| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Blandini, J T Greenamyr. Prospects of glutamate antagonists in the therapy of Parkinson's disease. Fundamental & clinical pharmacology. vol 12. issue 1. 1998-05-06. PMID:9523179. |
degeneration of dopamine nigral neurons and striatal dopaminergic denervation cause a cascade of functional modifications in the activity of basal ganglia nuclei. |
1998-05-06 |
2023-08-12 |
Not clear |
| F Blandini, J T Greenamyr. Prospects of glutamate antagonists in the therapy of Parkinson's disease. Fundamental & clinical pharmacology. vol 12. issue 1. 1998-05-06. PMID:9523179. |
due to the close relationship that links dopaminergic and glutamatergic neurotransmission, glutamate is directly involved in the functional alterations of basal ganglia circuitry that lead to the development of parkinsonian motor symptoms. |
1998-05-06 |
2023-08-12 |
Not clear |
| K Kannari, T Maeda, M Matsunaga, T Sud. [Reduction of apomorphine-induced rotation in rats with additional destruction of the pedunculopontine nucleus contralateral to the unilateral nigrostriatal lesion]. No to shinkei = Brain and nerve. vol 50. issue 1. 1998-04-21. PMID:9493196. |
although ppn might not serve as an output route for the dopaminergic neurotransmission in the basal ganglia, ppn itself could rather induce some movement affecting the basal ganglia. |
1998-04-21 |
2023-08-12 |
rat |
| R T Pikieln. [Parkinson's disease: from pallidotomy to L-dopa and back to pallidotomy]. Medicina. vol 57. issue 1. 1998-04-07. PMID:9435379. |
the mptp epidemic in heroin addicts was responsible for obtaining an experimental model of ipd and became the starting point for a wealth of information concerning the physiopathology of basal ganglia circuitry, neurotransmitters and specific dopaminergic, gabaergic and glutamaergic receptor subtypes involved in motor control. |
1998-04-07 |
2023-08-12 |
Not clear |
| K R Müller-Vahl, H Kolbe, R Dengle. [Gilles de la Tourette syndrome. Effect of nicotine, alcohol and marihuana on clinical symptoms]. Der Nervenarzt. vol 68. issue 12. 1998-04-01. PMID:9465342. |
we suggest that marijuana influences an assumed interaction between cannabinoid and dopamine receptors and, by this, influences the dopaminergic processes in basal ganglia and motor activity. |
1998-04-01 |
2023-08-12 |
Not clear |
| T Müller, J Farahati, W Kuhn, E G Eising, H Przuntek, C Reiners, H H Coene. [123I]beta-CIT SPECT visualizes dopamine transporter loss in de novo parkinsonian patients. European neurology. vol 39. issue 1. 1998-03-26. PMID:9476723. |
parkinson's disease (pd) is characterized by degeneration of dopaminergic neurons in the basal ganglia, which may be visualized by single photon emission computed tomography (spect) in combination with the cocaine analog methyl-3-beta-(4-beta[123i]iodophenyl)tropane-2beta-carboxylate ([123i]beta-cit). |
1998-03-26 |
2023-08-12 |
human |
| A Stefani, P Stanzione, A Bassi, P Mazzone, T Vangelista, G Bernard. Effects of increasing doses of apomorphine during stereotaxic neurosurgery in Parkinson's disease: clinical score and internal globus pallidus activity. Short communication. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 8-9. 1998-02-26. PMID:9451721. |
these finding suggest that the reduction of internal pallidus excitability is one of the mechanisms underlying the efficacy of dopaminergic therapy, but also that changes in other basal ganglia stations are likely to be involved in dyskinesias. |
1998-02-26 |
2023-08-12 |
Not clear |
| Y Tashiro, J M Drake, S Chakrabortty, T Hattor. Functional injury of cholinergic, GABAergic and dopaminergic systems in the basal ganglia of adult rat with kaolin-induced hydrocephalus. Brain research. vol 770. issue 1-2. 1998-01-21. PMID:9372201. |
the present study was designed to investigate possible functional injury of cholinergic, gabaergic and dopaminergic systems in the basal ganglia immunohistochemically in a model of kaolin-induced hydrocephalus. |
1998-01-21 |
2023-08-12 |
rat |
| T Rammsayer, W Classe. Impaired temporal discrimination in Parkinson's disease: temporal processing of brief durations as an indicator of degeneration of dopaminergic neurons in the basal ganglia. The International journal of neuroscience. vol 91. issue 1-2. 1997-12-29. PMID:9394214. |
impaired temporal discrimination in parkinson's disease: temporal processing of brief durations as an indicator of degeneration of dopaminergic neurons in the basal ganglia. |
1997-12-29 |
2023-08-12 |
Not clear |
| T Rammsayer, W Classe. Impaired temporal discrimination in Parkinson's disease: temporal processing of brief durations as an indicator of degeneration of dopaminergic neurons in the basal ganglia. The International journal of neuroscience. vol 91. issue 1-2. 1997-12-29. PMID:9394214. |
recent findings suggest that temporal processing of brief durations is a function of dopaminergic neurotransmission in the basal ganglia. |
1997-12-29 |
2023-08-12 |
Not clear |
| T Rammsayer, W Classe. Impaired temporal discrimination in Parkinson's disease: temporal processing of brief durations as an indicator of degeneration of dopaminergic neurons in the basal ganglia. The International journal of neuroscience. vol 91. issue 1-2. 1997-12-29. PMID:9394214. |
the overall pattern of results suggests that deficits in temporal information processing observed in pd patients may represent a trait marker of vulnerability to decreasing levels of dopaminergic activity in the basal ganglia rather than a state-dependent indicator of the acute clinical symptomatology. |
1997-12-29 |
2023-08-12 |
Not clear |
| E Ongini, M Adami, C Ferri, R Bertorell. Adenosine A2A receptors and neuroprotection. Annals of the New York Academy of Sciences. vol 825. 1997-12-09. PMID:9369973. |
their activity is attributed to the close anatomical and functional links between a2a receptors and dopaminergic pathways in the basal ganglia. |
1997-12-09 |
2023-08-12 |
Not clear |
| T H Rammsaye. Effects of body core temperature and brain dopamine activity on timing processes in humans. Biological psychology. vol 46. issue 2. 1997-12-02. PMID:9288412. |
for temporal discrimination of intervals in the range of seconds, a significant interaction between ambient temperature and haloperidol could be established (p < 0.05) indicating that haloperidol caused a significant performance decrement only in subjects exposed to an ambient temperature of 28 degrees c but not in those exposed to 52 degrees c. the overall pattern of results suggests that temporal processing of intervals in the range of milliseconds can be considered a function of dopaminergic activity in the basal ganglia while temporal processing of longer intervals appears to be cognitively mediated. |
1997-12-02 |
2023-08-12 |
human |
| J F Marshall, D N Ruskin, G J LaHost. Dopaminergic regulation of immediate early gene expression in the basal ganglia. Advances in pharmacology (San Diego, Calif.). vol 42. 1997-11-25. PMID:9327990. |
dopaminergic regulation of immediate early gene expression in the basal ganglia. |
1997-11-25 |
2023-08-12 |
Not clear |
| J N Joyce, S G Goldsmith, E V Gurevic. Limbic circuits and monoamine receptors: dissecting the effects of antipsychotics from disease processes. Journal of psychiatric research. vol 31. issue 2. 1997-10-23. PMID:9278186. |
however, dopaminergic systems in the temporal lobe have historically been thought to be underdeveloped compared to that in the basal ganglia and unlikely to be the target of antipsychotics. |
1997-10-23 |
2023-08-12 |
Not clear |
| C A Ingham, S H Hood, M J Mijnster, R A Baldock, G W Arbuthnot. Plasticity of striatopallidal terminals following unilateral lesion of the dopaminergic nigrostriatal pathway: a morphological study. Experimental brain research. vol 116. issue 1. 1997-10-23. PMID:9305813. |
in parkinson's disease the dopaminergic nigrostriatal pathway degenerates, resulting in an imbalance in activity of two pathways of information flow through the basal ganglia. |
1997-10-23 |
2023-08-12 |
Not clear |
| F X Castellano. Toward a pathophysiology of attention-deficit/hyperactivity disorder. Clinical pediatrics. vol 36. issue 7. 1997-08-21. PMID:9241475. |
anatomic neuroimaging studies suggest that the relevant regulatory circuits include the prefrontal cortex and the basal ganglia, which are modulated by dopaminergic innervation from the midbrain and by stimulant medications. |
1997-08-21 |
2023-08-12 |
Not clear |
| E Asa. Ultrastructural features of tyrosine-hydroxylase-immunoreactive afferents and their targets in the rat amygdala. Cell and tissue research. vol 288. issue 3. 1997-08-15. PMID:9134859. |
the results suggest that tyrosine-hydroxylase-immunoreactive, predominantly dopaminergic amygdaloid afferent fibres preferentially modulate the effect of extrinsic inputs into neurons of the central and basal nuclei, while a nonselective regulation is exerted upon the output of paracapsular intercalated neurons. |
1997-08-15 |
2023-08-12 |
rat |
| F Heinemann, H J Assion, G Lau. [Neuroleptic malignant syndrome from treatment with antidepressives]. Fortschritte der Neurologie-Psychiatrie. vol 65. issue 5. 1997-07-31. PMID:9235312. |
a dopaminergic transmission block in the basal ganglia and the hypothalamus is thought to be the pathophysiological mechanism of nms. |
1997-07-31 |
2023-08-12 |
Not clear |
| M D Lindner, M A Plone, J M Francis, T J Blaney, J D Salamone, D F Emeric. Rats with partial striatal dopamine depletions exhibit robust and long-lasting behavioral deficits in a simple fixed-ratio bar-pressing task. Behavioural brain research. vol 86. issue 1. 1997-07-15. PMID:9105579. |
it is widely accepted that enduring parkinsonian symptoms are only evident if there are few remaining dopaminergic neurons in the substantia nigra and dopamine levels in the basal ganglia are very low [26,41]. |
1997-07-15 |
2023-08-12 |
rat |