| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J J Canales, C Capper-Loup, D Hu, E S Choe, U Upadhyay, A M Graybie. Shifts in striatal responsivity evoked by chronic stimulation of dopamine and glutamate systems. Brain : a journal of neurology. vol 125. issue Pt 10. 2002-10-29. PMID:12244091. |
by contrast, persistent stimulation of the motor cortex inhibits cocaine-stimulated signalling in the striatum, but not signalling mediated by individual dopamine receptor sites, suggesting that chronic cortical hyperexcitability produces long-term impairment of dopaminergic activity and compensation at the receptor level. |
2002-10-29 |
2023-08-12 |
rat |
| Z-H Feng, T-G Wang, D-D Li, P Fung, B C Wilson, B Liu, Syed F Ali, R Langenbach, J-S Hon. Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra. Neuroscience letters. vol 329. issue 3. 2002-10-28. PMID:12183047. |
these results indicate that loss of cox-2 activity reduces mptp-induced damage to the dopaminergic neurons of the snc, but does not alter the levels of dopamine and its metabolites in the striatum. |
2002-10-28 |
2023-08-12 |
mouse |
| Kazunori Adachi, Megumi Hasegawa, Satoshi Fujita, Michiko Sato, Yasuhiro Miwa, Hiroko Ikeda, Noriaki Koshikawa, Alexander R Cool. Dopaminergic and cholinergic stimulation of the ventrolateral striatum elicit rat jaw movements that are funnelled via distinct efferents. European journal of pharmacology. vol 442. issue 1-2. 2002-10-08. PMID:12020685. |
dopaminergic and cholinergic stimulation of the ventrolateral striatum elicit rat jaw movements that are funnelled via distinct efferents. |
2002-10-08 |
2023-08-12 |
rat |
| K S Raevskii, R R Gainetdinov, E A Budygin, P Mannisto, M Wightma. Dopaminergic transmission in the rat striatum in vivo in conditions of pharmacological modulation. Neuroscience and behavioral physiology. vol 32. issue 2. 2002-10-01. PMID:11942697. |
dopaminergic transmission in the rat striatum in vivo in conditions of pharmacological modulation. |
2002-10-01 |
2023-08-12 |
rat |
| Eva M Romero, Beatriz Fernández, Onintza Sagredo, Nuria Gomez, Leyre Urigüen, Carmen Guaza, Rosario De Miguel, Jose Antonio Ramos, M Paz Vivero. Antinociceptive, behavioural and neuroendocrine effects of CP 55,940 in young rats. Brain research. Developmental brain research. vol 136. issue 2. 2002-09-27. PMID:12101025. |
the cannabinoid agonist (0.6 mg/kg) induced a cb(1)-mediated increase in the serum corticosterone levels, but no effect on the dopaminergic systems of either the striatum or the limbic forebrain was found. |
2002-09-27 |
2023-08-12 |
rat |
| C Lo Bianco, J-L Ridet, B L Schneider, N Deglon, P Aebische. alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 16. 2002-09-23. PMID:12122208. |
in contrast to transgenic mice models, a selective loss of nigral dopaminergic neurons associated with a dopaminergic denervation of the striatum was observed in animals expressing either wild-type or mutant forms of human alpha-syn. |
2002-09-23 |
2023-08-12 |
mouse |
| Virginia M Pickel, Miguel Garzón, Elisa Mengua. Electron microscopic immunolabeling of transporters and receptors identifies transmitter-specific functional sites envisioned in Cajal's neuron. Progress in brain research. vol 136. 2002-09-19. PMID:12143378. |
dopamine terminals in the striatum and ventral pallidum, as well as dendrites of midbrain dopaminergic neurons in the ventral tegmental area and substantia nigra express the plasmalemmal dopamine transporter (dat) and the vesicular monoamine transporter (vmat2). |
2002-09-19 |
2023-08-12 |
Not clear |
| Guoping Cai, Hoau-Yan Wang, Eitan Friedma. Increased dopamine receptor signaling and dopamine receptor-G protein coupling in denervated striatum. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183669. |
chronic interruption of the nigrostriatal dopaminergic pathway leads to sensitized dopaminergic responses in striatum. |
2002-09-18 |
2023-08-12 |
rat |
| Guoping Cai, Hoau-Yan Wang, Eitan Friedma. Increased dopamine receptor signaling and dopamine receptor-G protein coupling in denervated striatum. The Journal of pharmacology and experimental therapeutics. vol 302. issue 3. 2002-09-18. PMID:12183669. |
the results provide an important molecular mechanism by which dopamine receptor-regulated signaling is enhanced following denervation of dopaminergic input to striatum. |
2002-09-18 |
2023-08-12 |
rat |
| Krishnan Sriram, Joanna M Matheson, Stanley A Benkovic, Diane B Miller, Michael I Luster, James P O'Callagha. Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 11. 2002-09-11. PMID:12205053. |
administration of mptp to wild-type (+/+) mice resulted in a time-dependent expression of tnf-alpha in striatum, which preceded the loss of dopaminergic markers and reactive gliosis. |
2002-09-11 |
2023-08-12 |
mouse |
| M Quik, Y Polonskaya, J M McIntosh, J M Kula. Differential nicotinic receptor expression in monkey basal ganglia: effects of nigrostriatal damage. Neuroscience. vol 112. issue 3. 2002-09-06. PMID:12074903. |
treatment with mptp, a neurotoxin that selectively destroys dopaminergic nigrostriatal neurons, led to a relatively uniform decrease in nicotinic receptor sites in the striatum, but a differential effect in the substantia nigra with significantly greater declines in the ventrolateral portion. |
2002-09-06 |
2023-08-12 |
monkey |
| M Quik, Y Polonskaya, J M McIntosh, J M Kula. Differential nicotinic receptor expression in monkey basal ganglia: effects of nigrostriatal damage. Neuroscience. vol 112. issue 3. 2002-09-06. PMID:12074903. |
from these data we suggest that in the striatum alpha3/alpha6 nicotinic receptors are primarily localized on dopaminergic nerve terminals, while multiple nicotinic receptor subtypes are present on dopaminergic cell bodies in the substantia nigra. |
2002-09-06 |
2023-08-12 |
monkey |
| Diego Centonze, Enrico Bracci, Antonio Pisani, Paolo Gubellini, Giorgio Bernardi, Paolo Calabres. Activation of dopamine D1-like receptors excites LTS interneurons of the striatum. The European journal of neuroscience. vol 15. issue 12. 2002-09-04. PMID:12099911. |
along with projection cells, striatal interneurons receive dense dopaminergic innervation from midbrain neurons, thus, also suggesting that these intrinsic cells represent a synaptic target for da action in the striatum. |
2002-09-04 |
2023-08-12 |
rat |
| D Chichung Lie, Gustavo Dziewczapolski, Andrew R Willhoite, Brian K Kaspar, Clifford W Shults, Fred H Gag. The adult substantia nigra contains progenitor cells with neurogenic potential. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 15. 2002-09-03. PMID:12151543. |
one current therapy aims at exogenous cellular replacement of dopaminergic function by transplanting fetal midbrain cells into the striatum, the main projection area of the sn. |
2002-09-03 |
2023-08-12 |
Not clear |
| A Hein. Dopaminergic dysfunction in alcoholism and schizophrenia--psychopathological and behavioral correlates. European psychiatry : the journal of the Association of European Psychiatrists. vol 17. issue 1. 2002-08-21. PMID:11918987. |
in the striatum, phasic dopamine release primarily affects motivation, psychomotor activation and reward craving, while in the prefrontal cortex, dopaminergic stimulation is involved in the activation of working memory and reward anticipation. |
2002-08-21 |
2023-08-12 |
Not clear |
| Aïcha Douhou, Thomas Debeir, Mario Gustavo Murer, Louis Do, Noëlle Dufour, Véronique Blanchard, Saliha Moussaoui, Georg Andrees Bohme, Yves Agid, Rita Raisman-Vozar. Effect of chronic treatment with riluzole on the nigrostriatal dopaminergic system in weaver mutant mice. Experimental neurology. vol 176. issue 1. 2002-08-16. PMID:12093102. |
quantification of tyrosine-hydroxylase and dopamine-transporter axonal immunostaining in the striatum revealed that riluzole significantly increased the density of striatal dopaminergic nerve terminals. |
2002-08-16 |
2023-08-12 |
mouse |
| Toshio Obat. Nitric oxide and depolarization induce hydroxyl radical generation. Japanese journal of pharmacology. vol 88. issue 1. 2002-08-15. PMID:11855667. |
abnormal levels of extracellular free dopamine (da) and/or intraneuronal ca2+ triggered by 1-methyl-4-phenylpyridinium ion (mpp+) may be detrimental to the functioning of dopaminergic nerve terminals in the striatum. |
2002-08-15 |
2023-08-12 |
Not clear |
| Rosalinda C Roberts, Michelle Force, Lili Kun. Dopaminergic synapses in the matrix of the ventrolateral striatum after chronic haloperidol treatment. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112400. |
dopaminergic synapses in the matrix of the ventrolateral striatum after chronic haloperidol treatment. |
2002-08-08 |
2023-08-12 |
rat |
| C Heim, L Sova, T Kurz, W Kolasiewicz, H Schwegler, K-H Sonta. Partial loss of dopaminergic neurons in the substantia nigra, ventrotegmental area and the retrorubral area -- model of the early beginning of Parkinson's symptomatology? Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111461. |
the application of tyrosine-hydroxylase-staining showed a loss of ipsilateral neurones of the substantia nigra compacta as well as of dendrites in the pars reticulata, neurones in the ventral tegmental area and in the retrorubral area ipsilaterally as well as a loss of dopaminergic fibres both ipsilaterally and contralaterally in the striatum which should belong to the contralateral acting substantia nigra afferents. |
2002-08-06 |
2023-08-12 |
rat |
| M Gerlach, W Ukai, H Ozawa, P Riedere. Different modes of action of catecholamine-O-methyltransferase inhibitors entacapone and tolcapone on adenylyl cyclase activity in vitro. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 5-6. 2002-08-06. PMID:12111468. |
the aim of this study was to examine the effects of the comt inhibitors entacapone and tolcapone on ac activity in membranes isolated from rat striatum, a brain structure enriched with dopaminergic g-protein-coupled receptors and ac activity. |
2002-08-06 |
2023-08-12 |
rat |