| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jerome Jeanblanc, Dao-Yao He, Nancy N H McGough, Marian L Logrip, Khanhky Phamluong, Patricia H Janak, Dorit Ro. The dopamine D3 receptor is part of a homeostatic pathway regulating ethanol consumption. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 5. 2006-04-27. PMID:16452669. |
we also find that increases in the levels of bdnf, mediated by ethanol or rack1, lead to increased dorsal striatal levels of the dopamine d3 receptor (d3r), a gene downstream of bdnf, via activation of the trkb receptor. |
2006-04-27 |
2023-08-12 |
mouse |
| Jerome Jeanblanc, Dao-Yao He, Nancy N H McGough, Marian L Logrip, Khanhky Phamluong, Patricia H Janak, Dorit Ro. The dopamine D3 receptor is part of a homeostatic pathway regulating ethanol consumption. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 5. 2006-04-27. PMID:16452669. |
finally, we show that the tat-rack1-mediated reduction of ethanol consumption is attenuated by coinjection with either the trk inhibitor k252a or the dopamine d3r-prefering antagonist u-99194a [5, 6-dimethoxy-2-(di-n-propylamino)indan], suggesting that activation of the bdnf pathway via rack1 leads to increased expression of the dopamine d3r, which in turn mediates the attenuation of ethanol consumption. |
2006-04-27 |
2023-08-12 |
mouse |
| Robnet T Kerns, Ajay Ravindranathan, Sajida Hassan, Mary P Cage, Tim York, James M Sikela, Robert W Williams, Michael F Mile. Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 9. 2006-03-31. PMID:15745951. |
activation of the mesolimbic dopamine reward pathway by acute ethanol produces reinforcement and changes in gene expression that appear to be crucial to the molecular basis for adaptive behaviors and addiction. |
2006-03-31 |
2023-08-12 |
mouse |
| Rong Jie Zhao, Seong Shoon Yoon, Bong Hyo Lee, Young Kyu Kwon, Kwang Joong Kim, Insop Shim, Kwang-Ho Choi, Mi Ryeo Kim, Gregory T Golden, Chae Ha Yan. Acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16289320. |
acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats. |
2006-03-29 |
2023-08-12 |
rat |
| Rong Jie Zhao, Seong Shoon Yoon, Bong Hyo Lee, Young Kyu Kwon, Kwang Joong Kim, Insop Shim, Kwang-Ho Choi, Mi Ryeo Kim, Gregory T Golden, Chae Ha Yan. Acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16289320. |
it is well known that chronic administration of ethanol may produce depletion or sensitization of extracellular dopamine levels in the nucleus accumbens. |
2006-03-29 |
2023-08-12 |
rat |
| Rong Jie Zhao, Seong Shoon Yoon, Bong Hyo Lee, Young Kyu Kwon, Kwang Joong Kim, Insop Shim, Kwang-Ho Choi, Mi Ryeo Kim, Gregory T Golden, Chae Ha Yan. Acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16289320. |
acupuncture at the specific acupoint ht7, but not at control points (pc6 or tail) significantly prevented both a decrease of extracellular dopamine levels in the nucleus accumbens during ethanol withdrawal and an increase in accumbal dopamine levels induced by the ethanol challenge. |
2006-03-29 |
2023-08-12 |
rat |
| Rong Jie Zhao, Seong Shoon Yoon, Bong Hyo Lee, Young Kyu Kwon, Kwang Joong Kim, Insop Shim, Kwang-Ho Choi, Mi Ryeo Kim, Gregory T Golden, Chae Ha Yan. Acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats. Neuroscience letters. vol 395. issue 1. 2006-03-29. PMID:16289320. |
these results provided strong evidence that stimulation of the specific acupoint ht7 helps to normalize the release of dopamine in the mesolimbic system following chronic ethanol treatment. |
2006-03-29 |
2023-08-12 |
rat |
| Luciano C Batista, Rui D S Prediger, Gina S Morato, Reinaldo N Takahash. Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice. Psychopharmacology. vol 181. issue 4. 2006-03-02. PMID:15983797. |
blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice. |
2006-03-02 |
2023-08-12 |
mouse |
| Luciano C Batista, Rui D S Prediger, Gina S Morato, Reinaldo N Takahash. Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice. Psychopharmacology. vol 181. issue 4. 2006-03-02. PMID:15983797. |
several reports have suggested the involvement of brain adenosine and dopamine receptors in different actions produced by ethanol such as motor incoordination or anxiolytic, hypnotic and reinforcing effects. |
2006-03-02 |
2023-08-12 |
mouse |
| Takashi Okamoto, Mark T Harnett, Hitoshi Morikaw. Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice. Journal of neurophysiology. vol 95. issue 2. 2006-02-28. PMID:16148268. |
hyperpolarization-activated cation current (ih) is an ethanol target in midbrain dopamine neurons of mice. |
2006-02-28 |
2023-08-12 |
mouse |
| Takashi Okamoto, Mark T Harnett, Hitoshi Morikaw. Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice. Journal of neurophysiology. vol 95. issue 2. 2006-02-28. PMID:16148268. |
ethanol stimulates the firing activity of midbrain dopamine (da) neurons, leading to enhanced dopaminergic transmission in the mesolimbic system. |
2006-02-28 |
2023-08-12 |
mouse |
| Carl R Lupica, Mark S Brodi. Queer currents, steady rhythms, and drunken da neurons. Focus on "hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice". Journal of neurophysiology. vol 95. issue 2. 2006-02-28. PMID:16424449. |
focus on "hyperpolarization-activated cation current (ih) is an ethanol target in midbrain dopamine neurons of mice". |
2006-02-28 |
2023-08-12 |
mouse |
| Evgeny A Budygin, Tiffany A Mathews, Gennady B Lapa, Sara R Jone. Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice. European journal of pharmacology. vol 523. issue 1-3. 2006-02-16. PMID:16226738. |
local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in c57bl/6 mice. |
2006-02-16 |
2023-08-12 |
mouse |
| Evgeny A Budygin, Tiffany A Mathews, Gennady B Lapa, Sara R Jone. Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice. European journal of pharmacology. vol 523. issue 1-3. 2006-02-16. PMID:16226738. |
in this study, fast-scan cyclic voltammetry in brain slices was used to evaluate the effects of acute ethanol on dopamine terminal release and uptake in the nucleus accumbens of c57bl/6 mice. |
2006-02-16 |
2023-08-12 |
mouse |
| Evgeny A Budygin, Tiffany A Mathews, Gennady B Lapa, Sara R Jone. Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice. European journal of pharmacology. vol 523. issue 1-3. 2006-02-16. PMID:16226738. |
we found that pharmacologically relevant concentrations of ethanol (20 and 100 mm) did not alter electrically evoked dopamine release, while the highest concentration (200 mm) significantly decreased release (approximately 45%). |
2006-02-16 |
2023-08-12 |
mouse |
| Evgeny A Budygin, Tiffany A Mathews, Gennady B Lapa, Sara R Jone. Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice. European journal of pharmacology. vol 523. issue 1-3. 2006-02-16. PMID:16226738. |
no significant changes were observed in the rate of dopamine uptake after ethanol (20, 100 or 200 mm). |
2006-02-16 |
2023-08-12 |
mouse |
| Evgeny A Budygin, Tiffany A Mathews, Gennady B Lapa, Sara R Jone. Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice. European journal of pharmacology. vol 523. issue 1-3. 2006-02-16. PMID:16226738. |
of ethanol did not alter the rate of dopamine synthesis, measured as l-dihydroxyphenylalanine (l-dopa) accumulation. |
2006-02-16 |
2023-08-12 |
mouse |
| Evgeny A Budygin, Tiffany A Mathews, Gennady B Lapa, Sara R Jone. Local effects of acute ethanol on dopamine neurotransmission in the ventral striatum in C57BL/6 mice. European journal of pharmacology. vol 523. issue 1-3. 2006-02-16. PMID:16226738. |
these data are consistent with earlier findings obtained in brain slices from rats; dopamine release, but not clearance, is affected by acute ethanol. |
2006-02-16 |
2023-08-12 |
mouse |
| Michael S Cowen, Cameron Adams, Tracey Kraehenbuehl, Valentina Vengeliene, Andrew J Lawrenc. The acute anti-craving effect of acamprosate in alcohol-preferring rats is associated with modulation of the mesolimbic dopamine system. Addiction biology. vol 10. issue 3. 2006-02-08. PMID:16109584. |
interestingly, acute acamprosate was also shown to cause increased dopamine transporter density and decreased dopamine d2-like receptor density within the nucleus accumbens but not in the caudate-putamen, suggesting a link between the decreased motivational salience of the ethanol cue and altered dopaminergic signalling within the nucleus accumbens. |
2006-02-08 |
2023-08-12 |
human |
| Anna Larsson, Lena Edström, Lennart Svensson, Bo Söderpalm, Jörgen A Enge. Voluntary ethanol intake increases extracellular acetylcholine levels in the ventral tegmental area in the rat. Alcohol and alcoholism (Oxford, Oxfordshire). vol 40. issue 5. 2006-01-11. PMID:16043436. |
in previous animal experiments, we have demonstrated that nicotinic acetylcholine receptors, especially alpha-conotoxin mii and mecamylamine sensitive receptors located in the ventral tegmental area may be involved in the stimulatory, dopamine enhancing, and rewarding effects of ethanol in rodents. |
2006-01-11 |
2023-08-12 |
human |