| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fatuel Tecuapetla, Jyoti C Patel, Harry Xenias, Daniel English, Ibrahim Tadros, Fulva Shah, Joshua Berlin, Karl Deisseroth, Margaret E Rice, James M Tepper, Tibor Koo. Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 20. 2010-06-04. PMID:20484653. |
recent evidence suggests the intriguing possibility that midbrain dopaminergic (daergic) neurons may use fast glutamatergic transmission to communicate with their postsynaptic targets. |
2010-06-04 |
2023-08-12 |
mouse |
| Emrah Düzel, Nico Bunzeck, Marc Guitart-Masip, Sandra Düze. NOvelty-related motivation of anticipation and exploration by dopamine (NOMAD): implications for healthy aging. Neuroscience and biobehavioral reviews. vol 34. issue 5. 2010-06-02. PMID:19715723. |
studies in humans and animals show that dopaminergic neuromodulation originating from the substantia nigra/ventral tegmental area (sn/vta) of the midbrain enhances hippocampal synaptic plasticity for novel events and has a motivationally energizing effect on actions through striatal mechanisms. |
2010-06-02 |
2023-08-12 |
Not clear |
| Masami Ishido, Junko Suzuk. Inhibition by rotenone of mesencephalic neural stem-cell migration in a neurosphere assay in vitro. Toxicology in vitro : an international journal published in association with BIBRA. vol 24. issue 2. 2010-06-02. PMID:19900533. |
here we examined the in vitro effects of the environmental dopaminergic toxin rotenone on neural stem cells, derived from the rat e16 mesencephalon. |
2010-06-02 |
2023-08-12 |
rat |
| Thomas E Hazy, Michael J Frank, Randall C O'Reill. Neural mechanisms of acquired phasic dopamine responses in learning. Neuroscience and biobehavioral reviews. vol 34. issue 5. 2010-06-02. PMID:19944716. |
what biological mechanisms underlie the reward-predictive firing properties of midbrain dopaminergic neurons, and how do they relate to the complex constellation of empirical findings understood as pavlovian and instrumental conditioning? |
2010-06-02 |
2023-08-12 |
Not clear |
| Henry W Chase, Luke Clar. Gambling severity predicts midbrain response to near-miss outcomes. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 18. 2010-06-02. PMID:20445043. |
gambling severity, measured with the south oaks gambling screen, predicted a greater response in the dopaminergic midbrain to near-miss outcomes. |
2010-06-02 |
2023-08-12 |
human |
| Yuichi Ono, Tomoya Nakatani, Yasuko Minaki, Minoru Kuma. The basic helix-loop-helix transcription factor Nato3 controls neurogenic activity in mesencephalic floor plate cells. Development (Cambridge, England). vol 137. issue 11. 2010-06-02. PMID:20460368. |
as a consequence, the number of midbrain dopaminergic neurons generated was decreased in mutants. |
2010-06-02 |
2023-08-12 |
mouse |
| Chin-Yu Lu, Pei-Lu Yi, Chon-Haw Tsai, Chiung-Hsiang Cheng, Han-Han Chang, Yi-Tse Hsiao, Fang-Chia Chan. TNF-NF-kappaB signaling mediates excessive somnolence in hemiparkinsonian rats. Behavioural brain research. vol 208. issue 2. 2010-05-25. PMID:20043954. |
our results indicated that microglial activation caused the loss of dopaminergic neurons in the substantia nigra, and the expression of tnf-alpha, but not il-1beta, increased in the midbrain and hypothalamus in mg-132-induced hemiparkinsonian rats. |
2010-05-25 |
2023-08-12 |
rat |
| Lei Phillip Wang, Fei Li, Xiaoming Shen, Joe Z Tsie. Conditional knockout of NMDA receptors in dopamine neurons prevents nicotine-conditioned place preference. PloS one. vol 5. issue 1. 2010-05-20. PMID:20062537. |
it is known that nicotine triggers tobacco addiction by activating nicotine acetylcholine receptors (nachrs) in the midbrain dopaminergic reward system, primarily via the ventral tegmental area. |
2010-05-20 |
2023-08-12 |
mouse |
| Vanesa Sanchez-Guajardo, Fabia Febbraro, Deniz Kirik, Marina Romero-Ramo. Microglia acquire distinct activation profiles depending on the degree of alpha-synuclein neuropathology in a rAAV based model of Parkinson's disease. PloS one. vol 5. issue 1. 2010-05-20. PMID:20098715. |
to investigate this we used a recombinant viral vector to express human alpha-syn in rat midbrain at levels that induced neuronal pathology either in the absence or the presence of dopaminergic cell death, thereby mimicking early or late stages of the disease. |
2010-05-20 |
2023-08-12 |
human |
| Claudio Da Cunha, Evellyn Claudia Wietzikoski, Mariza Bortolanza, Patricia Andréia Dombrowski, Lucélia Mendes dos Santos, Suelen Lúcio Boschen, Edmar Miyoshi, Maria Aparecida Barbato Frazão Vital, Roseli Boerngen-Lacerda, Roberto Andreatin. Non-motor function of the midbrain dopaminergic neurons. Journal of neural transmission. Supplementum. issue 73. 2010-05-14. PMID:20411775. |
non-motor function of the midbrain dopaminergic neurons. |
2010-05-14 |
2023-08-12 |
human |
| Jonathan P Roiser, Klaas E Stephan, Hanneke E M den Ouden, Karl J Friston, Eileen M Joyc. Adaptive and aberrant reward prediction signals in the human brain. NeuroImage. vol 50. issue 2. 2010-05-11. PMID:19969090. |
as expected, cues associated with high relative to low reward probabilities elicited robust hemodynamic responses in a network of structures previously implicated in motivational salience; the midbrain, in the vicinity of the ventral tegmental area, and regions targeted by its dopaminergic projections, i.e. |
2010-05-11 |
2023-08-12 |
human |
| Vinay Parikh, Jinzhao Ji, Michael W Decker, Martin Sarte. Prefrontal beta2 subunit-containing and alpha7 nicotinic acetylcholine receptors differentially control glutamatergic and cholinergic signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 9. 2010-05-05. PMID:20203212. |
transients were recorded in mice lacking beta2 or alpha7 nachrs and in rats after removal of thalamic glutamatergic or midbrain dopaminergic inputs to prefrontal cortex. |
2010-05-05 |
2023-08-12 |
mouse |
| Lubica Kubikova, Lubor Kostá. Dopaminergic system in birdsong learning and maintenance. Journal of chemical neuroanatomy. vol 39. issue 2. 2010-05-04. PMID:19900537. |
several song and auditory nuclei are innervated by midbrain dopaminergic fibers and contain neurons with various dopamine receptors. |
2010-05-04 |
2023-08-12 |
Not clear |
| Lubica Kubikova, Lubor Kostá. Dopaminergic system in birdsong learning and maintenance. Journal of chemical neuroanatomy. vol 39. issue 2. 2010-05-04. PMID:19900537. |
during sexually motivated singing, activity of midbrain dopaminergic neurons in the ventral tegmental area and dopamine release in the striatal area x, involved in song learning and maintenance, are higher. |
2010-05-04 |
2023-08-12 |
Not clear |
| D Bajic, K G Common. Acute noxious stimulation modifies morphine effect in serotonergic but not dopaminergic midbrain areas. Neuroscience. vol 166. issue 2. 2010-05-03. PMID:20026253. |
acute noxious stimulation modifies morphine effect in serotonergic but not dopaminergic midbrain areas. |
2010-05-03 |
2023-08-12 |
rat |
| Chong Shi, Yu-xin Zhang, Zuo-feng Zhan. [Effect of phosphorylated-ERK1/2 on inducible nitric oxide synthase expression in the substantia nigra of mice with MPTP-induced Parkinson disease]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 29. issue 1. 2010-04-29. PMID:19218114. |
to investigate the effect of phosphorylated-erk1/2 (p-erk1/2) on inducible nitric oxide synthase (inos) expression in the substantia nigra (sn) of a mouse model of parkinson's disease (pd), and explore the possible mechanism of dopaminergic (da) neuron loss in the sn of the midbrain in pd. |
2010-04-29 |
2023-08-12 |
mouse |
| Kyle M Sousa, J Carlos Villaescusa, Lukas Cajanek, Jennifer K Ondr, Goncalo Castelo-Branco, Wytske Hofstra, Vitezslav Bryja, Carina Palmberg, Tomas Bergman, Brandon Wainwright, Richard A Lang, Ernest Arena. Wnt2 regulates progenitor proliferation in the developing ventral midbrain. The Journal of biological chemistry. vol 285. issue 10. 2010-04-29. PMID:20018874. |
moreover, purified wnt2 increases progenitor proliferation, and the number of dopaminergic neurons in ventral midbrain precursor cultures. |
2010-04-29 |
2023-08-12 |
mouse |
| Kyle M Sousa, J Carlos Villaescusa, Lukas Cajanek, Jennifer K Ondr, Goncalo Castelo-Branco, Wytske Hofstra, Vitezslav Bryja, Carina Palmberg, Tomas Bergman, Brandon Wainwright, Richard A Lang, Ernest Arena. Wnt2 regulates progenitor proliferation in the developing ventral midbrain. The Journal of biological chemistry. vol 285. issue 10. 2010-04-29. PMID:20018874. |
in agreement with these findings, analysis of the ventral midbrain of developing wnt2-null mice revealed a decrease in progenitor proliferation and neurogenesis that lead to a decrease in the number of postmitotic precursors and dopaminergic neurons. |
2010-04-29 |
2023-08-12 |
mouse |
| David J Brook. Imaging approaches to Parkinson disease. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 51. issue 4. 2010-04-19. PMID:20351351. |
demonstrating midbrain structural abnormalities with transcranial sonography or diffusion-weighted mri or showing striatal dopamine terminal dysfunction with pet or spect supports the diagnosis and rationalizes the use of dopaminergic medications. |
2010-04-19 |
2023-08-12 |
Not clear |
| Sheng Deng, Hao Deng, Weidong Le, Hongbo Xu, Huarong Yang, Xiong Deng, Hongwei Lv, Wenjie Xie, Shaihong Zhu, Joseph Jankovi. Genetic analysis of the NEUROG2 gene in patients with Parkinson's disease. Neuroscience letters. vol 468. issue 3. 2010-04-06. PMID:19879328. |
the proneural protein neurogenin 2 (neurog2) is a transcription factor of importance for the differentiation and survival of midbrain dopaminergic neurons. |
2010-04-06 |
2023-08-12 |
Not clear |