| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D L DeHaven, M R Krigman, R B Mailma. Temporal changes in dopaminergic and serotonergic function caused by administration of trimethyltin to adult rats. Neurobehavioral toxicology and teratology. vol 8. issue 5. 1987-01-21. PMID:2431332. |
in concert with our previous studies, these data indicate that administration of tmt continues to affect serotonergic systems up to 28 days, and dopaminergic systems up to 21 days after exposure, with striatum, nucleus accumbens, olfactory tubercle and septum exhibiting persistent effects due to administration of this neurotoxicant. |
1987-01-21 |
2023-08-11 |
rat |
| I Kanazawa, Y Tanaka, F Ch. 'Choreic' movement induced by unilateral kainate lesion of the striatum and L-DOPA administration in monkey. Neuroscience letters. vol 71. issue 2. 1987-01-16. PMID:3024077. |
therefore, choreic movements in a monkey were suggested to be generated by the hyperfunction of the nigrostriatal dopaminergic neurons that innervate the unaffected part of the striatum. |
1987-01-16 |
2023-08-11 |
monkey |
| J G Cannon, V E Amoo, J P Long, R K Bhatnagar, J R Flyn. p-Dimethoxy-substituted trans-octahydrobenzo[f]- and -[g]quinolines: synthesis and assessment of dopaminergic agonist effects. Journal of medicinal chemistry. vol 29. issue 12. 1987-01-16. PMID:3783613. |
both the angularly and the linearly annulated trans-benzoquinoline ring derivatives displayed prominent da2 dopaminergic effects on the peripheral sympathetic nerve terminal and displayed postjunctional dopamine receptor agonist properties in the striatum. |
1987-01-16 |
2023-08-11 |
Not clear |
| C F Saller, A I Salam. 3-Methoxytyramine accumulation: effects of typical neuroleptics and various atypical compounds. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 2. 1987-01-15. PMID:2878374. |
the accumulation of 3-methoxytyramine (3-mt), the o-methylated metabolite of dopamine (da), in rat striatum was used to assess the effects of drugs on dopaminergic activity. |
1987-01-15 |
2023-08-11 |
rat |
| J Knol. [Medicamentous strategy for improving the quality of life in the senescence]. Wiener medizinische Wochenschrift. Supplement. vol 98. 1987-01-05. PMID:3097965. |
the striatum, in which the nigrostriatal dopaminergic neurons terminate, contains the highest amount of dopamine da) in the brain. |
1987-01-05 |
2023-08-11 |
human |
| C Rauca, H Matthie. The effect of beta-casomorphins on the apomorphine- and amphetamine-induced turning after nigral lesions in rats. Neuropharmacology. vol 25. issue 10. 1987-01-02. PMID:3785581. |
the beta-casomorphins studied, (d-pro4-beta-casomorphin1-5, d-phe3-beta-casomorphin1-5, des-tyr1-d-pro4-beta-casomorphin2-5 or des-tyr1-d-phe3-beta-casomorphin2-5), did not change postsynaptic dopaminergic processes in the striatum of the rat after intraperitoneal injection of apomorphine. |
1987-01-02 |
2023-08-11 |
rat |
| C Rauca, H Matthie. The effect of beta-casomorphins on the apomorphine- and amphetamine-induced turning after nigral lesions in rats. Neuropharmacology. vol 25. issue 10. 1987-01-02. PMID:3785581. |
increased amphetamine-evoked turning could be observed after intrastriatal application of tyrosine-containing beta-casomorphins (d-pro4-beta-casomorphin1-5 or d-phe3-beta-casomorphin1-5), whereas presynaptic dopaminergic mechanisms were inhibited by injection of the corresponding des-tyrosine beta-casomorphin analogs (des-tyr1-d-pro4-beta-casomorphin2-5 or des-tyr1-d-phe3-beta-casomorphin2-5) into the striatum after administration of amphetamine. |
1987-01-02 |
2023-08-11 |
rat |
| M Traub, A Reches, H R Wagner, S Fah. Reserpine-induced up-regulation of dopamine D2 receptors in the rat striatum is enhanced by denervation but not by chronic receptor blockade. Neuroscience letters. vol 70. issue 2. 1986-12-18. PMID:2946007. |
compensatory increases in the density of dopamine (da) d2 receptors in the rat striatum occur following chronic interruption of dopaminergic neurotransmission. |
1986-12-18 |
2023-08-11 |
rat |
| G el Gemayel, J H Trouvin, M Prioux-Guyonneau, C Jacquot, Y Cohe. Dopaminergic metabolism in various rat brain areas after L-dopa loading. The Journal of pharmacy and pharmacology. vol 38. issue 9. 1986-12-17. PMID:2877071. |
after l-dopa loading, da, dopac and hva were increased in all the structures, but the largest increases were in those tissues with the less dopaminergic activity, while 3-mt increased in the hypothalamus, hippocampus and cerebellum but was lowered in striatum. |
1986-12-17 |
2023-08-11 |
rat |
| G el Gemayel, J H Trouvin, M Prioux-Guyonneau, C Jacquot, Y Cohe. Dopaminergic metabolism in various rat brain areas after L-dopa loading. The Journal of pharmacy and pharmacology. vol 38. issue 9. 1986-12-17. PMID:2877071. |
the data provide evidence that the striatum, by feed-back mechanisms and specific enzymatic activity, is able to ensure a better regulation of dopaminergic activity than the other structures, thereby overcoming excess l-dopa. |
1986-12-17 |
2023-08-11 |
rat |
| M Herrera-Marschitz, I Christensson-Nylander, T Sharp, W Staines, M Reid, T Hökfelt, L Terenius, U Ungersted. Striato-nigral dynorphin and substance P pathways in the rat. II. Functional analysis. Experimental brain research. vol 64. issue 1. 1986-12-16. PMID:2429859. |
attempts were made to evaluate whether these striato-nigral neurons have a feed-back modulatory action on the dopaminergic nigro-striatal system, or whether they represent an outflow pathway conveying motor information from the striatum. |
1986-12-16 |
2023-08-11 |
rat |
| I Strömberg, H Björklund, D Dahl, G Jonsson, E Sundström, L Olso. Astrocyte responses to dopaminergic denervations by 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as evidenced by glial fibrillary acidic protein immunohistochemistry. Brain research bulletin. vol 17. issue 2. 1986-11-24. PMID:3094835. |
mptp given systemically to mice in a dose that causes marked dopaminergic denervation of striatum also caused marked increases of gfa-immunoreactivity in striatum. |
1986-11-24 |
2023-08-11 |
mouse |
| N Ono, R Saito, T Abiru, H Kamiya, T Furukaw. Possible involvement of prostaglandins in cataleptic behavior in rats. Pharmacology, biochemistry, and behavior. vol 25. issue 2. 1986-11-21. PMID:3020596. |
the pg f2a- and haloperidol-induced cataleptic behaviors were almost abolished by the thermal coagulation of bilateral striatum where the dopaminergic and cholinergic link is found. |
1986-11-21 |
2023-08-11 |
rat |
| S P Butcher, P J Roberts, J F Collin. The distribution and function of DL-[3H]2-amino-4-phosphonobutyrate binding sites in the rat striatum. Brain research. vol 381. issue 2. 1986-11-20. PMID:3092992. |
this finding supports the proposed existence of functional acidic amino acid receptors on dopaminergic terminals in the striatum. |
1986-11-20 |
2023-08-11 |
rat |
| S Govoni, L Lucchi, C Missale, M Memo, P F Spano, M Trabucch. Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens. Brain research. vol 381. issue 1. 1986-11-20. PMID:3756492. |
effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens. |
1986-11-20 |
2023-08-11 |
rat |
| S Mazzari, C Aldinio, M Beccaro, G Toffano, R Schwarc. Intracerebral quinolinic acid injection in the rat: effects on dopaminergic neurons. Brain research. vol 380. issue 2. 1986-11-18. PMID:2944562. |
at the later timepoints examined (6 h, 4 and 11 days after quin), dopaminergic parameters are increased in the injected striatum only while no changes can be detected in the homolateral substantia nigra. |
1986-11-18 |
2023-08-11 |
rat |
| S Mazzari, C Aldinio, M Beccaro, G Toffano, R Schwarc. Intracerebral quinolinic acid injection in the rat: effects on dopaminergic neurons. Brain research. vol 380. issue 2. 1986-11-18. PMID:2944562. |
the acute increase in nigrostriatal activity may be mediated by an excessively stimulated, yet functional striatonigral feedback loop whereas subsequent changes represent local reactions of dopaminergic nerve terminals secondary to neuronal degeneration in the striatum. |
1986-11-18 |
2023-08-11 |
rat |
| H Sershen, M F Mason, E A Debler, A Lajth. Kinetics of [3H]MPP+ uptake in dopaminergic neurons of mouse: regional effects of MPTP neurotoxicity. European journal of pharmacology. vol 126. issue 3. 1986-11-12. PMID:3489627. |
in an effort to determine the specificity of mptp/mpp+ toxicity with respect to the dopaminergic systems, the effect of prior mptp treatment on [3h]mpp+ uptake in the striatum and olfactory tubercle of balb/cby mice was examined. |
1986-11-12 |
2023-08-11 |
mouse |
| H Sershen, M F Mason, E A Debler, A Lajth. Kinetics of [3H]MPP+ uptake in dopaminergic neurons of mouse: regional effects of MPTP neurotoxicity. European journal of pharmacology. vol 126. issue 3. 1986-11-12. PMID:3489627. |
mptp treatment did not significantly alter the km in either region, although mpp+ accumulates in both olfactory tubercle and striatum, these dopaminergic systems show different sensitivity to the neurotoxicity of mptp/mpp+. |
1986-11-12 |
2023-08-11 |
mouse |
| E Kosar, A Sumová, B Jakoube. Ergot alkaloids inhibit 3H-naloxone binding to opiate receptors in the rat striatum and hippocampus. Physiologia Bohemoslovaca. vol 35. issue 4. 1986-11-10. PMID:3020603. |
in the striatum they found that dh-ergotoxine (a substance with high affinity for noradrenergic receptors) inhibited specific 3h-naloxone binding much more strongly than lisuride and terguride (substances with a greater affinity for dopaminergic and serotoninergic receptors). |
1986-11-10 |
2023-08-11 |
rat |