| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eleanor J Bull, Peter H Hutson, Kevin C F Fon. Decreased social behaviour following 3,4-methylenedioxymethamphetamine (MDMA) is accompanied by changes in 5-HT2A receptor responsivity. Neuropharmacology. vol 46. issue 2. 2004-05-28. PMID:14680758. |
on pnd 92, hippocampal, frontal cortical and striatal 5-hydroxytryptamine (5-ht) was significantly reduced in mdma pre-treated rats by between 16% and 22%, without any accompanying change in [(3)h]paroxetine binding in cortical homogenates. |
2004-05-28 |
2023-08-12 |
rat |
| F Herbst, L Gortne. [Paroxetine withdrawal syndrome as differential diagnosis of acute neonatal encephalopathy?]. Zeitschrift fur Geburtshilfe und Neonatologie. vol 207. issue 6. 2004-05-20. PMID:14689334. |
paroxetine, a selective serotonin reuptake inhibitor (ssri) may be given in severe cases of maternal depression and panic disorders during pregnancy. |
2004-05-20 |
2023-08-12 |
Not clear |
| Damiaan Denys, Huibert Burger, Harold van Megen, Femke de Geus, Herman Westenber. A score for predicting response to pharmacotherapy in obsessive-compulsive disorder. International clinical psychopharmacology. vol 18. issue 6. 2004-05-19. PMID:14571151. |
one hundred and fifty patients with primary ocd according to dsm-iv criteria were randomly assigned in a 12-week, double-blind, comparison trial with a selective serotonin reuptake inhibitor (paroxetine), and a serotonin-noradrenaline reuptake inhibitor (venlafaxine). |
2004-05-19 |
2023-08-12 |
Not clear |
| V N Kozyrev, A B Smulevich, M Iu Drobizhev, G K Kraeva, M A Kubrako. [Psychotropic drugs used in a psychiatric hospital (pharmaco-epidemiologic aspects)]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 103. issue 11. 2004-05-14. PMID:14681962. |
selective inhibitors of serotonin reuptake (paroxetine, fluoxetine, citalopram, sertraline), reversible mao a inhibitors (pyrazidolum), "double-action" drugs (mirtazapine, milnacipran) are recommended for wider usage. |
2004-05-14 |
2023-08-12 |
Not clear |
| Larissa I Velez, Greene Shepherd, Brett A Roth, Fernando L Benite. Serotonin syndrome with elevated paroxetine concentrations. The Annals of pharmacotherapy. vol 38. issue 2. 2004-05-11. PMID:14742765. |
serotonin syndrome with elevated paroxetine concentrations. |
2004-05-11 |
2023-08-12 |
Not clear |
| Larissa I Velez, Greene Shepherd, Brett A Roth, Fernando L Benite. Serotonin syndrome with elevated paroxetine concentrations. The Annals of pharmacotherapy. vol 38. issue 2. 2004-05-11. PMID:14742765. |
to describe a case of serotonin syndrome due to paroxetine and ethanol. |
2004-05-11 |
2023-08-12 |
Not clear |
| Alan Lenox-Smith, Pete Conway, Chris Knigh. Cost effectiveness of representatives of three classes of antidepressants used in major depression in the UK. PharmacoEconomics. vol 22. issue 5. 2004-05-11. PMID:15061681. |
three classes of antidepressants (serotonin and noradrenaline reuptake inhibitors [snris; venlafaxine], selective serotonin reuptake inhibitors [ssris; fluoxetine, paroxetine and fluvoxamine] and tricyclic antidepressants [tcas; amitriptyline]) were compared by populating the tree with clinical success rates determined by a meta-analysis and a clinical trial. |
2004-05-11 |
2023-08-12 |
Not clear |
| Wenzhen Duan, Zhihong Guo, Haiyang Jiang, Bruce Ladenheim, Xiangru Xu, Jean Lud Cadet, Mark P Mattso. Paroxetine retards disease onset and progression in Huntingtin mutant mice. Annals of neurology. vol 55. issue 4. 2004-05-07. PMID:15048901. |
we report that administration of paroxetine, a widely prescribed antidepressant drug that acts by inhibiting reuptake of the neurotransmitter serotonin, suppresses the neurodegenerative process and increases the survival of huntingtin mutant mice, an animal model of huntington's disease (hd). |
2004-05-07 |
2023-08-12 |
mouse |
| Yusuke Ochiai, Hisatoshi Katsu, Shinji Okino, Noriyuki Wakutsu, Kazuhiko Nakayam. [Case of prolonged recovery from serotonin syndrome caused by paroxetine]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 105. issue 12. 2004-05-06. PMID:15027311. |
[case of prolonged recovery from serotonin syndrome caused by paroxetine]. |
2004-05-06 |
2023-08-12 |
Not clear |
| Yusuke Ochiai, Hisatoshi Katsu, Shinji Okino, Noriyuki Wakutsu, Kazuhiko Nakayam. [Case of prolonged recovery from serotonin syndrome caused by paroxetine]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 105. issue 12. 2004-05-06. PMID:15027311. |
we report a case of serotonin syndrome in a patient being treated with paroxetine for depression. |
2004-05-06 |
2023-08-12 |
Not clear |
| Yusuke Ochiai, Hisatoshi Katsu, Shinji Okino, Noriyuki Wakutsu, Kazuhiko Nakayam. [Case of prolonged recovery from serotonin syndrome caused by paroxetine]. Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica. vol 105. issue 12. 2004-05-06. PMID:15027311. |
on admission, change of mental condition (consciousness disturbance), perspiration, hyperreflexia, myoclonus and tremor were seen, and serotonin syndrome caused by paroxetine was suspected. |
2004-05-06 |
2023-08-12 |
Not clear |
| Roberta Pacifici, Simona Pichini, Piergiorgio Zuccaro, Magí Farré, Mireia Segura, Jordi Ortuño, Simonetta Di Carlo, Antonella Bacosi, Pere N Roset, Jordi Segura, Rafael de la Torr. Paroxetine inhibits acute effects of 3,4-methylenedioxymethamphetamine on the immune system in humans. The Journal of pharmacology and experimental therapeutics. vol 309. issue 1. 2004-05-04. PMID:14722327. |
mdma-induced alterations in the immune system as well as antagonistic effects mediated by paroxetine show a trend toward baseline levels at 24 h. these findings suggest that acute effects of mdma on immune system are mainly mediated by its interaction with the serotonin transporter and subsequent serotonin release with a possible participation of other neuroendocrine regulatory systems. |
2004-05-04 |
2023-08-12 |
human |
| Bruno P Guiard, Cédric Przybylski, Jean-Philippe Guilloux, Isabelle Seif, Nicolas Froger, Carmen De Felipe, Stephen P Hunt, Laurence Lanfumey, Alain M Gardie. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. Journal of neurochemistry. vol 89. issue 1. 2004-04-26. PMID:15030389. |
the aim of the present study was to evaluate the effects of coadministration of the selective 5-ht reuptake inhibitor (ssri) paroxetine with a nk1 receptor antagonist (gr205171 or l733060), given either intraperitoneally (i.p.) |
2004-04-26 |
2023-08-12 |
mouse |
| Bruno P Guiard, Cédric Przybylski, Jean-Philippe Guilloux, Isabelle Seif, Nicolas Froger, Carmen De Felipe, Stephen P Hunt, Laurence Lanfumey, Alain M Gardie. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. Journal of neurochemistry. vol 89. issue 1. 2004-04-26. PMID:15030389. |
), potentiated the effects of paroxetine on cortical [5-ht]ext in wild-type mice, whereas gr205171 (30 mg/kg; i.p.) |
2004-04-26 |
2023-08-12 |
mouse |
| Bruno P Guiard, Cédric Przybylski, Jean-Philippe Guilloux, Isabelle Seif, Nicolas Froger, Carmen De Felipe, Stephen P Hunt, Laurence Lanfumey, Alain M Gardie. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. Journal of neurochemistry. vol 89. issue 1. 2004-04-26. PMID:15030389. |
when gr205171 (300 micro mol/l) was perfused by 'reverse microdialysis' into the dorsal raphe nucleus, it potentiated the effects of paroxetine on cortical [5-ht]ext, and inhibited paroxetine-induced increase in [5-ht]ext in the dorsal raphe nucleus. |
2004-04-26 |
2023-08-12 |
mouse |
| Bruno P Guiard, Cédric Przybylski, Jean-Philippe Guilloux, Isabelle Seif, Nicolas Froger, Carmen De Felipe, Stephen P Hunt, Laurence Lanfumey, Alain M Gardie. Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice. Journal of neurochemistry. vol 89. issue 1. 2004-04-26. PMID:15030389. |
finally, in mice whose 5-ht transporters were first blocked by a local perfusion of 1 micro mol/l of citalopram into the frontal cortex, a single dose of paroxetine (4 mg/kg i.p.) |
2004-04-26 |
2023-08-12 |
mouse |
| Martin M Katz, Janet L Tekell, Charles L Bowden, Steve Brannan, John P Houston, Nancy Berman, Alan Fraze. Onset and early behavioral effects of pharmacologically different antidepressants and placebo in depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 3. 2004-04-14. PMID:14627997. |
the first goal was to identify, during the first 2 weeks of treatment, the onset of clinical actions of the selective serotonin reuptake inhibitor (ssri), paroxetine, and the selective noradrenergic reuptake inhibitor, desipramine (dmi). |
2004-04-14 |
2023-08-12 |
Not clear |
| Vikram Kumar Yeragani, Radhakrishna Rao, Manuel Tancer, Thomas Uhd. Paroxetine decreases respiratory irregularity of linear and nonlinear measures of respiration in patients with panic disorder. A preliminary report. Neuropsychobiology. vol 49. issue 2. 2004-04-12. PMID:14981334. |
in this study, we evaluated the effects of a serotonin reuptake inhibitor, paroxetine, on respiratory variability in patients with panic disorder (n = 13), using linear and nonlinear measures of regularity, approximate entropy (apen) and a measure of chaos, the largest lyapunov exponent (lle), with pre- and posttreatment lung volume time series (256 s long sampled at 4 hz). |
2004-04-12 |
2023-08-12 |
Not clear |
| Ashwin A Patkar, Edward Gottheil, Wade H Berrettini, Kevin P Hill, Charles C Thornton, Stephen P Weinstei. Relationship between platelet serotonin uptake sites and measures of impulsivity, aggression, and craving among African-American cocaine abusers. The American journal on addictions. vol 12. issue 5. 2004-04-06. PMID:14660157. |
we investigated whether platelet-tritiated paroxetine binding, a measure of serotonin uptake sites, and behavioral measures of impulsivity, aggression, and craving differed between cocaine-dependent subjects and controls and whether paroxetine binding was related to these behavioral measures. |
2004-04-06 |
2023-08-12 |
human |
| Ripu D Jindal, Edward S Friedman, Susan R Berman, Amy L Fasiczka, Robert H Howland, Michael E Thas. Effects of sertraline on sleep architecture in patients with depression. Journal of clinical psychopharmacology. vol 23. issue 6. 2004-03-19. PMID:14624183. |
previous studies indicate that selective serotonin reuptake inhibitors (ssris), including fluoxetine, fluvoxamine, citalopram and paroxetine, suppress rapid eye movement sleep, and increased nocturnal arousals. |
2004-03-19 |
2023-08-12 |
Not clear |