| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A A Hancock, C L Mars. Distinctions between ligand-binding sites for [3H]dopamine and D2 dopaminergic receptors characterized with [3H]spiroperidol. Molecular pharmacology. vol 26. issue 3. 1984-12-20. PMID:6238230. |
the binding of [3h]hspiroperidol to d2 dopaminergic receptors in rat striatum was compared to the binding of [3h]dopamine to its binding sites. |
1984-12-20 |
2023-08-12 |
rat |
| J Kornhuber, J S Kim, M E Kornhuber, H H Kornhube. Chronic haloperidol administration enhances the gamma-aminobutyric acid level in the rat striatum without altering the glutamate level. European neurology. vol 23. issue 4. 1984-12-20. PMID:6541578. |
the unaltered gaba level in the substantia nigra is compatible with the existence of gabaergic interneurons in the striatum, which are inhibited by the afferent dopaminergic innervation to the striatum. |
1984-12-20 |
2023-08-12 |
rat |
| P Moleman, C F van Valkenburg, J A vd Krog. Effects of morphine on dopamine metabolism in rat striatum and limbic structures in relation to the activity of dopaminergic neurones. Naunyn-Schmiedeberg's archives of pharmacology. vol 327. issue 3. 1984-12-19. PMID:6493361. |
effects of morphine on dopamine metabolism in rat striatum and limbic structures in relation to the activity of dopaminergic neurones. |
1984-12-19 |
2023-08-12 |
rat |
| V Leviel, C Kerny, C Barberis, B Guibert, F Daude. Blockade by frontocortical lesion of reciprocal regulation between the two nigrostriatal dopaminergic pathways. Neuroscience. vol 13. issue 1. 1984-12-18. PMID:6092996. |
these results suggest that the cortical structures are involved not only in the transfer of information between the two dopaminergic pathways but are also involved with regulation of the release of dopamine in the striatum originating in the substantia nigra. |
1984-12-18 |
2023-08-12 |
Not clear |
| T Fukuda, T Tsumagar. [Effects of psychotropic drugs on lateral hypothalamic self-stimulation behavior in rats: correlation between self-stimulation behavior inhibition and striatal dopaminergic blockade by neuroleptic drugs]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 83. issue 6. 1984-12-18. PMID:6149172. |
no correlation was found between the ed50 values for the turning behavior inhibition and the ed50 values for the self-stimulation behavior inhibition produced by these drugs, so the dopaminergic receptors in the striatum are apparently not involved in the mediation of self-stimulation behavior. |
1984-12-18 |
2023-08-12 |
rat |
| M E Trulso. Effects of diazepam on behavior and dopamine-containing substantia nigra units in freely moving cats. Psychopharmacology. vol 84. issue 1. 1984-12-18. PMID:6436896. |
these data suggest that diazepam and other centrally acting muscle relaxants may produce their effects on motoric behavior in part by altering the dopaminergic input to the striatum. |
1984-12-18 |
2023-08-12 |
Not clear |
| R A Bjur, D P Westfal. The effects of dopaminergic denervation on Na+-K+ ATPase activity and 3H-ouabain binding in rat corpus striatum. Proceedings of the Western Pharmacology Society. vol 27. 1984-12-14. PMID:6093132. |
the effects of dopaminergic denervation on na+-k+ atpase activity and 3h-ouabain binding in rat corpus striatum. |
1984-12-14 |
2023-08-12 |
rat |
| S Arbilla, S Z Lange. Differential effects of the stereoisomers of 3PPP on dopaminergic and cholinergic neurotransmission in superfused slices of the corpus striatum. Naunyn-Schmiedeberg's archives of pharmacology. vol 327. issue 1. 1984-12-05. PMID:6092969. |
differential effects of the stereoisomers of 3ppp on dopaminergic and cholinergic neurotransmission in superfused slices of the corpus striatum. |
1984-12-05 |
2023-08-12 |
rat |
| R G MacKenzie, M J Zigmon. High- and low-affinity states of striatal D2 receptors are not affected by 6-hydroxydopamine or chronic haloperidol treatment. Journal of neurochemistry. vol 43. issue 5. 1984-11-26. PMID:6208330. |
specific d2 binding in rat striatum was characterized and then the effects of chronic disruption of dopaminergic activity on antagonist and agonist binding to these sites were studied. |
1984-11-26 |
2023-08-12 |
rat |
| E T Rolls, S J Thorpe, M Boytim, I Szabo, D I Perret. Responses of striatal neurons in the behaving monkey. 3. Effects of iontophoretically applied dopamine on normal responsiveness. Neuroscience. vol 12. issue 4. 1984-11-09. PMID:6148716. |
it is suggested that this type of effect of dopamine could influence the signal to noise ratio of processing within the striatum, and that changes in this signal to noise ratio produced by disturbances of dopaminergic function could contribute to the behavioral disorders produced by dysfunctions of the dopaminergic systems. |
1984-11-09 |
2023-08-12 |
monkey |
| J F Van der Werf, J B Sebens, J Kor. In vivo binding of N-n-propylnorapomorphine in the rat striatum: quantification after lesions produced by kainate, 6-hydroxydopamine and decortication. European journal of pharmacology. vol 102. issue 2. 1984-11-09. PMID:6434329. |
with a tracer dose of [3h]npa less radioactivity accumulated in the ka-lesioned striatum, while after unilateral destruction of the dopaminergic pathway more radioactivity was found in the ipsilateral striatum and no bilateral differences in striatal radioactivity concentration were found after unilateral cortical ablation. |
1984-11-09 |
2023-08-12 |
rat |
| M F Beal, J B Marti. Effects of neuroleptic drugs on brain somatostatin-like-immunoreactivity. Neuroscience letters. vol 47. issue 2. 1984-09-14. PMID:6146954. |
the present findings provide further evidence of an interaction between somatostatin and dopaminergic neurons in the striatum. |
1984-09-14 |
2023-08-12 |
Not clear |
| M T Lin, J J Wu, Y F Cher. Administration of prostaglandin E2 into the striatum induces hyperthermia in rats. Experimental neurology. vol 85. issue 2. 1984-08-30. PMID:6589168. |
furthermore, the pge2-induced hyperthermia was antagonized by prior intrastriatal injection of kainic acid (to destroy cell bodies in the striatum) but not by pretreatment with 6-hydroxydopamine (to destroy the dopaminergic nerve fibers in the striatum). |
1984-08-30 |
2023-08-12 |
rat |
| S E Spencer, G F Woote. Altered pharmacokinetics of L-dopa metabolism in rat striatum deprived of dopaminergic innervation. Neurology. vol 34. issue 8. 1984-08-29. PMID:6540390. |
altered pharmacokinetics of l-dopa metabolism in rat striatum deprived of dopaminergic innervation. |
1984-08-29 |
2023-08-12 |
rat |
| J A Javitch, R O Blaustein, S H Snyde. [3H]mazindol binding associated with neuronal dopamine and norepinephrine uptake sites. Molecular pharmacology. vol 26. issue 1. 1984-08-27. PMID:6087116. |
the association of [3h]mazindol binding sites with neuronal dopamine uptake sites in the corpus striatum is further supported by the reduction of [3h]mazindol binding sites in striatal membranes following destruction of dopaminergic neurons by 6-hydroxydopamine. |
1984-08-27 |
2023-08-12 |
Not clear |
| M J Zigmond, A L Acheson, M K Stachowiak, E M Stricke. Neurochemical compensation after nigrostriatal bundle injury in an animal model of preclinical parkinsonism. Archives of neurology. vol 41. issue 8. 1984-08-27. PMID:6147127. |
in our studies, damage to the nigrostriatal bundle of the rat, resulting in the loss of up to 95% of the dopaminergic terminals in striatum, was accompanied by apparent increases in the synthesis and release of dopamine (da) from those dopaminergic terminals that remained. |
1984-08-27 |
2023-08-12 |
rat |
| G Toffano, G Savoini, C Aldinio, G Valenti, R Dal Toso, A Leon, L Calza, I Zini, L F Agnati, K Fux. Effects of gangliosides on the functional recovery of damaged brain. Advances in experimental medicine and biology. vol 174. 1984-08-23. PMID:6741741. |
gm1 treatment favoured the collateral sprouting of dopaminergic axons in the striatum as indicated by the induced increase of tyrosine hydroxylase (th) activity and immunofluorescence. |
1984-08-23 |
2023-08-12 |
rat |
| M J Zigmond, E M Stricke. Parkinson's disease: studies with an animal model. Life sciences. vol 35. issue 1. 1984-08-14. PMID:6146085. |
it appears that a variety of stressors produce an abrupt but transient increase in dopaminergic activity in the striatum of intact animals and that this increase is markedly attenuated by 6-hydroxydopamine treatment. |
1984-08-14 |
2023-08-12 |
rat |
| M R Rosenfeld, B Dvorkin, P N Klein, M H Makma. Differential affinities of molindone, metoclopramide and domperidone for classes of [3H]spiroperidol binding sites in rat striatum: evidence for pharmacologically distinct classes of receptors. Brain research. vol 235. issue 1. 1984-08-13. PMID:6145486. |
rat striatum contains two populations of dopaminergic [3h]spiroperidol binding sites. |
1984-08-13 |
2023-08-12 |
rat |
| P J Roberts, G J McBean, N A Sharif, E M Thoma. Striatal glutamatergic function: modifications following specific lesions. Brain research. vol 235. issue 1. 1984-08-13. PMID:6145487. |
ibotenate lesions which destroy target neurones for the glutamatergic fibres (sparing terminals), reduced glutamate binding in the striatum, as did nigral 6-ohda lesions which delete striatal dopaminergic terminals. |
1984-08-13 |
2023-08-12 |
Not clear |