Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
William M Doyon, Vorani Ramachandra, Herman H Samson, Cristine L Czachowski, Rueben A Gonzale. Accumbal dopamine concentration during operant self-administration of a sucrose or a novel sucrose with ethanol solution. Alcohol (Fayetteville, N.Y.). vol 34. issue 2-3. 2005-07-11. PMID:15902921. |
microdialysis samples were collected before, during, and after bar pressing and drinking, and content of ethanol and dopamine was determined. |
2005-07-11 |
2023-08-12 |
rat |
William M Doyon, Vorani Ramachandra, Herman H Samson, Cristine L Czachowski, Rueben A Gonzale. Accumbal dopamine concentration during operant self-administration of a sucrose or a novel sucrose with ethanol solution. Alcohol (Fayetteville, N.Y.). vol 34. issue 2-3. 2005-07-11. PMID:15902921. |
however, after consumption began, dopamine concentration increased in the sucrose, but not in the sucrose with ethanol, group, followed by a return to baseline values. |
2005-07-11 |
2023-08-12 |
rat |
William M Doyon, Vorani Ramachandra, Herman H Samson, Cristine L Czachowski, Rueben A Gonzale. Accumbal dopamine concentration during operant self-administration of a sucrose or a novel sucrose with ethanol solution. Alcohol (Fayetteville, N.Y.). vol 34. issue 2-3. 2005-07-11. PMID:15902921. |
these results demonstrate that operant self-administration of sucrose increases accumbal dopamine concentration during consummatory phases of behavior, but that a similar increase is not apparent when a novel, perhaps aversive, solution (sucrose with ethanol) is presented. |
2005-07-11 |
2023-08-12 |
rat |
William M Doyon, Vorani Ramachandra, Herman H Samson, Cristine L Czachowski, Rueben A Gonzale. Accumbal dopamine concentration during operant self-administration of a sucrose or a novel sucrose with ethanol solution. Alcohol (Fayetteville, N.Y.). vol 34. issue 2-3. 2005-07-11. PMID:15902921. |
in addition, oral self-administration of ethanol at 0.27 +/- 0.02 g/kg over 20 min is not sufficient for stimulation of dopamine activity in the nucleus accumbens. |
2005-07-11 |
2023-08-12 |
rat |
M V Pivovarchi. [Change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 76. issue 2. 2005-06-17. PMID:15915718. |
[change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. |
2005-06-17 |
2023-08-12 |
rat |
M V Pivovarchi. [Change of dopamine, serotonin and opioid neuromediator systems in the brain of rats adapted to prolonged effect of ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 76. issue 2. 2005-06-17. PMID:15915718. |
to investigate the effect of in vivo short-term ethanol administration (i.p., 1.5 g/kg, 6 h) on binding characteristics of opioid receptor agonists in rat midbrain, as well as the contents of dopamine, serotonin and their precursors and metabolites in midbrain, striatum and hypothalamus of rats after long-term alcohol consumption. |
2005-06-17 |
2023-08-12 |
rat |
Panayotis K Thanos, Seth N Rivera, Katrina Weaver, David K Grandy, Marcelo Rubinstein, Hiroyuki Umegaki, Gene Jack Wang, Robert Hitzemann, Nora D Volko. Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking. Life sciences. vol 77. issue 2. 2005-06-02. PMID:15862598. |
dopamine d2r dna transfer in dopamine d2 receptor-deficient mice: effects on ethanol drinking. |
2005-06-02 |
2023-08-12 |
mouse |
Anna Molander, Bo Söderpal. Accumbal strychnine-sensitive glycine receptors: an access point for ethanol to the brain reward system. Alcoholism, clinical and experimental research. vol 29. issue 1. 2005-05-25. PMID:15654288. |
ethanol (etoh), like other drugs of abuse, increases extracellular dopamine (da) levels in the nucleus accumbens (nac) of the brain reward system, an effect that may be of importance for alcohol addiction. |
2005-05-25 |
2023-08-12 |
Not clear |
Anna Molander, Elin Löf, Rosita Stomberg, Mia Ericson, Bo Söderpal. Involvement of accumbal glycine receptors in the regulation of voluntary ethanol intake in the rat. Alcoholism, clinical and experimental research. vol 29. issue 1. 2005-05-25. PMID:15654289. |
extracellular dopamine (da) levels in the nucleus accumbens (nac) increase after ethanol (etoh) administration in the rat, a response that may be involved in the positive reinforcing effects of etoh. |
2005-05-25 |
2023-08-12 |
rat |
S M M Vasconcelos, R A Cavalcante, L M V Aguiar, F C F Sousa, M M F Fonteles, G S B Vian. Effects of chronic ethanol treatment on monoamine levels in rat hippocampus and striatum. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 37. issue 12. 2005-05-19. PMID:15558190. |
we studied the effects of ethanol on concentrations of noradrenaline (ne), dopamine (da) and serotonin (5-ht) and their metabolites in rat hippocampus and striatum. |
2005-05-19 |
2023-08-12 |
rat |
Abdalla Bowirrat, Marlene Oscar-Berma. Relationship between dopaminergic neurotransmission, alcoholism, and Reward Deficiency syndrome. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 132B. issue 1. 2005-05-12. PMID:15457501. |
although other neurotransmitters (e.g., glutamate, gamma-aminobutyric acid (gaba), and serotonin) may be important in determining the rewarding and stimulating effects of ethanol, dopamine may be critical for initiating drug use and for reinstating drug use during protracted abstinence. |
2005-05-12 |
2023-08-12 |
Not clear |
William J McBride, Richard L Bell, Zachary A Rodd, Wendy N Strother, James M Murph. Adolescent alcohol drinking and its long-range consequences. Studies with animal models. Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism. vol 17. 2005-05-03. PMID:15789863. |
the early age-of-onset of alcohol drinking in the p compared to the np line is associated with (a) higher densities of serotonin-1a (5-ht1a) receptors in cerebral cortical and hippocampal regions; (b) lower densities of dopamine (da) d2 receptors in the ventral tegmental area (vta); (c) higher functional activity in several limbic, cortical and hippocampal regions; and (d) sensitivity to the low-dose stimulating effect of ethanol. |
2005-05-03 |
2023-08-12 |
rat |
Sonya K Sobrian, Barbara L Jones, Hutchinson James, Feremusu N Kamara, R Robert Holso. Prenatal ethanol preferentially enhances reactivity of the dopamine D1 but not D2 or D3 receptors in offspring. Neurotoxicology and teratology. vol 27. issue 1. 2005-05-02. PMID:15681123. |
prenatal ethanol preferentially enhances reactivity of the dopamine d1 but not d2 or d3 receptors in offspring. |
2005-05-02 |
2023-08-12 |
human |
P Rada, D F Johnson, M J Lewis, B G Hoebe. In alcohol-treated rats, naloxone decreases extracellular dopamine and increases acetylcholine in the nucleus accumbens: evidence of opioid withdrawal. Pharmacology, biochemistry, and behavior. vol 79. issue 4. 2005-04-29. PMID:15582668. |
as with the withdrawal from morphine, nicotine, diazepam and sugar, the ethanol withdrawal state may involve an increase in nucleus accumbens (nac) acetylcholine (ach) causing an alteration of the dopamine (da)-ach balance in favor of ach. |
2005-04-29 |
2023-08-12 |
rat |
Philip Seeman, David Weinshenker, Remi Quirion, Lalit K Srivastava, Sanjeev K Bhardwaj, David K Grandy, Richard T Premont, Tatyana D Sotnikova, Patricia Boksa, Mufida El-Ghundi, Brian F O'dowd, Susan R George, Melissa L Perreault, Pekka T Männistö, Siobhan Robinson, Richard D Palmiter, Teresa Talleric. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 9. 2005-04-13. PMID:15716360. |
dopamine supersensitivity occurs in schizophrenia and other psychoses, and after hippocampal lesions, antipsychotics, ethanol, amphetamine, phencyclidine, gene knockouts of dbh (dopamine beta-hydroxylase), drd4 receptors, gprk6 (g protein-coupled receptor kinase 6), comt (catechol-o-methyltransferase), or th-/-, dbhth/+ (tyrosine hydroxylase), and in rats born by cesarean-section. |
2005-04-13 |
2023-08-12 |
rat |
Erkki Tupala, Jari Tiihone. Dopamine and alcoholism: neurobiological basis of ethanol abuse. Progress in neuro-psychopharmacology & biological psychiatry. vol 28. issue 8. 2005-03-07. PMID:15588749. |
dopamine and alcoholism: neurobiological basis of ethanol abuse. |
2005-03-07 |
2023-08-12 |
human |
Kimber L Price, Lawrence D Middaug. The dopamine D1 antagonist reduces ethanol reward for C57BL/6 mice. Alcoholism, clinical and experimental research. vol 28. issue 11. 2005-03-01. PMID:15547453. |
the dopamine d1 antagonist reduces ethanol reward for c57bl/6 mice. |
2005-03-01 |
2023-08-12 |
mouse |
Kimber L Price, Lawrence D Middaug. The dopamine D1 antagonist reduces ethanol reward for C57BL/6 mice. Alcoholism, clinical and experimental research. vol 28. issue 11. 2005-03-01. PMID:15547453. |
dopamine d1 antagonist effects on behaviors related to obtaining and consuming ethanol remain unclear. |
2005-03-01 |
2023-08-12 |
mouse |
P F Foley, E W Loh, D J Innes, S M Williams, A E G Tannenberg, C G Harper, P R Dod. Association studies of neurotransmitter gene polymorphisms in alcoholic Caucasians. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542698. |
ethanol enhances mesolimbic/cortical dopamine activity in reward and reinforcement circuits. |
2005-02-18 |
2023-08-12 |
Not clear |
P F Foley, E W Loh, D J Innes, S M Williams, A E G Tannenberg, C G Harper, P R Dod. Association studies of neurotransmitter gene polymorphisms in alcoholic Caucasians. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542698. |
we investigated the hypothesis that risk for alcoholism may be mediated by genes for neurotransmitters associated with the dopamine reward system as well as genes for enzymes involved in ethanol metabolism. |
2005-02-18 |
2023-08-12 |
Not clear |