| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lachlan Thompson, Perrine Barraud, Elin Andersson, Deniz Kirik, Anders Björklun. Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 27. 2006-02-28. PMID:16000637. |
by retrograde axonal tracing, we show that dopaminergic innervation of the striatum is derived almost exclusively from the girk2-positive snpc cells, whereas the calbindin-positive vta neurons project to the frontal cortex and probably also other forebrain areas. |
2006-02-28 |
2023-08-12 |
mouse |
| Zoe Puschban, Nadia Stefanova, Asa Petersén, Christian Winkler, Patrik Brundin, Werner Poewe, Gregor K Wennin. Evidence for dopaminergic re-innervation by embryonic allografts in an optimized rat model of the Parkinsonian variant of multiple system atrophy. Brain research bulletin. vol 68. issue 1-2. 2006-02-15. PMID:16325004. |
analysis of embryonic mesencephalic grafts revealed survival of dopaminergic neurons and outgrowth of fibres re-innervating the adult striatum. |
2006-02-15 |
2023-08-12 |
rat |
| Ryuji Kaji, Satoshi Goto, Gen Tamiya, L V Le. [Molecular and anatomical bases of dystonia: X-linked recessive dystonia-parkinsonism (DYT3)]. Rinsho shinkeigaku = Clinical neurology. vol 45. issue 11. 2006-02-15. PMID:16447732. |
because striosomal neurons inhibit nigrostriatal dopaminergic neurons via gabaergic innervation, the striosomal lesion could account for dopamine excess in the striatum, which in turn causes a hyperkinetic state or dystonia. |
2006-02-15 |
2023-08-12 |
Not clear |
| Shin-ichi Muramats. [Gene therapy and cell transplantation for Parkinson's disease]. Rinsho shinkeigaku = Clinical neurology. vol 45. issue 11. 2006-02-15. PMID:16447758. |
in most cases, dopaminergic cells are transplanted ectopically into the striatum instead of the substantia nigra. |
2006-02-15 |
2023-08-12 |
Not clear |
| S M Smits, S van der Nobelen, K J M Hornman, L von Oerthel, J P H Burbach, M P Smid. Signalling through phospholipase C beta 4 is not essential for midbrain dopaminergic neuron survival. Neuroscience. vol 136. issue 1. 2006-02-14. PMID:16198487. |
furthermore, we report here a normal distribution of midbrain dopaminergic cell bodies and axonal projection to the striatum in phospholipase c beta 4-/- mice, indicating that signaling of phospholipase c beta 4 is not essential for the survival of midbrain dopaminergic neurons. |
2006-02-14 |
2023-08-12 |
mouse |
| Toshio Obat. Allopurinol suppresses 2-bromoethylamine and 1-methyl-4-phenylpyridinium ion (MPP(+))-induced hydroxyl radical generation in rat striatum. Toxicology. vol 218. issue 1. 2006-02-13. PMID:16271280. |
the present study was examined whether or not 2-bromoethyamine, a semicarbazide-sensitive amine oxidase (ssao, ec; 1.4.3.6) inhibitor, would increase an active dopaminergic neurotoxin, 1-methyl-4-phenylpyridinium ion (mpp(+))-induced hydroxyl radical ((*)oh) generation in the rat striatum. |
2006-02-13 |
2023-08-12 |
rat |
| Cecilia Ericson, Biljana Georgievska, Cecilia Lundber. Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease. The European journal of neuroscience. vol 22. issue 11. 2006-02-07. PMID:16324109. |
intact animals receiving transplants of gdnf-transduced astrocytes displayed an increased contralateral turning (5.39 +/- 1.19 turns/min) in the amphetamine-induced rotation test, which significantly correlated with the gdnf tissue levels measured in the striatum, indicating a stimulatory effect of gdnf on the dopaminergic function. |
2006-02-07 |
2023-08-12 |
rat |
| Cecilia Ericson, Biljana Georgievska, Cecilia Lundber. Ex vivo gene delivery of GDNF using primary astrocytes transduced with a lentiviral vector provides neuroprotection in a rat model of Parkinson's disease. The European journal of neuroscience. vol 22. issue 11. 2006-02-07. PMID:16324109. |
by contrast, when the cells were transplanted to the striatum, the level of released gdnf was not sufficient to rescue the striatal fibers and, hence, to protect the nigral dopaminergic neurons. |
2006-02-07 |
2023-08-12 |
rat |
| Ryuji Kaji, Satoshi Goto, Gen Tamiya, Satoshi Ando, Satoshi Makino, L V Le. Molecular dissection and anatomical basis of dystonia: X-linked recessive dystonia-parkinsonism (DYT3). The journal of medical investigation : JMI. vol 52 Suppl. 2006-02-03. PMID:16366515. |
because striosomal neurons inhibit nigrostriatal dopaminergic neurons via gabaergic innervation, the striosomal lesion could account for dopamine excess in the striatum, which in turn causes a hyperkinetic state or dystonia. |
2006-02-03 |
2023-08-12 |
Not clear |
| Barry J Everitt, Trevor W Robbin. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nature neuroscience. vol 8. issue 11. 2006-01-25. PMID:16251991. |
we hypothesize that the change from voluntary drug use to more habitual and compulsive drug use represents a transition at the neural level from prefrontal cortical to striatal control over drug seeking and drug taking behavior as well as a progression from ventral to more dorsal domains of the striatum, involving its dopaminergic innervation. |
2006-01-25 |
2023-08-12 |
Not clear |
| Michel St-Hilaire, Eric Landry, Daniel Lévesque, Claude Rouillar. Denervation and repeated L-DOPA induce complex regulatory changes in neurochemical phenotypes of striatal neurons: implication of a dopamine D1-dependent mechanism. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:15896973. |
we looked at the territorial patterns of expression of neurotensin (nt), dynorphin (dyn), enkephalin (enk) and nur77 (also known as ngfi-b) mrna expression in the striatum and contrasted these with markers of glutamatergic transport and dopaminergic receptor functions. |
2006-01-23 |
2023-08-12 |
rat |
| Rocío M de Pablos, Antonio J Herrera, Mayka Tomás-Camardiel, Alberto Machado, Josefina Can. Deprenyl enhances the striatal neuronal damage produced by quinolinic acid. Brain research. Molecular brain research. vol 141. issue 1. 2006-01-23. PMID:16202473. |
these effects are produced by deprenyl potentiation of dopamine actions since dopamine depletion produced by previous injection of the dopaminergic toxin 6-hydroxydopamine within the medial forebrain bundle overcomes deprenyl effects and the involvement of dopamine in the quinolinic acid-induced toxicity in striatum. |
2006-01-23 |
2023-08-12 |
Not clear |
| b' Leonid Yavich, Mari Oksman, Heikki Tanila, Petri Kerokoski, Mikko Hiltunen, Thomas van Groen, Jukka Puoliv\\xc3\\xa4li, Pekka T M\\xc3\\xa4nnist\\xc3\\xb6, Arturo Garc\\xc3\\xada-Horsman, Ewen MacDonald, Konrad Beyreuther, Tobias Hartmann, Pekka J\\xc3\\xa4k\\xc3\\xa4l\\xc3\\xa. Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein. Neurobiology of disease. vol 20. issue 2. 2006-01-23. PMID:16242637.' |
in vivo voltammetry showed that a30p mice responded to longer stimulation of the ascending dopaminergic pathways with less dopamine release in striatum and had a slower rate of dopamine decline after repeated stimulations or after alpha-methyl-p-tyrosine-hcl treatment. |
2006-01-23 |
2023-08-12 |
mouse |
| Hongwen Zhu, MoonSook Lee, Fangxia Guan, Soh Agatsuma, Daniel Scott, Kevin Fabrizio, Allen A Fienberg, Noboru Hiro. DARPP-32 phosphorylation opposes the behavioral effects of nicotine. Biological psychiatry. vol 58. issue 12. 2006-01-20. PMID:16084497. |
the addictive properties of nicotine are mediated via dopaminergic pathways and their post-synaptic neurons in the striatum. |
2006-01-20 |
2023-08-12 |
Not clear |
| Christopher J MacDonald, Warren H Mec. Differential effects of clozapine and haloperidol on interval timing in the supraseconds range. Psychopharmacology. vol 182. issue 2. 2006-01-18. PMID:16001114. |
these results support the proposal that typical antipsychotic drugs such as haloperidol and atypical antipsychotic drugs such as clozapine exert differential effects on dopaminergic, serotonergic, and glutamatergic systems within the cortex and striatum, two brain regions shown to be crucial for interval timing. |
2006-01-18 |
2023-08-12 |
rat |
| Miho Hamada, Joseph P Hendrick, Gregory R Ryan, Mahomi Kuroiwa, Hideho Higashi, Masatoshi Tanaka, Angus C Nairn, Paul Greengard, Akinori Nish. Nicotine regulates DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of 32 kDa) phosphorylation at multiple sites in neostriatal neurons. The Journal of pharmacology and experimental therapeutics. vol 315. issue 2. 2006-01-12. PMID:16040813. |
nicotinic acetylcholine receptors (nachrs) regulate dopaminergic signaling in the striatum by modulating the release of neurotransmitters. |
2006-01-12 |
2023-08-12 |
Not clear |
| W A Cass, M W Manning, S L Baile. Restorative effects of GDNF on striatal dopamine release in rats treated with neurotoxic doses of methamphetamine. Annals of the New York Academy of Sciences. vol 914. 2006-01-04. PMID:11085315. |
these results suggest that gdnf can accelerate recovery of dopaminergic release processes in the striatum of rats treated with neurotoxic doses of meth. |
2006-01-04 |
2023-08-12 |
rat |
| C Buhmann, F Binkofski, C Klein, C Büchel, T van Eimeren, C Erdmann, K Hedrich, M Kasten, J Hagenah, G Deuschl, P P Pramstaller, H R Siebne. Motor reorganization in asymptomatic carriers of a single mutant Parkin allele: a human model for presymptomatic parkinsonism. Brain : a journal of neurology. vol 128. issue Pt 10. 2005-12-29. PMID:15947065. |
it has been shown that asymptomatic carriers with a single mutant allele have latent presynaptic dopaminergic dysfunction in the striatum. |
2005-12-29 |
2023-08-12 |
human |
| Hans C Lou, Markus Nowak, Troels W Kjae. The mental self. Progress in brain research. vol 150. 2005-12-22. PMID:16186024. |
the inclusion of the striatum and our subsequent finding of increased striatal dopamine binding to d2 receptors during meditation suggested dopaminergic regulation of this circuit. |
2005-12-22 |
2023-08-12 |
Not clear |
| Yoko Matsuoka, Tomoyuki Furuyashiki, Kiyofumi Yamada, Taku Nagai, Haruhiko Bito, Yasuhiro Tanaka, Shiho Kitaoka, Fumitaka Ushikubi, Toshitaka Nabeshima, Shuh Narumiy. Prostaglandin E receptor EP1 controls impulsive behavior under stress. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 44. 2005-12-21. PMID:16247016. |
dopamine turnover in the frontal cortex and striatum was increased in ptger1(-/-) mice, and administration of dopaminergic antagonists corrected their behavioral phenotype. |
2005-12-21 |
2023-08-12 |
mouse |