| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pietro Gareri, Pasquale De Fazio, Salvatore De Fazio, Norma Marigliano, Guido Ferreri Ibbadu, Giovambattista De Sarr. Adverse effects of atypical antipsychotics in the elderly: a review. Drugs & aging. vol 23. issue 12. 2007-05-01. PMID:17154659. |
new antipsychotics, such as amisulpride, clozapine, olanzapine, risperidone, quetiapine, ziprasidone, zotepine and aripiprazole, may interact with both dopamine and serotonin receptors. |
2007-05-01 |
2023-08-12 |
Not clear |
| Shinya Uchida, Yasuhiro Kato, Kazufumi Hirano, Yoshiyuki Kagawa, Shizuo Yamad. Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol, risperidone and olanzapine. Life sciences. vol 80. issue 17. 2007-05-01. PMID:17316700. |
the present study was conducted to characterize the binding of neurotransmitter receptors (dopamine d(2), serotonin 5-ht(2), histamine h(1), adrenaline alpha(1) and muscarine m(l) receptors) in the rat's brain after the oral administration of haloperidol, risperidone, and olanzapine. |
2007-05-01 |
2023-08-12 |
rat |
| Shinya Uchida, Yasuhiro Kato, Kazufumi Hirano, Yoshiyuki Kagawa, Shizuo Yamad. Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol, risperidone and olanzapine. Life sciences. vol 80. issue 17. 2007-05-01. PMID:17316700. |
in contrast, risperidone (0.1-3 mg/kg) showed roughly 30 times more affinity for the 5-ht(2) receptor than d(2) receptor. |
2007-05-01 |
2023-08-12 |
rat |
| Shinya Uchida, Yasuhiro Kato, Kazufumi Hirano, Yoshiyuki Kagawa, Shizuo Yamad. Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol, risperidone and olanzapine. Life sciences. vol 80. issue 17. 2007-05-01. PMID:17316700. |
in conclusion, haloperidol and risperidone administered orally selectively bind d(2) and 5-ht(2) receptors, respectively, in the rat brain, while olanzapine binds h(1), 5-ht(2), and d(2) receptors more than alpha(1) and m(1) receptors. |
2007-05-01 |
2023-08-12 |
rat |
| Lei Wang, Lan Yu, Guang He, Jing Zhang, Ai-Ping Zhang, Jing Du, Rui-Qi Tang, Xin-Zhi Zhao, Jie Ma, Jie-Kun Xuan, Yue Xiao, Niu-Fan Gu, Guo-Ying Feng, Ming-Qing Xu, Qing-He Xing, Lin H. Response of risperidone treatment may be associated with polymorphisms of HTT gene in Chinese schizophrenia patients. Neuroscience letters. vol 414. issue 1. 2007-04-27. PMID:17287080. |
few studies have focused on polymorphisms of the serotonin transporter and antipsychotic response and, in particular, there have so far been no published studies on the association between the serotonin transporter and response to risperidone. |
2007-04-27 |
2023-08-12 |
Not clear |
| Lei Wang, Lan Yu, Guang He, Jing Zhang, Ai-Ping Zhang, Jing Du, Rui-Qi Tang, Xin-Zhi Zhao, Jie Ma, Jie-Kun Xuan, Yue Xiao, Niu-Fan Gu, Guo-Ying Feng, Ming-Qing Xu, Qing-He Xing, Lin H. Response of risperidone treatment may be associated with polymorphisms of HTT gene in Chinese schizophrenia patients. Neuroscience letters. vol 414. issue 1. 2007-04-27. PMID:17287080. |
this study examined the relationship between two polymorphisms of the serotonin transporter and the efficacy of risperidone treatment in 129 patients with schizophrenia. |
2007-04-27 |
2023-08-12 |
Not clear |
| M Reimold, C Solbach, S Noda, J-E Schaefer, M Bartels, M Beneke, H-J Machulla, R Bares, T Glaser, H Wormstal. Occupancy of dopamine D(1), D (2) and serotonin (2A) receptors in schizophrenic patients treated with flupentixol in comparison with risperidone and haloperidol. Psychopharmacology. vol 190. issue 2. 2007-03-30. PMID:17111172. |
occupancy of dopamine d(1), d (2) and serotonin (2a) receptors in schizophrenic patients treated with flupentixol in comparison with risperidone and haloperidol. |
2007-03-30 |
2023-08-12 |
Not clear |
| M Reimold, C Solbach, S Noda, J-E Schaefer, M Bartels, M Beneke, H-J Machulla, R Bares, T Glaser, H Wormstal. Occupancy of dopamine D(1), D (2) and serotonin (2A) receptors in schizophrenic patients treated with flupentixol in comparison with risperidone and haloperidol. Psychopharmacology. vol 190. issue 2. 2007-03-30. PMID:17111172. |
in vitro data show comparable affinity to dopamine d(2), d(1) and 5-ht(2a) receptors and recently, flx showed to be not inferior to risperidone in schizophrenic patients with predominant negative symptomatology, which was implicated with flupentixol's interaction with 5-ht(2a) and/or d(1) receptors. |
2007-03-30 |
2023-08-12 |
Not clear |
| Kabrena E Rodda, Olaf H Drumme. The redistribution of selected psychiatric drugs in post-mortem cases. Forensic science international. vol 164. issue 2-3. 2007-03-16. PMID:16554130. |
drugs detected included five selective serotonin reuptake inhibitors; venlafaxine, a serotonin/noradrenaline reuptake inhibitor; and risperidone, an atypical antipsychotic. |
2007-03-16 |
2023-08-12 |
Not clear |
| Carol Smith, Tariq Rahman, Nicole Toohey, Joseph Mazurkiewicz, Katharine Herrick-Davis, Milt Teitle. Risperidone irreversibly binds to and inactivates the h5-HT7 serotonin receptor. Molecular pharmacology. vol 70. issue 4. 2006-11-29. PMID:16870886. |
pretreatment of the cells with 5 or 20 nm risperidone, followed by removal of the drug from the media, renders the 5-ht7 receptors unresponsive to 10 microm 5-ht for at least 24 h. thus, risperidone seems to be producing a rapid, long-lasting inactivation of the h5-ht7 receptor. |
2006-11-29 |
2023-08-12 |
Not clear |
| Wayne K Goodman, Eric A Storch, Gary R Geffken, Tanya K Murph. Obsessive-compulsive disorder in Tourette syndrome. Journal of child neurology. vol 21. issue 8. 2006-11-21. PMID:16970872. |
cases of obsessive-compulsive disorder that do not sufficiently improve with serotonin reuptake inhibitors might benefit from adjunctive low-dose antipsychotic (eg, risperidone) medication whether or not tics are present. |
2006-11-21 |
2023-08-12 |
Not clear |
| Taylor Moran-Gates, Carla Massari, Amaury Graulich, Jean-François Liégeois, Frank I Taraz. Long-term effects of JL 13, a potential atypical antipsychotic, on rat dopamine and serotonin receptor subtypes. Journal of neuroscience research. vol 84. issue 3. 2006-11-01. PMID:16810690. |
changes in dopamine (da) d(1), d(2), d(3), and d(4) receptors and serotonin 5-ht(1a) and 5-ht(2a) receptors in rat forebrain regions were autoradiographically quantified after continuous infusion of jl 13 [(5-(4-methylpiperazin-1-yl)-8-chloro-pyrido[2,3-b][1,5]benzoxazepine fumarate] for 28 days with osmotic minipumps and compared with the effects of other typical (fluphenazine) and atypical (clozapine, olanzapine, and risperidone) antipsychotic drugs from previous studies. |
2006-11-01 |
2023-08-12 |
rat |
| Mei Huang, Junji Ichiwaka, Zhu Li, Jin Dai, Herbert Y Meltze. Augmentation by citalopram of risperidone-induced monoamine release in rat prefrontal cortex. Psychopharmacology. vol 185. issue 3. 2006-09-29. PMID:16521036. |
olanzapine and risperidone, have been reported to be effective adjunctive treatment for depression if selective serotonin (5-ht) reuptake inhibitors (ssris) alone are ineffective. |
2006-09-29 |
2023-08-12 |
rat |
| Hsien-Yuan Lane, Cheng-Chun Lee, Yi-Ching Liu, Wen-Ho Chan. Pharmacogenetic studies of response to risperidone and other newer atypical antipsychotics. Pharmacogenomics. vol 6. issue 2. 2006-09-28. PMID:15882132. |
recent studies suggest that the 5-hydroxytryptamine receptor 2a (5-ht2a) gene (htr2a) t102c and g-1438a polymorphisms may influence treatment response of risperidone or olanzapine for schizophrenia's negative symptoms (e.g., blunted affect and social withdrawal). |
2006-09-28 |
2023-08-12 |
Not clear |
| Philip J Tyson, Keith R Laws, Kenneth A Flowers, Agi Tyson, Ann M Mortime. Cognitive function and social abilities in patients with schizophrenia: relationship with atypical antipsychotics. Psychiatry and clinical neurosciences. vol 60. issue 4. 2006-09-20. PMID:16884450. |
comparisons were done for matched schizophrenia patients who were on antipsychotics with (i) an affinity for multiple receptors (olanzapine, clozapine, quetiapine) versus those that have preferential affinity for dopamine receptors (risperidone, amisulpride); and patients on medication with (ii) a high affinity for serotonin (5ht-2a) receptors (risperidone, olanzapine, clozapine) versus those with a low (or no) affinity for 5ht-2a receptors (quetiapine, amisulpride). |
2006-09-20 |
2023-08-12 |
Not clear |
| Monte S Buchsbaum, Eric Hollander, Stefano Pallanti, Nicolò Baldini Rossi, Jimcy Platholi, Randall Newmark, Rachel Bloom, Erica Soo. Positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients. Neuropsychobiology. vol 53. issue 3. 2006-09-14. PMID:16707915. |
positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients. |
2006-09-14 |
2023-08-12 |
Not clear |
| Monte S Buchsbaum, Eric Hollander, Stefano Pallanti, Nicolò Baldini Rossi, Jimcy Platholi, Randall Newmark, Rachel Bloom, Erica Soo. Positron emission tomography imaging of risperidone augmentation in serotonin reuptake inhibitor-refractory patients. Neuropsychobiology. vol 53. issue 3. 2006-09-14. PMID:16707915. |
we studied 15 nondepressed patients with obsessive-compulsive disorder (ocd) who were nonresponders to serotonin reuptake inhibitors with an additive trial of risperidone. |
2006-09-14 |
2023-08-12 |
Not clear |
| F Arias Horcajadas, J A Soto, M J García-Cantalapiedra, J L Rodríguez Calvin, J Morales, M Salgad. [Effectiveness and tolerability of addition of risperidone in obsessive-compulsive disorder with poor response to serotonin reuptake inhibitors]. Actas espanolas de psiquiatria. vol 34. issue 3. 2006-08-03. PMID:16736387. |
[effectiveness and tolerability of addition of risperidone in obsessive-compulsive disorder with poor response to serotonin reuptake inhibitors]. |
2006-08-03 |
2023-08-12 |
Not clear |
| Reiji Yoshimura, Sachiko Kaneko, Koji Shinkai, Jun Nakamur. Successful treatment for obsessive-compulsive disorder with addition of low-dose risperidone to fluvoxamine: implications for plasma levels of catecholamine metabolites and serum brain-derived neurotrophic factor levels. Psychiatry and clinical neurosciences. vol 60. issue 3. 2006-07-26. PMID:16732759. |
in short, fluvoxamine enhances the activity of the serotonergic system by inhibiting serotonin transporters, and risperidone decreases that of the dopaminergic system by blocking d2 receptors. |
2006-07-26 |
2023-08-12 |
Not clear |
| Jan van der Weide, Erica H van Baalen-Benedek, Jenny E Kootstra-Ro. Metabolic ratios of psychotropics as indication of cytochrome P450 2D6/2C19 genotype. Therapeutic drug monitoring. vol 27. issue 4. 2006-04-25. PMID:16044105. |
to serve as an example for different groups of medications, the selective serotonin reuptake inhibitor venlafaxine, the tricyclic antidepressant amitriptyline, and the antipsychotic risperidone were studied to examine a possible correlation between the mrs of these drugs and the cyp2c19 and/or cyp2d6 genotype. |
2006-04-25 |
2023-08-12 |
human |