| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Izco, Ivanny Marchant, Isabel Escobedo, Ines Peraile, Mercedes Delgado, Alejandro Higuera-Matas, Oscar Olias, Emilio Ambrosio, Esther O'Shea, M Isabel Colad. Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") exhibit increased ethanol consumption and preference. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17526809. |
using a two-bottle free-choice paradigm, we examined the voluntary consumption and preference for ethanol in mice deficient in cerebral dopamine concentration and dopamine transporter density by previous repeated mdma administration. |
2007-10-19 |
2023-08-12 |
mouse |
| Maria Izco, Ivanny Marchant, Isabel Escobedo, Ines Peraile, Mercedes Delgado, Alejandro Higuera-Matas, Oscar Olias, Emilio Ambrosio, Esther O'Shea, M Isabel Colad. Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") exhibit increased ethanol consumption and preference. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17526809. |
intraperitoneal administration of ethanol elevated extracellular dopamine release in the nucleus accumbens of saline-treated mice, but this effect was almost abolished in mdma-treated mice. |
2007-10-19 |
2023-08-12 |
mouse |
| Maria Izco, Ivanny Marchant, Isabel Escobedo, Ines Peraile, Mercedes Delgado, Alejandro Higuera-Matas, Oscar Olias, Emilio Ambrosio, Esther O'Shea, M Isabel Colad. Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") exhibit increased ethanol consumption and preference. The Journal of pharmacology and experimental therapeutics. vol 322. issue 3. 2007-10-19. PMID:17526809. |
these results indicate that mice with reduced dopamine activity following a neurotoxic dose of mdma exhibit increased ethanol consumption and preference and suggest that animals might need to consume more alcohol to reach the threshold for the rewarding effects of ethanol. |
2007-10-19 |
2023-08-12 |
mouse |
| Yuichiro Inoue, Lina Yao, F Woodward Hopf, Peidong Fan, Zhan Jiang, Antonello Bonci, Ivan Diamon. Nicotine and ethanol activate protein kinase A synergistically via G(i) betagamma subunits in nucleus accumbens/ventral tegmental cocultures: the role of dopamine D(1)/D(2) and adenosine A(2A) receptors. The Journal of pharmacology and experimental therapeutics. vol 322. issue 1. 2007-08-30. PMID:17468300. |
nicotine and ethanol activate protein kinase a synergistically via g(i) betagamma subunits in nucleus accumbens/ventral tegmental cocultures: the role of dopamine d(1)/d(2) and adenosine a(2a) receptors. |
2007-08-30 |
2023-08-12 |
Not clear |
| Zachary A Rodd, Victoria E Gryszowka, Jamie E Toalston, Scott M Oster, Dong Ji, Richard L Bell, William J McBrid. The reinforcing actions of a serotonin-3 receptor agonist within the ventral tegmental area: evidence for subregional and genetic differences and involvement of dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 321. issue 3. 2007-07-30. PMID:17325230. |
studies from our laboratory indicated that local perfusion of the ventral tegmental area (vta) with a serotonin-3 (5-ht(3)) receptor agonist increased dopamine (da) neuronal activity and that the self-infusion of ethanol (etoh) and cocaine into the posterior vta could be inhibited with coadministration of a 5-ht(3) receptor antagonist. |
2007-07-30 |
2023-08-12 |
rat |
| Anna Molander, Helga Höifödt Lidö, Elin Löf, Mia Ericson, Bo Söderpal. The glycine reuptake inhibitor Org 25935 decreases ethanol intake and preference in male wistar rats. Alcohol and alcoholism (Oxford, Oxfordshire). vol 42. issue 1. 2007-06-26. PMID:17098748. |
previous findings from our group indicate that accumbal glycine receptors (glyrs) are involved in mediating the dopamine (da) activating effects of ethanol (etoh), and that administration of glycine locally into the nucleus accumbens (nac) reduces etoh consumption in etoh high-preferring rats. |
2007-06-26 |
2023-08-12 |
rat |
| Kimberly A Badanich, Antoniette M Maldonado, Cheryl L Kirstei. Chronic ethanol exposure during adolescence increases basal dopamine in the nucleus accumbens septi during adulthood. Alcoholism, clinical and experimental research. vol 31. issue 5. 2007-05-22. PMID:17391340. |
chronic ethanol exposure during adolescence increases basal dopamine in the nucleus accumbens septi during adulthood. |
2007-05-22 |
2023-08-12 |
Not clear |
| Kimberly A Badanich, Antoniette M Maldonado, Cheryl L Kirstei. Chronic ethanol exposure during adolescence increases basal dopamine in the nucleus accumbens septi during adulthood. Alcoholism, clinical and experimental research. vol 31. issue 5. 2007-05-22. PMID:17391340. |
the aim of the present study was to address whether chronic ethanol exposure during adolescence would alter nucleus accumbens septi (nacc) dopamine (da) levels in the adult brain. |
2007-05-22 |
2023-08-12 |
Not clear |
| Susumu Koyama, Mark S Brodie, Sarah B Appe. Ethanol inhibition of m-current and ethanol-induced direct excitation of ventral tegmental area dopamine neurons. Journal of neurophysiology. vol 97. issue 3. 2007-05-21. PMID:16956995. |
ethanol inhibition of m-current and ethanol-induced direct excitation of ventral tegmental area dopamine neurons. |
2007-05-21 |
2023-08-12 |
Not clear |
| Susumu Koyama, Mark S Brodie, Sarah B Appe. Ethanol inhibition of m-current and ethanol-induced direct excitation of ventral tegmental area dopamine neurons. Journal of neurophysiology. vol 97. issue 3. 2007-05-21. PMID:16956995. |
ethanol-induced excitation of ventral tegmental area dopamine (da vta) neurons is thought to be critical for the reinforcing effects of ethanol. |
2007-05-21 |
2023-08-12 |
Not clear |
| Robin L Williard, Lawrence D Middaugh, Hao-Jie B Zhu, Kennerly S Patric. Methylphenidate and its ethanol transesterification metabolite ethylphenidate: brain disposition, monoamine transporters and motor activity. Behavioural pharmacology. vol 18. issue 1. 2007-05-02. PMID:17218796. |
experimental results were that: (a) coadministration of ethanol with the separate methylphenidate isomers enantioselectively produced l-ethylphenidate; (b) d and dl-forms of methylphenidate and ethylphenidate produced dose-responsive increases in motor activity with stimulation being less for ethylphenidate; (c) plasma and whole-brain concentrations were greater for ethylphenidate than methylphenidate and (d) d and dl-methylphenidate and ethylphenidate exhibited comparably potent low inhibition of the dopamine transporter, whereas ethylphenidate was a less potent norepinephrine transporter inhibitor. |
2007-05-02 |
2023-08-12 |
mouse |
| Anne M Landau, Edouard Kouassi, Rosmarie Siegrist-Johnstone, Julie Desbarat. Proteasome inhibitor model of Parkinson's disease in mice is confounded by neurotoxicity of the ethanol vehicle. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 3. 2007-05-01. PMID:17230468. |
administration of ethanol alone led to significant long-term alterations in dopamine levels. |
2007-05-01 |
2023-08-12 |
mouse |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
ethanol-induced accumbal dopamine elevations have been linked to ethanol consumption. |
2007-04-04 |
2023-08-12 |
rat |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
it is unclear, however, where along the mesolimbic dopamine system this effect is initiated and why the ethanol-induced dopamine elevations are transient, returning to pre-drug baseline before brain and blood ethanol levels decline. |
2007-04-04 |
2023-08-12 |
rat |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
using in vivo microdialysis, experiment 1 investigated the effect of local ethanol application in the nucleus accumbens, the ventral tegmental area and the nucleus accumbens+the ventral tegmental area, on accumbal dopamine. |
2007-04-04 |
2023-08-12 |
rat |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
experiment 2 examined whether the rapid withdrawal of dopamine response to ethanol involves activation of gaba(a)-receptors, by analyzing the effect of accumbal co-perfusion of picrotoxin and ethanol. |
2007-04-04 |
2023-08-12 |
rat |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
in experiment 1, ethanol perfusion into the ventral tegmental area alone did not affect accumbal dopamine. |
2007-04-04 |
2023-08-12 |
rat |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
ethanol co-perfusion of one of the tested doses into the ventral tegmental+the nucleus accumbens produced higher dopamine levels than ethanol perfusion into the nucleus accumbens alone during 120-160 min following perfusion onset. |
2007-04-04 |
2023-08-12 |
rat |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
in experiment 2, accumbal ethanol perfusion caused a transient increase in nucleus accumbens dopamine. |
2007-04-04 |
2023-08-12 |
rat |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
co-perfusion of ethanol and picrotoxin produced a sustained dopamine elevation. |
2007-04-04 |
2023-08-12 |
rat |