| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M P Martres, N Sales, M L Bouthenet, J C Schwart. Localisation and pharmacological characterisation of D-2 dopamine receptors in rat cerebral neocortex and cerebellum using [125I]iodosulpride. European journal of pharmacology. vol 118. issue 3. 1986-03-05. PMID:2935411. |
the ic50 values of a large variety of dopaminergic and non-dopaminergic agents against [125i]iodosulpride binding in parietal cortex or cerebellum were highly correlated with their ic50 values against [125i]iodosulpride (or [3h]domperidone) binding in striatum. |
1986-03-05 |
2023-08-11 |
rat |
| K R Carlson, D O Coope. Morphine dependence and protracted abstinence: regional alterations in CNS radioligand binding. Pharmacology, biochemistry, and behavior. vol 23. issue 6. 1986-02-19. PMID:3001786. |
binding assays for alpha-2 adrenergic sites (3h-clonidine), beta-1/beta-2 adrenergic sites (3h-dihydroalprenolol), and dopaminergic (d2)/serotonergic (5-ht2) sites (3h-spiroperidol) were performed on tissue from frontal cortex, hippocampus, striatum, and brainstem. |
1986-02-19 |
2023-08-11 |
human |
| C T Dourish, P H Hutso. Bilateral lesions of the striatum induced with 6-hydroxydopamine abolish apomorphine-induced yawning in rats. Neuropharmacology. vol 24. issue 11. 1986-02-19. PMID:3935946. |
furthermore, it appears that dopaminergic innervation of the striatum may play an important role in the production of yawning elicited by small doses of dopamine agonists. |
1986-02-19 |
2023-08-11 |
rat |
| P R Sanberg, J Pevsner, P G Autuono, J T Coyl. Fetal methylazoxymethanol acetate-induced lesions cause reductions in dopamine receptor-mediated catalepsy and stereotypy. Neuropharmacology. vol 24. issue 11. 1986-02-19. PMID:4080104. |
telencephalic hypoplasia induced by methylazoxymethanol acetate (mam) resulted in increased activity of tyrosine hydroxylase in the striatum, indicative of a relative increase in the density of dopaminergic terminals in the remaining tissue. |
1986-02-19 |
2023-08-11 |
rat |
| I Mocchetti, A Guidotti, J P Schwartz, E Cost. Reserpine changes the dynamic state of enkephalin stores in rat striatum and adrenal medulla by different mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 12. 1986-02-07. PMID:4078631. |
the results in striatum suggest that reserpine increases enkephalin synthesis by removing a tonic dopaminergic inhibition: those in adrenal medulla indicate that reserpine causes an accumulation of enkephalins by blocking the release and/or increasing the processing which may trigger a feedback-regulatory mechanism leading to a decrease in proenkephalin mrna content. |
1986-02-07 |
2023-08-11 |
human |
| G M Tyce, D K Rori. Effects of L-dopa and L-tyrosine on release of free and conjugated dopamine, homovanillic acid and dihydroxyphenylacetic acid from slices of rat striatum. Life sciences. vol 37. issue 25. 1986-02-05. PMID:4079658. |
the data also suggest that conjugation of da occurs chiefly outside of the dopaminergic neurons in striatum. |
1986-02-05 |
2023-08-11 |
rat |
| F Hefti, J Hartikka, M Schlump. Implantation of PC12 cells into the corpus striatum of rats with lesions of the dopaminergic nigrostriatal neurons. Brain research. vol 348. issue 2. 1986-01-28. PMID:4075086. |
implantation of pc12 cells into the corpus striatum of rats with lesions of the dopaminergic nigrostriatal neurons. |
1986-01-28 |
2023-08-11 |
rat |
| F Hefti, J Hartikka, M Schlump. Implantation of PC12 cells into the corpus striatum of rats with lesions of the dopaminergic nigrostriatal neurons. Brain research. vol 348. issue 2. 1986-01-28. PMID:4075086. |
pc12 cells, which have the capacity to synthesize and release catecholamines, were implanted into the corpus striatum of adult rats with lesions of the dopaminergic nigrostriatal pathway. |
1986-01-28 |
2023-08-11 |
rat |
| A Sarrieau, F Javoy-Agid, P Kitabgi, M Dussaillant, M Vial, J P Vincent, Y Agid, W H Rostèn. Characterization and autoradiographic distribution of neurotensin binding sites in the human brain. Brain research. vol 348. issue 2. 1986-01-28. PMID:4075096. |
high density of 125i-nt binding sites were mainly found in dopaminergic (da)-rich areas such as the substantia nigra, the ventral tegmental area, the striatum and the nucleus accumbens, further supporting an interaction between nt and da neurons in human brain. |
1986-01-28 |
2023-08-11 |
human |
| W Dimpfe. Drug-induced field potential changes in dopaminergic target areas after electrical stimulation of the rat mesencephalon. Neuropsychobiology. vol 14. issue 1. 1986-01-22. PMID:2999640. |
the modulation of the responses in prefrontal cortex and striatum induced by intravenous injection of various compounds influencing central dopaminergic transmission is followed. |
1986-01-22 |
2023-08-11 |
rat |
| L Berger, S Gauthier, R Leblan. Akinetic mutism and parkinsonism associated with obstructive hydrocephalus. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 12. issue 3. 1985-11-25. PMID:3876872. |
the parkinson's syndrome and the episodes of akinetic mutism may be related to a reduction of dopaminergic input to the striatum and to the cingulate and frontal cortex brought about or worsened by ventricular dilatation. |
1985-11-25 |
2023-08-11 |
Not clear |
| E Kempf, G Fuhrmann, G Thiriet, A Ebe. Dopamine and serotonin metabolism in striatum and in the septohippocampal pathway of the Snell dwarf mouse. Neurochemical research. vol 10. issue 7. 1985-11-21. PMID:2413382. |
in striatum a sharp decrease in 3-mt levels with a concomitant decrease in da turnover is indicative of a strong decrement in the functional activity of striatal dopaminergic terminals in the mutant mouse. |
1985-11-21 |
2023-08-11 |
mouse |
| R G MacKenzie, M J Zigmon. Chronic neuroleptic treatment increases D-2 but not D-1 receptors in rat striatum. European journal of pharmacology. vol 113. issue 2. 1985-11-14. PMID:2864265. |
it was found that under the appropriate assay conditions [3h]fpt bound to a single saturable site which was most abundant in striatum and bound dopaminergic agonists in the potency order that these drugs demonstrate for adenylate cyclase. |
1985-11-14 |
2023-08-11 |
rat |
| B Hulihan-Giblin, R L Hauger, A Janowsky, S M Pau. Dopaminergic denervation increases [3H](+)-amphetamine binding in the rat striatum. European journal of pharmacology. vol 113. issue 1. 1985-11-12. PMID:3930264. |
dopaminergic denervation increases [3h](+)-amphetamine binding in the rat striatum. |
1985-11-12 |
2023-08-11 |
rat |
| P J Bédard, R Boucher, M Daigle, T Di Paol. Physiological doses of estradiol can increase lingual dyskinesia and cerebrospinal fluid homovanillic acid in monkeys. Neuroscience letters. vol 58. issue 3. 1985-11-06. PMID:2995879. |
the above findings suggest that very small doses of estradiol in the physiological range can increase dopaminergic transmission in the striatum via increased release. |
1985-11-06 |
2023-08-11 |
monkey |
| D R Liskowsky, L T Potte. Muscarine-binding sites localized to cortical dopamine terminals. Neuroscience letters. vol 58. issue 2. 1985-11-05. PMID:2931625. |
this demonstrates that in the frontal cortex, as in the striatum and nucleus accumbens, the activity of dopaminergic terminals may be partially modulated by cholinergic inputs. |
1985-11-05 |
2023-08-11 |
rat |
| J M Durand-Gorde, J Bert, A Nieoullo. Changes in tyrosine hydroxylase, glutamic acid decarboxylase and choline acetyltransferase after local microinoculation of scrapie agent into the nigrostriatal system of the golden hamster. Brain research. vol 341. issue 2. 1985-11-04. PMID:2864098. |
the microinoculation of a homogenate of an infected brain unilaterally into the substantia nigra (sn) provokes a decrease in tyrosine hydroxylase (th), the synthesizing enzyme for dopamine in the dopaminergic neurones, in the striatum ipsilateral to the injected sn. |
1985-11-04 |
2023-08-11 |
Not clear |
| M Morelli, G Di Chiar. Non-dopaminergic mechanisms in the turning behavior evoked by intranigral opiates. Brain research. vol 341. issue 2. 1985-11-04. PMID:2864100. |
in order to study the role of the dopaminergic nigrostriatal system, we made unilateral lesions of the medial forebrain bundle (mfb) with 6-hydroxydopamine (6-ohda) and kainic acid lesions of the striatum and we looked at the effect elicited by these lesions on the behavior produced by the above compounds when injected into the sn. |
1985-11-04 |
2023-08-11 |
rat |
| G Arbuthnott, S Dunnett, N MacLeo. Electrophysiological properties of single units in dopamine-rich mesencephalic transplants in rat brain. Neuroscience letters. vol 57. issue 2. 1985-10-07. PMID:2993967. |
whereas all rats had surviving grafts, half of the rats showed recovery from amphetamine-induced rotational asymmetry induced by the 6-ohda lesions ('compensation'), indicating a functional dopaminergic reinnervation of the host striatum by the graft. |
1985-10-07 |
2023-08-11 |
rat |
| M Docherty, H F Bradford, J Y Wu, T H Joh, D J Rei. Evidence for specific immunolysis of nerve terminals using antisera against choline acetyltransferase, glutamate decarboxylase and tyrosine hydroxylase. Brain research. vol 339. issue 1. 1985-10-01. PMID:2862953. |
antibodies against tyrosine hydroxylase lysed only the dopaminergic terminals in striatum but not noradrenergic terminals in cortex. |
1985-10-01 |
2023-08-11 |
rat |