| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher H van Dyck, John P Seibyl, Robert T Malison, Marc Laruelle, Sami S Zoghbi, Ronald M Baldwin, Robert B Inni. Age-related decline in dopamine transporters: analysis of striatal subregions, nonlinear effects, and hemispheric asymmetries. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 10. issue 1. 2002-02-06. PMID:11790633. |
neuroimaging studies have documented an age-related decline in striatal dopamine transporters (dats) as a marker of dopaminergic neurodegeneration. |
2002-02-06 |
2023-08-12 |
human |
| F J Jiménez-Jiménez, P J García-Rui. Pharmacological options for the treatment of Tourette's disorder. Drugs. vol 61. issue 15. 2002-02-05. PMID:11772131. |
the potential usefulness of atypical antipsychotic drugs (risperidone, olanzapine, clozapine, ziprasidone) and other dopaminergic drugs (fluphenazine, sulpiride, tiapride, metoclopramide, piquindone, tetrabenazine), clonazepam, calcium channel antagonists, botulinum toxin, dopamine agonists, selegiline, and other drugs is discussed. |
2002-02-05 |
2023-08-12 |
Not clear |
| P J Blanchet, F Calon, M Morissette, M Goulet, R Grondin, D Lévesque, P J Bédard, T Di Paol. Regulation of dopamine receptors and motor behavior following pulsatile and continuous dopaminergic replacement strategies in the MPTP primate model. Advances in neurology. vol 86. 2002-02-04. PMID:11553994. |
regulation of dopamine receptors and motor behavior following pulsatile and continuous dopaminergic replacement strategies in the mptp primate model. |
2002-02-04 |
2023-08-12 |
Not clear |
| Dean E Dluzen, Linda I Anderson, Janet L McDermott, Jan Kucera, Jon M Walr. Striatal dopamine output is compromised within +/- BDNF mice. Synapse (New York, N.Y.). vol 43. issue 2. 2002-02-01. PMID:11754489. |
we reported previously that mice lacking one brain-derived neurotrophic factor (bdnf) allele demonstrate elevated striatal dopamine (da) concentrations but impaired behavioral responses involving the nigrostriatal dopaminergic (nsda) system. |
2002-02-01 |
2023-08-12 |
mouse |
| M B O'Byrne, J P Bolam, J J Hanley, K F Tipto. Tyrosine-hydroxylase immunoreactive cells in the rat striatum following treatment with MPP+. Advances in experimental medicine and biology. vol 483. 2002-01-29. PMID:11787621. |
tyrosine hydroxylase is the rate-limiting enzyme in the synthesis of dopamine, and as such, it is widely used as a marker of dopaminergic cells. |
2002-01-29 |
2023-08-12 |
rat |
| R S Scroggs, C G Cardenas, J A Whittaker, S T Kita. Muscarine reduces calcium-dependent electrical activity in substantia nigra dopaminergic neurons. Journal of neurophysiology. vol 86. issue 6. 2002-01-28. PMID:11731553. |
the reduction of the sahp via activation of muscarinic receptors in vivo may provide a mechanism whereby cholinergic inputs to da neurons from the tegmental peduncular pontine nucleus could modulate dopamine release at dopaminergic targets in the brain. |
2002-01-28 |
2023-08-12 |
rat |
| M Levite, Y Chowers, Y Ganor, M Besser, R Hershkovits, L Cahalo. Dopamine interacts directly with its D3 and D2 receptors on normal human T cells, and activates beta1 integrin function. European journal of immunology. vol 31. issue 12. 2002-01-24. PMID:11745370. |
we show here that dopamine interacts directly with dopaminergic receptors on normal human t cells and triggers beta1 integrin-mediated t cell adhesion to a major extracellular matrix component, fibronectin (fn). |
2002-01-24 |
2023-08-12 |
human |
| Candice Drouin, Gérard Blanc, Anne-Sophie Villégier, Jacques Glowinski, Jean-Pol Tassi. Critical role of alpha1-adrenergic receptors in acute and sensitized locomotor effects of D-amphetamine, cocaine, and GBR 12783: influence of preexposure conditions and pharmacological characteristics. Synapse (New York, N.Y.). vol 43. issue 1. 2002-01-24. PMID:11746733. |
this possibility was tested on locomotor responses induced either by d-amphetamine and cocaine, which both interfere with noradrenergic and dopaminergic transmissions, or by gbr 12783, a specific dopamine reuptake inhibitor. |
2002-01-24 |
2023-08-12 |
rat |
| L F López-Santiago, J C Gómora, G Cot. Postnatal decrease of sodium current density in rat pituitary melanotropes following the onset of dopaminergic innervation. Neuroscience letters. vol 315. issue 3. 2002-01-23. PMID:11716982. |
peptide secretion from rat melanotropes is tonically inhibited by a dopaminergic synaptic input that develops after birth and acts through d2 dopamine receptors. |
2002-01-23 |
2023-08-12 |
rat |
| S K Michelhaugh, C Fiskerstrand, E Lovejoy, M J Bannon, J P Quin. The dopamine transporter gene (SLC6A3) variable number of tandem repeats domain enhances transcription in dopamine neurons. Journal of neurochemistry. vol 79. issue 5. 2002-01-17. PMID:11739616. |
this study demonstrates by lipid transfection into an immortalized dopaminergic cell line and biolistic transfection into dopamine neurons in neonatal rat midbrain slices that the human nine-repeat dat vntr can enhance transcription. |
2002-01-17 |
2023-08-12 |
human |
| M Preece, B Mukherjee, C L Huang, L D Hall, R A Leslie, M F Jame. Detection of pharmacologically mediated changes in cerebral activity by functional magnetic resonance imaging: the effects of sulpiride in the brain of the anaesthetised rat. Brain research. vol 916. issue 1-2. 2002-01-14. PMID:11597597. |
these data are supportive of the notion that sulpiride causes an increase in frontal dopaminergic function by antagonism of presynaptically located dopamine d(2) receptors in this brain region, consistent with its therapeutic action. |
2002-01-14 |
2023-08-12 |
rat |
| F M Zhou, Y Liang, J A Dan. Endogenous nicotinic cholinergic activity regulates dopamine release in the striatum. Nature neuroscience. vol 4. issue 12. 2002-01-11. PMID:11713470. |
here we show that the precise overlap of striatal dopaminergic and cholinergic fibers underlies potent control of dopamine release by ongoing nicotinic receptor activity. |
2002-01-11 |
2023-08-12 |
mouse |
| K P Datla, M Christidou, W W Widmer, H K Rooprai, D T Dexte. Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease. Neuroreport. vol 12. issue 17. 2002-01-11. PMID:11726811. |
unilateral infusion of the dopaminergic neurotoxin, 6-hydroxydopamine (6-ohda; 8 microg), onto medial forebrain bundle significantly reduced the number of tyrosine hydroxylase positive (th+) cells in the substantia nigra and decreased striatal dopamine content in the vehicle treated rats. |
2002-01-11 |
2023-08-12 |
rat |
| H Tsukada, N Harada, H Ohba, S Nishiyama, T Kakiuch. Facilitation of dopaminergic neural transmission does not affect [(11)C]SCH23390 binding to the striatal D(1) dopamine receptors, but the facilitation enhances phosphodiesterase type-IV activity through D(1) receptors: PET studies in the conscious monkey brain. Synapse (New York, N.Y.). vol 42. issue 4. 2002-01-10. PMID:11746724. |
facilitation of dopaminergic neural transmission does not affect [(11)c]sch23390 binding to the striatal d(1) dopamine receptors, but the facilitation enhances phosphodiesterase type-iv activity through d(1) receptors: pet studies in the conscious monkey brain. |
2002-01-10 |
2023-08-12 |
monkey |
| C Deransart, G B Landwehrmeyer, T J Feuerstein, C H Lückin. Up-regulation of D3 dopaminergic receptor mRNA in the core of the nucleus accumbens accompanies the development of seizures in a genetic model of absence-epilepsy in the rat. Brain research. Molecular brain research. vol 94. issue 1-2. 2002-01-03. PMID:11597777. |
when compared to non-epileptic control rats, epileptic rats displayed no change in the expression of mrnas coding for the neuronal dopaminergic markers (tyrosine hydroxylase, membraneous and vesicular dopamine transporters). |
2002-01-03 |
2023-08-12 |
rat |
| L Voruganti, P Slomka, P Zabel, G Costa, A So, A Mattar, A G Awa. Subjective effects of AMPT-induced dopamine depletion in schizophrenia: correlation between dysphoric responses and striatal D(2) binding ratios on SPECT imaging. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 5. 2002-01-03. PMID:11682247. |
these results support the notion that striatal dopaminergic activity is not uniformly elevated in all schizophrenic patients, and the sub-group of individuals with lower baseline dopamine function are at an increased risk for dysphoric responses during antipsychotic therapy with dopaminergic blocking drugs. |
2002-01-03 |
2023-08-12 |
Not clear |
| T Sato, M M Meguid, S O Fetissov, C Chen, L Zhan. Hypothalamic dopaminergic receptor expressions in anorexia of tumor-bearing rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 281. issue 6. 2002-01-02. PMID:11705777. |
our past microdialysis studies in ventromedial hypothalamic nucleus (vmn) and lateral hypothalamic area (lha) of changes in dopamine concentrations in response to changes in food intake [characterized as feeding pattern (changes in meal number and size)] in anorexia of cancer show abnormal presynaptic dopaminergic neurotransmission. |
2002-01-02 |
2023-08-12 |
rat |
| T Nakamura, V Dhawan, T Chaly, M Fukuda, Y Ma, R Breeze, P Greene, S Fahn, C Freed, D Eidelber. Blinded positron emission tomography study of dopamine cell implantation for Parkinson's disease. Annals of neurology. vol 50. issue 2. 2001-12-20. PMID:11506400. |
we assessed nigrostriatal dopaminergic function in parkinson's disease (pd) patients undergoing a double-blind, placebo-controlled surgical trial of embryonic dopamine cell implantation. |
2001-12-20 |
2023-08-12 |
Not clear |
| G Eisenhofe. The role of neuronal and extraneuronal plasma membrane transporters in the inactivation of peripheral catecholamines. Pharmacology & therapeutics. vol 91. issue 1. 2001-12-19. PMID:11707293. |
in mammals, neuronal uptake of catecholamines involves the dopamine transporter (dat) at dopaminergic neurons and the norepinephrine transporter (net) at noradrenergic neurons. |
2001-12-19 |
2023-08-12 |
Not clear |
| B Dean, T Hussai. Studies on dopaminergic and GABAergic markers in striatum reveals a decrease in the dopamine transporter in schizophrenia. Schizophrenia research. vol 52. issue 1-2. 2001-12-18. PMID:11595397. |
studies on dopaminergic and gabaergic markers in striatum reveals a decrease in the dopamine transporter in schizophrenia. |
2001-12-18 |
2023-08-12 |
human |