| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martin Reznitsky, Per Plenge, Anders Hay-Schmid. Serotonergic projections from the raphe nuclei to the subthalamic nucleus; a retrograde- and anterograde neuronal tracing study. Neuroscience letters. vol 612. 2016-06-28. PMID:26683905. |
several studies in recent years have shown that serotonin (5-ht) might have a therapeutic role in the most prevalent basal ganglia (bg) movement disorder, parkinson's disease (pd), but, because of the depletion of dopaminergic input to the bg, l-dopa has been the main treatment for pd patients. |
2016-06-28 |
2023-08-13 |
rat |
| Sagar Modi, Geetanjali Arora, Chandra Shekhar Bal, Vishnubhatla Sreenivas, Suparna Kailash, Rajesh Sagar, Ravinder Goswam. Effect of basal ganglia calcification on its glucose metabolism and dopaminergic function in idiopathic hypoparathyroidism. Clinical endocrinology. vol 83. issue 4. 2016-06-20. PMID:25366923. |
effect of basal ganglia calcification on its glucose metabolism and dopaminergic function in idiopathic hypoparathyroidism. |
2016-06-20 |
2023-08-13 |
Not clear |
| Jia Liu, Chun-li Duan, Hui Yan. [Research Progress of Pathogenesis and Treatment of Parkinsons Disease]. Sheng li ke xue jin zhan [Progress in physiology]. vol 46. issue 3. 2016-06-10. PMID:26521479. |
the most prominent symptom of pd is the impairment of motor behavior due to the loss of dopaminergic neurons and the consequent loss of the dopamine signaling in the basal ganglia. |
2016-06-10 |
2023-08-13 |
Not clear |
| Ferdinando Franco Calabria, Eros Calabria, Vincenzo Gangemi, Giuseppe Lucio Cascin. Current status and future challenges of brain imaging with (18)F-DOPA PET for movement disorders. Hellenic journal of nuclear medicine. vol 19. issue 1. 2016-06-07. PMID:26929938. |
parkinson's disease (pd) is a neurodegenerative disorder (nd) due to progressive loss of dopaminergic neurons in the basal ganglia. |
2016-06-07 |
2023-08-13 |
Not clear |
| Matteo Bologna, Antonio Suppa, Antonella Conte, Anna Latorre, John C Rothwell, Alfredo Berardell. Are studies of motor cortex plasticity relevant in human patients with Parkinson's disease? Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 127. issue 1. 2016-05-27. PMID:25792075. |
a number of studies have reported abnormal responses to several different conditioning protocols, but their relationship to altered basal ganglia output and dopaminergic loss is still not entirely clear. |
2016-05-27 |
2023-08-13 |
human |
| Elisa Straulino, Tomaso Scaravilli, Umberto Castiell. Social intentions in Parkinson's disease patients: A kinematic study. Cortex; a journal devoted to the study of the nervous system and behavior. vol 70. 2016-05-17. PMID:25804938. |
the dopaminergic input to the basal ganglia (bg) thought to integrate social cues during the planning and execution of voluntary movements remains, however, largely unexplored. |
2016-05-17 |
2023-08-13 |
human |
| Kaylena A Ehgoetz Martens, Colin G Ellard, Quincy J Almeid. Anxiety-provoked gait changes are selectively dopa-responsive in Parkinson's disease. The European journal of neuroscience. vol 42. issue 4. 2016-05-06. PMID:25899750. |
improvements to gait during anxious walking might be a result of dopaminergic medication acting in two ways: (i) improving the basal ganglia's capacity to process information and (ii) reducing the load from anxiety and subsequently making more resources available to effectively process other competing inputs. |
2016-05-06 |
2023-08-13 |
human |
| Marc Deffains, Hagai Bergma. Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 8. 2016-05-06. PMID:26095280. |
basal ganglia disorders are often associated with an imbalance between the midbrain dopaminergic and striatal cholinergic systems. |
2016-05-06 |
2023-08-13 |
Not clear |
| Pragathi Priyadharsini Balasubramani, V Srinivasa Chakravarthy, Manal Ali, Balaraman Ravindran, Ahmed A Moustaf. Identifying the Basal Ganglia network model markers for medication-induced impulsivity in Parkinson's disease patients. PloS one. vol 10. issue 6. 2016-05-02. PMID:26042675. |
a neural network model of the basal ganglia (bg) that has the capacity to predict the dysfunction of both the dopaminergic (da) and the serotonergic (5ht) neuromodulator systems was developed and used to facilitate the interpretation of experimental results. |
2016-05-02 |
2023-08-13 |
human |
| Satoshi Ikemoto, Chen Yang, Aaron Ta. Basal ganglia circuit loops, dopamine and motivation: A review and enquiry. Behavioural brain research. vol 290. 2016-04-04. PMID:25907747. |
the other concerns circuit loops involving the cerebral cortex, basal ganglia, thalamus, epithalamus, and midbrain through which dopaminergic activity alters approach motivation. |
2016-04-04 |
2023-08-13 |
Not clear |
| J Arbizu, M R Luquin, J Abella, R de la Fuente-Fernández, R Fernandez-Torrón, D García-Solís, P Garrastachu, J M Jiménez-Hoyuela, M Llaneza, F Lomeña, C Lorenzo-Bosquet, M J Martí, J C Martinez-Castrillo, P Mir, M Mitjavila, J Ruiz-Martínez, L Vel. [Functional neuroimaging in the diagnosis of patients with Parkinsonism: Update and recommendations for clinical use]. Revista espanola de medicina nuclear e imagen molecular. vol 33. issue 4. 2016-03-31. PMID:24731551. |
however, the wide range of radiotracers designed to assess the involvement of different pathways in the neurodegenerative process underlying parkinsonian syndromes (dopaminergic nigrostriatal pathway integrity, basal ganglia and cortical neuronal activity, myocardial sympathetic innervation), and the different neuroimaging techniques currently available (scintigraphy, spect and pet), have generated some controversy concerning the best neuroimaging test that should be indicated for the differential diagnosis of parkinsonism. |
2016-03-31 |
2023-08-13 |
Not clear |
| Maria Vadalà, Annamaria Vallelunga, Lucia Palmieri, Beniamino Palmieri, Julio Cesar Morales-Medina, Tommaso Iannitt. Mechanisms and therapeutic applications of electromagnetic therapy in Parkinson's disease. Behavioral and brain functions : BBF. vol 11. 2016-03-30. PMID:26347217. |
parkinson's disease is a neurodegenerative pathology caused by abnormal degeneration of dopaminergic neurons in the ventral tegmental area and substantia nigra pars compacta in the midbrain resulting in damage to the basal ganglia. |
2016-03-30 |
2023-08-13 |
Not clear |
| Collin J Anderson, Daylan T Sheppard, Rachel Huynh, Daria Nesterovich Anderson, Christian A Polar, Alan D Dorva. Subthalamic deep brain stimulation reduces pathological information transmission to the thalamus in a rat model of parkinsonism. Frontiers in neural circuits. vol 9. 2016-02-24. PMID:26217192. |
the degeneration of dopaminergic neurons in the substantia nigra pars compacta leads to parkinsonian motor symptoms via changes in electrophysiological activity throughout the basal ganglia. |
2016-02-24 |
2023-08-13 |
rat |
| M Zucconi, M Manconi, L Ferini Stramb. Aetiopathogenesis of restless legs syndrome. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 28 Suppl 1. 2016-02-23. PMID:17235431. |
different aspects of rls physiopathogenesis are discussed: the genetic components indicating different chromosomes are responsible for the heterogeneity in the phenotypic expression of the familial forms of rls; the neurophysiologic data showing the hyperexcitability of the cortico-motor efferents at supraspinal level, with spinal cord involvement leading to a definition of rls as a syndrome of somatosensory misperception, disturbed gain regulation and/or a shifted threshold; the paucity of neuroimaging data, which do not definitively clarify the eventual dopaminergic dysfunction in rls patients, at least at the basal ganglia level; an illustration of the iposideremic hypothesis starting from the therapeutic effect of iron, although not for all patients, and based on some neurophysiologic and neuropathologic results both in humans and animal models; and finally the role of the opioid system, suggesting an imbalance of dopamine-opiate system inputs to brain regions involved in motor responses and pain perception, and representing an aberrant behavioural response to sensory inputs. |
2016-02-23 |
2023-08-12 |
Not clear |
| Raghav Gupta, Christopher Kim, Nitin Agarwal, Bryan Lieber, Edward A Monac. Understanding the Influence of Parkinson Disease on Adolf Hitler's Decision-Making during World War II. World neurosurgery. vol 84. issue 5. 2016-02-16. PMID:26093359. |
parkinson disease (pd) is a common neurodegenerative disorder characterized by the presence of lewy bodies and a reduction in the number of dopaminergic neurons in the substantia nigra of the basal ganglia. |
2016-02-16 |
2023-08-13 |
Not clear |
| Anne-Marike Schiffer, Florian Waszak, Nick Yeun. The role of prediction and outcomes in adaptive cognitive control. Journal of physiology, Paris. vol 109. issue 1-3. 2016-02-08. PMID:25698177. |
the model lastly envisages a role for hierarchical projections from the striatum to dopaminergic midbrain areas that enable more rostral frontal areas to bias the selection of inputs from more posterior frontal areas via their respective representations in the basal ganglia. |
2016-02-08 |
2023-08-13 |
human |
| Cheng-Kai Huang, Jay Wu, Kai-Yuan Cheng, Lung-Kwang Pa. Optimization of imaging parameters for SPECT scans of [99mTc]TRODAT-1 using Taguchi analysis. PloS one. vol 10. issue 3. 2016-02-04. PMID:25790100. |
parkinson's disease (pd) is a neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the basal ganglia. |
2016-02-04 |
2023-08-13 |
human |
| T C Booth, M Nathan, A D Waldman, A-M Quigley, A H Schapira, J Buscomb. The role of functional dopamine-transporter SPECT imaging in parkinsonian syndromes, part 1. AJNR. American journal of neuroradiology. vol 36. issue 2. 2016-01-04. PMID:24904053. |
the common pathologic pathway of these diseases, collectively described as parkinsonian syndromes, such as parkinson disease, multiple system atrophy, progressive supranuclear palsy, corticobasal degeneration, and dementia with lewy bodies, is degeneration of the presynaptic dopaminergic pathways in the basal ganglia. |
2016-01-04 |
2023-08-13 |
Not clear |
| Flavia Niccolini, Thomas Foltynie, Tiago Reis Marques, Nils Muhlert, Andri C Tziortzi, Graham E Searle, Sridhar Natesan, Shitij Kapur, Eugenii A Rabiner, Roger N Gunn, Paola Piccini, Marios Politi. Loss of phosphodiesterase 10A expression is associated with progression and severity in Parkinson's disease. Brain : a journal of neurology. vol 138. issue Pt 10. 2015-12-28. PMID:26210536. |
phosphodiesterase 10a (pde10a) is a basal ganglia expressed dual substrate enzyme, which regulates camp and cgmp signalling cascades, thus having a key role in the regulation of dopaminergic signalling in striatal pathways, and in promoting neuronal survival. |
2015-12-28 |
2023-08-13 |
Not clear |
| Emma Arvidsson, Thomas Viereckel, Sanja Mikulovic, Åsa Wallén-Mackenzi. Age- and sex-dependence of dopamine release and capacity for recovery identified in the dorsal striatum of C57/Bl6J mice. PloS one. vol 9. issue 6. 2015-12-14. PMID:24925086. |
the dorsal striatum is the main input structure of the basal ganglia and the major target area of dopaminergic projections originating in the substantia nigra pars compacta. |
2015-12-14 |
2023-08-13 |
mouse |