| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rou Gu, Jianyu Pan, Maher Un Nisa Awan, Xiaowei Sun, Fang Yan, Liping Bai, Jie Ba. The major histocompatibility complex participates in Parkinson's disease. Pharmacological research. 2024-04-07. PMID:38583689. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra and the aggregation of alpha-synuclein (α-syn). |
2024-04-07 |
2024-04-10 |
Not clear |
| Ya-Shi Wu, Wen-Han Zheng, Tai-Hang Liu, Yan Sun, Yu-Ting Xu, Li-Zhen Shao, Qin-Yu Cai, Ya Qin Tan. Joint-tissue integrative analysis identifies high-risk genes for Parkinson's disease. Frontiers in neuroscience. vol 18. 2024-04-05. PMID:38576865. |
the loss of dopaminergic neurons in the substantia nigra and the abnormal accumulation of synuclein proteins and neurotransmitters in lewy bodies constitute the primary symptoms of parkinson's disease (pd). |
2024-04-05 |
2024-04-07 |
Not clear |
| Thomas Paß, Konrad M Ricke, Pierre Hofmann, Roy S Chowdhury, Yu Nie, Patrick Chinnery, Heike Endepols, Bernd Neumaier, André Carvalho, Lionel Rigoux, Sophie M Steculorum, Julien Prudent, Trine Riemer, Markus Aswendt, Birgit Liss, Bent Brachvogel, Rudolf J Wiesne. Preserved striatal innervation maintains motor function despite severe loss of nigral dopaminergic neurons. Brain : a journal of neurology. 2024-04-04. PMID:38574200. |
degeneration of dopaminergic neurons in the substantia nigra and their striatal axon terminals causes cardinal motor symptoms of parkinson's disease. |
2024-04-04 |
2024-04-07 |
mouse |
| Tomaz Rus, Anka Cuderman, Dejan Georgie. Parkinsonism Associated With Traumatic Hemorrhage in Substantia Nigra: Role of Presynaptic Dopaminergic Imaging. Neurology. vol 102. issue 9. 2024-04-04. PMID:38574327. |
parkinsonism associated with traumatic hemorrhage in substantia nigra: role of presynaptic dopaminergic imaging. |
2024-04-04 |
2024-04-07 |
Not clear |
| Mingxue Song, Yalong Qiang, Shuai Wang, Shan Shan, Liwen Zhang, Caipei Liu, Fuyong Song, Xiulan Zha. High-fat diet exacerbates 1-Bromopropane-induced loss of dopaminergic neurons in the substantia nigra of mice through mitochondrial damage associated necroptotic pathway. Ecotoxicology and environmental safety. vol 276. 2024-04-04. PMID:38574648. |
high-fat diet exacerbates 1-bromopropane-induced loss of dopaminergic neurons in the substantia nigra of mice through mitochondrial damage associated necroptotic pathway. |
2024-04-04 |
2024-04-07 |
mouse |
| Priyadarshi Prajjwal, Nikhil Deep Kolanu, Yeruva Bheemeswara Reddy, Aneeqa Ahmed, Mohammed Dheyaa Marsool Marsool, Krupanagram Santoshi, Himani Harshad Pattani, Jobby John, Kiran Kishor Chandrasekar, Omniat Amir Hussi. Association of Parkinson's disease to Parkinson's plus syndromes, Lewy body dementia, and Alzheimer's dementia. Health science reports. vol 7. issue 4. 2024-04-02. PMID:38562616. |
it is caused by the death of dopaminergic neurons, particularly in the substantia nigra. |
2024-04-02 |
2024-04-04 |
Not clear |
| Juan U Mascotte-Cruz, Arturo Vera, Lorenzo Leija, Francisco E Lopez-Salas, Michael Gradzielski, Joachim Koetz, Bismark Gatica-García, C P Rodríguez-Oviedo, Irais E Valenzuela-Arzeta, Lourdes Escobedo, David Reyes-Corona, M E Gutierrez-Castillo, Minerva Maldonado-Berny, Armando J Espadas-Alvarez, Carlos E Orozco-Barrios, Daniel Martinez-Fon. Focused ultrasound on the substantia nigra enables safe neurotensin-polyplex nanoparticle-mediated gene delivery to dopaminergic neurons intranasally and by blood circulation. Discover nano. vol 19. issue 1. 2024-04-02. PMID:38564106. |
focused ultrasound on the substantia nigra enables safe neurotensin-polyplex nanoparticle-mediated gene delivery to dopaminergic neurons intranasally and by blood circulation. |
2024-04-02 |
2024-04-04 |
rat |
| Heba M Mansour, Ahmed F Mohamed, Mahmoud M Khattab, Aiman S El-Khati. Unveiling the therapeutic prospects of EGFR inhibition in rotenone-mediated parkinsonism in rats: Modulation of dopamine D3 receptor. Brain research. 2024-03-30. PMID:38554797. |
our findings indicate that lap effectively alleviated motor impairment, improved histopathological abnormalities, and restored dopaminergic neurons in the substantia nigra. |
2024-03-30 |
2024-04-02 |
rat |
| Heba M Mansour, Ahmed F Mohamed, Mahmoud M Khattab, Aiman S El-Khati. Unveiling the therapeutic prospects of EGFR inhibition in rotenone-mediated parkinsonism in rats: Modulation of dopamine D3 receptor. Brain research. 2024-03-30. PMID:38554797. |
parkinson's disease (pd) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. |
2024-03-30 |
2024-04-02 |
rat |
| S S Lövdal, G Carli, B Orso, M Biehl, D Arnaldi, P Mattioli, A Janzen, E Sittig, S Morbelli, J Booij, W H Oertel, K L Leenders, S K Mele. Investigating the aspect of asymmetry in brain-first versus body-first Parkinson's disease. NPJ Parkinson's disease. vol 10. issue 1. 2024-03-30. PMID:38555343. |
parkinson's disease (pd) is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. |
2024-03-30 |
2024-04-02 |
Not clear |
| Meghan L Bucher, Amy R Dunn, Joshua M Bradner, Kristen Stout Egerton, James P Burkett, Michelle A Johnson, Gary W Mille. Synaptic vesicle glycoprotein 2C enhances vesicular storage of dopamine and counters dopaminergic toxicity. The European journal of neuroscience. 2024-03-27. PMID:38532289. |
dopaminergic neurons of the substantia nigra exist in a persistent state of vulnerability resulting from high baseline oxidative stress, high-energy demand, and broad unmyelinated axonal arborisations. |
2024-03-27 |
2024-03-29 |
mouse |
| Noelia Morales-Prieto, Rebekah Bevans, Adam O'Mahony, Aaron Barron, Conor Giles Doran, Erin McCarthy, Ruth M Concannon, Susan R Goulding, Cathal M McCarthy, Louise M Collins, Aideen M Sullivan, Gerard W O'Keeff. Human α-synuclein overexpression upregulates SKOR1 in a rat model of simulated nigrostriatal ageing. Aging cell. 2024-03-26. PMID:38529808. |
parkinson's disease (pd) is characterised by progressive loss of dopaminergic (da) neurons from the substantia nigra (sn) and α-synuclein (αsyn) accumulation. |
2024-03-26 |
2024-03-28 |
human |
| Nazlı Durmaz Celik, Serkan Ozben, Tomris Ozbe. Unveiling Parkinson's disease through biomarker research: current insights and future prospects. Critical reviews in clinical laboratory sciences. 2024-03-26. PMID:38529882. |
parkinson's disease (pd) is a neurodegenerative condition marked by the gradual depletion of dopaminergic neurons in the substantia nigra. |
2024-03-26 |
2024-03-28 |
Not clear |
| Jianing Shen, Junhua Xie, Liyuan Ye, Jian Mao, Shihao Sun, Weiwei Chen, Sijia Wei, Sisi Ruan, Linhai Wang, Hangcui Hu, Jingjing Wei, Yao Zheng, Zhouyan Xi, Ke Wang, Yan X. Neuroprotective effect of green tea extract (-)-epigallocatechin-3-gallate in a preformed fibril-induced mouse model of Parkinson's disease. Neuroreport. 2024-03-25. PMID:38526966. |
parkinson's disease (pd) is the second most common neurodegenerative disease characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra (sn). |
2024-03-25 |
2024-03-28 |
mouse |
| Lihong Deng, Wei Wei, Chunxia Qiao, Yubing Yin, Xiaojing Li, Hua Yu, Lingqi Jian, Xiaohong Ma, Liansheng Zhao, Qiang Wang, Wei Deng, Wanjun Guo, Tao L. Dynamic aberrances of substantia nigra-relevant coactivation patterns in first-episode treatment-naïve patients with schizophrenia. Psychological medicine. 2024-03-25. PMID:38523252. |
this study investigates the dynamic coactivation patterns (caps) associated with the substantia nigra (sn), a key dopaminergic nucleus, in first-episode treatment-naïve patients with schizophrenia (fes). |
2024-03-25 |
2024-03-27 |
Not clear |
| Hayder M Al-Kuraishy, Esraa H Fahad, Salah Al-Windy, Suzy A El-Sherbeni, Walaa A Negm, Gaber El-Saber Batih. The effects of cholesterol and statins on Parkinson's neuropathology: a narrative review. Inflammopharmacology. 2024-03-19. PMID:38499742. |
pd neuropathology is due to the progressive degeneration of dopaminergic neurons in the substantia nigra and accumulation of lewy bodies in the survival neurons. |
2024-03-19 |
2024-03-21 |
Not clear |
| A Amini, F Esmaeili, M Golpic. Possible role of lncRNAs in amelioration of Parkinson's disease symptoms by transplantation of dopaminergic cells. NPJ Parkinson's disease. vol 10. issue 1. 2024-03-13. PMID:38472261. |
behavioral and histopathological examinations revealed that cell transplantation partially compensated dopaminergic cell degeneration in st and substantia nigra (sn) of pd rats. |
2024-03-13 |
2024-03-15 |
rat |
| b' Ma\\xc5\\x82gorzata Wojtkowska, Natalia Karczewska, Klaudia Pacewicz, Andrzej Pacak, Piotr Kope\\xc4\\x87, Jolanta Florczak-Wyspia\\xc5\\x84ska, Karolina Pop\\xc5\\x82awska-Domaszewicz, Tomasz Ma\\xc5\\x82kiewicz, Bartosz Sok\\xc3\\xb3\\xc5\\x8. Quantification of Circulating Cell-Free DNA in Idiopathic Parkinson\'s Disease Patients. International journal of molecular sciences. vol 25. issue 5. 2024-03-13. PMID:38474065.' |
parkinson's disease (pd) is one of the most common neurodegenerative disorders globally and leads to an excessive loss of dopaminergic neurons in the substantia nigra of the brain. |
2024-03-13 |
2024-03-15 |
Not clear |
| Hae-In Choi, Taeheon Kim, Jin Woo Kim, Gi Ju Lee, Jinyoung Choi, Yoon-Jee Chae, Eunhee Kim, Tae-Sung Ko. Rat Pharmacokinetics and In Vitro Metabolite Identification of KM-819, a Parkinson's Disease Candidate, Using LC-MS/MS and LC-HRMS. Molecules (Basel, Switzerland). vol 29. issue 5. 2024-03-13. PMID:38474516. |
in patients with parkinson's disease, faf1 is overexpressed in dopaminergic neurons in the substantia nigra. |
2024-03-13 |
2024-03-15 |
human |
| Ziliang He, Yeye Hu, Ying Zhang, Jing Xie, Zhiqiang Niu, Guigui Yang, Ji Zhang, Zixuan Zhao, Shuai Wei, Haifeng Wu, Weicheng H. Asiaticoside exerts neuroprotection through targeting NLRP3 inflammasome activation. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 127. 2024-03-12. PMID:38471370. |
parkinson's disease (pd), a neurodegenerative disorder, is characterized by motor symptoms due to the progressive loss of dopaminergic neurons in the substantia nigra (sn) and striatum (str), alongside neuroinflammation. |
2024-03-12 |
2024-03-15 |
Not clear |