| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T A Slotkin, W L Whitmore, L Lerea, R J Slepetis, S J Weigel, P A Trepanier, F J Seidle. Role of ornithine decarboxylase and the polyamines in nervous system development: Short-term postnatal administration of α-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 1. issue 1. 2014-06-02. PMID:24875600. |
development of the adrenal medulla, a peripheral catecholaminergic tissue which displays approximately the same developmental profile as do sympathetic neurons but which does not develop axonal projections, was not slowed by dfmo treatment; similarly, central noradrenergic and dopaminergic neurons, which undergo the majority of axonal outgrowth and synaptogenesis during the second to third postnatal week (just after the period in which polyamines returned to control levels), developed normally as assessed by measurements of transmitter levels, tyrosine hydroxylase activity and synaptosomal uptake of [(3)h]norepinephrine or [(3)h]dopamine. |
2014-06-02 |
2023-08-13 |
rat |
| Benjawan Meesarapee, Anusorn Thampithak, Yamaratee Jaisin, Pimtip Sanvarinda, Apichart Suksamrarn, Patoomratana Tuchinda, Noppawan Phumala Morales, Yupin Sanvarind. Curcumin I mediates neuroprotective effect through attenuation of quinoprotein formation, p-p38 MAPK expression, and caspase-3 activation in 6-hydroxydopamine treated SH-SY5Y cells. Phytotherapy research : PTR. vol 28. issue 4. 2014-05-30. PMID:23857913. |
6-hydroxydopamine (6-ohda) selectively enters dopaminergic neurons and undergoes auto-oxidation resulting in the generation of reactive oxygen species and dopamine quinones, subsequently leading to apoptosis. |
2014-05-30 |
2023-08-12 |
Not clear |
| Ilaria Bonoldi, O D Howe. The enduring centrality of dopamine in the pathophysiology of schizophrenia: in vivo evidence from the prodrome to the first psychotic episode. Advances in pharmacology (San Diego, Calif.). vol 68. 2014-05-29. PMID:24054146. |
studies using these approaches have identified that the major locus of dopaminergic dysfunction is presynaptic, characterized by elevated dopamine synthesis and release capacity. |
2014-05-29 |
2023-08-12 |
Not clear |
| David Arkadir, Hagai Bergman, Stanley Fah. Redundant dopaminergic activity may enable compensatory axonal sprouting in Parkinson disease. Neurology. vol 82. issue 12. 2014-05-27. PMID:24663231. |
redundant information encoding results from the similarity of representation of salient and rewarding events by many dopaminergic neurons, from the wide axonal field of a single dopaminergic neuron in the striatum, and from the nonspecific spatial effect of dopamine on striatal neurons (volume conductance). |
2014-05-27 |
2023-08-12 |
human |
| Morteza Zendehdel, Keyvan Hasani, Vahab Babapour, Sepideh Seyedali Mortezaei, Yalda Khoshbakht, Shahin Hassanpou. Dopamine-induced hypophagia is mediated by D1 and 5HT-2c receptors in chicken. Veterinary research communications. vol 38. issue 1. 2014-05-22. PMID:24122738. |
these results suggest that dopamine decrease food intake via d1 receptor and there is an interaction between dopaminergic and serotonergic systems via 5-ht2c receptor in chickens. |
2014-05-22 |
2023-08-12 |
chicken |
| Ana I Rodriguez-Perez, Antonio Dominguez-Meijide, Jose L Lanciego, Maria J Guerra, Jose L Labandeira-Garci. Dopaminergic degeneration is enhanced by chronic brain hypoperfusion and inhibited by angiotensin receptor blockage. Age (Dordrecht, Netherlands). vol 35. issue 5. 2014-05-20. PMID:22986582. |
chronic hypoperfusion induced significant loss of dopaminergic neurons and striatal dopaminergic terminals and a reduction in striatal dopamine levels. |
2014-05-20 |
2023-08-12 |
rat |
| Nicolaas I Bohnen, Klaus Jah. Imaging: What can it tell us about parkinsonian gait? Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 11. 2014-05-19. PMID:24132837. |
dopamine displacement imaging studies have shown evidence for a mesofrontal dopaminergic shift from a depleted striatum in parkinsonian gait. |
2014-05-19 |
2023-08-12 |
Not clear |
| Chad R Jackson, Megan Capozzi, Heng Dai, Douglas G McMaho. Circadian perinatal photoperiod has enduring effects on retinal dopamine and visual function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 13. 2014-05-19. PMID:24672008. |
dopamine levels were significantly lower in short photoperiod mice, and dopaminergic agonist treatment rescued the photopic light response deficits. |
2014-05-19 |
2023-08-12 |
mouse |
| Riitta Lindström, Päivi Lindholm, Jukka Kallijärvi, Li-Ying Yu, T Petteri Piepponen, Urmas Arumäe, Mart Saarma, Tapio I Hein. Characterization of the structural and functional determinants of MANF/CDNF in Drosophila in vivo model. PloS one. vol 8. issue 9. 2014-05-16. PMID:24019940. |
in drosophila, the sole manf protein (dmmanf) is needed for the maintenance of dopaminergic neurites and dopamine levels. |
2014-05-16 |
2023-08-12 |
human |
| Bernardo Stutz, Fabio Silva Lima da Conceição, Luís Eduardo Santos, Daniel Veloso Cadilhe, Renata L Fleming, Mariana Acquarone, Patrícia F Gardino, Ricardo A de Melo Reis, Phillip W Dickson, Peter R Dunkley, Stevens Rehen, Jean-Christophe Houzel, Fernando G de Mell. Murine dopaminergic Müller cells restore motor function in a model of Parkinson's disease. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24117434. |
these dopaminergic components are active, since müller cells are able to synthesize and release dopamine to the extracellular medium. |
2014-05-14 |
2023-08-12 |
mouse |
| Bernardo Stutz, Fabio Silva Lima da Conceição, Luís Eduardo Santos, Daniel Veloso Cadilhe, Renata L Fleming, Mariana Acquarone, Patrícia F Gardino, Ricardo A de Melo Reis, Phillip W Dickson, Peter R Dunkley, Stevens Rehen, Jean-Christophe Houzel, Fernando G de Mell. Murine dopaminergic Müller cells restore motor function in a model of Parkinson's disease. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24117434. |
to address the potential use of dopaminergic müller cells as a source of dopamine in cell therapy procedures, we used a mouse model of parkinson's disease, in which mouse müller cells with the dopaminergic phenotype were transplanted into the striatum of hemi-parkinsonian mice generated by unilateral injection of 6-hydroxydopamine. |
2014-05-14 |
2023-08-12 |
mouse |
| Bernardo Stutz, Fabio Silva Lima da Conceição, Luís Eduardo Santos, Daniel Veloso Cadilhe, Renata L Fleming, Mariana Acquarone, Patrícia F Gardino, Ricardo A de Melo Reis, Phillip W Dickson, Peter R Dunkley, Stevens Rehen, Jean-Christophe Houzel, Fernando G de Mell. Murine dopaminergic Müller cells restore motor function in a model of Parkinson's disease. Journal of neurochemistry. vol 128. issue 6. 2014-05-14. PMID:24117434. |
the data indicate local restoration of dopaminergic signaling in hemi-parkinsonian mice confirmed by measurement of striatal dopamine after müller cell grafting. |
2014-05-14 |
2023-08-12 |
mouse |
| Christian Hölsche. Central effects of GLP-1: new opportunities for treatments of neurodegenerative diseases. The Journal of endocrinology. vol 221. issue 1. 2014-05-12. PMID:23999914. |
in animal models of pd, exendin-4 showed protection of dopaminergic neurons in the substantia nigra and prevention of dopamine loss in the basal ganglia while preserving motor control. |
2014-05-12 |
2023-08-12 |
Not clear |
| Daniel E Olazábal, Mariana Pereira, Daniella Agrati, Annabel Ferreira, Alison S Fleming, Gabriela González-Mariscal, Frederic Lévy, Aldo B Lucion, Joan I Morrell, Michael Numan, Natalia Uriart. New theoretical and experimental approaches on maternal motivation in mammals. Neuroscience and biobehavioral reviews. vol 37. issue 8. 2014-05-08. PMID:23608127. |
we review the evidence supporting dopamine mediation of maternal motivation and describe how different phases of the dopaminergic response - basal, tonic, and phasic release in the nucleus accumbens - relate to increased salience, invigorating behavior, and behavioral switching. |
2014-05-08 |
2023-08-12 |
Not clear |
| Bianca C Wittmann, Geoffrey C Tan, John E Lisman, Raymond J Dolan, Emrah Düze. DAT genotype modulates striatal processing and long-term memory for items associated with reward and punishment. Neuropsychologia. vol 51. issue 11. 2014-05-08. PMID:23911780. |
these findings suggest that processing of appetitive and aversive motivation in the human striatum involve the dopaminergic system and that dopamine plays a role in memory for both types of motivational information. |
2014-05-08 |
2023-08-12 |
human |
| David Devos, Caroline Moreau, Kathy Dujardin, Ioav Cabantchik, Luc Defebvre, Regis Borde. New pharmacological options for treating advanced Parkinson's disease. Clinical therapeutics. vol 35. issue 10. 2014-05-07. PMID:24011636. |
given that the loss of dopamine in the striatum is the main pathochemical hallmark of pd, pharmacological treatment of the disease has focused on restoring dopaminergic neurotransmission and thus improving motor symptoms. |
2014-05-07 |
2023-08-12 |
Not clear |
| David Devos, Caroline Moreau, Kathy Dujardin, Ioav Cabantchik, Luc Defebvre, Regis Borde. New pharmacological options for treating advanced Parkinson's disease. Clinical therapeutics. vol 35. issue 10. 2014-05-07. PMID:24011636. |
firstly, dopaminergic medications modulate all the key steps in dopamine transmission other than the most powerful determinant of extracellular dopamine levels: the activity of the presynaptic dopamine transporter. |
2014-05-07 |
2023-08-12 |
Not clear |
| Eugénie Lhommée, Alina Batir, Jean-Louis Quesada, Claire Ardouin, Valérie Fraix, Eric Seigneuret, Stéphan Chabardès, Alim-Louis Benabid, Pierre Pollak, Paul Krac. Dopamine and the biology of creativity: lessons from Parkinson's disease. Frontiers in neurology. vol 5. 2014-05-05. PMID:24795692. |
we aim at demonstrating that creativity can be induced by dopaminergic treatments in pd, and tends to disappear after withdrawal of dopamine agonists. |
2014-05-05 |
2023-08-13 |
Not clear |
| Jonathan E Hill, Paul J Gasse. Organic cation transporter 3 is densely expressed in the intercalated cell groups of the amygdala: anatomical evidence for a stress hormone-sensitive dopamine clearance system. Journal of chemical neuroanatomy. vol 52. 2014-05-02. PMID:23694905. |
in this study, we used immunohistochemical and immunofluorescence techniques to examine the distribution of oct3 in the itc, to identify the phenotype of oct3-expressing cells, and to describe the spatial relationships of oct3 to dopaminergic terminals and dopamine d1 receptors in these areas. |
2014-05-02 |
2023-08-12 |
rat |
| Jonathan E Hill, Paul J Gasse. Organic cation transporter 3 is densely expressed in the intercalated cell groups of the amygdala: anatomical evidence for a stress hormone-sensitive dopamine clearance system. Journal of chemical neuroanatomy. vol 52. 2014-05-02. PMID:23694905. |
these anatomical data are consistent with the hypothesis that oct3 plays a central role in regulating dopaminergic neurotransmission in the itc, and that it represents a post- or peri-synaptic dopamine clearance mechanism. |
2014-05-02 |
2023-08-12 |
rat |