| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G el Gemayel, J H Trouvin, M Prioux-Guyonneau, C Jacquot, Y Cohe. Dopaminergic metabolism in various rat brain areas after L-dopa loading. The Journal of pharmacy and pharmacology. vol 38. issue 9. 1986-12-17. PMID:2877071. |
the data provide evidence that the striatum, by feed-back mechanisms and specific enzymatic activity, is able to ensure a better regulation of dopaminergic activity than the other structures, thereby overcoming excess l-dopa. |
1986-12-17 |
2023-08-11 |
rat |
| M Herrera-Marschitz, I Christensson-Nylander, T Sharp, W Staines, M Reid, T Hökfelt, L Terenius, U Ungersted. Striato-nigral dynorphin and substance P pathways in the rat. II. Functional analysis. Experimental brain research. vol 64. issue 1. 1986-12-16. PMID:2429859. |
attempts were made to evaluate whether these striato-nigral neurons have a feed-back modulatory action on the dopaminergic nigro-striatal system, or whether they represent an outflow pathway conveying motor information from the striatum. |
1986-12-16 |
2023-08-11 |
rat |
| I Strömberg, H Björklund, D Dahl, G Jonsson, E Sundström, L Olso. Astrocyte responses to dopaminergic denervations by 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine as evidenced by glial fibrillary acidic protein immunohistochemistry. Brain research bulletin. vol 17. issue 2. 1986-11-24. PMID:3094835. |
mptp given systemically to mice in a dose that causes marked dopaminergic denervation of striatum also caused marked increases of gfa-immunoreactivity in striatum. |
1986-11-24 |
2023-08-11 |
mouse |
| N Ono, R Saito, T Abiru, H Kamiya, T Furukaw. Possible involvement of prostaglandins in cataleptic behavior in rats. Pharmacology, biochemistry, and behavior. vol 25. issue 2. 1986-11-21. PMID:3020596. |
the pg f2a- and haloperidol-induced cataleptic behaviors were almost abolished by the thermal coagulation of bilateral striatum where the dopaminergic and cholinergic link is found. |
1986-11-21 |
2023-08-11 |
rat |
| S P Butcher, P J Roberts, J F Collin. The distribution and function of DL-[3H]2-amino-4-phosphonobutyrate binding sites in the rat striatum. Brain research. vol 381. issue 2. 1986-11-20. PMID:3092992. |
this finding supports the proposed existence of functional acidic amino acid receptors on dopaminergic terminals in the striatum. |
1986-11-20 |
2023-08-11 |
rat |
| S Govoni, L Lucchi, C Missale, M Memo, P F Spano, M Trabucch. Effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens. Brain research. vol 381. issue 1. 1986-11-20. PMID:3756492. |
effect of lead exposure on dopaminergic receptors in rat striatum and nucleus accumbens. |
1986-11-20 |
2023-08-11 |
rat |
| S Mazzari, C Aldinio, M Beccaro, G Toffano, R Schwarc. Intracerebral quinolinic acid injection in the rat: effects on dopaminergic neurons. Brain research. vol 380. issue 2. 1986-11-18. PMID:2944562. |
at the later timepoints examined (6 h, 4 and 11 days after quin), dopaminergic parameters are increased in the injected striatum only while no changes can be detected in the homolateral substantia nigra. |
1986-11-18 |
2023-08-11 |
rat |
| S Mazzari, C Aldinio, M Beccaro, G Toffano, R Schwarc. Intracerebral quinolinic acid injection in the rat: effects on dopaminergic neurons. Brain research. vol 380. issue 2. 1986-11-18. PMID:2944562. |
the acute increase in nigrostriatal activity may be mediated by an excessively stimulated, yet functional striatonigral feedback loop whereas subsequent changes represent local reactions of dopaminergic nerve terminals secondary to neuronal degeneration in the striatum. |
1986-11-18 |
2023-08-11 |
rat |
| H Sershen, M F Mason, E A Debler, A Lajth. Kinetics of [3H]MPP+ uptake in dopaminergic neurons of mouse: regional effects of MPTP neurotoxicity. European journal of pharmacology. vol 126. issue 3. 1986-11-12. PMID:3489627. |
in an effort to determine the specificity of mptp/mpp+ toxicity with respect to the dopaminergic systems, the effect of prior mptp treatment on [3h]mpp+ uptake in the striatum and olfactory tubercle of balb/cby mice was examined. |
1986-11-12 |
2023-08-11 |
mouse |
| H Sershen, M F Mason, E A Debler, A Lajth. Kinetics of [3H]MPP+ uptake in dopaminergic neurons of mouse: regional effects of MPTP neurotoxicity. European journal of pharmacology. vol 126. issue 3. 1986-11-12. PMID:3489627. |
mptp treatment did not significantly alter the km in either region, although mpp+ accumulates in both olfactory tubercle and striatum, these dopaminergic systems show different sensitivity to the neurotoxicity of mptp/mpp+. |
1986-11-12 |
2023-08-11 |
mouse |
| E Kosar, A Sumová, B Jakoube. Ergot alkaloids inhibit 3H-naloxone binding to opiate receptors in the rat striatum and hippocampus. Physiologia Bohemoslovaca. vol 35. issue 4. 1986-11-10. PMID:3020603. |
in the striatum they found that dh-ergotoxine (a substance with high affinity for noradrenergic receptors) inhibited specific 3h-naloxone binding much more strongly than lisuride and terguride (substances with a greater affinity for dopaminergic and serotoninergic receptors). |
1986-11-10 |
2023-08-11 |
rat |
| W G Erwin, T F Turc. Current concepts in clinical therapeutics: Parkinson's disease. Clinical pharmacy. vol 5. issue 9. 1986-11-03. PMID:3530616. |
the clinical features of parkinsonism result from a depletion in dopaminergic transmission in the corpus striatum; the dopamine deficiency is caused by a loss of melanin-containing nerve cells within the substantia nigra and locus ceruleus. |
1986-11-03 |
2023-08-11 |
Not clear |
| G Zsilla, P Földi, G Held, A M Székely, J Knol. The effect of repeated doses of (-) deprenyl on the dynamics of monoaminergic transmission. Comparison with clorgyline. Polish journal of pharmacology and pharmacy. vol 38. issue 1. 1986-10-30. PMID:3020531. |
beside the augmentation of the dopamine turnover rate, the dopaminergic tone was also elevated by the reduction of the dopamine uptake in the striatum. |
1986-10-30 |
2023-08-11 |
rat |
| Y Ihara, M Sato, S Otsuki, H Kaiya, M Namb. Morphological changes in rat striatal boutons after chronic methamphetamine and haloperidol treatment. Neuroscience research. vol 3. issue 5. 1986-10-22. PMID:3748472. |
dopaminergic (da) synaptic boutons were identified in rat striatum with an electron microscopic histochemical method. |
1986-10-22 |
2023-08-11 |
rat |
| T Nabeshima, M Hiramatsu, H Furukawa, T Kameyam. Effects of phencyclidine in combination with morphine on the levels of met-enkephalin, dopamine, DOPAC and HVA in discrete brain areas of mice. Neuropharmacology. vol 24. issue 8. 1986-10-21. PMID:3837860. |
these results suggest that pcp may change the function in dopaminergic and enkephalinergic neuronal systems in the midbrain and/or striatum. |
1986-10-21 |
2023-08-11 |
mouse |
| G J Treisman, N Muirhead, M E Gneg. Increased sensitivity of adenylate cyclase activity in the striatum of the rat to calmodulin and GppNHp after chronic treatment with haloperidol. Neuropharmacology. vol 25. issue 6. 1986-10-16. PMID:3092124. |
chronic treatment of rats with haloperidol causes behavioral supersensitivity to dopaminergic agonists and an increase in the sensitivity of adenylate cyclase activity in the striatum to stimulation by dopamine. |
1986-10-16 |
2023-08-11 |
rat |
| I J Wajda, M Banay-Schwartz, I Manigault, A Lajth. Modulation of the serotonin S2-receptor in brain after chronic lithium. Neurochemical research. vol 11. issue 7. 1986-10-09. PMID:2944024. |
in vivo effects of chronic lithium administration on dopaminergic and serotonergic receptor binding were studied in the striatum and cerebral cortex of the rat. |
1986-10-09 |
2023-08-11 |
rat |
| J M Roberts-Lewis, P H Roseboom, L M Iwaniec, M E Gneg. Differential down-regulation of D1-stimulated adenylate cyclase activity in rat forebrain after in vivo amphetamine treatments. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 8. 1986-10-02. PMID:3018190. |
these findings demonstrate that amphetamine treatments result in a down-regulation of striatal, but not mesolimbic, dopamine-sensitive adenylate cyclase activity that parallels the intense, stereotyped behaviors characteristic of dopaminergic activation in the striatum. |
1986-10-02 |
2023-08-11 |
rat |
| D Herve, J P Tassin, J M Studler, C Dana, P Kitabgi, J P Vincent, J Glowinski, W Rosten. Dopaminergic control of 125I-labeled neurotensin binding site density in corticolimbic structures of the rat brain. Proceedings of the National Academy of Sciences of the United States of America. vol 83. issue 16. 1986-09-25. PMID:3016745. |
in the rat brain, destruction of dopaminergic cell groups by injections of 6-hydroxydopamine into the ventral mesencephalic tegmentum results in large decreases in the number of neurotensin binding sites in the mesencephalon and the striatum. |
1986-09-25 |
2023-08-11 |
rat |
| J Kornhuber, M E Kornhube. Presynaptic dopaminergic modulation of cortical input to the striatum. Life sciences. vol 39. issue 8. 1986-09-18. PMID:2874471. |
presynaptic dopaminergic modulation of cortical input to the striatum. |
1986-09-18 |
2023-08-11 |
Not clear |