| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Villa, Isabel Liste, Elise T Courtois, Emma G Seiz, Milagros Ramos, Morten Meyer, Bengt Juliusson, Philip Kusk, Alberto Martínez-Serran. Generation and properties of a new human ventral mesencephalic neural stem cell line. Experimental cell research. vol 315. issue 11. 2009-06-16. PMID:19327351. |
hvm1 cells yield a large number of dopaminergic neurons (about 12% of total cells are th+) after differentiation, which also produce dopamine. |
2009-06-16 |
2023-08-12 |
human |
| Nora D Volkow, Dardo Tomasi, Gene-Jack Wang, Frank Telang, Joanna S Fowler, Ruiliang L Wang, Jean Logan, Christopher Wong, Millard Jayne, James M Swanso. Hyperstimulation of striatal D2 receptors with sleep deprivation: Implications for cognitive impairment. NeuroImage. vol 45. issue 4. 2009-06-16. PMID:19349237. |
we find that sleep induced changes in striatal dopamine were associated with changes in cortical brain regions modulated by dopamine (attenuated deactivation of anterior cingulate gyrus and insula) but also in regions that are not recognized targets of dopaminergic modulation (attenuated activation of inferior occipital cortex and cerebellum). |
2009-06-16 |
2023-08-12 |
Not clear |
| Florence Sotty, Liliana P Montezinho, Björn Steiniger-Brach, Jacob Nielse. Phosphodiesterase 10A inhibition modulates the sensitivity of the mesolimbic dopaminergic system to D-amphetamine: involvement of the D1-regulated feedback control of midbrain dopamine neurons. Journal of neurochemistry. vol 109. issue 3. 2009-06-09. PMID:19236563. |
phosphodiesterase 10a inhibition modulates the sensitivity of the mesolimbic dopaminergic system to d-amphetamine: involvement of the d1-regulated feedback control of midbrain dopamine neurons. |
2009-06-09 |
2023-08-12 |
Not clear |
| Na K Kim, Byung H Choi, Xian Huang, Brian J Snyder, Shefqat Bukhari, Tae-Ho Kong, Hyeonseon Park, Hyung C Park, So R Park, Yoon H. Granulocyte-macrophage colony-stimulating factor promotes survival of dopaminergic neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced murine Parkinson's disease model. The European journal of neuroscience. vol 29. issue 5. 2009-06-09. PMID:19245369. |
to better understand the protective effect of gm-csf on dopaminergic neurons in parkinson's disease (pd), we investigated the effect of gm-csf on the survival of dopamine neurons and changes in locomotor behavior in a murine pd model. |
2009-06-09 |
2023-08-12 |
mouse |
| Christine Stelzel, Ulrike Basten, Christian Montag, Martin Reuter, Christian J Fiebac. Effects of dopamine-related gene-gene interactions on working memory component processes. The European journal of neuroscience. vol 29. issue 5. 2009-06-09. PMID:19291230. |
we sought evidence for this assumption by investigating the interaction effect (epistasis) of variations in two dopaminergic candidate genes: the catechol-o-methyltransferase (comt) val(158)met polymorphism, which has been shown to influence prefrontal dopamine concentration, and the drd2/ankk1-taq-ia polymorphism, which has been related to the density of d2 receptors. |
2009-06-09 |
2023-08-12 |
human |
| I Léna, S Bradshaw, J Pintar, I Kitche. Adaptive changes in the expression of central opioid receptors in mice lacking the dopamine D2 receptor gene. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18424009. |
on the basis of numerous studies that have described interactions between the dopaminergic and opioidergic systems, we have investigated whether genetic deletion of dopamine d2 receptors (d2r) might influence the expression of central opioid receptors. |
2009-06-08 |
2023-08-12 |
mouse |
| Hsing-Chen Tsai, Feng Zhang, Antoine Adamantidis, Garret D Stuber, Antonello Bonci, Luis de Lecea, Karl Deisserot. Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science (New York, N.Y.). vol 324. issue 5930. 2009-06-04. PMID:19389999. |
natural rewards and drugs of abuse can alter dopamine signaling, and ventral tegmental area (vta) dopaminergic neurons are known to fire action potentials tonically or phasically under different behavioral conditions. |
2009-06-04 |
2023-08-12 |
Not clear |
| Ikuko Miyazaki, Masato Asanum. Approaches to prevent dopamine quinone-induced neurotoxicity. Neurochemical research. vol 34. issue 4. 2009-06-03. PMID:18770028. |
dopamine (da) and its metabolites containing two hydroxyl residues exert cytotoxicity in dopaminergic neuronal cells, primarily due to the generation of highly reactive da and dopa quinones. |
2009-06-03 |
2023-08-12 |
Not clear |
| Gavin D Phillips, Paul K Hitchcot. Blockade of the acquisition, but not expression, of associative learning by pre-session intra-amygdala R(+) 7-OH-DPAT. Psychopharmacology. vol 203. issue 1. 2009-06-02. PMID:18949458. |
two issues were addressed regarding the effects of amygdala dopamine manipulations on associative learning: first, an apparent contradiction between the effects of post- vs. pre-session dopaminergic manipulations and second, the ability of dopaminergic infusions to affect association formation vs. its expression following extended training. |
2009-06-02 |
2023-08-12 |
Not clear |
| Chandra C Cardoso, Kelly R Lobato, Ricardo W Binfaré, Priscilla K Ferreira, Angelo O Rosa, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19059299. |
a 5-ht(1a) receptor antagonist), way100635 (0.1 mg/kg, s.c., a selective 5-ht(1a) receptor antagonist), ritanserin (4 mg/kg, i.p., a 5-ht(2a/2c) receptor antagonist), ketanserin (5 mg/kg, a preferential 5-ht(2a) receptor antagonist), prazosin (1 mg/kg, i.p., an alpha(1)-adrenoceptor antagonist), yohimbine (1 mg/kg, i.p., an alpha(2)-adrenoceptor antagonist), haloperidol (0.2 mg/kg, i.p., a non selective dopaminergic receptor antagonist), sch23390 (0.05 mg/kg, s.c., a dopamine d(1) receptor antagonist) or sulpiride (50 mg/kg, i.p., a dopamine d(2) receptor antagonist) 30 min before the administration of magnesium chloride (30 mg/kg, i.p.) |
2009-06-02 |
2023-08-12 |
mouse |
| Chandra C Cardoso, Kelly R Lobato, Ricardo W Binfaré, Priscilla K Ferreira, Angelo O Rosa, Adair Roberto S Santos, Ana Lúcia S Rodrigue. Evidence for the involvement of the monoaminergic system in the antidepressant-like effect of magnesium. Progress in neuro-psychopharmacology & biological psychiatry. vol 33. issue 2. 2009-06-02. PMID:19059299. |
in conclusion, the present study provides evidence indicating that the antidepressant-like effect of magnesium in the fst is dependent on its interaction with the serotonergic (5-ht(1a) and 5-ht(2a/2c) receptors), noradrenergic (alpha(1)- and alpha(2)- receptors) and dopaminergic (dopamine d(1) and d(2) receptors) systems. |
2009-06-02 |
2023-08-12 |
mouse |
| Donald Grosse. Dopamine agonists and therapy compliance. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 29 Suppl 5. 2009-06-02. PMID:19381766. |
dds, probably attributed to pulsatile overstimulation of the limbic dopaminergic system, is characterised by severe dopamine addiction and behavioural disorders such as pathological gambling (pg), hypersexuality, punding and mood swings. |
2009-06-02 |
2023-08-12 |
Not clear |
| Per Odin, Erik Wolters, Angelo Antonin. Continuous dopaminergic stimulation achieved by duodenal levodopa infusion. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 29 Suppl 5. 2009-06-02. PMID:19381770. |
continuous dopaminergic stimulation is the ideal approach for the management of parkinson's disease (pd); this goal can be partially reached with dopamine agonists, but the need for a therapeutic strategy providing a strong and constant dopaminergic stimulation also in the advanced phase of the disease remains unmet. |
2009-06-02 |
2023-08-12 |
Not clear |
| J Costenti. [A new pharmacological strategy for schizophrenia: the partial agonists of D2 dopaminergic receptors. The principle characteristics of aripiprazole]. L'Encephale. vol 35. issue 1. 2009-06-01. PMID:19250996. |
this partial agonist, by stimulating d2 and d3 dopamine autoreceptors, moderates the functioning of hyperactive dopaminergic neurones. |
2009-06-01 |
2023-08-12 |
Not clear |
| J Costenti. [A new pharmacological strategy for schizophrenia: the partial agonists of D2 dopaminergic receptors. The principle characteristics of aripiprazole]. L'Encephale. vol 35. issue 1. 2009-06-01. PMID:19250996. |
on the other hand, the occupation by aripiprazole of the d2 receptors that are not stimulated by dopamine (on account of an insufficient presynaptic dopaminergic activity) restores a certain amount of stimulation, which partly alleviates negative expressions of schizophrenia. |
2009-06-01 |
2023-08-12 |
Not clear |
| Nicola Clausius, Christoph Born, Heinz Grunz. [The relevance of dopamine agonists in the treatment of depression]. Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater. vol 23. issue 1. 2009-06-01. PMID:19272288. |
results of different studies also support a role of the dopaminergic system in depression: in particular, psychomotor retarded depressive patients exhibited lower levels of homovanillic acid (metabolite of dopamine). |
2009-06-01 |
2023-08-12 |
Not clear |
| Nicola Clausius, Christoph Born, Heinz Grunz. [The relevance of dopamine agonists in the treatment of depression]. Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater. vol 23. issue 1. 2009-06-01. PMID:19272288. |
while the moodimproving effect of methylphenidat, d-amphetamine and cocaine is also supportive for an involvement of the dopaminergic system, reserpine leads to diminished dopamine levels and may induce a depressive syndrome as well as dopamine receptor-blockers. |
2009-06-01 |
2023-08-12 |
Not clear |
| Nuria Flames, Oliver Hober. Gene regulatory logic of dopamine neuron differentiation. Nature. vol 458. issue 7240. 2009-05-29. PMID:19287374. |
here we show that a simple cis-regulatory element, the dopamine (da) motif, controls the expression of all dopamine pathway genes in all dopaminergic cell types in caenorhabditis elegans. |
2009-05-29 |
2023-08-12 |
mouse |
| Michael G Vaughn, Kevin M Beaver, Matt DeLisi, Matthew O Howard, Brian E Perro. Dopamine D4 receptor gene exon III polymorphism associated with binge drinking attitudinal phenotype. Alcohol (Fayetteville, N.Y.). vol 43. issue 3. 2009-05-28. PMID:19393859. |
although binge drinking is a serious public health problem, relatively few studies have investigated the relationship between specific dopaminergic genes such as the dopamine d4 receptor (drd4) and binge drinking attitudinal phenotypes. |
2009-05-28 |
2023-08-12 |
Not clear |
| Lane J Wallace, Rachel M Hughe. Computational analysis of stimulated dopaminergic synapses suggests release largely occurs from a single pool of vesicles. Synapse (New York, N.Y.). vol 62. issue 12. 2009-05-26. PMID:18792991. |
results from several experiments monitoring extracellular dopamine (da) after stimulating axons at high frequencies have been interpreted as evidence for release from two populations of vesicles in dopaminergic varicosities. |
2009-05-26 |
2023-08-12 |
Not clear |