| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel Alvarez-Fischer, Carmen Henze, Corinna Strenzke, Jan Westrich, Boris Ferger, Günter U Höglinger, Wolfgang H Oertel, Andreas Hartman. Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice. Experimental neurology. vol 210. issue 1. 2008-05-02. PMID:18053987. |
the aim of the present study was to characterize the time course of intra-striatal 6-ohda lesions in mice with regard to i) dopaminergic cell loss, ii) dopamine concentrations in the substantia nigra and the striatum, iii) hydroxylation products in substantia nigra and striatum and iv) behavioural impairment. |
2008-05-02 |
2023-08-12 |
mouse |
| Beate Winner, Sebastien Couillard-Despres, Martin Geyer, Robert Aigner, Ulrich Bogdahn, Ludwig Aigner, H Georg Kuhn, Jürgen Winkle. Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration. Journal of neuropathology and experimental neurology. vol 67. issue 2. 2008-05-02. PMID:18219258. |
these growth factors also increased dopaminergic neurogenesis in the olfactory bulb and promoted the migration of newly generated neuroblasts from the subventricular zone into the adjacent striatum. |
2008-05-02 |
2023-08-12 |
Not clear |
| Beate Winner, Sebastien Couillard-Despres, Martin Geyer, Robert Aigner, Ulrich Bogdahn, Ludwig Aigner, H Georg Kuhn, Jürgen Winkle. Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration. Journal of neuropathology and experimental neurology. vol 67. issue 2. 2008-05-02. PMID:18219258. |
these findings suggest that newly generated neuroblasts may be redirected to the region of dopaminergic deficit, and that egf and fgf-2 can enhance dopaminergic neurogenesis in the olfactory bulb but not in the striatum. |
2008-05-02 |
2023-08-12 |
Not clear |
| David Belin, Barry J Everit. Cocaine seeking habits depend upon dopamine-dependent serial connectivity linking the ventral with the dorsal striatum. Neuron. vol 57. issue 3. 2008-05-02. PMID:18255035. |
these data thereby define the importance of interactions between ventral and dorsal domains of the striatum, mediated by dopaminergic transmission, in the neural mechanisms underlying the development and performance of cocaine-seeking habits that are a key characteristic of drug addiction. |
2008-05-02 |
2023-08-12 |
rat |
| R Exley, S J Crag. Presynaptic nicotinic receptors: a dynamic and diverse cholinergic filter of striatal dopamine neurotransmission. British journal of pharmacology. vol 153 Suppl 1. 2008-04-28. PMID:18037926. |
only recently however, has the influence of presynaptic nicotinic receptors (nachrs) on dopaminergic axon terminals within striatum begun to be understood. |
2008-04-28 |
2023-08-12 |
Not clear |
| Jayanth S Chandran, Xian Lin, Agustin Zapata, Ahmet Höke, Mika Shimoji, Shonagh O'Leary Moore, Matthew P Galloway, Fiona M Laird, Philip C Wong, Donald L Price, Kathleen R Bailey, Jacqueline N Crawley, Toni Shippenberg, Huaibin Ca. Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function. Neurobiology of disease. vol 29. issue 3. 2008-04-28. PMID:18187333. |
the basal level of extracellular dopamine, evoked dopamine release and dopamine receptor d2 sensitivity appeared normal in the striatum of dj-1(-/-) mice, which was consistent with similar results between dj-1(-/-) and controls in behavioral paradigms specific for the dopaminergic system. |
2008-04-28 |
2023-08-12 |
mouse |
| B Galan-Rodriguez, A del-Marco, J A Flores, S Ramiro-Fuentes, R Gonzalez-Aparicio, I Tunez, I Tasset, E Fernandez-Espej. Grafts of extra-adrenal chromaffin cells as aggregates show better survival rate and regenerative effects on parkinsonian rats than dispersed cell grafts. Neurobiology of disease. vol 29. issue 3. 2008-04-28. PMID:18206378. |
sprouting of spared dopaminergic fibers within the striatum, reduction of dopamine axon degeneration, and/or enhanced phenotypic expression of th would explain striatal regeneration. |
2008-04-28 |
2023-08-12 |
rat |
| Francesco Errico, Emanuela Santini, Sara Migliarini, Anders Borgkvist, Diego Centonze, Valentina Nasti, Manolo Carta, Valentina De Chiara, Chiara Prosperetti, Daniela Spano, Denis Herve, Massimo Pasqualetti, Roberto Di Lauro, Gilberto Fisone, Alessandro Usiell. The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons. Molecular and cellular neurosciences. vol 37. issue 2. 2008-04-25. PMID:18035555. |
altogether, our results indicate that rhes is an important modulator of dopaminergic transmission in the striatum. |
2008-04-25 |
2023-08-12 |
mouse |
| Dieter Scheller, Christine Stichel-Gunkel, Hermann Lübbert, Gregory Porras, Paula Ravenscroft, Michael Hill, Erwan Bezar. Neuroprotective effects of rotigotine in the acute MPTP-lesioned mouse model of Parkinson's disease. Neuroscience letters. vol 432. issue 1. 2008-04-24. PMID:18162314. |
the study was designed to assess the neuroprotective potential of the d(3)/d(2)/d(1) dopamine receptor agonist rotigotine in the acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned (mptp) mouse model of parkinson's disease by measuring mesencephalic degenerating neurons using fluorojade staining and the remaining dopaminergic nerve endings in the striatum using dopamine transporter binding. |
2008-04-24 |
2023-08-12 |
mouse |
| Po See Chen, Yen Kuang Yang, Tzung Lieh Yeh, I-Hui Lee, Wei Jen Yao, Nan Tsing Chiu, Ru Band L. Correlation between body mass index and striatal dopamine transporter availability in healthy volunteers--a SPECT study. NeuroImage. vol 40. issue 1. 2008-04-23. PMID:18096411. |
recent lines of research suggest that, in addition to hypothalamic sites, the striatum dopaminergic system may be a target for regulating homeostasis that may be represented by the body mass index (bmi). |
2008-04-23 |
2023-08-12 |
human |
| Philippe Huot, Martin Lévesque, Marc Morissette, Frédéric Calon, Mehdi Dridi, Thérèse Di Paolo, André Paren. L-Dopa treatment abolishes the numerical increase in striatal dopaminergic neurons in parkinsonian monkeys. Journal of chemical neuroanatomy. vol 35. issue 1. 2008-04-22. PMID:17706922. |
the striatum harbors a population of dopaminergic interneurons that increases in number in animal models of parkinson's disease (pd), presumably to compensate for dopamine (da) depletion. |
2008-04-22 |
2023-08-12 |
monkey |
| Oliver D Howes, Andrew J Montgomery, Marie-Claude Asselin, Robin M Murray, Paul M Grasby, Philip K McGuir. Molecular imaging studies of the striatal dopaminergic system in psychosis and predictions for the prodromal phase of psychosis. The British journal of psychiatry. Supplement. vol 51. 2008-04-21. PMID:18055930. |
we selectively review the molecular imaging studies of the striatal dopaminergic system in psychosis and link this to models of psychosis and the functional subdivisions of the striatum to make predictions for the dopaminergic system in the prodromal phase of psychosis. |
2008-04-21 |
2023-08-12 |
Not clear |
| G K Murray, P R Corlett, L Clark, M Pessiglione, A D Blackwell, G Honey, P B Jones, E T Bullmore, T W Robbins, P C Fletche. Substantia nigra/ventral tegmental reward prediction error disruption in psychosis. Molecular psychiatry. vol 13. issue 3. 2008-04-17. PMID:17684497. |
we observed that patients with psychosis exhibit abnormal physiological responses associated with reward prediction error in the dopaminergic midbrain, striatum and limbic system, and we demonstrated subtle abnormalities in the ability of psychosis patients to discriminate between motivationally salient and neutral stimuli. |
2008-04-17 |
2023-08-12 |
human |
| Ewa Bałkowiec-Iskra, Iwona Kurkowska-Jastrzebska, Ilona Joniec, Agnieszka Ciesielska, Anna Członkowska, Andrzej Członkowsk. Dopamine, serotonin and noradrenaline changes in the striatum of C57BL mice following myelin oligodendrocyte glycoprotein (MOG) 35-55 and complete Freund adjuvant (CFA) administration. Acta neurobiologiae experimentalis. vol 67. issue 4. 2008-04-09. PMID:18320716. |
we have previously shown that induction of inflammatory reaction, both before and after injury of the striatum, affects regeneration of dopaminergic neurons. |
2008-04-09 |
2023-08-12 |
mouse |
| Christian Beste, Carsten Saft, Carsten Konrad, Jürgen Andrich, Anne Habbel, Inga Schepers, Andreas Jansen, Bettina Pfleiderer, Michael Falkenstei. Levels of error processing in Huntington's disease: a combined study using event-related potentials and voxel-based morphometry. Human brain mapping. vol 29. issue 2. 2008-04-08. PMID:17497629. |
huntington's disease (hd) is a neurogenetic disorder accompanied by an atrophy of the striatum and hence of the dopaminergic (da) system. |
2008-04-08 |
2023-08-12 |
Not clear |
| X Zhang, F Dong, G E Mayer, D C Bruch, J Ren, B Culve. Selective inhibition of cyclooxygenase-2 exacerbates methamphetamine-induced dopamine depletion in the striatum in rats. Neuroscience. vol 150. issue 4. 2008-04-08. PMID:17988800. |
the present study was designed to investigate the impact of acute methamphetamine (ma) administration on cox expression and prostaglandin e2 (pge(2)) production, and to evaluate the effect of selective cox-2 inhibition using celecoxib in ma-induced degeneration of dopaminergic terminal and cell apoptosis in the striatum. |
2008-04-08 |
2023-08-12 |
rat |
| K Antoniou, G Papathanasiou, E Papalexi, T Hyphantis, G G Nomikos, C Spyraki, Z Papadopoulou-Daifot. Individual responses to novelty are associated with differences in behavioral and neurochemical profiles. Behavioural brain research. vol 187. issue 2. 2008-04-07. PMID:18036673. |
neurochemical findings revealed distinct differences in serotonergic and dopaminergic activity in the striatum and the prefrontal cortex of hr as compared to lr rats. |
2008-04-07 |
2023-08-12 |
rat |
| Takashi Kat. [Evaluation of dopaminergic presynaptic function by [F-18] DOPA PET]. Rinsho shinkeigaku = Clinical neurology. vol 47. issue 11. 2008-04-04. PMID:18210809. |
dopaminergic functions in the extrastriatal area in addition to the striatum in vivo have been visualized with the combination of [f-18] dopa pet and statistical image analyses. |
2008-04-04 |
2023-08-12 |
Not clear |
| Nobukatsu Sawamot. [Functional mapping of dopaminergic transmission]. Rinsho shinkeigaku = Clinical neurology. vol 47. issue 11. 2008-04-04. PMID:18210810. |
d2 receptor antagonist 11c-raclopride (rac) with positron emission tomography (pet) now provides an in vivo approach for investigating dopaminergic transmission by monitoring changes in synaptic dopamine levels during task performance, our rac pet study suggests that the capacity to release dopamine during a working memory task is impaired in the striatum but relatively preserved in the medial prefrontal cortex in patients with pd. |
2008-04-04 |
2023-08-12 |
Not clear |
| Xiaoqun Zhang, Per E Andren, Paul Greengard, Per Svenningsso. Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 6. 2008-03-31. PMID:18256188. |
parkinson's disease (pd) is characterized by a progressive degeneration of substantia nigra dopaminergic neurons projecting to the striatum. |
2008-03-31 |
2023-08-12 |
mouse |