| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pershia Samadi, Laurent Grégoire, Abdallah Hadj Tahar, Thérèse Di Paolo, Claude Rouillard, Paul J Bédar. Naltrexone in the short-term decreases antiparkinsonian response to l-Dopa and in the long-term increases dyskinesias in drug-naïve parkinsonian monkeys. Neuropharmacology. vol 49. issue 2. 2005-10-06. PMID:15996565. |
nigrostriatal dopaminergic denervation and levodopa therapy in animal models and in parkinsonian patients are associated with an enhanced opioid transmission in the striatum. |
2005-10-06 |
2023-08-12 |
human |
| Tetsuya Maeda, Ken Nagata, Yasuji Yoshida, Kazuya Kannar. Serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-DOPA. Brain research. vol 1046. issue 1-2. 2005-09-27. PMID:15894297. |
serotonergic hyperinnervation into the dopaminergic denervated striatum compensates for dopamine conversion from exogenously administered l-dopa. |
2005-09-27 |
2023-08-12 |
rat |
| Eun Kyoung Ryu, Yearn Seong Choe, Eun Young Park, Jin-Young Paik, Yu Ri Kim, Kyung-Han Lee, Yong Choi, Sang Eun Kim, Byung-Tae Ki. Synthesis and evaluation of 2-[18F]fluoro-CP-118,954 for the in vivo mapping of acetylcholinesterase. Nuclear medicine and biology. vol 32. issue 2. 2005-09-08. PMID:15721764. |
a high level of uptake in the striatum was also shown at all time points in the olfactory tubercle, which is known to have dopaminergic neurons. |
2005-09-08 |
2023-08-12 |
mouse |
| E A Del Bel, F S Guimarães, M Bermúdez-Echeverry, M Z Gomes, A Schiaveto-de-souza, F E Padovan-Neto, V Tumas, A P Barion-Cavalcanti, M Lazzarini, L P Nucci-da-Silva, D de Paula-Souz. Role of nitric oxide on motor behavior. Cellular and molecular neurobiology. vol 25. issue 2. 2005-09-01. PMID:16047547. |
considering these results we suggest that (i) no may modulate motor behavior, probably by interfering with dopaminergic, serotonergic, and cholinergic neurotransmission in the striatum; (ii) subchronic no synthesis inhibition induces plastic changes in no-producing neurons in brain areas related to motor control and causes cross-tolerance to the cataleptic effect of haloperidol, raising the possibility that such treatments could decrease motor side effects associated with antipsychotic medications. |
2005-09-01 |
2023-08-12 |
mouse |
| P Mohapel, H Frielingsdorf, J Häggblad, O Zachrisson, P Brundi. Platelet-derived growth factor (PDGF-BB) and brain-derived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions. Neuroscience. vol 132. issue 3. 2005-08-30. PMID:15837137. |
both in the striatum and in the substantia nigra there were no indications of any newly born cells differentiating into dopaminergic neurons following growth factor treatment, such that brdu-labeled cells never co-expressed tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis. |
2005-08-30 |
2023-08-12 |
rat |
| Monicque M Lorist, Maarten A S Boksem, K Richard Ridderinkho. Impaired cognitive control and reduced cingulate activity during mental fatigue. Brain research. Cognitive brain research. vol 24. issue 2. 2005-08-30. PMID:15993758. |
findings that (1) mental fatigue is associated with compromised performance monitoring and inadequate performance adjustments after errors, (2) monitoring functions of acc and striatum rely on dopaminergic inputs from the midbrain, and (3) patients with striatal dopamine deficiencies show symptomatic mental fatigue, suggest that mental fatigue results from a failure to maintain adequate levels of dopaminergic transmission to the striatum and the acc, resulting in impaired cognitive control. |
2005-08-30 |
2023-08-12 |
Not clear |
| Panagiotis Giompres, Foteini Deli. Dopamine transporters in the cerebellum of mutant mice. Cerebellum (London, England). vol 4. issue 2. 2005-08-30. PMID:16035192. |
however, recent evidence suggests that in the cerebellum there is a small dopaminergic element, whose properties are similar to the well characterized system of striatum. |
2005-08-30 |
2023-08-12 |
mouse |
| Olle Lindvall, Anders Björklun. Cell therapy in Parkinson's disease. NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics. vol 1. issue 4. 2005-08-23. PMID:15717042. |
the grafted dopaminergic neurons can reinnervate the denervated striatum, restore regulated dopamine (da) release and movement-related frontal cortical activation, and give rise to significant symptomatic relief. |
2005-08-23 |
2023-08-12 |
Not clear |
| V S Nascimento, A A Oliveira, R M Freitas, F C F Sousa, S M M Vasconcelos, G S B Viana, M M F Fontele. Pilocarpine-induced status epilepticus: monoamine level, muscarinic and dopaminergic receptors alterations in striatum of young rats. Neuroscience letters. vol 383. issue 1-2. 2005-08-22. PMID:15876489. |
pilocarpine-induced status epilepticus: monoamine level, muscarinic and dopaminergic receptors alterations in striatum of young rats. |
2005-08-22 |
2023-08-12 |
rat |
| V S Nascimento, A A Oliveira, R M Freitas, F C F Sousa, S M M Vasconcelos, G S B Viana, M M F Fontele. Pilocarpine-induced status epilepticus: monoamine level, muscarinic and dopaminergic receptors alterations in striatum of young rats. Neuroscience letters. vol 383. issue 1-2. 2005-08-22. PMID:15876489. |
behavioural changes, muscarinic and dopaminergic receptors density and levels of monoamines were measured in striatum of rats after pilocarpine-induced status epilepticus (se). |
2005-08-22 |
2023-08-12 |
rat |
| Yeung-Kee Kim, Hyung-Ho Lim, Yun-Kyung Song, Hee-Hyuk Lee, Sabina Lim, Seung-Moo Han, Chang-Ju Ki. Effect of acupuncture on 6-hydroxydopamine-induced nigrostratal dopaminergic neuronal cell death in rats. Neuroscience letters. vol 384. issue 1-2. 2005-08-22. PMID:15893426. |
immunostaining for tyrosine hydroxylase demonstrated a dopaminergic neuronal loss in the substantia nigra and dopaminergic fiber loss in the striatum. |
2005-08-22 |
2023-08-12 |
rat |
| L E Bartlett, I Mende. Dopaminergic reinnervation of the globus pallidus by fetal nigral grafts in the rodent model of Parkinson's disease. Cell transplantation. vol 14. issue 2-3. 2005-08-19. PMID:15881421. |
the current neural transplantation strategy for parkinson's disease (pd) involves the dopaminergic reinnervation of the striatum (str). |
2005-08-19 |
2023-08-12 |
rat |
| Ali Sajadi, Matthias Bauer, Beat Thöny, Patrick Aebische. Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production. Journal of neurochemistry. vol 93. issue 6. 2005-08-02. PMID:15935064. |
in order to elucidate gdnf-mediated biochemical effects on dopaminergic neurons, we overexpressed gdnf in the intact rat striatum using a lentiviral vector-mediated gene transfer technique. |
2005-08-02 |
2023-08-12 |
rat |
| Y Shirayama, K T Muneoka, M Iwata, H Ishida, G Hazama, R Kawahar. Pregnenolone and dehydroepiandrosterone administration in neonatal rats alters the immunoreactivity of hippocampal synapsin I, neuropeptide Y and glial fibrillary acidic protein at post-puberty. Neuroscience. vol 133. issue 1. 2005-08-01. PMID:15893638. |
in our previous study, pregnenolone administered to rats during the neonatal period altered adenosinergic and dopaminergic functions in the striatum and cerebral cortex. |
2005-08-01 |
2023-08-12 |
rat |
| S J López-Pérez, P Vergara, J P Ventura-Valenzuela, M E Ureña-Guerrero, J Segovia, C Beas-Zárat. Modification of dopaminergic markers expression in the striatum by neonatal exposure to glutamate during development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 23. issue 4. 2005-08-01. PMID:15927757. |
modification of dopaminergic markers expression in the striatum by neonatal exposure to glutamate during development. |
2005-08-01 |
2023-08-12 |
rat |
| S J López-Pérez, P Vergara, J P Ventura-Valenzuela, M E Ureña-Guerrero, J Segovia, C Beas-Zárat. Modification of dopaminergic markers expression in the striatum by neonatal exposure to glutamate during development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 23. issue 4. 2005-08-01. PMID:15927757. |
results indicate that an over-stimulation of the glutamatergic system by neonatal exposure to a high glutamate concentration induces a partial loss in th-positive neurons in the sn and an important reduction in dopaminergic markers expression in the striatum, suggesting that early excitotoxicity could contribute to developmental alterations in the nigrostriatal pathway, which may be associated with various disorders of the basal ganglia. |
2005-08-01 |
2023-08-12 |
rat |
| Susana Pezzi, Nuria Checa, Jordi Alberc. The vulnerability of striatal projection neurons and interneurons to excitotoxicity is differentially regulated by dopamine during development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 23. issue 4. 2005-08-01. PMID:15927758. |
in the present work, we have analyzed the modulation of striatum vulnerability to quinolinate (quin)-induced excitotoxicity in different neuronal populations by the nigrostriatal dopaminergic pathway during postnatal development. |
2005-08-01 |
2023-08-12 |
Not clear |
| Stathis Bekris, Katerina Antoniou, Spyros Daskas, Zeta Papadopoulou-Daifot. Behavioural and neurochemical effects induced by chronic mild stress applied to two different rat strains. Behavioural brain research. vol 161. issue 1. 2005-07-29. PMID:15904709. |
in the present study, cms-induced behavioural responses along with neurochemical alterations in dopaminergic and serotonergic function in prefrontal cortex, striatum, hypothalamus and hippocampus were examined following treatment with imipramine in wistar and sprague-dawley rats. |
2005-07-29 |
2023-08-12 |
rat |
| Serge Przedborsk. Pathogenesis of nigral cell death in Parkinson's disease. Parkinsonism & related disorders. vol 11 Suppl 1. 2005-07-25. PMID:15885625. |
the fate of dopaminergic neurons in pd may also be influenced by additional factors such as excitotoxicity, emanating from the increased glutamatergic input from the subthalamic nucleus to the substantia nigra, and the glial response that arises in the striatum and the substantia nigra. |
2005-07-25 |
2023-08-12 |
Not clear |
| Andreas Hald, Julie Lothariu. Oxidative stress and inflammation in Parkinson's disease: is there a causal link? Experimental neurology. vol 193. issue 2. 2005-07-15. PMID:15869932. |
not only have activated microglia and increased levels of inflammatory mediators been detected in the striatum of deceased pd patients, but a large body of animal studies points to a contributory role of inflammation in dopaminergic cell loss. |
2005-07-15 |
2023-08-12 |
human |