| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan C Jurado-Coronel, Marco Ávila-Rodriguez, Valentina Echeverria, Oscar Alejandro Hidalgo, Janneth Gonzalez, Gjumrakch Aliev, George E Barret. Implication of Green Tea as a Possible Therapeutic Approach for Parkinson Disease. CNS & neurological disorders drug targets. vol 15. issue 3. 2016-12-19. PMID:26831259. |
parkinson's disease (pd) is the second more common neurodegenerative disorders, after alzheimer's disease and is characterized by degeneration of dopaminergic neurons in the pars compact of the substantia nigra of the basal ganglia. |
2016-12-19 |
2023-08-13 |
Not clear |
| Seishu Nakagawa, Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Yuka Kotozaki, Takamitsu Shinada, Tsukasa Maruyama, Atsushi Sekiguchi, Kunio Iizuka, Ryoichi Yokoyama, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Daniele Magistro, Kohei Sakaki, Hyeonjeong Jeong, Yukako Sasaki, Ryuta Kawashim. Basal ganglia correlates of fatigue in young adults. Scientific reports. vol 6. 2016-12-19. PMID:26893077. |
a plausible mechanism of fatigue may involve abnormal function of the motor system, as well as areas of the dopaminergic system in the basal ganglia that are associated with motivation and reward. |
2016-12-19 |
2023-08-13 |
human |
| Rhanor Gillette, Jeffrey W Brow. The Sea Slug, Pleurobranchaea californica: A Signpost Species in the Evolution of Complex Nervous Systems and Behavior. Integrative and comparative biology. vol 55. issue 6. 2016-12-13. PMID:26163678. |
they suggest (1) an origin of olfactory bulb and pallium from head-region pns; (2) modularization of an ancestral feeding network into discrete but interacting executive modules for incentive comparison and decision (basal ganglia), and homeostatic functions (hypothalamus); (3) modification of a multifunctional premotor network for turns and locomotion, and its downstream targets for mid-brain and hind-brain motor areas and spinal cpgs; (4) condensation of a distributed serotonergic network for arousal into the raphe nuclei, with superimposed control by a peptidergic hypothalamic network mediating appetite and arousal; (5) centralization and condensation of the dopaminergic sensory afferents of the pns, and/or the disperse dopaminergic elements of central cpgs, into the brain nuclei mediating valuation, reward, and motor arousal; and (6) the urbilaterian possessed the basic circuit relations integrating sensation, internal state, and learning for cost-benefit approach-avoidance decisions. |
2016-12-13 |
2023-08-13 |
Not clear |
| I Mavridi. [The role of the nucleus accumbens in psychiatric disorders]. Psychiatrike = Psychiatriki. vol 25. issue 4. 2016-12-13. PMID:26709994. |
as a functionally central structure between amygdala, basal ganglia, mesolimbic dopaminergic regions, mediodorsal thalamus and prefrontal cortex, the nucleus accumbens appears to play a modulative role in the flow of the information from the amygdaloid complex to these regions. |
2016-12-13 |
2023-08-13 |
human |
| T Mori, Y Iwase, T Saeki, N Iwata, A Murata, D Masukawa, T Suzuk. Differential activation of dopaminergic systems in rat brain basal ganglia by morphine and methamphetamine. Neuroscience. vol 322. 2016-12-13. PMID:26820597. |
differential activation of dopaminergic systems in rat brain basal ganglia by morphine and methamphetamine. |
2016-12-13 |
2023-08-13 |
rat |
| Lars Nyberg, Johan Eriksso. Working Memory: Maintenance, Updating, and the Realization of Intentions. Cold Spring Harbor perspectives in biology. vol 8. issue 2. 2016-10-31. PMID:26637287. |
normal capacity variation, as well as working-memory deficits, can largely be accounted for by the effectiveness and integrity of the basal ganglia and dopaminergic neurotransmission. |
2016-10-31 |
2023-08-13 |
Not clear |
| David Mongeon, Pierre Blanchet, Stéphanie Bergeron, Julie Messie. Impact of Parkinson's disease on proprioceptively based on-line movement control. Experimental brain research. vol 233. issue 9. 2016-10-28. PMID:26055990. |
furthermore, dopaminergic medication did not improve proprioceptively guided movements in pd patients, indicating that dopaminergic dysfunction within the basal ganglia is not solely responsible for these deficits. |
2016-10-28 |
2023-08-13 |
Not clear |
| M W Cunningham, C J Co. Autoimmunity against dopamine receptors in neuropsychiatric and movement disorders: a review of Sydenham chorea and beyond. Acta physiologica (Oxford, England). vol 216. issue 1. 2016-10-21. PMID:26454143. |
the expression of human sc-derived anti-d2r autoantibody v gene in b cells and serum of transgenic mice demonstrated that the human autoantibody targets dopaminergic neurones in the basal ganglia and other types of neurones in the cortex. |
2016-10-21 |
2023-08-13 |
mouse |
| Puneet Bagga, Anup N Chugani, Anant B Pate. Neuroprotective effects of caffeine in MPTP model of Parkinson's disease: A (13)C NMR study. Neurochemistry international. vol 92. 2016-10-17. PMID:26626997. |
parkinson's disease (pd) is a neurodegenerative disorder characterized by degeneration of nigrostriatal dopaminergic neurons with an accompanying neuroinflammation leading to loss of dopamine in the basal ganglia. |
2016-10-17 |
2023-08-13 |
mouse |
| Pedro Costa, Maria José Rosas, Rui Vaz, João Paulo Cunh. Wrist rigidity assessment during Deep Brain Stimulation surgery. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2015. 2016-10-11. PMID:26737028. |
a stimulation electrode is implanted in the basal ganglia to promote the functional control of the deregulated dopaminergic motor pathways. |
2016-10-11 |
2023-08-13 |
Not clear |
| J Belin, J L Houéto, T Constans, C Hommet, B de Toffol, K Mondo. [Geriatric particularities of Parkinson's disease: Clinical and therapeutic aspects]. Revue neurologique. vol 171. issue 12. 2016-09-19. PMID:26573332. |
although historically pd has been characterized by the presence of progressive dopaminergic neuronal loss of the substantia nigra, the disease process also involves neurotransmitters other that dopamine and regions of the nervous system outside the basal ganglia. |
2016-09-19 |
2023-08-13 |
human |
| Hugo González, Francisco Contreras, Rodrigo Pachec. Regulation of the Neurodegenerative Process Associated to Parkinson's Disease by CD4+ T-cells. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 10. issue 4. 2016-09-15. PMID:26018603. |
next, we discussed how alterations of neurotransmitter levels observed in the basal ganglia throughout the time course of pd progression could be strongly affecting the behaviour of encephalitogenic cd4+ t-cells and thereby the outcome of the neuroinflammatory process and the consequent neurodegeneration of dopaminergic neurons. |
2016-09-15 |
2023-08-13 |
Not clear |
| S DeVaughn, E M Müller-Oehring, B Markey, H M Brontë-Stewart, T Schult. Aging with HIV-1 Infection: Motor Functions, Cognition, and Attention--A Comparison with Parkinson's Disease. Neuropsychology review. vol 25. issue 4. 2016-09-09. PMID:26577508. |
although there are clear diagnostic differences in the primary pathology of both diseases, i.e., death of dopamine-generating cells in the substantia nigra in pd and neuroinflammation in hiv, neurotoxicity to dopaminergic terminals in the basal ganglia (bg) has been implied in the pathogenesis of hiv and neuroinflammation in the pathogenesis of pd. |
2016-09-09 |
2023-08-13 |
Not clear |
| Apoorva Gopalakrishna, Sheila A Alexande. Understanding Parkinson Disease: A Complex and Multifaceted Illness. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses. vol 47. issue 6. 2016-09-07. PMID:26528949. |
this article aims to examine in detail the normal function of the basal ganglia and dopaminergic neurons in the central nervous system, the etiology and pathophysiology of parkinson disease, related signs and symptoms, current treatment, and finally, the profound impact of understanding the disease on nursing care. |
2016-09-07 |
2023-08-13 |
Not clear |
| Anne-Marike Schiffer, Alejo J Nevado-Holgado, Andreas Johnen, Anna R Schönberger, Gereon R Fink, Ricarda I Schubot. Intact action segmentation in Parkinson's disease: Hypothesis testing using a novel computational approach. Neuropsychologia. vol 78. 2016-08-04. PMID:26432343. |
because decline of dopaminergic innervation leads to impaired function of the basal ganglia and prefrontal cortex in parkinson's disease (pd), we hypothesised that pd patients would show increased temporal variability in the action segmentation task, especially under medication withdrawal (hypothesis 1). |
2016-08-04 |
2023-08-13 |
human |
| Mona Buhusi, Kaitlin Olsen, Benjamin Z Yang, Catalin V Buhus. Stress-Induced Executive Dysfunction in GDNF-Deficient Mice, A Mouse Model of Parkinsonism. Frontiers in behavioral neuroscience. vol 10. 2016-07-22. PMID:27445722. |
glial-derived neurotrophic factor (gdnf) is essential for regulating dopamine (da) release in the basal ganglia and for the survival of dopaminergic neurons; gdnf-deficient mice are considered an animal model for aging-related parkinsonism. |
2016-07-22 |
2023-08-13 |
mouse |
| Rafieh Alizadeh, Gholamreza Hassanzadeh, Mansoureh Soleimani, Mohammad Taghi Joghataei, Vahid Siavashi, Zhinoos Khorgami, Mahmoudreza Hadjighasse. Gender and age related changes in number of dopaminergic neurons in adult human olfactory bulb. Journal of chemical neuroanatomy. vol 69. 2016-07-20. PMID:26212581. |
dopamine is one of the major brain neurotransmitters, and the loss of dopaminergic neurons in basal ganglia cause motor deficits in parkinson's disease. |
2016-07-20 |
2023-08-13 |
human |
| Mia Apuschkin, Sara Stilling, Troels Rahbek-Clemmensen, Gunnar Sørensen, Guillaume Fortin, Freja Herborg Hansen, Jacob Eriksen, Louis-Eric Trudeau, Kristoffer Egerod, Ulrik Gether, Mattias Rickha. A novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity. The European journal of neuroscience. vol 42. issue 7. 2016-07-20. PMID:26286107. |
midbrain dopaminergic (daergic) neurons are a heterogeneous cell group, composed of functionally distinct cell populations projecting to the basal ganglia, prefrontal cortex and limbic system. |
2016-07-20 |
2023-08-13 |
mouse |
| Magdalena Kurnik, Piotr Tho. The non-motor complications in Parkinson's disease - what can we learn from animal models? Folia medica Cracoviensia. vol 55. issue 2. 2016-07-08. PMID:26839245. |
most of the non-motor symptoms do not correlate with the stage of motor deficits and precede the development of motor symptoms by many years, before the permanent loss of dopaminergic neurons in the basal ganglia. |
2016-07-08 |
2023-08-13 |
human |
| Chiara Baston, Manuela Contin, Giovanna Calandra Buonaura, Pietro Cortelli, Mauro Ursin. A Mathematical Model of Levodopa Medication Effect on Basal Ganglia in Parkinson's Disease: An Application to the Alternate Finger Tapping Task. Frontiers in human neuroscience. vol 10. 2016-07-06. PMID:27378881. |
malfunctions in the neural circuitry of the basal ganglia (bg), induced by alterations in the dopaminergic system, are responsible for an array of motor disorders and milder cognitive issues in parkinson's disease (pd). |
2016-07-06 |
2023-08-13 |
Not clear |