| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Theodore, W A Cass, W F Marago. Methamphetamine and human immunodeficiency virus protein Tat synergize to destroy dopaminergic terminals in the rat striatum. Neuroscience. vol 137. issue 3. 2006-04-12. PMID:16338084. |
dysfunction of the dopaminergic system accompanied by loss of dopamine in the striatum is a major feature of human immunodeficiency virus-1-associated dementia. |
2006-04-12 |
2023-08-12 |
human |
| S Theodore, W A Cass, W F Marago. Methamphetamine and human immunodeficiency virus protein Tat synergize to destroy dopaminergic terminals in the rat striatum. Neuroscience. vol 137. issue 3. 2006-04-12. PMID:16338084. |
the results indicate that methamphetamine and tat interact to produce an enhanced injury to dopaminergic nerve terminals in the striatum with sparing of the substantia nigra by a mechanism involving oxidative stress. |
2006-04-12 |
2023-08-12 |
human |
| Fabio Fumagalli, Laura Pasquale, Giorgio Racagni, Marco Andrea Riv. Dynamic regulation of fibroblast growth factor 2 (FGF-2) gene expression in the rat brain following single and repeated cocaine administration. Journal of neurochemistry. vol 96. issue 4. 2006-04-06. PMID:16412094. |
here, we demonstrate that a single cocaine injection selectively up-regulated fibroblast growth factor 2 (fgf-2) mrna levels in the striatum and prefrontal cortex within 2 h, an effect that vanished by 24 h. however, prolonged exposure (5 or 14 days) to cocaine treatment produced an enduring elevation of fgf-2 mrna levels that was evident 72 h after the last injection in the prefrontal cortex and could even persist for 14 days in the striatum, raising the possibility that cocaine treatment primes the brain, resulting in longer-lasting fgf-2 up-regulation in regions that are highly innervated by dopaminergic projections. |
2006-04-06 |
2023-08-12 |
rat |
| Patricia Rojas, Javier E Franco-Pérez, Carolina Rojas, Julio Rojas-Castañeda, Manuchair Ebadi, Francisca Fernández-Valverde, Norma Serrano-Garcí. Reduction of zinc-positive terminal fields in striatum of mouse after 1-methyl-4-phenylpyridinium neurotoxicity. Neurotoxicology. vol 26. issue 6. 2006-04-05. PMID:15950287. |
the decrease of zinc-positive neuronal terminal fields in the striatum after mpp+ administration is most likely due to a neuronal release of vesicular zinc in response to its dopaminergic neurotoxicity. |
2006-04-05 |
2023-08-12 |
mouse |
| Jun Lu, Thomas C Jhou, Clifford B Sape. Identification of wake-active dopaminergic neurons in the ventral periaqueductal gray matter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 1. 2006-03-31. PMID:16399687. |
it is sometimes assumed that the dopaminergic neurons in the ventral tegmental area that project to the prefrontal cortex and striatum may regulate the state of arousal; however, the firing of these dopaminergic neurons does not correlate with overall levels of behavioral wakefulness. |
2006-03-31 |
2023-08-12 |
rat |
| M V Retiunskaia, V S Kudrin, P M Klodt, K S Us, T A Gudasheva, R U Ostrovskai. [The new tripeptoid neurotensin analog dilept selectively affects dopamine turnover in nucleus accumbens and hypothalamus]. Eksperimental'naia i klinicheskaia farmakologiia. vol 68. issue 6. 2006-03-30. PMID:16405028. |
the selective influence of dilept on the dopaminergic system activity in nucleus accumbens (but not in striatum), together with the previously obtained behavioral data, suggest that dilept is a new atypical neuroleptic producing no extrapyramidal side effects. |
2006-03-30 |
2023-08-12 |
rat |
| Renee M Miller, Gretchen L Kiser, T M Kaysser-Kranich, Randall J Lockner, Chockalingam Palaniappan, Howard J Federof. Robust dysregulation of gene expression in substantia nigra and striatum in Parkinson's disease. Neurobiology of disease. vol 21. issue 2. 2006-03-29. PMID:16143538. |
we hypothesize that specific differential gene expression underlies important pathogenic processes in parkinson's disease, which is characterized by the gradual loss of dopaminergic neurons in the substantia nigra and consequent loss of dopamine in the striatum. |
2006-03-29 |
2023-08-12 |
human |
| Caroline F Zink, Giuseppe Pagnoni, Jonathan Chappelow, Megan Martin-Skurski, Gregory S Bern. Human striatal activation reflects degree of stimulus saliency. NeuroImage. vol 29. issue 3. 2006-03-29. PMID:16153860. |
although the striatum and its dopaminergic inputs respond to a variety of stimuli categorically defined as salient, including rewards, the relationship between striatal activity and saliency is not well understood. |
2006-03-29 |
2023-08-12 |
human |
| Michelle Day, Zhongfeng Wang, Jun Ding, Xinhai An, Cali A Ingham, Andrew F Shering, David Wokosin, Ema Ilijic, Zhuoxin Sun, Allan R Sampson, Enrico Mugnaini, Ariel Y Deutch, Susan R Sesack, Gordon W Arbuthnott, D James Surmeie. Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models. Nature neuroscience. vol 9. issue 2. 2006-03-29. PMID:16415865. |
although it is known that dopaminergic neurons that innervate the striatum die in parkinson disease, it is not clear how this loss leads to symptoms. |
2006-03-29 |
2023-08-12 |
Not clear |
| Elena H Chartoff, Mark S Szczypka, Richard D Palmiter, Daniel M Dors. Endogenous neurotensin attenuates dopamine-dependent locomotion and stereotypy. Brain research. vol 1022. issue 1-2. 2006-03-23. PMID:15353215. |
the neuropeptide neurotensin (nt) is highly sensitive to changes in dopaminergic signaling in the striatum, and is thought to modulate dopamine-mediated behaviors. |
2006-03-23 |
2023-08-12 |
mouse |
| Jun Huang, Huaqing Liu, Wangwen Gu, Zhou Yan, Zhenghong Xu, Yongxin Yang, Xingzu Zhu, Yaping L. A delivery strategy for rotenone microspheres in an animal model of Parkinson's disease. Biomaterials. vol 27. issue 6. 2006-03-21. PMID:16118017. |
the rotenone microspheres (9 mg/kg) produced typical pd symptoms in rats, for example, the cataleptic behavior test demonstrated a obviously prolonged descent latency compared with control animals after administration, and the tyrosine hydroxylase (th) immunohistochemistry tests showed typical histological evidence of selective degeneration of the nigrostriatal dopaminergic system (striatum and substantia nigra) in rotenone microspheres-treated rats. |
2006-03-21 |
2023-08-12 |
rat |
| Takashi Yamada, Takehiko Terashima, Tsutomu Okubo, Lekh Raj Juneja, Hidehiko Yokogosh. Effects of theanine, r-glutamylethylamide, on neurotransmitter release and its relationship with glutamic acid neurotransmission. Nutritional neuroscience. vol 8. issue 4. 2006-03-16. PMID:16493792. |
l-trans-2,4-pdc or theanine perfusion into the brain striatum caused dopamine release from dopaminergic neurons. |
2006-03-16 |
2023-08-12 |
rat |
| Daphne M Hasbani, Francisco A Perez, Richard D Palmiter, Karen L O'Malle. Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 41. 2006-03-13. PMID:16221852. |
in contrast to in vitro results, genetic or pharmacologic da depletion did not attenuate loss of dopaminergic neurons in the sn or dopaminergic neuron terminals in the striatum. |
2006-03-13 |
2023-08-12 |
mouse |
| Geraldine J Kress, Ian J Reynold. Dopaminergic neurotoxins require excitotoxic stimulation in organotypic cultures. Neurobiology of disease. vol 20. issue 3. 2006-03-09. PMID:15996475. |
we have investigated the properties of the dopaminergic neurotoxins 6-hydroxydopamine, 1-methyl-4-phenylpyridinium and rotenone using an organotypic culture that included slices of substantia nigra, striatum and cortex maintained for about 20 days in vitro. |
2006-03-09 |
2023-08-12 |
Not clear |
| Mar Cuadrado-Tejedor, M Teresa Sesma, José Manuel Giménez-Amaya, Lourdes Orti. Changes in cytoskeletal gene expression linked to MPTP-treatment in Mice. Neurobiology of disease. vol 20. issue 3. 2006-03-09. PMID:16005240. |
parkinson's disease is a neurodegenerative disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra and a marked reduction of dopamine (da) levels in the striatum. |
2006-03-09 |
2023-08-12 |
mouse |
| Lachlan Thompson, Perrine Barraud, Elin Andersson, Deniz Kirik, Anders Björklun. Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000637. |
by retrograde axonal tracing, we show that dopaminergic innervation of the striatum is derived almost exclusively from the girk2-positive snpc cells, whereas the calbindin-positive vta neurons project to the frontal cortex and probably also other forebrain areas. |
2006-02-28 |
2023-08-12 |
mouse |
| Zoe Puschban, Nadia Stefanova, Asa Petersén, Christian Winkler, Patrik Brundin, Werner Poewe, Gregor K Wennin. Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy. Brain research bulletin. vol 68. issue 1-2. 2006-02-15. PMID:16325004. |
analysis of embryonic mesencephalic grafts revealed survival of dopaminergic neurons and outgrowth of fibres re-innervating the adult striatum. |
2006-02-15 |
2023-08-12 |
rat |
| Ryuji Kaji, Satoshi Goto, Gen Tamiya, L V Le. [Molecular and anatomical bases of dystonia: X-linked recessive dystonia-parkinsonism (DYT3)]. Rinsho shinkeigaku = Clinical neurology. vol 45. issue 11. 2006-02-15. PMID:16447732. |
because striosomal neurons inhibit nigrostriatal dopaminergic neurons via gabaergic innervation, the striosomal lesion could account for dopamine excess in the striatum, which in turn causes a hyperkinetic state or dystonia. |
2006-02-15 |
2023-08-12 |
Not clear |
| Shin-ichi Muramats. [Gene therapy and cell transplantation for Parkinson's disease]. Rinsho shinkeigaku = Clinical neurology. vol 45. issue 11. 2006-02-15. PMID:16447758. |
in most cases, dopaminergic cells are transplanted ectopically into the striatum instead of the substantia nigra. |
2006-02-15 |
2023-08-12 |
Not clear |
| S M Smits, S van der Nobelen, K J M Hornman, L von Oerthel, J P H Burbach, M P Smid. Signalling through phospholipase C beta 4 is not essential for midbrain dopaminergic neuron survival. Neuroscience. vol 136. issue 1. 2006-02-14. PMID:16198487. |
furthermore, we report here a normal distribution of midbrain dopaminergic cell bodies and axonal projection to the striatum in phospholipase c beta 4-/- mice, indicating that signaling of phospholipase c beta 4 is not essential for the survival of midbrain dopaminergic neurons. |
2006-02-14 |
2023-08-12 |
mouse |