| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Qing Zhang, Su-Chun Zhan. Differentiation of neural precursors and dopaminergic neurons from human embryonic stem cells. Methods in molecular biology (Clifton, N.J.). vol 584. 2010-02-05. PMID:19907987. |
identification of the primitive neuroepithelial cells permits efficient patterning of region-specific progenitors and neuronal subtypes such as midbrain dopaminergic neurons. |
2010-02-05 |
2023-08-12 |
mouse |
| Oscar Diaz-Ruiz, Agustin Zapata, Lufei Shan, YaJun Zhang, Andreas C Tomac, Nasir Malik, Fidel de la Cruz, Cristina M Bäckma. Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons. PloS one. vol 4. issue 9. 2010-02-01. PMID:19750226. |
the resulting mutant mice showed neuronal hypertrophy, and an increased number of dopaminergic neurons and fibers in the ventral mesencephalon. |
2010-02-01 |
2023-08-12 |
mouse |
| Rachel Hammond, Sandra Blaess, Asa Abeliovic. Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons. PloS one. vol 4. issue 9. 2010-02-01. PMID:19774071. |
sonic hedgehog is a chemoattractant for midbrain dopaminergic axons. |
2010-02-01 |
2023-08-12 |
mouse |
| Rachel Hammond, Sandra Blaess, Asa Abeliovic. Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons. PloS one. vol 4. issue 9. 2010-02-01. PMID:19774071. |
midbrain dopaminergic axons project from the substantia nigra (sn) and the ventral tegmental area (vta) to rostral target tissues, including the striatum, pallidum, and hypothalamus. |
2010-02-01 |
2023-08-12 |
mouse |
| Rachel Hammond, Sandra Blaess, Asa Abeliovic. Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons. PloS one. vol 4. issue 9. 2010-02-01. PMID:19774071. |
furthermore, in midbrain explants, dopaminergic projections are attracted to a shh source. |
2010-02-01 |
2023-08-12 |
mouse |
| Anne-Marie Duchemin, Hailing Zhang, Norton H Neff, Maria Hadjiconstantino. Increased expression of VMAT2 in dopaminergic neurons during nicotine withdrawal. Neuroscience letters. vol 467. issue 2. 2010-02-01. PMID:19835933. |
vmat2 up-regulation might be a compensatory mechanism to restore and maintain synaptic transmission in dopaminergic midbrain neurons during nicotine withdrawal. |
2010-02-01 |
2023-08-12 |
mouse |
| Carlotta E Duncan, Peter R Schofield, Cynthia Shannon Weicker. K(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. Brain research. vol 1304. 2010-01-28. PMID:19781530. |
k(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. |
2010-01-28 |
2023-08-12 |
mouse |
| Carlotta E Duncan, Peter R Schofield, Cynthia Shannon Weicker. K(v) channel interacting protein 3 expression and regulation by haloperidol in midbrain dopaminergic neurons. Brain research. vol 1304. 2010-01-28. PMID:19781530. |
this study, for the first time, also localized kchip3 protein in the cell bodies and processes of dopaminergic neurons in the midbrain. |
2010-01-28 |
2023-08-12 |
mouse |
| Christopher A Deister, Mark A Teagarden, Charles J Wilson, Carlos A Paladin. An intrinsic neuronal oscillator underlies dopaminergic neuron bursting. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016105. |
dopaminergic neurons of the ventral midbrain fire high-frequency bursts when animals are presented with unexpected rewards, or stimuli that predict reward. |
2010-01-26 |
2023-08-12 |
Not clear |
| Howard J Federof. Nur(R1)turing a notion on the etiopathogenesis of Parkinson's disease. Neurotoxicity research. vol 16. issue 3. 2010-01-25. PMID:19526279. |
the canonical histopathological feature of parkinson's disease (pd) is the loss of dopaminergic neurons in the ventral midbrain. |
2010-01-25 |
2023-08-12 |
Not clear |
| Dardo Tomasi, Gene-Jack Wang, Ruiliang Wang, Walter Backus, Allan Geliebter, Frank Telang, Millar C Jayne, Christopher Wong, Joanna S Fowler, Nora D Volko. Association of body mass and brain activation during gastric distention: implications for obesity. PloS one. vol 4. issue 8. 2010-01-19. PMID:19718256. |
since obese subjects have dopaminergic deficits that correlate negatively with bmi and the amygdala is innervated by dopamine neurons, we hypothesized that bmi would correlate negatively with activation not just in the amygdala but also in other dopaminergic brain regions (midbrain and hypothalamus). |
2010-01-19 |
2023-08-12 |
human |
| Francesco Roselli, Nicola M Pisciotta, Robert Perneczky, Michele Pennelli, Maria S Aniello, Maria F De Caro, Ermanno Ferrannini, Bruno Tartaglione, Giovanni Defazio, Giuseppe Rubini, Paolo Livre. Severity of neuropsychiatric symptoms and dopamine transporter levels in dementia with Lewy bodies: a 123I-FP-CIT SPECT study. Movement disorders : official journal of the Movement Disorder Society. vol 24. issue 14. 2010-01-12. PMID:19705471. |
dopamine transporter (dat) imaging with (123)i-labeled ligand n-delta-(fluoropropyl)-2 beta-carbomethoxy-3beta-(4-iodophenyl)tropene ((123)i-fp-cit), which reliably measures midbrain dopaminergic dysfunction, has provided important evidence on the neurobiological substrate of some of these symptoms including apathy and depression. |
2010-01-12 |
2023-08-12 |
Not clear |
| Victoria E Shaw, Sharon Spana, Keyoumars Ashkan, Alim-Louis Benabid, Jonathan Stone, Gary E Baker, John Mitrofani. Neuroprotection of midbrain dopaminergic cells in MPTP-treated mice after near-infrared light treatment. The Journal of comparative neurology. vol 518. issue 1. 2010-01-11. PMID:19882716. |
neuroprotection of midbrain dopaminergic cells in mptp-treated mice after near-infrared light treatment. |
2010-01-11 |
2023-08-12 |
mouse |
| Deepinder Kaur, Subramanian Rajagopalan, Julie K Anderse. Chronic expression of H-ferritin in dopaminergic midbrain neurons results in an age-related expansion of the labile iron pool and subsequent neurodegeneration: implications for Parkinson's disease. Brain research. vol 1297. 2010-01-08. PMID:19699718. |
chronic expression of h-ferritin in dopaminergic midbrain neurons results in an age-related expansion of the labile iron pool and subsequent neurodegeneration: implications for parkinson's disease. |
2010-01-08 |
2023-08-12 |
mouse |
| Milan Joksimovic, Angela Anderegg, Anil Roy, Laura Campochiaro, Beth Yun, Raja Kittappa, Ronald McKay, Rajeshwar Awatraman. Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 45. 2010-01-06. PMID:19850875. |
spatiotemporally separable shh domains in the midbrain define distinct dopaminergic progenitor pools. |
2010-01-06 |
2023-08-12 |
Not clear |
| J W Dickerson, A M Hemmerle, S Numan, K H Lundgren, K B Seroog. Decreased expression of ErbB4 and tyrosine hydroxylase mRNA and protein in the ventral midbrain of aged rats. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19505538. |
to determine if levels of the nrg receptor are maintained during aging in the dopaminergic ventral mesencephalon, expression of erbb4 mrna and protein was examined in young (3 months), middle-aged (18 months), and old (24-25 months) brown norway/fischer 344 f1 rats. |
2009-12-15 |
2023-08-12 |
rat |
| Paola Sacchetti, Kyle M Sousa, Anita C Hall, Isabel Liste, Knut R Steffensen, Spyridon Theofilopoulos, Clare L Parish, Carin Hazenberg, Lars Ahrlund Richter, Outti Hovatta, Jan-Ake Gustafsson, Ernest Arena. Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell stem cell. vol 5. issue 4. 2009-12-14. PMID:19796621. |
here, we examined the function of two nuclear receptors, liver x receptors (lxralpha and beta) and their ligands, oxysterols, as regulators of cell division, ventral midbrain (vm) neurogenesis, and dopaminergic (da) neuron development. |
2009-12-14 |
2023-08-12 |
mouse |
| Henry Lütcke, Holger Gevensleben, Björn Albrecht, Jens Frah. Brain networks involved in early versus late response anticipation and their relation to conflict processing. Journal of cognitive neuroscience. vol 21. issue 11. 2009-12-11. PMID:19016602. |
additionally, late anticipation was associated with increased activity in midbrain dopaminergic nuclei, very likely corresponding to the substantia nigra. |
2009-12-11 |
2023-08-12 |
human |
| Josephine B Hebsgaard, Jenny Nelander, Hanna Sabelström, Marie E Jönsson, Simon Stott, Malin Parma. Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. Glia. vol 57. issue 15. 2009-12-09. PMID:19330857. |
specification and differentiation of neural precursors into dopaminergic neurons within the ventral mesencephalon has been subject to much attention due to the implication of dopaminergic neurons in parkinson's disease and the perspective of generating sources of therapeutically active cells to be used for cell replacement therapy for the disease. |
2009-12-09 |
2023-08-12 |
human |
| Josephine B Hebsgaard, Jenny Nelander, Hanna Sabelström, Marie E Jönsson, Simon Stott, Malin Parma. Dopamine neuron precursors within the developing human mesencephalon show radial glial characteristics. Glia. vol 57. issue 15. 2009-12-09. PMID:19330857. |
within the mesencephalon, lmx1a is expressed in the dopaminergic neurons and their progenitors located in the ventricular zone of the floor plate region. |
2009-12-09 |
2023-08-12 |
human |