| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beáta Sperlágh, Katalin Windisch, Rómeó D Andó, E Sylvester Viz. Neurochemical evidence that stimulation of CB1 cannabinoid receptors on GABAergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens. Neurochemistry international. vol 54. issue 7. 2009-07-15. PMID:19428788. |
neurochemical evidence that stimulation of cb1 cannabinoid receptors on gabaergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens. |
2009-07-15 |
2023-08-12 |
rat |
| Beáta Sperlágh, Katalin Windisch, Rómeó D Andó, E Sylvester Viz. Neurochemical evidence that stimulation of CB1 cannabinoid receptors on GABAergic nerve terminals activates the dopaminergic reward system by increasing dopamine release in the rat nucleus accumbens. Neurochemistry international. vol 54. issue 7. 2009-07-15. PMID:19428788. |
repeated application of n-methyl-d aspartate (1 mm) under mg(2+)-free conditions, which directly acts on dopaminergic terminals, reversibly increased the tritium efflux, but win55,212-2 did not affect n-methyl-d aspartate-evoked [(3)h]dopamine efflux, indicating that win55,212-2 has no direct action on dopaminergic nerve terminals. |
2009-07-15 |
2023-08-12 |
rat |
| Przemysław Nowak, Dariusz Nitka, Adam Kwieciński, Jadwiga Jośko, Jacek Drab, Dorota Pojda-Wilczek, Jacek Kasperski, Richard M Kostrzewa, Ryszard Bru. Neonatal co-lesion by DSP-4 and 5,7-DHT produces adulthood behavioral sensitization to dopamine D(2) receptor agonists. Pharmacological reports : PR. vol 61. issue 2. 2009-07-14. PMID:19443944. |
to assess the possible modulatory effects of noradrenergic and serotoninergic neurons on dopaminergic neuronal activity, the noradrenergic and serotoninergic neurotoxins dsp-4 n-(2-chlorethyl)-n-ethyl-2-bromobenzylamine (50.0 mg/kg, sc) and 5,7-dihydroxytryptamine (5,7-dht) (37.5 microg icv, half in each lateral ventricle), respectively, were administered towistar rats on the first and third days of postnatal ontogeny, and dopamine (da) agonist-induced behaviors were assessed in adulthood. |
2009-07-14 |
2023-08-12 |
rat |
| Jian Wang, Haiyan Lou, Courtney J Pedersen, Amanda D Smith, Ruth G Pere. 14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria. The Journal of biological chemistry. vol 284. issue 21. 2009-07-07. PMID:19289463. |
to explore if particular endogenous 14-3-3 isoforms specifically affected th activity and dopamine synthesis, we utilized rodent nigrostriatal tissues and midbrain-derived mn9d dopaminergic cells. |
2009-07-07 |
2023-08-12 |
Not clear |
| Jian Wang, Haiyan Lou, Courtney J Pedersen, Amanda D Smith, Ruth G Pere. 14-3-3zeta contributes to tyrosine hydroxylase activity in MN9D cells: localization of dopamine regulatory proteins to mitochondria. The Journal of biological chemistry. vol 284. issue 21. 2009-07-07. PMID:19289463. |
together the data support a role for 14-3-3zeta as an endogenous activator of th in midbrain dopaminergic neurons and furthermore, identify mitochondria as a potential novel site for dopamine synthesis, with implications for parkinson disease. |
2009-07-07 |
2023-08-12 |
Not clear |
| Jarom E Hanson, Elisabeth Birdsall, Kristi S Seferian, Marcus A Crosby, Kristen A Keefe, James W Gibb, Glen R Hanson, Annette E Fleckenstei. Methamphetamine-induced dopaminergic deficits and refractoriness to subsequent treatment. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19326567. |
thus, this study describes a model of resistance, possibly explained by: 1) the existence of dopaminergic neurons that are a priori refractory to deficits caused by methamphetamine; 2) the existence of dopaminergic neurons made persistently resistant consequent to a neurotoxic methamphetamine exposure; and/or 3) altered activation of post-synaptic basal ganglia systems necessary for the elaboration of methamphetamine-induced dopamine neurotoxicity. |
2009-07-07 |
2023-08-12 |
rat |
| Yanping Li, Wencheng Liu, Tinmarla F Oo, Lei Wang, Yi Tang, Vernice Jackson-Lewis, Chun Zhou, Kindiya Geghman, Mikhail Bogdanov, Serge Przedborski, M Flint Beal, Robert E Burke, Chenjian L. Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease. Nature neuroscience. vol 12. issue 7. 2009-07-07. PMID:19503083. |
we created a lrrk2 transgenic mouse model that recapitulates cardinal features of the disease: an age-dependent and levodopa-responsive slowness of movement associated with diminished dopamine release and axonal pathology of nigrostriatal dopaminergic projection. |
2009-07-07 |
2023-08-12 |
mouse |
| Karin Weissenborn, Anita B Tryc, Meike Heeren, Hans Worthmann, Henning Pflugrad, Georg Berding, Martin Bokemeyer, Hans L Tillmann, Annemarie Goldbecke. Hepatitis C virus infection and the brain. Metabolic brain disease. vol 24. issue 1. 2009-07-06. PMID:19130196. |
recently, pathologic cerebral serotonin and dopamine transporter binding and regional alterations of the cerebral glucose utilisation compatible with alterations of the dopaminergic attentional system were observed. |
2009-07-06 |
2023-08-12 |
Not clear |
| Hayato Yabe, Mohammed Emamussalehin Choudhury, Madoka Kubo, Noriko Nishikawa, Masahiro Nagai, Masahiro Nomot. Zonisamide increases dopamine turnover in the striatum of mice and common marmosets treated with MPTP. Journal of pharmacological sciences. vol 110. issue 1. 2009-07-02. PMID:19403994. |
zonisamide may help dopaminergic neurons by increasing striatal dopamine turnover following mptp treatment. |
2009-07-02 |
2023-08-12 |
mouse |
| Christian Pifl, Alexandra Wolf, Patrick Rebernik, Harald Reither, Michael L Berge. Zinc regulates the dopamine transporter in a membrane potential and chloride dependent manner. Neuropharmacology. vol 56. issue 2. 2009-07-01. PMID:19000913. |
the dopamine transporter (dat), a membrane protein specifically expressed by dopaminergic neurons and mediating the action of psychostimulants and dopaminergic neurotoxins, is regulated by zn(2+) which directly interacts with the protein. |
2009-07-01 |
2023-08-12 |
Not clear |
| Toshihiko Aosaki, Masami Miura, Masao Masud. [Physiological interaction between acetylcholine and dopamine in the striatum]. Brain and nerve = Shinkei kenkyu no shinpo. vol 61. issue 4. 2009-07-01. PMID:19378806. |
recent studies have indicated that the content of released dopamine is proportional to the firing frequency of the dopaminergic neurons unless the nicotinic receptors are activated, but it remains unaltered if the receptors are bound by acetylcholine. |
2009-07-01 |
2023-08-12 |
Not clear |
| Mette Skinbjerg, Yoon Namkung, Christer Halldin, Robert B Innis, David R Sible. Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors. Synapse (New York, N.Y.). vol 63. issue 6. 2009-06-30. PMID:19217026. |
dopaminergic signaling pathways have been extensively investigated using pet imaging, primarily with antagonist radioligands of d(2) and d(3) dopamine receptors (dars). |
2009-06-30 |
2023-08-12 |
Not clear |
| T D L Steeves, J Miyasaki, M Zurowski, A E Lang, G Pellecchia, T Van Eimeren, P Rusjan, S Houle, A P Strafell. Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. Brain : a journal of neurology. vol 132. issue Pt 5. 2009-06-24. PMID:19346328. |
we describe results of a [(11)c] raclopride positron emission tomography (pet) study comparing dopaminergic function during gambling in parkinson's disease patients, with and without pathological gambling, following dopamine agonists. |
2009-06-24 |
2023-08-12 |
Not clear |
| T D L Steeves, J Miyasaki, M Zurowski, A E Lang, G Pellecchia, T Van Eimeren, P Rusjan, S Houle, A P Strafell. Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. Brain : a journal of neurology. vol 132. issue Pt 5. 2009-06-24. PMID:19346328. |
although prior imaging studies suggest that abnormality in dopaminergic binding and dopamine release may be markers of vulnerability to addiction, this study presents the first evidence of these phenomena in pathological gambling. |
2009-06-24 |
2023-08-12 |
Not clear |
| A Taylor, F N Madison, G S Frale. Galanin-like peptide stimulates feeding and sexual behavior via dopaminergic fibers within the medial preoptic area of adult male rats. Journal of chemical neuroanatomy. vol 37. issue 2. 2009-06-22. PMID:19124073. |
to test the hypothesis that galp activates mpoa dopaminergic systems, we utilized an immunolesion technique to eliminate dopaminergic fiber input to the mpoa via a dopamine transporter-specific toxin (datsap, n=8) and compared to control injections (sap, n=8). |
2009-06-22 |
2023-08-12 |
rat |
| Mei Cui, Radha Aras, Whitney V Christian, Phillip M Rappold, Mamata Hatwar, Joseph Panza, Vernice Jackson-Lewis, Jonathan A Javitch, Nazzareno Ballatori, Serge Przedborski, Kim Tie. The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 19. 2009-06-22. PMID:19416912. |
furthermore, oct3 deletion impairs the removal of the excess extracellular dopamine induced by methamphetamine and enhances striatal dopaminergic terminal damage caused by this psychostimulant. |
2009-06-22 |
2023-08-12 |
mouse |
| Yuan Guo, Hui-Ling Wang, Xiao-Hui Xiang, Yan Zha. The role of glutamate and its receptors in mesocorticolimbic dopaminergic regions in opioid addiction. Neuroscience and biobehavioral reviews. vol 33. issue 6. 2009-06-22. PMID:19428497. |
glutamate may be involved in the process of opioid addiction not only by acting on its ionotropic and metabotropic glutamate receptors that activate several signal transduction pathways, but also by interacting with other neurotransmitters or neuropeptides such as opioids, dopamine, gamma-aminobutyric acid and substance p in the mesocorticolimbic dopaminergic regions. |
2009-06-22 |
2023-08-12 |
Not clear |
| Diptendu Chatterjee, Robert Gerla. High precision liquid chromatography analysis of dopaminergic and serotoninergic responses to acute alcohol exposure in zebrafish. Behavioural brain research. vol 200. issue 1. 2009-06-18. PMID:19378384. |
here we analyze the responses of the dopaminergic and serotoninergic neurotransmitter systems of zebrafish to acute alcohol treatment (1 h long exposure of adult fish to 0.00%, 0.25%, 0.50%, or 1.00% ethyl alcohol) by testing the concentration of dopamine, its metabolite dopac, and serotonin and its metabolite 5-hiaa from whole brain extracts. |
2009-06-18 |
2023-08-12 |
zebrafish |
| Qian Chen, Nan-Nan Huang, Jin-Tao Huang, Shen Chen, Jinjin Fan, Chaohong Li, Fu-Kang Xi. Sodium benzoate exposure downregulates the expression of tyrosine hydroxylase and dopamine transporter in dopaminergic neurons in developing zebrafish. Birth defects research. Part B, Developmental and reproductive toxicology. vol 86. issue 2. 2009-06-17. PMID:19294673. |
sodium benzoate exposure downregulates the expression of tyrosine hydroxylase and dopamine transporter in dopaminergic neurons in developing zebrafish. |
2009-06-17 |
2023-08-12 |
zebrafish |
| Shoko Nozaki, Motoichiro Kato, Harumasa Takano, Hiroshi Ito, Hidehiko Takahashi, Ryosuke Arakawa, Masaki Okumura, Yota Fujimura, Ryohei Matsumoto, Miho Ota, Akihiro Takano, Akihiko Otsuka, Fumihiko Yasuno, Yoshiro Okubo, Haruo Kashima, Tetsuya Suhar. Regional dopamine synthesis in patients with schizophrenia using L-[beta-11C]DOPA PET. Schizophrenia research. vol 108. issue 1-3. 2009-06-16. PMID:19056247. |
patients with schizophrenia showed higher dopamine synthesis in the left caudate nucleus, and dopaminergic transmission in the thalamus and right temporal cortex might be implicated in the expression of symptoms in schizophrenia. |
2009-06-16 |
2023-08-12 |
human |