| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Tomozawa, S H Appe. Soluble striatal extracts enhance development of mesencephalic dopaminergic neurons in vitro. Brain research. vol 399. issue 1. 1987-03-19. PMID:3801914. |
in this report, we use catecholamine cytofluorescence to demonstrate that a soluble factor from the striatum produces a 4-fold increase in number of catecholamine cytofluorescent-positive dopaminergic neurons in dissociated mesencephalon cultures prepared from embryonic 14-day-old rats. |
1987-03-19 |
2023-08-11 |
rat |
| Y Tomozawa, S H Appe. Soluble striatal extracts enhance development of mesencephalic dopaminergic neurons in vitro. Brain research. vol 399. issue 1. 1987-03-19. PMID:3801914. |
the trophic effects on dopaminergic neurons are maximal in extracts of the striatum, but are also found in extracts of the hippocampus-entorhinal cortex-amygdaloid nucleus and the cerebral cortex, although they are less in extracts of the cerebellum, negligible in the olfactory bulb, and absent in the liver. |
1987-03-19 |
2023-08-11 |
rat |
| R de Beaurepaire, W J Free. Embryonic substantia nigra grafts innervate embryonic striatal co-grafts in preference to mature host striatum. Experimental neurology. vol 95. issue 2. 1987-03-17. PMID:3100320. |
this limited reinnervation may be due to the fact that adult denervated striatum is not an ideal target for dopaminergic neurites. |
1987-03-17 |
2023-08-11 |
rat |
| R de Beaurepaire, W J Free. Embryonic substantia nigra grafts innervate embryonic striatal co-grafts in preference to mature host striatum. Experimental neurology. vol 95. issue 2. 1987-03-17. PMID:3100320. |
we conclude that embryonic striatum is a better target tissue than adult denervated striatum for developing dopaminergic neurites and hypothesize that this difference may be due to the presence or the absence of specific trophic factors. |
1987-03-17 |
2023-08-11 |
rat |
| G R Breese, G E Duncan, T C Napier, S C Bondy, L C Iorio, R A Muelle. 6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding. The Journal of pharmacology and experimental therapeutics. vol 240. issue 1. 1987-02-27. PMID:3100767. |
in contrast to this lack of change in binding characteristics in 6-ohda-lesioned rats, blockade of dopaminergic transmission with haloperidol treatment caused an elevation of [3h]spiperone binding sites in striatum without affecting affinity for the site. |
1987-02-27 |
2023-08-11 |
rat |
| M K James, L X Cubedd. Pharmacologic characterization and functional role of muscarinic autoreceptors in the rabbit striatum. The Journal of pharmacology and experimental therapeutics. vol 240. issue 1. 1987-02-27. PMID:3806384. |
these data suggest that muscarinic autoreceptors in the striatum do not regulate physiologic ach release in the presence of intact acetylcholinesterase and that the interaction of dopaminergic and cholinergic neurons in the striatum may not be simple trans-synaptic inhibition. |
1987-02-27 |
2023-08-11 |
rabbit |
| J Korf, J B Seben. Relationship between dopamine receptor occupation by spiperone and acetylcholine levels in the rat striatum after long-term haloperidol treatment depends on dopamine innervation. Journal of neurochemistry. vol 48. issue 2. 1987-02-19. PMID:2878979. |
after lesioning of the dopaminergic pathway, there was no longer a correlation between the receptor occupation and ach levels in the striatum. |
1987-02-19 |
2023-08-11 |
rat |
| A M Graybiel, E C Hirsch, Y A Agi. Differences in tyrosine hydroxylase-like immunoreactivity characterize the mesostriatal innervation of striosomes and extrastriosomal matrix at maturity. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 1. 1987-02-18. PMID:2879289. |
these observations add to evidence that dopaminergic modulation of neural processing in the mature striatum is organized in accordance with striosomal architecture and suggest that part of the mechanism for such differentiation may involve presynaptic differences in enzymatic regulation of dopamine content in and out of striosomes. |
1987-02-18 |
2023-08-11 |
human |
| H Sershen, M F Mason, M E Reith, A Hashim, A Lajth. Effect of nicotine and amphetamine on the neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mice. Neuropharmacology. vol 25. issue 11. 1987-02-11. PMID:3491964. |
the present results show the potentiating effect of amphetamine on the ability of mptp to destroy dopaminergic neurons in striatum of the mouse. |
1987-02-11 |
2023-08-11 |
mouse |
| C Mermet, F Gono. In vivo voltammetric monitoring of noradrenaline release and catecholamine metabolism in the hypothalamic paraventricular nucleus. Neuroscience. vol 19. issue 3. 1987-02-05. PMID:3796818. |
this peak was mainly due to 3,4-dihydroxyphenylacetic acid synthesized by noradrenergic terminals since: it appeared at the same oxidation potential as 3,4-dihydroxyphenylacetic acid in vitro; it was rapidly suppressed after inhibition of tyrosine hydroxylase by alpha-methyl-p-tyrosine or monoamine oxidase by pargyline; blockade of dopamine-beta-hydroxylase by fla 63 induced a marked increase in this signal, whereas this drug was without effect in dopaminergic terminals fields (striatum, zona incerta); stimulation of alpha 2 noradrenergic receptors by clonidine (50 micrograms/kg) decreased the peak height and this effect was reversed by piperoxane (30 mg/kg). |
1987-02-05 |
2023-08-11 |
rat |
| P Themann, U Havemann, K Kuschinsk. On the mechanisms of the development of tolerance to the muscular rigidity produced by morphine in rats. European journal of pharmacology. vol 129. issue 3. 1987-01-22. PMID:3780846. |
the results suggest that rigidity, which is assumed to be due to an action of morphine in the striatum, can be antagonized by another process leading to dopaminergic activation in the striatum. |
1987-01-22 |
2023-08-11 |
rat |
| D L DeHaven, M R Krigman, R B Mailma. Temporal changes in dopaminergic and serotonergic function caused by administration of trimethyltin to adult rats. Neurobehavioral toxicology and teratology. vol 8. issue 5. 1987-01-21. PMID:2431332. |
in concert with our previous studies, these data indicate that administration of tmt continues to affect serotonergic systems up to 28 days, and dopaminergic systems up to 21 days after exposure, with striatum, nucleus accumbens, olfactory tubercle and septum exhibiting persistent effects due to administration of this neurotoxicant. |
1987-01-21 |
2023-08-11 |
rat |
| I Kanazawa, Y Tanaka, F Ch. 'Choreic' movement induced by unilateral kainate lesion of the striatum and L-DOPA administration in monkey. Neuroscience letters. vol 71. issue 2. 1987-01-16. PMID:3024077. |
therefore, choreic movements in a monkey were suggested to be generated by the hyperfunction of the nigrostriatal dopaminergic neurons that innervate the unaffected part of the striatum. |
1987-01-16 |
2023-08-11 |
monkey |
| J G Cannon, V E Amoo, J P Long, R K Bhatnagar, J R Flyn. p-Dimethoxy-substituted trans-octahydrobenzo[f]- and -[g]quinolines: synthesis and assessment of dopaminergic agonist effects. Journal of medicinal chemistry. vol 29. issue 12. 1987-01-16. PMID:3783613. |
both the angularly and the linearly annulated trans-benzoquinoline ring derivatives displayed prominent da2 dopaminergic effects on the peripheral sympathetic nerve terminal and displayed postjunctional dopamine receptor agonist properties in the striatum. |
1987-01-16 |
2023-08-11 |
Not clear |
| C F Saller, A I Salam. 3-Methoxytyramine accumulation: effects of typical neuroleptics and various atypical compounds. Naunyn-Schmiedeberg's archives of pharmacology. vol 334. issue 2. 1987-01-15. PMID:2878374. |
the accumulation of 3-methoxytyramine (3-mt), the o-methylated metabolite of dopamine (da), in rat striatum was used to assess the effects of drugs on dopaminergic activity. |
1987-01-15 |
2023-08-11 |
rat |
| J Knol. [Medicamentous strategy for improving the quality of life in the senescence]. Wiener medizinische Wochenschrift. Supplement. vol 98. 1987-01-05. PMID:3097965. |
the striatum, in which the nigrostriatal dopaminergic neurons terminate, contains the highest amount of dopamine da) in the brain. |
1987-01-05 |
2023-08-11 |
human |
| C Rauca, H Matthie. The effect of beta-casomorphins on the apomorphine- and amphetamine-induced turning after nigral lesions in rats. Neuropharmacology. vol 25. issue 10. 1987-01-02. PMID:3785581. |
the beta-casomorphins studied, (d-pro4-beta-casomorphin1-5, d-phe3-beta-casomorphin1-5, des-tyr1-d-pro4-beta-casomorphin2-5 or des-tyr1-d-phe3-beta-casomorphin2-5), did not change postsynaptic dopaminergic processes in the striatum of the rat after intraperitoneal injection of apomorphine. |
1987-01-02 |
2023-08-11 |
rat |
| C Rauca, H Matthie. The effect of beta-casomorphins on the apomorphine- and amphetamine-induced turning after nigral lesions in rats. Neuropharmacology. vol 25. issue 10. 1987-01-02. PMID:3785581. |
increased amphetamine-evoked turning could be observed after intrastriatal application of tyrosine-containing beta-casomorphins (d-pro4-beta-casomorphin1-5 or d-phe3-beta-casomorphin1-5), whereas presynaptic dopaminergic mechanisms were inhibited by injection of the corresponding des-tyrosine beta-casomorphin analogs (des-tyr1-d-pro4-beta-casomorphin2-5 or des-tyr1-d-phe3-beta-casomorphin2-5) into the striatum after administration of amphetamine. |
1987-01-02 |
2023-08-11 |
rat |
| M Traub, A Reches, H R Wagner, S Fah. Reserpine-induced up-regulation of dopamine D2 receptors in the rat striatum is enhanced by denervation but not by chronic receptor blockade. Neuroscience letters. vol 70. issue 2. 1986-12-18. PMID:2946007. |
compensatory increases in the density of dopamine (da) d2 receptors in the rat striatum occur following chronic interruption of dopaminergic neurotransmission. |
1986-12-18 |
2023-08-11 |
rat |
| G el Gemayel, J H Trouvin, M Prioux-Guyonneau, C Jacquot, Y Cohe. Dopaminergic metabolism in various rat brain areas after L-dopa loading. The Journal of pharmacy and pharmacology. vol 38. issue 9. 1986-12-17. PMID:2877071. |
after l-dopa loading, da, dopac and hva were increased in all the structures, but the largest increases were in those tissues with the less dopaminergic activity, while 3-mt increased in the hypothalamus, hippocampus and cerebellum but was lowered in striatum. |
1986-12-17 |
2023-08-11 |
rat |