| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sergio Vicencio-Jimenez, Madison M Weinberg, Giuliana Bucci-Mansilla, Amanda M Laue. Olivocochlear Changes Associated With Aging Predominantly Affect the Medial Olivocochlear System. Frontiers in neuroscience. vol 15. 2021-09-21. PMID:34539335. |
we assessed, in young-adult and aged cba mice, the number of cholinergic olivocochlear neurons, auditory brainstem response (abr) thresholds in silence and in presence of background noise, and the expression of excitatory and inhibitory proteins in the ventral nucleus of the trapezoid body (vntb) and in the lateral superior olive (lso). |
2021-09-21 |
2023-08-13 |
mouse |
| Nichole L Beebe, Chao Zhang, R Michael Burger, Brett R Schofiel. Multiple Sources of Cholinergic Input to the Superior Olivary Complex. Frontiers in neural circuits. vol 15. 2021-09-18. PMID:34335196. |
such projections present an opportunity for cholinergic modulation to be coordinated across the auditory brainstem. |
2021-09-18 |
2023-08-13 |
Not clear |
| Guela Sokhadze, Kyle L Whyland, Martha E Bickford, William Guid. The organization of cholinergic projections in the visual thalamus of the mouse. The Journal of comparative neurology. 2021-09-08. PMID:34448209. |
cholinergic projections from the brainstem serve as important modulators of activity in visual thalamic nuclei such as the dorsal lateral geniculate nucleus (dlgn). |
2021-09-08 |
2023-08-13 |
mouse |
| Guela Sokhadze, Kyle L Whyland, Martha E Bickford, William Guid. The organization of cholinergic projections in the visual thalamus of the mouse. The Journal of comparative neurology. 2021-09-08. PMID:34448209. |
we used the retrograde transport of viruses or cholera toxin subunit b (ctb) injected in the dlgn, immunocytochemical labeling with antibodies against choline acetyltransferase (chat), brain nitric oxide synthase (bnos), and vesicular acetylcholine transporter (vacht), chat-cre mice crossed with a reporter line (ai9), as well as brainstem virus injections in chat-cre mice to examine the pattern of thalamic innervation from cholinergic neurons in the pedunculopontine tegmental nucleus (pptg), laterodorsal tegmental nucleus (ldtg), and the parabigeminal nucleus (pbg). |
2021-09-08 |
2023-08-13 |
mouse |
| Taketoshi Sugimura, Yasuhiko Sait. Distinct proportions of cholinergic neurons in the rat prepositus hypoglossi nucleus according to their cerebellar projection targets. The Journal of comparative neurology. vol 529. issue 7. 2021-08-16. PMID:32949021. |
although the prepositus hypoglossi nucleus (phn), a brainstem structure involved in controlling gaze holding, is known as one of the major sources of these cholinergic inputs, the proportions of cholinergic neurons in phn projections to distinct cerebellar regions have not been quantitatively analyzed. |
2021-08-16 |
2023-08-13 |
rat |
| Glenn T Schneider, Choongheon Lee, Anjali K Sinha, Paivi M Jordan, Joseph C Hol. The mammalian efferent vestibular system utilizes cholinergic mechanisms to excite primary vestibular afferents. Scientific reports. vol 11. issue 1. 2021-08-13. PMID:33441862. |
to determine if activation of ach receptors account for efferent-mediated afferent excitation in mammals, we recorded afferent activity from the superior vestibular nerve of anesthetized c57bl/6 mice while stimulating evs neurons in the brainstem, before and after administration of cholinergic antagonists. |
2021-08-13 |
2023-08-13 |
mouse |
| Marianne Amalric, Tommy Pattij, Ioannis Sotiropoulos, Joana M Silva, Nuno Sousa, Samira Ztaou, Cristiano Chiamulera, Lars U Wahlberg, Dwaine F Emerich, Giovanna Paolon. Where Dopaminergic and Cholinergic Systems Interact: A Gateway for Tuning Neurodegenerative Disorders. Frontiers in behavioral neuroscience. vol 15. 2021-08-10. PMID:34366802. |
among subcortical structures, the dopaminergic nigrostriatal and mesolimbic pathways as well as cholinergic innervation from basal forebrain and brainstem, play pivotal roles in orchestrating cognitive and non-cognitive symptoms in pd and ad. |
2021-08-10 |
2023-08-13 |
human |
| Pilar Marcos, Rafael Coveña. Immunohistochemical study of the brainstem cholinergic system in the alpaca (Lama pacos) and colocalization with CGRP. European journal of histochemistry : EJH. vol 65. issue s1. 2021-08-07. PMID:34346665. |
immunohistochemical study of the brainstem cholinergic system in the alpaca (lama pacos) and colocalization with cgrp. |
2021-08-07 |
2023-08-13 |
Not clear |
| Pilar Marcos, Rafael Coveña. Immunohistochemical study of the brainstem cholinergic system in the alpaca (Lama pacos) and colocalization with CGRP. European journal of histochemistry : EJH. vol 65. issue s1. 2021-08-07. PMID:34346665. |
several cholinergic regions have been detected in the brainstem of mammals. |
2021-08-07 |
2023-08-13 |
Not clear |
| Pilar Marcos, Rafael Coveña. Immunohistochemical study of the brainstem cholinergic system in the alpaca (Lama pacos) and colocalization with CGRP. European journal of histochemistry : EJH. vol 65. issue s1. 2021-08-07. PMID:34346665. |
the cholinergic system of the brainstem has been partially described in cetartiodactyla, except for the medulla oblongata. |
2021-08-07 |
2023-08-13 |
Not clear |
| Pilar Marcos, Rafael Coveña. Immunohistochemical study of the brainstem cholinergic system in the alpaca (Lama pacos) and colocalization with CGRP. European journal of histochemistry : EJH. vol 65. issue s1. 2021-08-07. PMID:34346665. |
comparing the present results with others previously obtained by our group regarding the catecholaminergic system in the alpaca brainstem, it seems that cgrp may be more functionally related to the latter system than to the cholinergic system. |
2021-08-07 |
2023-08-13 |
Not clear |
| Maxime Assou. Striatal cholinergic transmission. Focus on nicotinic receptors' influence in striatal circuits. The European journal of neuroscience. vol 53. issue 8. 2021-06-29. PMID:33529401. |
striatal cholinergic interneurons (cins) are responsible for the bulk of striatal ach, although extrinsic cholinergic afferents from brainstem structures may also play a role. |
2021-06-29 |
2023-08-13 |
Not clear |
| Pedro A Pereira, Joana Coelho, Ana Silva, M Dulce Madeir. Effects of aging on the cholinergic innervation of the rat ventral tegmental area: A stereological study. Experimental gerontology. vol 148. 2021-06-02. PMID:33652122. |
dopamine neurons in the ventral tegmental area (vta) play a main role in processing both rewarding and aversive stimuli, and their response to salient stimuli is significantly shaped by afferents originating in the brainstem cholinergic nuclei. |
2021-06-02 |
2023-08-13 |
rat |
| Pedro Renato P Brandão, Renato Puppi Munhoz, Talyta Cortez Grippe, Francisco Eduardo Costa Cardoso, Brenda Macedo de Almeida E Castro, Ricardo Titze-de-Almeida, Carlos Tomaz, Maria Clotilde Henriques Tavare. Cognitive impairment in Parkinson's disease: A clinical and pathophysiological overview. Journal of the neurological sciences. vol 419. 2021-05-14. PMID:33068906. |
here we overview the scientific literature on the role of functional circuits, neurotransmitter systems (monoaminergic and cholinergic), basal forebrain, and brainstem nuclei dysfunction in pd-mci. |
2021-05-14 |
2023-08-13 |
Not clear |
| Yugandhar Ramakrishna, Marco Manca, Elisabeth Glowatzki, Soroush G Sadegh. Cholinergic Modulation of Membrane Properties of Calyx Terminals in the Vestibular Periphery. Neuroscience. vol 452. 2021-05-14. PMID:33197502. |
calyces have an abundance of different subtypes of kcnq (kv7) potassium channels and muscarinic acetylcholine receptors (machrs) and receive cholinergic efferent inputs from neurons in the brainstem. |
2021-05-14 |
2023-08-13 |
rat |
| Nicole Buie, Dharm Sodha, Sarah B Scheinman, Stephan Steid. Rewarding effects of M4 but not M3 muscarinic cholinergic receptor antagonism in the rostromedial tegmental nucleus. Behavioural brain research. vol 379. 2021-04-30. PMID:31697984. |
the rostromedial tegmental nucleus (rmtg) receives inputs from the laterodorsal tegmental and pedunculopontine tegmental nuclei, the two principle brainstem cholinergic nuclei. |
2021-04-30 |
2023-08-13 |
mouse |
| Sandra Iglesias, Lars Kasper, Samuel J Harrison, Robert Manka, Christoph Mathys, Klaas E Stepha. Cholinergic and dopaminergic effects on prediction error and uncertainty responses during sensory associative learning. NeuroImage. vol 226. 2021-03-01. PMID:33285332. |
however, we found pharmacological effects on brain activity associated with these computational quantities only when splitting the precision-weighted pes into their pe and precision components: in a brainstem region putatively containing cholinergic (pedunculopontine and laterodorsal tegmental) nuclei, biperiden (compared to placebo) enhanced low-level pe responses and attenuated high-level pe activity, while amisulpride reduced high-level pe responses. |
2021-03-01 |
2023-08-13 |
human |
| Pedro A Pereira, Eugénio Gonçalves, Ana Silva, Tiago Millner, M Dulce Madeir. Effects of chronic alcohol consumption and withdrawal on the cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei of the rat: An unbiased stereological study. Neurotoxicology. vol 76. 2021-01-20. PMID:31634498. |
the brain cholinergic system comprises two main recognized subdivisions, the basal forebrain and the brainstem cholinergic systems. |
2021-01-20 |
2023-08-13 |
rat |
| Pedro A Pereira, Eugénio Gonçalves, Ana Silva, Tiago Millner, M Dulce Madeir. Effects of chronic alcohol consumption and withdrawal on the cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei of the rat: An unbiased stereological study. Neurotoxicology. vol 76. 2021-01-20. PMID:31634498. |
the effects of chronic alcohol consumption on the basal forebrain cholinergic nuclei have been investigated extensively, but there is only one study that has examined those effects on the brainstem cholinergic nuclei. |
2021-01-20 |
2023-08-13 |
rat |
| Pedro A Pereira, Eugénio Gonçalves, Ana Silva, Tiago Millner, M Dulce Madeir. Effects of chronic alcohol consumption and withdrawal on the cholinergic neurons of the pedunculopontine and laterodorsal tegmental nuclei of the rat: An unbiased stereological study. Neurotoxicology. vol 76. 2021-01-20. PMID:31634498. |
these results show that prolonged exposure to ethanol leads to long-lasting, and potentially irreversible, cytoarchitectonic and neurochemical alterations in the brainstem cholinergic nuclei. |
2021-01-20 |
2023-08-13 |
rat |