| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Akaneya, M Takahashi, H Hatanak. Survival of and 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501301. |
survival of and 1-methyl-4-phenylpyridinium (mpp+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. |
1996-01-18 |
2023-08-12 |
rat |
| Y Akaneya, M Takahashi, H Hatanak. Survival of and 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501301. |
it is known that dopaminergic neurons in the substantia nigra of the mesencephalon mainly project to the corpus striatum and neocortex, while the hippocampus receives major cholinergic projection from the septum. |
1996-01-18 |
2023-08-12 |
rat |
| Y Akaneya, M Takahashi, H Hatanak. Survival of and 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501301. |
in the present study, the ventral mesencephalon was cocultured with target regions of its dopaminergic neurons, the striatum and neocortex, and with non-target regions, the hippocampus, thalamus, colliculus and cerebellum, using embryonic day-17 (e17) rats. |
1996-01-18 |
2023-08-12 |
rat |
| Y Akaneya, M Takahashi, H Hatanak. Survival of and 1-methyl-4-phenylpyridinium (MPP+) neurotoxicity against dopaminergic neurons in coculture of rat mesencephalon with their target on non-target regions. Neuroscience research. vol 23. issue 1. 1996-01-18. PMID:7501301. |
these findings suggest that putative factor(s), possibly target-derived neurotrophic factor(s), emerging from the regions cocultured with ventral mesencephalon can influence the dopaminergic neurons resulting in the augmentation of survival. |
1996-01-18 |
2023-08-12 |
rat |
| H Okamura, C Yokoyama, Y Ibat. Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. Experimental neurology. vol 136. issue 2. 1996-01-17. PMID:7498403. |
lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. |
1996-01-17 |
2023-08-12 |
Not clear |
| H Okamura, C Yokoyama, Y Ibat. Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. Experimental neurology. vol 136. issue 2. 1996-01-17. PMID:7498403. |
the topography-dependent vulnerability of midbrain dopaminergic neurons to neonatal intracranial exposure to 6-hydroxydopamine (6-ohda) was investigated at adult age by the quantitative analysis of cell counts of tyrosine hydroxylase-immunopositive neurons. |
1996-01-17 |
2023-08-12 |
Not clear |
| H Okamura, C Yokoyama, Y Ibat. Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. Experimental neurology. vol 136. issue 2. 1996-01-17. PMID:7498403. |
in the a10 neuronal group, cells located in the medial part of the ventral tegmental area were more resistant to toxicity than those located more laterally, and dopaminergic cells in the midline midbrain areas (interfascicular nucleus and rostral linear nucleus of raphe) were completely spared from 6-ohda toxicity. |
1996-01-17 |
2023-08-12 |
Not clear |
| H Okamura, C Yokoyama, Y Ibat. Lateromedial gradient of the susceptibility of midbrain dopaminergic neurons to neonatal 6-hydroxydopamine toxicity. Experimental neurology. vol 136. issue 2. 1996-01-17. PMID:7498403. |
these findings revealed that 6-ohda is not equally toxic to all midbrain dopaminergic neurons in neonates and that the lateromedial vulnerability pattern shows similarities to those reported in parkinson's disease. |
1996-01-17 |
2023-08-12 |
Not clear |
| M Z Wang, P Jin, D A Bumcrot, V Marigo, A P McMahon, E A Wang, T Woolf, K Pan. Induction of dopaminergic neuron phenotype in the midbrain by Sonic hedgehog protein. Nature medicine. vol 1. issue 11. 1995-12-28. PMID:7584992. |
loss of substantia nigra dopaminergic neurons, which develop from the ventral region of the midbrain, is associated with parkinson's disease. |
1995-12-28 |
2023-08-12 |
chicken |
| A Buj-Bello, V L Buchman, A Horton, A Rosenthal, A M Davie. GDNF is an age-specific survival factor for sensory and autonomic neurons. Neuron. vol 15. issue 4. 1995-12-06. PMID:7576631. |
glial cell line-derived neurotrophic factor (gdnf) promotes the survival of two populations of cns neurons: motoneurons and midbrain dopaminergic neurons. |
1995-12-06 |
2023-08-12 |
chicken |
| B A Faucheux, N Nillesse, P Damier, G Spik, A Mouatt-Prigent, A Pierce, B Leveugle, N Kubis, J J Hauw, Y Agi. Expression of lactoferrin receptors is increased in the mesencephalon of patients with Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 21. 1995-11-14. PMID:7568181. |
in parkinsonian patients, lactoferrin receptor immunoreactivity on neurons and microvessels was increased and more pronounced in those regions of the mesencephalon where the loss of dopaminergic neurons is severe. |
1995-11-14 |
2023-08-12 |
human |
| H T Mount, D O Dean, J Alberch, C F Dreyfus, I B Blac. Glial cell line-derived neurotrophic factor promotes the survival and morphologic differentiation of Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 20. 1995-10-27. PMID:7568079. |
glial cell line-derived neurotrophic factor (gdnf) promotes survival of midbrain dopaminergic neurons and motoneurons. |
1995-10-27 |
2023-08-12 |
rat |
| S A Oakman, P L Faris, P E Kerr, C Cozzari, B K Hartma. Distribution of pontomesencephalic cholinergic neurons projecting to substantia nigra differs significantly from those projecting to ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 9. 1995-10-12. PMID:7666171. |
locations of pontomesencephalic cholinergic projection neurons from the laterodorsal tegmental (ldtg) and pedunculopontine tegmental (pptg) nuclei to midbrain dopaminergic nuclei were mapped. |
1995-10-12 |
2023-08-12 |
rat |
| A Tomac, J Widenfalk, L F Lin, T Kohno, T Ebendal, B J Hoffer, L Olso. Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 18. 1995-10-12. PMID:7667281. |
however, evidence for a role for endogenous gdnf as a target-derived trophic factor in adult midbrain dopaminergic circuits requires documentation of specific transport from the sites of synthesis in the target areas to the nerve cell bodies themselves. |
1995-10-12 |
2023-08-12 |
Not clear |
| H Kawano, K Ohyama, K Kawamura, I Nagats. Migration of dopaminergic neurons in the embryonic mesencephalon of mice. Brain research. Developmental brain research. vol 86. issue 1-2. 1995-10-05. PMID:7544698. |
migration of dopaminergic neurons in the embryonic mesencephalon of mice. |
1995-10-05 |
2023-08-12 |
mouse |
| M Ishimaru, T Hashimoto, K Obata, F Fukamauch. Methamphetamine-induced dopaminergic hyperactivity is not accompanied with increase in tyrosine hydroxylase mRNA of the rat midbrain. Neuroscience letters. vol 191. issue 1-2. 1995-09-29. PMID:7659275. |
methamphetamine-induced dopaminergic hyperactivity is not accompanied with increase in tyrosine hydroxylase mrna of the rat midbrain. |
1995-09-29 |
2023-08-12 |
rat |
| M Ishimaru, T Hashimoto, K Obata, F Fukamauch. Methamphetamine-induced dopaminergic hyperactivity is not accompanied with increase in tyrosine hydroxylase mRNA of the rat midbrain. Neuroscience letters. vol 191. issue 1-2. 1995-09-29. PMID:7659275. |
in situ hybridization showed that the signals of th mrna were localized to the dopaminergic perikarya in the midbrain and were reduced in map-treated animals compared to the controls. |
1995-09-29 |
2023-08-12 |
rat |
| D Casper, M Blu. Epidermal growth factor and basic fibroblast growth factor protect dopaminergic neurons from glutamate toxicity in culture. Journal of neurochemistry. vol 65. issue 3. 1995-09-18. PMID:7643081. |
in this report we characterize the toxicity of the excitatory amino acid l-glutamate with respect to dopaminergic neurons cultured from embryonic rat mesencephalon. |
1995-09-18 |
2023-08-12 |
rat |
| K E Bowenkamp, A F Hoffman, G A Gerhardt, M A Henry, P T Biddle, B J Hoffer, A C Granhol. Glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons. The Journal of comparative neurology. vol 355. issue 4. 1995-09-14. PMID:7636027. |
glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons. |
1995-09-14 |
2023-08-12 |
rat |
| K E Bowenkamp, A F Hoffman, G A Gerhardt, M A Henry, P T Biddle, B J Hoffer, A C Granhol. Glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons. The Journal of comparative neurology. vol 355. issue 4. 1995-09-14. PMID:7636027. |
in order to determine if there is a positive effect of gdnf on injured adult midbrain dopaminergic neurons in situ, we have carried out experiments in which a single dose of gdnf was injected into the substantia nigra following a unilateral lesion of the nigrostriatal system. |
1995-09-14 |
2023-08-12 |
rat |