| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Nakahara, K Doya, O Hikosak. Parallel cortico-basal ganglia mechanisms for acquisition and execution of visuomotor sequences - a computational approach. Journal of cognitive neuroscience. vol 13. issue 5. 2001-09-13. PMID:11506661. |
the concurrent learning in these loops is based on reinforcement signals carried by dopaminergic (da) neurons that project divergently to the anterior ("visual") and posterior ("motor") parts of the striatum. |
2001-09-13 |
2023-08-12 |
monkey |
| S T Rouse, M J Marino, S R Bradley, H Awad, M Wittmann, P J Con. Distribution and roles of metabotropic glutamate receptors in the basal ganglia motor circuit: implications for treatment of Parkinson's disease and related disorders. Pharmacology & therapeutics. vol 88. issue 3. 2001-09-06. PMID:11337032. |
most notably, the primary pathophysiological change that gives rise to the motor symptoms of parkinson's disease (pd) is the loss of dopaminergic neurons of the substantia nigra pars compacta (snc) that are involved in modulating function of the striatum and other bg structures. |
2001-09-06 |
2023-08-12 |
Not clear |
| H Frances, M Smirnova, A Leyris, N Aymard, J Bourr. Influence of social isolation and 6-OHDA lesion on the effects of quinelorane. Pharmacology, biochemistry, and behavior. vol 69. issue 1-2. 2001-09-06. PMID:11420079. |
the lesions of dopaminergic terminals with intracerebroventricular administration of 6-ohda decreased the dopamine (da) level by 93% in the nucleus accumbens and by 91% in the corpus striatum; these lesions impaired neither the hypolocomotion nor the hypothermia induced by quinelorane. |
2001-09-06 |
2023-08-12 |
mouse |
| K P Datla, S B Blunt, D T Dexte. Chronic L-DOPA administration is not toxic to the remaining dopaminergic nigrostriatal neurons, but instead may promote their functional recovery, in rats with partial 6-OHDA or FeCl(3) nigrostriatal lesions. Movement disorders : official journal of the Movement Disorder Society. vol 16. issue 3. 2001-08-16. PMID:11391735. |
l-dopa administration for 1 week produced an increase in the level of striatal rti-121 binding, a specific marker for dopamine uptake sites on the dopaminergic nerve terminals in the striatum. |
2001-08-16 |
2023-08-12 |
rat |
| P Calabresi, M Ammassari-Teule, P Gubellini, G Sancesario, M Morello, D Centonze, G A Marfia, E Saulle, E Passino, B Picconi, G Bernard. A synaptic mechanism underlying the behavioral abnormalities induced by manganese intoxication. Neurobiology of disease. vol 8. issue 3. 2001-08-16. PMID:11442351. |
these behavioral changes were associated with significantly increased brain mn levels but were uncoupled to anatomical lesions of the striatum or to morphological and cytochemical changes of the nigrostriatal dopaminergic pathway. |
2001-08-16 |
2023-08-12 |
rat |
| A Heller, N Bubula, R Lew, B Heller, L Wo. Gender-dependent enhanced adult neurotoxic response to methamphetamine following fetal exposure to the drug. The Journal of pharmacology and experimental therapeutics. vol 298. issue 2. 2001-08-09. PMID:11454941. |
this was evidenced by greater methamphetamine-induced reductions of dopaminergic markers in the striatum [dopamine (da), dihydroxyphenylacetic acid, homovanillic acid (hva), and 3-methoxytyramine (3-mt)] and ventral brainstem (da) of prenatal methamphetamine-treated males compared with saline-treated animals. |
2001-08-09 |
2023-08-12 |
Not clear |
| V P Chekhonin, V P Baklaushev, T B Dmitrieva, B M Kogan, E A Savchenko, S V Lebedev, I P Lazarenko, I V Man'kovskaya, T S Filatova, V V Belopaso. Complex analysis of efficiency of transplantation of embryonic nerve tissue to rats with hemiparkinsonism. Bulletin of experimental biology and medicine. vol 130. issue 12. 2001-08-02. PMID:11276317. |
dopaminergic neurons of the transplant survived, forming a network of tyrosine hydroxylase-positive processes growing beyond the transplant and reinnervating the adjacent compartments of the striatum. |
2001-08-02 |
2023-08-12 |
rat |
| V P Chekhonin, V P Baklaushev, T B Dmitrieva, B M Kogan, E A Savchenko, S V Lebedev, I P Lazarenko, I V Man'kovskaya, T S Filatova, V V Belopaso. Complex analysis of efficiency of transplantation of embryonic nerve tissue to rats with hemiparkinsonism. Bulletin of experimental biology and medicine. vol 130. issue 12. 2001-08-02. PMID:11276317. |
intrastriatal transplantation of cell preparations of embryonic striatum containing no dopaminergic neurons and isolated local injury to the striatum did not affect regeneration of the denervated nigrostratal system. |
2001-08-02 |
2023-08-12 |
rat |
| V I Petrov, V S Sergeyev, N V Onishchenk. The effect of N-acetyl-L-aspartic acid dilithium salt on dopamine release and synthesis in the rat striatum in vivo. European journal of pharmacology. vol 416. issue 1-2. 2001-07-26. PMID:11282114. |
the data suggest that availability of dilithium n-acetyl-l-aspartate to activate dopamine turnover and release in the rat striatum may be mediated by presynaptic nmda heteroreceptors located at dopaminergic neurons. |
2001-07-26 |
2023-08-12 |
rat |
| T Poyot, F Condé, M C Grégoire, V Frouin, C Coulon, C Fuseau, F Hinnen, F Dollé, P Hantraye, M Bottlaende. Anatomic and biochemical correlates of the dopamine transporter ligand 11C-PE2I in normal and parkinsonian primates: comparison with 6-[18F]fluoro-L-dopa. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 21. issue 7. 2001-07-26. PMID:11435790. |
in vivo 11c-pe2i b'max values correlated with 18f-dopa ki values and in vitro 125i-pe2i bmax values in the striatum and with the number of nigral dopaminergic neurons. |
2001-07-26 |
2023-08-12 |
Not clear |
| C L Parish, D I Finkelstein, J Drago, E Borrelli, M K Horn. The role of dopamine receptors in regulating the size of axonal arbors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 14. 2001-07-26. PMID:11438590. |
immunohistochemistry was performed, and the number of snpc neurons and dopaminergic terminals in the striatum was estimated. |
2001-07-26 |
2023-08-12 |
mouse |
| S J Kish, K S Kalasinsky, P Derkach, G A Schmunk, M Guttman, L Ang, V Adams, Y Furukawa, J W Haycoc. Striatal dopaminergic and serotonergic markers in human heroin users. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 24. issue 5. 2001-07-12. PMID:11282256. |
to establish whether chronic opiate exposure might impair brain dopaminergic or serotonergic function in humans, we assessed biochemical indices of monoaminergic neurotransmitter activity and integrity in post mortem striatum of nine chronic heroin users and 14 control subjects. |
2001-07-12 |
2023-08-12 |
human |
| W J Smeets, J M Lopez, A Gonzále. Immunohistochemical localization of DARPP-32 in the brain of the lizard, Gekko gecko: co-occurrence with tyrosine hydroxylase. The Journal of comparative neurology. vol 435. issue 2. 2001-07-12. PMID:11391641. |
in general, areas that are densely innervated by th-immunoreactive, putative dopaminergic fibers, such as the nucleus accumbens, striatum, dorsal ventricular ridge, and amygdaloid complex, display strong immunoreactivity for darpp-32 in somata and neuropil. |
2001-07-12 |
2023-08-12 |
Not clear |
| V Kaasinen, E Nurmi, A Brück, O Eskola, J Bergman, O Solin, J O Rinn. Increased frontal [(18)F]fluorodopa uptake in early Parkinson's disease: sex differences in the prefrontal cortex. Brain : a journal of neurology. vol 124. issue Pt 6. 2001-07-05. PMID:11353728. |
previous imaging studies in parkinson's disease have focused mainly on the striatum, a region with very high dopaminergic activity. |
2001-07-05 |
2023-08-12 |
human |
| A Natsume, M Mata, J Goss, S Huang, D Wolfe, T Oligino, J Glorioso, D J Fin. Bcl-2 and GDNF delivered by HSV-mediated gene transfer act additively to protect dopaminergic neurons from 6-OHDA-induced degeneration. Experimental neurology. vol 169. issue 2. 2001-07-05. PMID:11358438. |
previous studies have demonstrated that either the neurotrophin glial-derived neurotrophic factor (gdnf) or the antiapoptotic peptide bcl-2 delivered into striatum by a viral vector protects dopaminergic neurons of the substantia nigra in vivo from degeneration induced by the administration of the neurotoxin 6-hydroxydopamine (6-ohda). |
2001-07-05 |
2023-08-12 |
rat |
| N Törnqvist, L Björklund, I Strömber. Evidence for target-specific nerve fiber outgrowth from subpopulations of grafted dopaminergic neurons: a retrograde tracing study using in oculo and intracranial grafting. Experimental neurology. vol 169. issue 2. 2001-07-05. PMID:11358446. |
in conclusion, significantly more dopamine neurons projected to immature than to mature striatal tissue and thus, a subpopulation of grafted dopaminergic neurons was not projecting into adult striatum. |
2001-07-05 |
2023-08-12 |
Not clear |
| M Barrot, D N Abrous, M Marinelli, F Rougé-Pont, M Le Moal, P V Piazz. Influence of glucocorticoids on dopaminergic transmission in the rat dorsolateral striatum. The European journal of neuroscience. vol 13. issue 4. 2001-06-28. PMID:11207816. |
influence of glucocorticoids on dopaminergic transmission in the rat dorsolateral striatum. |
2001-06-28 |
2023-08-12 |
rat |
| M Barrot, D N Abrous, M Marinelli, F Rougé-Pont, M Le Moal, P V Piazz. Influence of glucocorticoids on dopaminergic transmission in the rat dorsolateral striatum. The European journal of neuroscience. vol 13. issue 4. 2001-06-28. PMID:11207816. |
in the present work, we examined the functional consequences of corticosterone suppression on the dopaminergic transmission in the dorsolateral striatum by studying the expression of fos-like proteins and extracellular dopamine levels. |
2001-06-28 |
2023-08-12 |
rat |
| M Barrot, D N Abrous, M Marinelli, F Rougé-Pont, M Le Moal, P V Piazz. Influence of glucocorticoids on dopaminergic transmission in the rat dorsolateral striatum. The European journal of neuroscience. vol 13. issue 4. 2001-06-28. PMID:11207816. |
we show that, in the dorsolateral striatum, glucocorticoids modify postsynaptic dopaminergic transmission. |
2001-06-28 |
2023-08-12 |
rat |
| W Maruyama, A A Boulton, B A Davis, P Dostert, M Nao. Enantio-specific induction of apoptosis by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopaminergic SH-SY5Y cells: suppression of apoptosis by N-(2-heptyl)-N-methylpropargylamine. Journal of neural transmission (Vienna, Austria : 1996). vol 108. issue 1. 2001-06-21. PMID:11261742. |
endogenous n-methyl(r)salsolinol, which caused parkinsonism in rats by injection in the striatum, was found to induce apoptosis in dopaminergic neuroblastoma sh-sy5y cells. |
2001-06-21 |
2023-08-12 |
rat |