neurons capable of up-regulating tyrosine hydroxylase were induced to produce dopamine, probably to compensate for the dopamine depletion. |
2002-03-14 |
2023-08-12 |
mouse |
| F Giuliano, J Allar. Dopamine and male sexual function. European urology. vol 40. issue 6. 2002-03-14. PMID:11805404. |
specific tests allowing assessment of sexual motivation showed that the release of dopamine at the level of the nucleus accumbens (innervated by the mesolimbic dopaminergic pathway) and the medial preoptic area of the hypothalamus (innervated by the dopaminergic incertohypothalamic pathway) positively regulated the anticipatory/motivational phase of copulatory behavior. |
2002-03-14 |
2023-08-12 |
rat |
| F Giuliano, J Allar. Dopamine and male sexual function. European urology. vol 40. issue 6. 2002-03-14. PMID:11805404. |
it is noteworthy that these participations of the dopaminergic system are not specific for sexual behavior but rather reflect the involvement of dopamine in the regulation of cognitive, integrative and reward processes. |
2002-03-14 |
2023-08-12 |
rat |