| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kunio Yui, Shigenori Ikemot. [Stress sensitization induced by stressor and methamphetamine]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 24. issue 3. 2004-08-16. PMID:15291245. |
striatum, nucleus accumbens and prefrontal dopaminergic systems have an important role in the development of this sensitization. |
2004-08-16 |
2023-08-12 |
Not clear |
| Bertrand Bloch, Véronique Bernard, Brigitte Dumarti. "In vivo" intraneuronal trafficking of G protein coupled receptors in the striatum: regulation by dopaminergic and cholinergic environment. Biology of the cell. vol 95. issue 7. 2004-07-30. PMID:14597266. |
"in vivo" intraneuronal trafficking of g protein coupled receptors in the striatum: regulation by dopaminergic and cholinergic environment. |
2004-07-30 |
2023-08-12 |
Not clear |
| Alberto Del Arco, Shunwei Zhu, Anton Terasmaa, Abdul H Mohammed, Kjell Fux. Hyperactivity to novelty induced by social isolation is not correlated with changes in D2 receptor function and binding in striatum. Psychopharmacology. vol 171. issue 2. 2004-07-27. PMID:13680076. |
while these behavioral changes have been partly related to a dysregulation of dopaminergic activity in striatum (dorsal and ventral), the involvement of changes in the function of dopamine receptors is still a matter of controversy. |
2004-07-27 |
2023-08-12 |
Not clear |
| Wen-Sheng Huang, Meei-Shyuan Lee, Jiann-Chyun Lin, Cheng-Yu Chen, Yu-Wen Yang, Shinn-Zong Lin, Shiaw-Pyng We. Usefulness of brain 99mTc-TRODAT-1 SPET for the evaluation of Parkinson's disease. European journal of nuclear medicine and molecular imaging. vol 31. issue 2. 2004-07-23. PMID:15129696. |
nigral dopaminergic projections to the striatum are targeted in parkinson's disease (pd). |
2004-07-23 |
2023-08-12 |
Not clear |
| Ali Sajadi, Bernard L Schneider, Patrick Aebische. Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease. Current biology : CB. vol 14. issue 4. 2004-07-20. PMID:14972684. |
parkinson disease (pd) is characterized by the progressive degeneration of substantia nigra dopaminergic neurons projecting to the striatum. |
2004-07-20 |
2023-08-12 |
mouse |
| J L W Bosboom, E Ch Wolter. Psychotic symptoms in Parkinson's disease: pathophysiology and management. Expert opinion on drug safety. vol 3. issue 3. 2004-07-13. PMID:15155149. |
parkinson's disease (pd) is a chronic neurodegenerative disease, in which mainly dopaminergic neurons in the substantia nigra in the brain degenerate, leading to a depletion of dopamine (da) in the striatum. |
2004-07-13 |
2023-08-12 |
Not clear |
| Javier A W Opezzo, Christian Höcht, Carlos A Tair. Pharmacokinetic profile of methyldopa in the brain of sinaortic-denervated rats. Pharmacological research. vol 48. issue 1. 2004-07-09. PMID:12770516. |
in conclusion, this study by using a microdialysis technique shows that md has different kinetic profiles in dialysates from posterior hypothalamus and striatum of so and sad rats at a dose that alters dopaminergic metabolism. |
2004-07-09 |
2023-08-12 |
rat |
| Akinori Iwashita, Syunji Yamazaki, Kayoko Mihara, Kouji Hattori, Hirofumi Yamamoto, Junya Ishida, Nobuya Matsuoka, Seitaro Muto. Neuroprotective effects of a novel poly(ADP-ribose) polymerase-1 inhibitor, 2-[3-[4-(4-chlorophenyl)-1-piperazinyl] propyl]-4(3H)-quinazolinone (FR255595), in an in vitro model of cell death and in mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of pharmacology and experimental therapeutics. vol 309. issue 3. 2004-07-01. PMID:14985416. |
intoxication lead to parp activation and cell damage in the nigrostriatal dopaminergic pathway, which was significantly ameliorated by oral administration of fr255595 (10-32 mg/kg), both in the substantia nigra and in the striatum via marked reduction of parp activation, even with delayed treatment. |
2004-07-01 |
2023-08-12 |
mouse |
| Rivelilson Mendes Freitas, Cícero F Bezerra Felipe, Viviane S Nascimento, Aline A Oliveira, Glauce S B Viana, Marta Maria de F Fontele. Pilocarpine-induced seizures in adult rats: monoamine content and muscarinic and dopaminergic receptor changes in the striatum. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 136. issue 2. 2004-06-28. PMID:14559291. |
pilocarpine-induced seizures in adult rats: monoamine content and muscarinic and dopaminergic receptor changes in the striatum. |
2004-06-28 |
2023-08-12 |
rat |
| Rivelilson Mendes Freitas, Cícero F Bezerra Felipe, Viviane S Nascimento, Aline A Oliveira, Glauce S B Viana, Marta Maria de F Fontele. Pilocarpine-induced seizures in adult rats: monoamine content and muscarinic and dopaminergic receptor changes in the striatum. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 136. issue 2. 2004-06-28. PMID:14559291. |
pilocarpine (400 mg/kg; subcutaneously) was administered in 2-month-old female rats, and the content of striatum monoamines and (m(1)+m(2)) muscarinic and d(2) dopaminergic receptors was measured in the acute period. |
2004-06-28 |
2023-08-12 |
rat |
| Hiroaki Matsubayashi, Taku Amano, Takahiro Seki, Masashi Sasa, Norio Saka. Electrophysiological characterization of nicotine-induced excitation of dopaminergic neurons in the rat substantia nigra. Journal of pharmacological sciences. vol 93. issue 2. 2004-06-18. PMID:14578581. |
nicotine directly acts on postsynaptic alpha4beta2 type nicotinic receptors and induces inward currents, resulting in excitation of dopaminergic neurons in the substantia nigra and subsequent enhancement of dopamine release in the corpus striatum. |
2004-06-18 |
2023-08-12 |
rat |
| Anthony J Baucum, Kristi S Rau, Evan L Riddle, Glen R Hanson, Annette E Fleckenstei. Methamphetamine increases dopamine transporter higher molecular weight complex formation via a dopamine- and hyperthermia-associated mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 13. 2004-06-18. PMID:15056723. |
multiple high-dose administrations of methamphetamine (meth) both rapidly (within hours) decrease plasmalemmal dopamine (da) uptake and cause long-term deficits in da transporter (dat) levels and other dopaminergic parameters persisting weeks to months in rat striatum. |
2004-06-18 |
2023-08-12 |
rat |
| Jean-Marc Taymans, Hossein Kami Kia, Robby Claes, Catarina Cruz, Josée Leysen, Xavier Langloi. Dopamine receptor-mediated regulation of RGS2 and RGS4 mRNA differentially depends on ascending dopamine projections and time. The European journal of neuroscience. vol 19. issue 8. 2004-06-18. PMID:15090051. |
rgs2 and rgs4 mrnas are regulated in the rat striatum by dopaminergic agents. |
2004-06-18 |
2023-08-12 |
rat |
| Nikolai Kholodilov, Olga Yarygina, Tinmarla Frances Oo, Hui Zhang, David Sulzer, William Dauer, Robert E Burk. Regulation of the development of mesencephalic dopaminergic systems by the selective expression of glial cell line-derived neurotrophic factor in their targets. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 12. 2004-06-10. PMID:15044553. |
as adults, these mice also do not have increased dopaminergic innervation of the striatum. |
2004-06-10 |
2023-08-12 |
mouse |
| Valtteri Kaasinen, Sargo Aalto, Kjell Någren, Juha O Rinn. Dopaminergic effects of caffeine in the human striatum and thalamus. Neuroreport. vol 15. issue 2. 2004-06-10. PMID:15076753. |
dopaminergic effects of caffeine in the human striatum and thalamus. |
2004-06-10 |
2023-08-12 |
human |
| Valtteri Kaasinen, Sargo Aalto, Kjell Någren, Juha O Rinn. Dopaminergic effects of caffeine in the human striatum and thalamus. Neuroreport. vol 15. issue 2. 2004-06-10. PMID:15076753. |
the findings indicate that caffeine has effects on dopaminergic neurotransmission in the human brain, which may be differential in the striatum and the thalamus. |
2004-06-10 |
2023-08-12 |
human |
| Emilio Fernandez-Espej. Pathogenesis of Parkinson's disease: prospects of neuroprotective and restorative therapies. Molecular neurobiology. vol 29. issue 1. 2004-06-04. PMID:15034220. |
parkinson's disease (pd) is caused by the degeneration of dopaminergic neurons of substantia nigra projecting to striatum. |
2004-06-04 |
2023-08-12 |
rat |
| F Delis, A Mitsacos, P Giompre. Dopamine receptor and transporter levels are altered in the brain of Purkinje Cell Degeneration mutant mice. Neuroscience. vol 125. issue 1. 2004-06-03. PMID:15051164. |
the dopamine transporters, as determined by [3h]win35428 binding, were increased compared with wild-type mice in the ventral mesencephalic dopaminergic nuclei and in the lateral striatum, motor cortex and septum. |
2004-06-03 |
2023-08-12 |
mouse |
| Wei Zhang, Tongguang Wang, Liya Qin, Hui-Ming Gao, Belinda Wilson, Syed F Ali, Wanqin Zhang, Jau-Shyong Hong, Bin Li. Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 3. 2004-06-01. PMID:14734632. |
parkinson's disease (pd) is a neurodegenerative movement disorder characterized by a progressive loss of dopaminergic neurons in the substantia nigra and depletion of the neurotransmitter dopamine in the striatum. |
2004-06-01 |
2023-08-12 |
mouse |
| Olle Lindval. Stem cells for cell therapy in Parkinson's disease. Pharmacological research. vol 47. issue 4. 2004-05-21. PMID:12644384. |
the grafted dopaminergic neurons can reinnervate the denervated striatum, restore regulated dopamine (da) release and movement-related frontal cortical activation, and give rise to significant symptomatic relief. |
2004-05-21 |
2023-08-12 |
human |