| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pedro A Pereira, Eugénio Gonçalves, Ana Silva, Tiago Millner, M Dulce Madeir. Effects of chronic alcohol consumption and withdrawal on the cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei of the rat: An unbiased stereological study. Neurotoxicology. vol 76. 2021-01-20. PMID:31634498. |
these alterations suggest that the alcohol-induced changes in the brainstem cholinergic nuclei might play a role in the mechanisms underlying the development of addictive behavior to alcohol. |
2021-01-20 |
2023-08-13 |
rat |
| Adam M Kressel, Tea Tsaava, Yaakov A Levine, Eric H Chang, Meghan E Addorisio, Qing Chang, Barry J Burbach, Daniela Carnevale, Giuseppe Lembo, Anthony M Zador, Ulf Andersson, Valentin A Pavlov, Sangeeta S Chavan, Kevin J Trace. Identification of a brainstem locus that inhibits tumor necrosis factor. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 47. 2021-01-19. PMID:33168718. |
these results indicate that cholinergic neurons residing in the brainstem dmn control tnf production, revealing a role for brainstem coordination of immunity. |
2021-01-19 |
2023-08-13 |
Not clear |
| Anjum Parkar, Donald C Fedrigon, Farah Alam, Giancarlo Vanini, George A Mashour, Dinesh Pa. Carbachol and Nicotine in Prefrontal Cortex Have Differential Effects on Sleep-Wake States. Frontiers in neuroscience. vol 14. 2021-01-14. PMID:33328847. |
the role of the brainstem cholinergic system in the regulation of sleep-wake states has been studied extensively but relatively little is known about the role of cholinergic mechanisms in prefrontal cortex in the regulation of sleep-wake states. |
2021-01-14 |
2023-08-13 |
rat |
| Daniel Bertrand, Tanya L Wallac. A Review of the Cholinergic System and Therapeutic Approaches to Treat Brain Disorders. Current topics in behavioral neurosciences. vol 45. 2020-11-09. PMID:32451956. |
within the brain, major cholinergic projection pathways from the basal forebrain and the brainstem support these centrally mediated processes, and dysregulation of the cholinergic system is implicated in cognitive decline associated with aging and dementias including alzheimer's disease. |
2020-11-09 |
2023-08-13 |
Not clear |
| Ismini Rozani, Georgia Tsapara, Emily C Witts, S James Deaville, Gareth B Miles, Laskaro Zagoraio. Pitx2 cholinergic interneurons are the source of C bouton synapses on brainstem motor neurons. Scientific reports. vol 9. issue 1. 2020-10-15. PMID:30894556. |
pitx2 cholinergic interneurons are the source of c bouton synapses on brainstem motor neurons. |
2020-10-15 |
2023-08-13 |
mouse |
| Ismini Rozani, Georgia Tsapara, Emily C Witts, S James Deaville, Gareth B Miles, Laskaro Zagoraio. Pitx2 cholinergic interneurons are the source of C bouton synapses on brainstem motor neurons. Scientific reports. vol 9. issue 1. 2020-10-15. PMID:30894556. |
taken together, our data present important new information about the anatomical organization of cholinergic systems which impact motor systems of the brainstem. |
2020-10-15 |
2023-08-13 |
mouse |
| Matthew W O'Malley, Subimal Datt. REM Sleep Regulating Mechanisms in the Cholinergic Cell Compartment of the Brainstem. Indian journal of sleep medicine. vol 8. issue 2. 2020-10-01. PMID:25400382. |
rem sleep regulating mechanisms in the cholinergic cell compartment of the brainstem. |
2020-10-01 |
2023-08-13 |
Not clear |
| Bernd Fritzsch, Karen L Elliot. Evolution and Development of the Inner Ear Efferent System: Transforming a Motor Neuron Population to Connect to the Most Unusual Motor Protein via Ancient Nicotinic Receptors. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:28484373. |
experimental transplantations mimicking this possible aspect of ear evolution showed that different motor neurons of the spinal cord or brainstem form cholinergic synapses on hair cells when ears replace somites or eyes. |
2020-10-01 |
2023-08-13 |
Not clear |
| Sung Ho Jang, Jeong Pyo Se. Diffusion Tensor Tractography Studies on Injured Anterior Cingulum Recovery Mechanisms: A Mini-Review. Frontiers in neurology. vol 9. 2020-10-01. PMID:30581414. |
the recovery mechanisms of the injured anterior cinguli reported in those 10 studies are classified as follows: mechanism 1, recovery via the normal pathway of the cingulum between the injured cingulum and ch 4; mechanism 2, recovery through the neural tract between the injured cingulum and the brainstem cholinergic nuclei; mechanism 3, recovery via the lateral cholinergic pathway between the injured cingulum and the white matter of the temporo-occipital lobes; mechanism 4, recovery through the neural tract between the contralesional basal forebrain and the ipsilesional basal forebrain via the genu of the corpus callosum; and mechanism 5, recovery through the neural tract between the injured cingulum and ch 4 via an aberrant pathway. |
2020-10-01 |
2023-08-13 |
human |
| Sun Young Lim, Yi-Sub Kwa. Effect of nutrients and exhaustive exercise on brain function. Journal of exercise rehabilitation. vol 15. issue 3. 2020-10-01. PMID:31316924. |
endurance physical exercise and energy restriction was also recognized of cardiovascular stress adjustment by enhancing brainstem cholinergic activity as well as brain function. |
2020-10-01 |
2023-08-13 |
human |
| Fumika Mori, Ken-Ichi Okada, Taishin Nomura, Yasushi Kobayash. The Pedunculopontine Tegmental Nucleus as a Motor and Cognitive Interface between the Cerebellum and Basal Ganglia. Frontiers in neuroanatomy. vol 10. 2020-09-30. PMID:27872585. |
as an important component of ascending activating systems, brainstem cholinergic neurons in the pedunculopontine tegmental nucleus (pptg) are involved in the regulation of motor control (locomotion, posture and gaze) and cognitive processes (attention, learning and memory). |
2020-09-30 |
2023-08-13 |
Not clear |
| Amanda Clause, Amanda M Lauer, Karl Kandle. Mice Lacking the Alpha9 Subunit of the Nicotinic Acetylcholine Receptor Exhibit Deficits in Frequency Difference Limens and Sound Localization. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28663725. |
sound processing in the cochlea is modulated by cholinergic efferent axons arising from medial olivocochlear neurons in the brainstem. |
2020-09-30 |
2023-08-13 |
mouse |
| Anna Maria Lavezz. Toxic Effect of Cigarette Smoke on Brainstem Nicotinic Receptor Expression: Primary Cause of Sudden Unexplained Perinatal Death. Toxics. vol 6. issue 4. 2020-09-29. PMID:30340403. |
among the neurotoxicants contained in tobacco smoke, if absorbed during pregnancy, nicotine significantly affects α7-nicotinic acetylcholine receptors, which play essential roles in the development of the brainstem regions receiving cholinergic projections in perinatal life. |
2020-09-29 |
2023-08-13 |
Not clear |
| Miao Ren, Jiaojiao Tian, Peilin Zhao, Jialiang Luo, Zhao Feng, Hui Gong, Xiangning L. Simultaneous Acquisition of Multicolor Information From Neural Circuits in Resin-Embedded Samples. Frontiers in neuroscience. vol 12. 2020-09-29. PMID:30555296. |
input cholinergic terminals from the pptg were found to innervate the cholinergic soma and fiber in the neocortex, basal forebrain and brainstem, indicating that local cholinergic neurons received long-range cholinergic modulation from the midbrain. |
2020-09-29 |
2023-08-13 |
Not clear |
| Raj Kumar Tiwari, Vikas Sharma, Ravindra Kumar Pandey, Shiv Shankar Shukl. Nicotine Addiction: Neurobiology and Mechanism. Journal of pharmacopuncture. vol 23. issue 1. 2020-09-28. PMID:32322429. |
neurological systems such as gabaergic, serotonergic, noradrenergic, and brain stem cholinergic may also be involved to mediate the actions of nicotine. |
2020-09-28 |
2023-08-13 |
Not clear |
| Nobuyuki Eura, Takeshi K Matsui, Joachim Luginbühl, Masaya Matsubayashi, Hitoki Nanaura, Tomo Shiota, Kaoru Kinugawa, Naohiko Iguchi, Takao Kiriyama, Canbin Zheng, Tsukasa Kouno, Yan Jun Lan, Pornparn Kongpracha, Pattama Wiriyasermkul, Yoshihiko M Sakaguchi, Riko Nagata, Tomoya Komeda, Naritaka Morikawa, Fumika Kitayoshi, Miyong Jong, Shinko Kobashigawa, Mari Nakanishi, Masatoshi Hasegawa, Yasuhiko Saito, Takashi Shiromizu, Yuhei Nishimura, Takahiko Kasai, Maiko Takeda, Hiroshi Kobayashi, Yusuke Inagaki, Yasuhito Tanaka, Manabu Makinodan, Toshifumi Kishimoto, Hiroki Kuniyasu, Shushi Nagamori, Alysson R Muotri, Jay W Shin, Kazuma Sugie, Eiichiro Mor. Brainstem Organoids From Human Pluripotent Stem Cells. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32670003. |
here, we developed a method to generate human brainstem organoids (hbsos), containing midbrain/hindbrain progenitors, noradrenergic and cholinergic neurons, dopaminergic neurons, and neural crest lineage cells. |
2020-09-28 |
2023-08-13 |
human |
| P Marcos, R Coveña. Neuroanatomical relationship between the cholinergic and tachykininergic systems in the adult human brainstem: An immunohistochemical study. Journal of chemical neuroanatomy. vol 102. 2020-09-14. PMID:31585148. |
neuroanatomical relationship between the cholinergic and tachykininergic systems in the adult human brainstem: an immunohistochemical study. |
2020-09-14 |
2023-08-13 |
human |
| Paul Albert Fuchs, Amanda M Laue. Efferent Inhibition of the Cochlea. Cold Spring Harbor perspectives in medicine. vol 9. issue 5. 2020-09-11. PMID:30082454. |
cholinergic efferent neurons originating in the brainstem innervate the acoustico-lateralis organs (inner ear, lateral line) of vertebrates. |
2020-09-11 |
2023-08-13 |
human |
| Marina R Davis, Jennifer L Magnusson, Kevin J Cumming. Increased central cholinergic drive contributes to the apneas of serotonin-deficient rat pups during active sleep. Journal of applied physiology (Bethesda, Md. : 1985). vol 126. issue 5. 2020-09-08. PMID:30763168. |
given that cholinergic neurons are drivers of active sleep and project to respiratory patterning regions in the brainstem, we hypothesized that 5-ht preserves respiratory stability in active sleep by dampening central cholinergic drive. |
2020-09-08 |
2023-08-13 |
rat |
| Christoph Stein, Konrad Koch, Julia Hopfeld, Sebastian Lobentanzer, Helene Lau, Jochen Klei. Impaired hippocampal and thalamic acetylcholine release in P301L tau-transgenic mice. Brain research bulletin. vol 152. 2020-08-14. PMID:31323279. |
three brain regions were compared: hippocampus and thalamus which receive cholinergic input from the basal forebrain, and the red nucleus which receives cholinergic projections from brain stem nuclei. |
2020-08-14 |
2023-08-13 |
mouse |