| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' T Reum, F Olshausen, T Mazel, I Vor\\xc3\\xadsek, R Morgenstern, E Sykov\\xc3\\xa. Diffusion parameters in the striatum of rats with 6-hydroxydopamine-induced lesions and with fetal mesencephalic grafts. Journal of neuroscience research. vol 70. issue 5. 2003-01-23. PMID:12424736.' |
functional recovery after transplantation of dopaminergic cells into the lesioned striatum is dependent on widespread diffusion of the transmitter released by the graft. |
2003-01-23 |
2023-08-12 |
rat |
| b' T Reum, F Olshausen, T Mazel, I Vor\\xc3\\xadsek, R Morgenstern, E Sykov\\xc3\\xa. Diffusion parameters in the striatum of rats with 6-hydroxydopamine-induced lesions and with fetal mesencephalic grafts. Journal of neuroscience research. vol 70. issue 5. 2003-01-23. PMID:12424736.' |
multiple but smaller graft deposits, in contrast to their enlarged capability for dopaminergic reinnervation, impair the conditions for diffusion and extrasynaptic transmission in a larger area of the striatum than do single macrografts, presumably because of more extensive tissue damage, cell loss, and astrogliosis. |
2003-01-23 |
2023-08-12 |
rat |
| Christoph Scherfler, Eveline Donnemiller, Michael Schocke, Katja Dierkes, Clemens Decristoforo, Michael Oberladstätter, Christian Kolbitsch, Fritz Zschiegner, Georg Riccabona, Werner Poewe, Gregor Wennin. Evaluation of striatal dopamine transporter function in rats by in vivo beta-[123I]CIT pinhole SPECT. NeuroImage. vol 17. issue 1. 2003-01-14. PMID:12482072. |
following estimation of the in vivo binding equilibrium of beta-[123i]cit in the healthy rat striatum, we evaluated the 6-hydroxydopamine-induced loss of striatal dat function using beta-[123i]cit spect and mri coregistration and correlated these findings with dopaminergic cell counts in the substantia nigra pars compacta using th immunohistochemistry. |
2003-01-14 |
2023-08-12 |
rat |
| Fu-Ming Zhou, Charles J Wilson, John A Dan. Cholinergic interneuron characteristics and nicotinic properties in the striatum. Journal of neurobiology. vol 53. issue 4. 2003-01-13. PMID:12436423. |
this process is among those in the striatum that link the two extensive and dense local arbors of the cholinergic interneurons and dopaminergic afferent fibers. |
2003-01-13 |
2023-08-12 |
Not clear |
| William F Maragos, Kristie L Young, Jadwiga T Turchan, Masha Guseva, James R Pauly, Avi Nath, Wayne A Cas. Human immunodeficiency virus-1 Tat protein and methamphetamine interact synergistically to impair striatal dopaminergic function. Journal of neurochemistry. vol 83. issue 4. 2002-12-24. PMID:12421368. |
the abuse of methamphetamine (ma), which is associated with behaviors that may transmit hiv-1, may damage dopaminergic afferents to the striatum. |
2002-12-24 |
2023-08-12 |
human |
| Yan Shen, Yi Yu, Hong Guo, Zhongshu Tang, Fu-Shin X Yu, Jiawei Zho. Identification and comparative analysis of differentially expressed proteins in rat striatum following 6-hydroxydopamine lesions of the nigrostriatal pathway: up-regulation of amyloid precursor-like protein 2 expression. The European journal of neuroscience. vol 16. issue 5. 2002-12-09. PMID:12372026. |
these results suggest that the expression of aplp2, a protein that has been thought to be associated with alzheimer's disease, is up-regulated in the striatum following dopaminergic denervation. |
2002-12-09 |
2023-08-12 |
rat |
| Jing Yu, Jean Lud Cadet, Jesus A Angul. Neurokinin-1 (NK-1) receptor antagonists abrogate methamphetamine-induced striatal dopaminergic neurotoxicity in the murine brain. Journal of neurochemistry. vol 83. issue 3. 2002-11-26. PMID:12390523. |
we tested the effects of the selective nk-1 receptor antagonists win-51,708 and l-733,060 on several markers of dopaminergic terminal toxicity in the mouse striatum. |
2002-11-26 |
2023-08-12 |
mouse |
| Matteo Marti, Flora Mela, Clementina Bianchi, Lorenzo Beani, Michele Morar. Striatal dopamine-NMDA receptor interactions in the modulation of glutamate release in the substantia nigra pars reticulata in vivo: opposite role for D1 and D2 receptors. Journal of neurochemistry. vol 83. issue 3. 2002-11-26. PMID:12390525. |
the physiopathological relevance of the dopaminergic modulation was strengthened by perfusing nmda in the dopamine-depleted striatum of hemiparkinsonian rats. |
2002-11-26 |
2023-08-12 |
rat |
| Michele Zoli, Milena Moretti, Alessio Zanardi, J Michael McIntosh, Francesco Clementi, Cecilia Gott. Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 20. 2002-11-25. PMID:12388584. |
identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum. |
2002-11-25 |
2023-08-12 |
rat |
| Michele Zoli, Milena Moretti, Alessio Zanardi, J Michael McIntosh, Francesco Clementi, Cecilia Gott. Identification of the nicotinic receptor subtypes expressed on dopaminergic terminals in the rat striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 20. 2002-11-25. PMID:12388584. |
further studies performed on 6-hydroxydopamine-lesioned striatum led to the identification of nachr subtypes selectively expressed on dopaminergic terminals [alpha4alpha5beta2, alpha4alpha6beta2(beta3), and alpha6beta2(beta3)], nondopaminergic neuronal structures (alpha2alpha4beta2), or both structures (alpha4beta2). |
2002-11-25 |
2023-08-12 |
rat |
| Douglas S Kim, Glenda J Froelick, Richard D Palmite. Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 22. 2002-11-18. PMID:12427840. |
dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum. |
2002-11-18 |
2023-08-12 |
mouse |
| Douglas S Kim, Glenda J Froelick, Richard D Palmite. Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 22. 2002-11-18. PMID:12427840. |
dopaminoceptive neurons appear to reduce their sensitivity to dopamine as dopaminergic terminals innervate the striatum and functional neurotransmission begins. |
2002-11-18 |
2023-08-12 |
mouse |
| Guy Drolet, Karine Proulx, Debra Pearson, Joseph Rochford, Christian F Descheppe. Comparisons of behavioral and neurochemical characteristics between WKY, WKHA, and Wistar rat strains. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225697. |
in situ hybridization for ngfi-b, a transcription factor related to the dopaminergic system, revealed that methylphenidate increased the expression of ngfi-b mrna in the accumbens (core/shell) and striatum only in wky rats. |
2002-11-15 |
2023-08-12 |
rat |
| Maddalena Napolitano, Diego Centonze, Angelica Calce, Barbara Picconi, Stefania Spiezia, Alberto Gulino, Giorgio Bernardi, Paolo Calabres. Experimental parkinsonism modulates multiple genes involved in the transduction of dopaminergic signals in the striatum. Neurobiology of disease. vol 10. issue 3. 2002-11-15. PMID:12270699. |
experimental parkinsonism modulates multiple genes involved in the transduction of dopaminergic signals in the striatum. |
2002-11-15 |
2023-08-12 |
rat |
| Z H Wang, Y Ji, W Shan, B Zeng, N Raksadawan, G M Pastores, T Wisniewski, E H Kolodn. Therapeutic effects of astrocytes expressing both tyrosine hydroxylase and brain-derived neurotrophic factor on a rat model of Parkinson's disease. Neuroscience. vol 113. issue 3. 2002-11-13. PMID:12150782. |
bdnf protected the dopaminergic neurons from apoptosis induced by 6-hydroxydopamine, and significantly increased the long-term survival of th-positive cells in the striatum. |
2002-11-13 |
2023-08-12 |
rat |
| N Pavón-Fuentes, R Macías-González, L Blanco-Lezcano, L Alvarez-González, L Martínez-Martí, L Castillo-Díaz, K De La Cuétara Bernal, C Díaz, L Lorigados-Pedre, Y Coro, A Y García-Varona, J C Rosillo, E Día. [Effects of simultaneous transplant of foetal mesencephalic cells in the striatum and the subthalamic nucleus of hemiparkinsonian rats]. Revista de neurologia. vol 34. issue 10. 2002-11-12. PMID:12134319. |
however, when the dopaminergic cells in the substantia nigra degenerate, not only is the dopaminergic innervation of the striatum affected but also other nuclei: globus pallidus, substantia nigra, substantia nigra pars reticulata and subthalamic nucleus. |
2002-11-12 |
2023-08-12 |
rat |
| I Kanazaw. [On what I learned from researches on Huntington's disease]. Rinsho shinkeigaku = Clinical neurology. vol 41. issue 12. 2002-11-08. PMID:12235789. |
in the middle 16-17 years, i preferentially worked in the field of neurochemical pharmacology, suggesting a mechanism of chorea in hd to be a result of hyperactivity of remaining presynaptic dopaminergic system in the striatum by making a 'choreic' model in monkey using excitotoxic kainic acid and levodopa. |
2002-11-08 |
2023-08-12 |
human |
| Yoshitsugu Oiwa, Ryo Yoshimura, Kunio Nakai, Toru Itakur. Dopaminergic neuroprotection and regeneration by neurturin assessed by using behavioral, biochemical and histochemical measurements in a model of progressive Parkinson's disease. Brain research. vol 947. issue 2. 2002-10-30. PMID:12176170. |
however, th-immunoreactive fibers were thicker and more abundant in the striatum of the neurturin-treated rats compared to those of the control group, suggesting neurturin-induced growth of the dopaminergic axons. |
2002-10-30 |
2023-08-12 |
human |
| Richard Grondin, Zhiming Zhang, Ai Yi, Wayne A Cass, Navin Maswood, Anders H Andersen, Dennis D Elsberry, Michael C Klein, Greg A Gerhardt, Don M Gas. Chronic, controlled GDNF infusion promotes structural and functional recovery in advanced parkinsonian monkeys. Brain : a journal of neurology. vol 125. issue Pt 10. 2002-10-29. PMID:12244077. |
here we demonstrate that the chronic infusion of 5 or 15 micro g/day gdnf into the lateral ventricle or the striatum, using programmable pumps, promotes restoration of the nigrostriatal dopaminergic system and significantly improves motor functions in rhesus monkeys with neural deficits modelling the terminal stages of parkinson's disease. |
2002-10-29 |
2023-08-12 |
monkey |
| J J Canales, C Capper-Loup, D Hu, E S Choe, U Upadhyay, A M Graybie. Shifts in striatal responsivity evoked by chronic stimulation of dopamine and glutamate systems. Brain : a journal of neurology. vol 125. issue Pt 10. 2002-10-29. PMID:12244091. |
reciprocally, we studied the effects of chronic intermittent motor cortex stimulation on the capacity for subsequent acute dopaminergic treatments to induce early-gene activation in the striatum. |
2002-10-29 |
2023-08-12 |
rat |