| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Iometopane: (123)I beta-CIT, dopascan injection, GPI 200, RTI 55. Drugs in R&D. vol 4. issue 5. 2004-03-15. PMID:12952503. |
the ability of iometopane to bind to the dopamine transporter on presynaptic dopaminergic nerve terminal in the striatum (caudate nucleus and putamen) has been used to differentiate the uptake of the agent by the neurons in the striatum in patients with a parkinsonian disorder (parkinson's disease and progressive supranuclear palsy) from patients without a parkinsonian disorder (essential tremor and healthy controls) with high sensitivity and specificity. |
2004-03-15 |
2023-08-12 |
Not clear |
| M Lonjon, M H Quentien, J J Risso, J F Michiels, E Carre, J C Rostain, O Darbi. Alteration of striatal dopaminergic function induced by glioma development: a microdialysis and immunohistological study in the rat striatum. Neuroscience letters. vol 354. issue 2. 2004-03-11. PMID:14698456. |
alteration of striatal dopaminergic function induced by glioma development: a microdialysis and immunohistological study in the rat striatum. |
2004-03-11 |
2023-08-12 |
rat |
| Abraham A Palmer, David J Printz, Pamela D Butler, Stephanie C Dulawa, Morton P Print. Prenatal protein deprivation in rats induces changes in prepulse inhibition and NMDA receptor binding. Brain research. vol 996. issue 2. 2004-03-10. PMID:14697497. |
additionally, we examined dopaminergic and glutaminergic receptor binding in the striatum and hippocampus, which have been suggested to play a role in the etiology of schizophrenia. |
2004-03-10 |
2023-08-12 |
rat |
| b' Aleksandra Mladenovi\\xc4\\x87, Milka Perovi\\xc4\\x87, Nevena Raicevi\\xc4\\x87, Selma Kanazir, Ljubisav Raki\\xc4\\x87, Sabera Ruzdiji\\xc4\\x8. 6-Hydroxydopamine increases the level of TNFalpha and bax mRNA in the striatum and induces apoptosis of dopaminergic neurons in hemiparkinsonian rats. Brain research. vol 996. issue 2. 2004-03-10. PMID:14697501.' |
6-hydroxydopamine increases the level of tnfalpha and bax mrna in the striatum and induces apoptosis of dopaminergic neurons in hemiparkinsonian rats. |
2004-03-10 |
2023-08-12 |
rat |
| David Pubill, Anna M Canudas, Mercè Pallàs, Antonio Camins, Jorge Camarasa, Elena Escubed. Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity. Naunyn-Schmiedeberg's archives of pharmacology. vol 367. issue 5. 2004-03-02. PMID:12684743. |
methamphetamine (four injections of 10 mg kg(-1) s.c. at 2-h intervals) induced the loss of dopaminergic (35%) but not of serotonergic, terminals in the rat striatum and, simultaneously, a significant increase in striatal peripheral-type benzodiazepine receptor density, pointing to a glial reaction. |
2004-03-02 |
2023-08-12 |
rat |
| David Pubill, Anna M Canudas, Mercè Pallàs, Antonio Camins, Jorge Camarasa, Elena Escubed. Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity. Naunyn-Schmiedeberg's archives of pharmacology. vol 367. issue 5. 2004-03-02. PMID:12684743. |
for 4 days) induced a similar dopaminergic lesion in the striatum 3 days post-treatment, which reversed 4 days later. |
2004-03-02 |
2023-08-12 |
rat |
| Kazuhiko Yanamoto, Rie Hosoi, Yumi Uesaka, Kohji Abe, Hideo Tsukada, Osamu Inou. Intrastriatal microinjection of sodium nitroprusside induces cell death and reduces binding of dopaminergic receptors. Synapse (New York, N.Y.). vol 50. issue 2. 2004-02-24. PMID:12923816. |
rat striatum was microinjected with 50 nmol sodium nitroprusside (snp) and neural cell death as well as the binding of dopaminergic receptors were followed for 24 h after the infusion using ttc staining, cresyl violet staining, and quantitative autoradiography. |
2004-02-24 |
2023-08-12 |
rat |
| Kazuhiko Yanamoto, Rie Hosoi, Yumi Uesaka, Kohji Abe, Hideo Tsukada, Osamu Inou. Intrastriatal microinjection of sodium nitroprusside induces cell death and reduces binding of dopaminergic receptors. Synapse (New York, N.Y.). vol 50. issue 2. 2004-02-24. PMID:12923816. |
one day after the infusion, less than 10% of the binding of all three types of dopaminergic receptors remained in a widespread area in the infused side of the striatum and part of the cerebral cortex. |
2004-02-24 |
2023-08-12 |
rat |
| M Quik, T Bordia, L Forno, J M McIntos. Loss of alpha-conotoxinMII- and A85380-sensitive nicotinic receptors in Parkinson's disease striatum. Journal of neurochemistry. vol 88. issue 3. 2004-02-24. PMID:14720216. |
correlation analyses between changes in nicotinic receptors and the dopamine transporter in parkinson's disease striatum suggest that alpha-conotoxinmii-sensitive 125i-epibatidine sites (low-affinity sites), 125i-a85380 and 125i-epibatidine sites are localized in part to dopaminergic terminals. |
2004-02-24 |
2023-08-12 |
human |
| Jette Bisgaard Boll, Marie Aavang Geist, Gabriele S Kaminski Schierle, Karina Petersen, Marcel Leist, Elisabetta Vaudan. Improvement of embryonic dopaminergic neurone survival in culture and after grafting into the striatum of hemiparkinsonian rats by CEP-1347. Journal of neurochemistry. vol 88. issue 3. 2004-02-24. PMID:14720219. |
improvement of embryonic dopaminergic neurone survival in culture and after grafting into the striatum of hemiparkinsonian rats by cep-1347. |
2004-02-24 |
2023-08-12 |
human |
| Jette Bisgaard Boll, Marie Aavang Geist, Gabriele S Kaminski Schierle, Karina Petersen, Marcel Leist, Elisabetta Vaudan. Improvement of embryonic dopaminergic neurone survival in culture and after grafting into the striatum of hemiparkinsonian rats by CEP-1347. Journal of neurochemistry. vol 88. issue 3. 2004-02-24. PMID:14720219. |
moreover, combined treatment of the grafting cell suspension and the host animal with cep-1347 significantly improved the long-term survival of rat dopaminergic neurones transplanted into the striatum of hemiparkinsonian rats. |
2004-02-24 |
2023-08-12 |
human |
| Anthone W Dunah, Ana C Sirianni, Allen A Fienberg, Elena Bastia, Michael A Schwarzschild, David G Standaer. Dopamine D1-dependent trafficking of striatal N-methyl-D-aspartate glutamate receptors requires Fyn protein tyrosine kinase but not DARPP-32. Molecular pharmacology. vol 65. issue 1. 2004-02-18. PMID:14722243. |
interactions between dopaminergic and glutamatergic systems in the striatum are thought to underlie both the symptoms and adverse effects of treatment of parkinson's disease. |
2004-02-18 |
2023-08-12 |
mouse |
| M F Kritzer, A Adler, C L Bethe. Ovarian hormone influences on the density of immunoreactivity for tyrosine hydroxylase and serotonin in the primate corpus striatum. Neuroscience. vol 122. issue 3. 2004-02-17. PMID:14622919. |
the serotonergic and dopaminergic inputs to the corpus striatum in human and non-human primates participate in diverse sensorimotor, cognitive, and affective functions, are implicated in dysfunction in diseases such as parkinson's disease and schizophrenia, and are targets for many of the drugs used to treat these disorders. |
2004-02-17 |
2023-08-12 |
human |
| Thomas Dehmer, Michael T Heneka, Magdalena Sastre, Johannes Dichgans, Jörg B Schul. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. Journal of neurochemistry. vol 88. issue 2. 2004-02-17. PMID:14690537. |
we here investigated whether pioglitazone, a ppargamma agonist, protected mice from mptp-induced dopaminergic cell loss, glial activation, and loss of catecholamines in the striatum. |
2004-02-17 |
2023-08-12 |
mouse |
| Pierre Champy, Günter U Höglinger, Jean Féger, Christophe Gleye, Reynald Hocquemiller, Alain Laurens, Vincent Guérineau, Olivier Laprévote, Fadia Medja, Anne Lombès, Patrick P Michel, Annie Lannuzel, Etienne C Hirsch, Merle Ruber. Annonacin, a lipophilic inhibitor of mitochondrial complex I, induces nigral and striatal neurodegeneration in rats: possible relevance for atypical parkinsonism in Guadeloupe. Journal of neurochemistry. vol 88. issue 1. 2004-01-29. PMID:14675150. |
stereological cell counts showed significant loss of dopaminergic neurones in the substantia nigra (-31.7%), and cholinergic (-37.9%) and dopamine and cyclic amp-regulated phosphoprotein (darpp-32)-immunoreactive gabaergic neurones (-39.3%) in the striatum, accompanied by a significant increase in the number of astrocytes (35.4%) and microglial cells (73.4%). |
2004-01-29 |
2023-08-12 |
rat |
| Valérie Cochen, Maria-Joao Ribeiro, Jean-Paul Nguyen, Jean-Marc Gurruchaga, Gabriel Villafane, Christian Loc'h, Gilles Defer, Yves Samson, Marc Peschanski, Philippe Hantraye, Pierre Cesaro, Philippe Rem. Transplantation in Parkinson's disease: PET changes correlate with the amount of grafted tissue. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 8. 2004-01-28. PMID:12889084. |
this finding suggests that the clinical benefit induced by the graft is more related to increased dopaminergic activity than improved dopaminergic innervation in the host striatum and, therefore, that [(18)f]fluorodopa remains the optimal tracer to evaluate grafted pd patients. |
2004-01-28 |
2023-08-12 |
Not clear |
| Marta Barrachina, Isabel Domínguez, Santiago Ambrosio, Julio Secades, Rafael Lozano, Isidro Ferre. Neuroprotective effect of citicoline in 6-hydroxydopamine-lesioned rats and in 6-hydroxydopamine-treated SH-SY5Y human neuroblastoma cells. Journal of the neurological sciences. vol 215. issue 1-2. 2004-01-20. PMID:14568136. |
finally, citicoline significantly attenuates substantia nigra (sn) dopaminergic cell dropout and tyrosine hydroxylase immunoreactivity in the ipsilateral striatum in rats injected intrastriatally with 6-hydroxydopamine (6-ohda). |
2004-01-20 |
2023-08-12 |
human |
| Lisa Won, Nancy Bubula, Suzanne Hessefort, Martin Gross, Alfred Helle. Enhanced survival of primary murine dopaminergic neurons induced by a partially purified cell lysate fraction from mouse-derived striatal hybrid monoclonal cells. Neuroscience letters. vol 353. issue 2. 2004-01-16. PMID:14664906. |
the results suggest that the activity factor derived from x61 is capable of preventing dopaminergic cell loss which occurs in the absence of dopaminergic target cells of the corpus striatum. |
2004-01-16 |
2023-08-12 |
Not clear |
| Joshua T Dudman, Molly E Eaton, Anjali Rajadhyaksha, Wendy Macías, Muffadal Taher, Amy Barczak, Kimihiko Kameyama, Richard Huganir, Christine Konrad. Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1. Journal of neurochemistry. vol 87. issue 4. 2004-01-14. PMID:14622123. |
addictive drugs such as amphetamine and cocaine stimulate the dopaminergic system, activate dopamine receptors and induce gene expression throughout the striatum. |
2004-01-14 |
2023-08-12 |
Not clear |
| C Bishop, P D Walke. Combined intrastriatal dopamine D1 and serotonin 5-HT2 receptor stimulation reveals a mechanism for hyperlocomotion in 6-hydroxydopamine-lesioned rats. Neuroscience. vol 121. issue 3. 2004-01-09. PMID:14568025. |
loss of dopaminergic innervation to the striatum increases the sensitivity of dopamine (da) d1 and serotonin (5-ht) 5-ht2 receptor signaling. |
2004-01-09 |
2023-08-12 |
human |