| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Sarrieau, F Javoy-Agid, P Kitabgi, M Dussaillant, M Vial, J P Vincent, Y Agid, W H Rostèn. Characterization and autoradiographic distribution of neurotensin binding sites in the human brain. Brain research. vol 348. issue 2. 1986-01-28. PMID:4075096. |
high density of 125i-nt binding sites were mainly found in dopaminergic (da)-rich areas such as the substantia nigra, the ventral tegmental area, the striatum and the nucleus accumbens, further supporting an interaction between nt and da neurons in human brain. |
1986-01-28 |
2023-08-11 |
human |
| A N van den Pol, A D Smith, J F Powel. GABA axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry with biotin-peroxidase and protein A-colloidal gold. Brain research. vol 348. issue 1. 1986-01-22. PMID:2866017. |
by means of this procedure it has been possible to show that gabaergic axon terminals (containing glutamate decarboxylase) are in synaptic contact with the cell bodies and dendrites of dopaminergic neurons (containing tyrosine hydroxylase) in the substantia nigra of the rat. |
1986-01-22 |
2023-08-11 |
rat |
| D L Toan, W Schult. Responses of rat pallidum cells to cortex stimulation and effects of altered dopaminergic activity. Neuroscience. vol 15. issue 3. 1986-01-22. PMID:2866467. |
the dopaminergic influences on this corticopallidal impulse transmission were assessed by the systemic administration of the dopamine receptor-blocking neuroleptics, haloperidol and fluphenazine, as well as by conditioning electrical stimulation of the substantia nigra. |
1986-01-22 |
2023-08-11 |
rat |
| A Smiałowsk. Stimulation of hippocampal dopaminergic receptors: behavioral and electrophysiological effects. Polish journal of pharmacology and pharmacy. vol 37. issue 3. 1986-01-09. PMID:2866502. |
it was found that hippocampal dopaminergic afferents in the rat originate in the ventral tegmental area and the medial part of substantia nigra. |
1986-01-09 |
2023-08-11 |
rat |
| T L Perry, V W Yong, R M Clavier, K Jones, J M Wright, J G Foulks, R A Wal. Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse. Neuroscience letters. vol 60. issue 2. 1985-12-18. PMID:3877260. |
c57 black mice given a single injection of n-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp), 40 mg/kg, developed marked reduction of striatal dopamine content and loss of dopaminergic neurons in the zona compacta of the substantia nigra. |
1985-12-18 |
2023-08-11 |
mouse |
| A Lydén, U Bondesson, B S Larsson, N G Lindquist, L I Olsso. Autoradiography of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): uptake in the monoaminergic pathways and in melanin containing tissues. Acta pharmacologica et toxicologica. vol 57. issue 2. 1985-12-13. PMID:3877403. |
mptp seems to selectively destroy the melanin containing dopaminergic cells in pars compacta of substantia nigra. |
1985-12-13 |
2023-08-11 |
mouse |
| M L Bouthenet, N Sales, J C Schwart. Autoradiographic localisation of 3H-apomorphine binding sites in rat brain. Naunyn-Schmiedeberg's archives of pharmacology. vol 330. issue 1. 1985-11-15. PMID:2995839. |
labelling of areas of origin of the cerebral dopaminergic neurons in substantia nigra or ventral tegmental area were also observed. |
1985-11-15 |
2023-08-11 |
rat |
| S Okuyama, S Hashimoto, H Aihar. Effects on the caudate spindle in rats of taurine and gamma-aminobutyric acid (GABA) microinjected into the substantia nigra: involvement of the dopaminergic system. Brain research. vol 342. issue 2. 1985-11-12. PMID:4041839. |
effects on the caudate spindle in rats of taurine and gamma-aminobutyric acid (gaba) microinjected into the substantia nigra: involvement of the dopaminergic system. |
1985-11-12 |
2023-08-11 |
rat |
| J M Durand-Gorde, J Bert, A Nieoullo. Changes in tyrosine hydroxylase, glutamic acid decarboxylase and choline acetyltransferase after local microinoculation of scrapie agent into the nigrostriatal system of the golden hamster. Brain research. vol 341. issue 2. 1985-11-04. PMID:2864098. |
the microinoculation of a homogenate of an infected brain unilaterally into the substantia nigra (sn) provokes a decrease in tyrosine hydroxylase (th), the synthesizing enzyme for dopamine in the dopaminergic neurones, in the striatum ipsilateral to the injected sn. |
1985-11-04 |
2023-08-11 |
Not clear |
| B Zivkovic, A Oblin, G Bartholin. Progabide reverses the nigral substance P reduction induced by chronic impairment of dopaminergic transmission. European journal of pharmacology. vol 112. issue 2. 1985-10-09. PMID:2411575. |
repeated treatment with haloperidol or lesion of nigrostriatal dopaminergic neurons with 6-hydroxydopamine produced a reduction in substance p immunoreactivity in the rat substantia nigra. |
1985-10-09 |
2023-08-11 |
rat |
| B Guerin, C Silice, P Mouchet, C Feuerstein, P Demeng. Changes of the striatal 3H-spiperone binding 3-6 weeks after nigrostriatal denervation and after two years. Life sciences. vol 37. issue 10. 1985-10-09. PMID:3162072. |
a complete unilateral lesion of the nigrostriatal pathway by 6-hydroxydopamine injection in the substantia nigra induced a drastic increase in striatal dopaminergic binding sites labelled by 3h-spiperone, 30 days after the lesion. |
1985-10-09 |
2023-08-11 |
Not clear |
| L Dydyk, E Medyńska, O Puciłowsk. [Identification of dopaminergic vesicles in the electron-microscopic picture of the compact layer of the substantia nigra in the rat]. Neuropatologia polska. vol 23. issue 1. 1985-10-01. PMID:4033951. |
[identification of dopaminergic vesicles in the electron-microscopic picture of the compact layer of the substantia nigra in the rat]. |
1985-10-01 |
2023-08-11 |
rat |
| G Nappi, F Petraglia, E Martignoni, F Facchinetti, G Bono, A R Genazzan. beta-Endorphin cerebrospinal fluid decrease in untreated parkinsonian patients. Neurology. vol 35. issue 9. 1985-09-26. PMID:2991818. |
the parkinson's disease-related decrease of csf beta-ep levels further supports the concept that there is a generalized brain disorder in parkinson's disease affecting more than dopaminergic neurons in the substantia nigra. |
1985-09-26 |
2023-08-11 |
Not clear |
| R B Innis, R Andrade, G K Aghajania. Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigra. Brain research. vol 335. issue 2. 1985-08-15. PMID:2408703. |
substance k excites dopaminergic and non-dopaminergic neurons in rat substantia nigra. |
1985-08-15 |
2023-08-11 |
rat |
| R B Innis, R Andrade, G K Aghajania. Substance K excites dopaminergic and non-dopaminergic neurons in rat substantia nigra. Brain research. vol 335. issue 2. 1985-08-15. PMID:2408703. |
sk microiontophoresed onto single units in the substantia nigra caused excitation of approximately 50% of both dopaminergic and non-dopaminergic neurons. |
1985-08-15 |
2023-08-11 |
rat |
| C J Phelps, J R Sladek, W W Morgan, A Bartk. Hypothalamic catecholamine histofluorescence in dwarf mice. Cell and tissue research. vol 240. issue 1. 1985-07-24. PMID:3995539. |
in supraoptic and paraventricular nuclei, and in the zona interna of the median eminence, ca fluorescence attributable to ne was comparable among dwarfs and normals; fluorescence of dopaminergic perikarya in substantia nigra was also unaffected in dwarfs. |
1985-07-24 |
2023-08-11 |
mouse |
| I Strömberg, S Johnson, B Hoffer, L Olso. Reinnervation of dopamine-denervated striatum by substantia nigra transplants: immunohistochemical and electrophysiological correlates. Neuroscience. vol 14. issue 4. 1985-07-23. PMID:2860618. |
this study evaluated whether or not fetal substantia nigra tissue, grafted to striatum previously lesioned with 6-hydroxydopamine, provides functional dopaminergic reinnervation of striatum. |
1985-07-23 |
2023-08-11 |
Not clear |
| G A Campbell, M J Eckardt, F F Weigh. Dopaminergic mechanisms in subthalamic nucleus of rat: analysis using horseradish peroxidase and microiontophoresis. Brain research. vol 333. issue 2. 1985-07-23. PMID:2986774. |
the observations of hrp-labelled neurons in the pars compacta region of substantia nigra following injection of hrp into the stn together with the da responsiveness of stn neurons suggest the possibility of a dopaminergic nigro-subthalamic pathway. |
1985-07-23 |
2023-08-11 |
rat |
| J S Hong, K Yoshikawa, T Kanamatsu, S L Sabo. Modulation of striatal enkephalinergic neurons by antipsychotic drugs. Federation proceedings. vol 44. issue 9. 1985-07-17. PMID:3838946. |
several lines of evidence, which showed that striatal levels of [met5]enkephalin (me) increase after the nigrostriatal dopaminergic pathway was interrupted by hemitransection or direct administration of 6-hydroxydopamine to the substantia nigra, or after repeated injections of either reserpine or haloperidol, suggest that dopamine (da) plays an important role in regulating the metabolism of me-containing neurons in the striatum. |
1985-07-17 |
2023-08-11 |
rat |
| C R Gallistel, Y Gomita, E Yadin, K A Campbel. Forebrain origins and terminations of the medial forebrain bundle metabolically activated by rewarding stimulation or by reward-blocking doses of pimozide. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 5. 1985-06-28. PMID:3873523. |
using longer pulse durations and/or shifting the site of stimulation to the substantia nigra activated many of the systems not activated in the first experiment, including all of the major dopaminergic projection systems, proving the capacity of the technique to reveal activation of these systems. |
1985-06-28 |
2023-08-11 |
Not clear |