| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hakim Houchi, Daniela Babovic, Olivier Pierrefiche, Catherine Ledent, Martine Daoust, Mickaël Naassil. CB1 receptor knockout mice display reduced ethanol-induced conditioned place preference and increased striatal dopamine D2 receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 2. 2005-02-15. PMID:15383833. |
altogether, the present results indicate that lifelong deletion of cb1 receptors reduced ethanol-induced cpp and that these reduced rewarding effects of ethanol are correlated to an overexpression of striatal dopamine d2 receptors. |
2005-02-15 |
2023-08-12 |
mouse |
| Thomas J H Chen, Kenneth Blum, James T Payte, John Schoolfield, David Hopper, Mathew Stanford, Eric R Braverma. Narcotic antagonists in drug dependence: pilot study showing enhancement of compliance with SYN-10, amino-acid precursors and enkephalinase inhibition therapy. Medical hypotheses. vol 63. issue 3. 2005-02-10. PMID:15288384. |
78 (2001) 1094] and associates found increases in the dopamine d2 receptors (drd2) via adenoviral vector delivery of the drd2 gene into the nucleus accumbens, significantly reduced both ethanol preference (43%) and alcohol intake (64%) of ethanol preferring rats, which recovered as the drd2, returned to baseline levels. |
2005-02-10 |
2023-08-12 |
human |
| Michael N Smolka, Henning Budde, Anne C Karow, Lutz G Schmid. Neuroendocrinological and neuropsychological correlates of dopaminergic function in nicotine dependence. Psychopharmacology. vol 175. issue 3. 2005-02-02. PMID:15114432. |
there is multiple evidence that nicotine--as with ethanol and other drugs of abuse--stimulates dopamine release in the ventral striatum as a central part of the brain reward circuits. |
2005-02-02 |
2023-08-12 |
Not clear |
| Sara González, Marta Valenti, Rosario de Miguel, Filomena Fezza, Javier Fernández-Ruiz, Vincenzo Di Marzo, José A Ramo. Changes in endocannabinoid contents in reward-related brain regions of alcohol-exposed rats, and their possible relevance to alcohol relapse. British journal of pharmacology. vol 143. issue 4. 2005-02-01. PMID:15371286. |
accordingly, none of these effects on ethanol intake were accompanied by changes in dopamine and gaba in limbic structures. |
2005-02-01 |
2023-08-12 |
rat |
| L Judson Chandler, Antonello Bonci, Gary S Wand, Richard A Morriset. Recent advances in cyclic-adenosine monophosphate/protein kinase A signaling in ethanol-induced synaptic and behavioral alterations. Alcoholism, clinical and experimental research. vol 28. issue 7. 2005-01-19. PMID:15252301. |
the presentations were (1) pka regulates chronic ethanol-induced synaptic targeting of nmda receptors, by l. judson chandler; (2) long-lasting potentiation of gabaergic synapses in dopamine neurons after a single in vivo ethanol exposure, by antonello bonci; (3) the darpp-32 cascade and regulation of the ethanol sensitivity of nmda receptors in the nucleus accumbens, by richard a. morrisett; (4) and the camp/pka signal transduction pathway modulates ethanol consumption and sedative effects of ethanol, by gary s. wand. |
2005-01-19 |
2023-08-12 |
Not clear |
| J Donaldson, F S LaBella, D Gesse. Enhanced autoxidation of dopamine as a possible basis of manganese neurotoxicity. Neurotoxicology. vol 2. issue 1. 2005-01-19. PMID:15622724. |
manganese-enhanced autoxidation of dopamine was associated with increased generation of the free radicals o2-, h2o2, and ho as suggested by the inhibitory effects of superoxide dismutase, catalase and ethanol. |
2005-01-19 |
2023-08-12 |
Not clear |
| Seong Shoon Yoon, Young Kyu Kwon, Mi Ryeo Kim, Insop Shim, Kwang Joong Kim, Mann Hyung Lee, Young Sun Lee, Gregory T Golden, Chae Ha Yan. Acupuncture-mediated inhibition of ethanol-induced dopamine release in the rat nucleus accumbens through the GABAB receptor. Neuroscience letters. vol 369. issue 3. 2005-01-13. PMID:15464271. |
these results suggest that stimulation of specific acupoints inhibits ethanol-induced dopamine release by modulating gaba(b) activity and imply that acupuncture may be effective in blocking the reinforcing effects of ethanol. |
2005-01-13 |
2023-08-12 |
rat |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
the role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. |
2005-01-07 |
2023-08-12 |
Not clear |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
although forced ethanol administration enhances dopamine activity in the nacc, conclusions regarding the role of mesolimbic dopamine in ethanol reinforcement cannot be made from these experiments. |
2005-01-07 |
2023-08-12 |
Not clear |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
behavioral experiments consistently show that pharmacological manipulations of the dopamine transmission in the nacc alter responding for ethanol, although ethanol reinforcement is maintained after lesions of the accumbal dopamine system. |
2005-01-07 |
2023-08-12 |
Not clear |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
additionally, extracellular dopamine increases in the nacc during operant self-administration of ethanol, which is consistent with a role of dopamine in ethanol reinforcement. |
2005-01-07 |
2023-08-12 |
Not clear |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
behavioral studies that distinguish appetitive responding from ethanol consumption show that dopamine is important in ethanol-seeking behavior, whereas neurochemical studies suggest that accumbal dopamine is also important during ethanol consumption before pharmacological effects occur. |
2005-01-07 |
2023-08-12 |
Not clear |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
thus, anatomical, pharmacological, neurochemical, cellular, and behavioral studies are more clearly defining the role of mesolimbic dopamine in ethanol reinforcement. |
2005-01-07 |
2023-08-12 |
Not clear |
| Roberto I Melendez, Zachary A Rodd, William J McBride, James M Murph. Involvement of the mesopallidal dopamine system in ethanol reinforcement. Alcohol (Fayetteville, N.Y.). vol 32. issue 2. 2004-12-27. PMID:15163564. |
the current study was designed to test the hypothesis that acquisition of signal-induced anticipation of self-administered ethanol and operant oral self-administration of ethanol increases the extracellular levels of dopamine in the ventral pallidum of alcohol-preferring (p) rats. |
2004-12-27 |
2023-08-12 |
rat |
| Roberto I Melendez, Zachary A Rodd, William J McBride, James M Murph. Involvement of the mesopallidal dopamine system in ethanol reinforcement. Alcohol (Fayetteville, N.Y.). vol 32. issue 2. 2004-12-27. PMID:15163564. |
the ethanol group showed significant increases in extracellular levels of dopamine in the ventral pallidum during (1). |
2004-12-27 |
2023-08-12 |
rat |
| M Waly, H Olteanu, R Banerjee, S-W Choi, J B Mason, B S Parker, S Sukumar, S Shim, A Sharma, J M Benzecry, V-A Power-Charnitsky, R C Det. Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Molecular psychiatry. vol 9. issue 4. 2004-12-22. PMID:14745455. |
ethanol potently interfered with igf-1 activation of ms and blocked its effect on dna methylation, whereas it did not inhibit the effects of dopamine. |
2004-12-22 |
2023-08-12 |
human |
| A Clark, H J Littl. Interactions between low concentrations of ethanol and nicotine on firing rate of ventral tegmental dopamine neurones. Drug and alcohol dependence. vol 75. issue 2. 2004-12-07. PMID:15276226. |
interactions between low concentrations of ethanol and nicotine on firing rate of ventral tegmental dopamine neurones. |
2004-12-07 |
2023-08-12 |
Not clear |
| Christian A Heidbreder, Michela Andreoli, Clara Marcon, Panayotis K Thanos, Charles R Ashby, Eliot L Gardne. Role of dopamine D3 receptors in the addictive properties of ethanol. Drugs of today (Barcelona, Spain : 1998). vol 40. issue 4. 2004-10-13. PMID:15190388. |
role of dopamine d3 receptors in the addictive properties of ethanol. |
2004-10-13 |
2023-08-12 |
Not clear |
| Christian A Heidbreder, Michela Andreoli, Clara Marcon, Panayotis K Thanos, Charles R Ashby, Eliot L Gardne. Role of dopamine D3 receptors in the addictive properties of ethanol. Drugs of today (Barcelona, Spain : 1998). vol 40. issue 4. 2004-10-13. PMID:15190388. |
the present review is intended to highlight a new, promising area in alcohol research that focuses on the role of the dopamine d(3) receptor in the addictive properties of ethanol. |
2004-10-13 |
2023-08-12 |
Not clear |
| K Choong, R She. Prenatal ethanol exposure alters the postnatal development of the spontaneous electrical activity of dopamine neurons in the ventral tegmental area. Neuroscience. vol 126. issue 4. 2004-10-08. PMID:15207341. |
prenatal ethanol exposure alters the postnatal development of the spontaneous electrical activity of dopamine neurons in the ventral tegmental area. |
2004-10-08 |
2023-08-12 |
Not clear |