| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wanda Dyr, Janusz Ligieza, Wojciech Kostowsk. The effect of cannabinoid CB(1) receptor antagonist rimonabant (SR-141716) on ethanol drinking in high-preferring rats. Alcohol (Fayetteville, N.Y.). vol 42. issue 6. 2008-10-16. PMID:18504086. |
our result extends the suppressive effect of cannabinoid cb(1) receptor antagonist to the ethanol drinking behavior in warsaw high-preferring line of rats. |
2008-10-16 |
2023-08-12 |
rat |
| Wanda Dyr, Janusz Ligieza, Wojciech Kostowsk. The effect of cannabinoid CB(1) receptor antagonist rimonabant (SR-141716) on ethanol drinking in high-preferring rats. Alcohol (Fayetteville, N.Y.). vol 42. issue 6. 2008-10-16. PMID:18504086. |
the result also supports a growing body of literature indicating that the cannabinoid cb(1) receptor is involved in motivational and appetitive properties of ethanol. |
2008-10-16 |
2023-08-12 |
rat |
| Henrik H Hansen, Birte Krutz, Marco Sifringer, Vanya Stefovska, Petra Bittigau, Fritz Pragst, Giovanni Marsicano, Beat Lutz, Chrysanthy Ikonomido. Cannabinoids enhance susceptibility of immature brain to ethanol neurotoxicity. Annals of neurology. vol 64. issue 1. 2008-09-04. PMID:18067175. |
cannabinoids enhance susceptibility of immature brain to ethanol neurotoxicity. |
2008-09-04 |
2023-08-12 |
Not clear |
| José M Oliva, Sergio Ortiz, Sandra Pérez-Rial, Jorge Manzanare. Time dependent alterations on tyrosine hydroxylase, opioid and cannabinoid CB1 receptor gene expressions after acute ethanol administration in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 5. 2008-07-02. PMID:17964122. |
time dependent alterations on tyrosine hydroxylase, opioid and cannabinoid cb1 receptor gene expressions after acute ethanol administration in the rat brain. |
2008-07-02 |
2023-08-12 |
rat |
| José M Oliva, Sergio Ortiz, Sandra Pérez-Rial, Jorge Manzanare. Time dependent alterations on tyrosine hydroxylase, opioid and cannabinoid CB1 receptor gene expressions after acute ethanol administration in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 5. 2008-07-02. PMID:17964122. |
the aim of this study was to examine the differential regulation after acute ethanol administration on tyrosine hydroxylase, proenkephalin and cannabinoid cb(1) receptor gene expressions in selected areas of the rat brain. |
2008-07-02 |
2023-08-12 |
rat |
| José M Oliva, Sergio Ortiz, Sandra Pérez-Rial, Jorge Manzanare. Time dependent alterations on tyrosine hydroxylase, opioid and cannabinoid CB1 receptor gene expressions after acute ethanol administration in the rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 18. issue 5. 2008-07-02. PMID:17964122. |
in conclusion, the results suggest that an acute dose of ethanol induces neuroplastic alterations in proenkephalin, tyrosine hydroxylase and cannabinoid cb1 receptor gene expressions that may contribute to trigger the rewarding effects of ethanol consumption. |
2008-07-02 |
2023-08-12 |
rat |
| Scott L Friedman, Natalia Niet. Cannabinoids provoke alcoholic steatosis through a conspiracy of neighbors. Cell metabolism. vol 7. issue 3. 2008-04-29. PMID:18316020. |
a report in this issue of cell metabolism (jeong et al., 2008) now links hepatic stellate cells, a resident liver fibrogenic cell type, to the generation of steatosis through production of the endocannabinoid 2-arachidonoylglycerol (2-ag) after ethanol feeding, leading to paracrine stimulation of hepatocyte cb1 receptors. |
2008-04-29 |
2023-08-12 |
Not clear |
| Won-il Jeong, Douglas Osei-Hyiaman, Ogyi Park, Jie Liu, Sándor Bátkai, Partha Mukhopadhyay, Norio Horiguchi, Judith Harvey-White, Giovanni Marsicano, Beat Lutz, Bin Gao, George Kuno. Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell metabolism. vol 7. issue 3. 2008-04-29. PMID:18316028. |
here we report that the steatosis induced in mice by a low-fat, liquid ethanol diet is attenuated by concurrent blockade of cannabinoid cb1 receptors. |
2008-04-29 |
2023-08-12 |
mouse |
| Won-il Jeong, Douglas Osei-Hyiaman, Ogyi Park, Jie Liu, Sándor Bátkai, Partha Mukhopadhyay, Norio Horiguchi, Judith Harvey-White, Giovanni Marsicano, Beat Lutz, Bin Gao, George Kuno. Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell metabolism. vol 7. issue 3. 2008-04-29. PMID:18316028. |
ethanol feeding increases the hepatic expression of cb1 receptors and upregulates the endocannabinoid 2-arachidonoylglycerol (2-ag) and its biosynthetic enzyme diacylglycerol lipase beta selectively in hepatic stellate cells. |
2008-04-29 |
2023-08-12 |
mouse |
| G Biala, B Budzynsk. Calcium-dependent mechanisms of the reinstatement of nicotine-conditioned place preference by drug priming in rats. Pharmacology, biochemistry, and behavior. vol 89. issue 1. 2008-04-09. PMID:18178244. |
as reinstatement of drug-seeking is a factor for the development of dependence, the l-type calcium channel antagonists may be useful in the relapse-prevention phase of addiction treatment, including cannabinoid, ethanol, and/or nicotine dependence. |
2008-04-09 |
2023-08-12 |
rat |
| Valeria Rettori, Javier Fernandez-Solari, Juan P Prestifilippo, Claudia Mohn, Andrea De Laurentiis, Stefan R Bornstein, Monika Ehrhart-Bornstein, Juan C Elverdin, Samuel M McCan. Endocannabinoids in TNF-alpha and ethanol actions. Neuroimmunomodulation. vol 14. issue 3-4. 2008-03-31. PMID:18073513. |
during inflammation, this activation of the endocannabinoid system seems to be mediated by an increase in tnf-alpha production followed by anandamide augmentations, similarly the effect of intragastric administration of ethanol (3 g/kg) seems to be due to an increase in anandamide. |
2008-03-31 |
2023-08-12 |
rat |
| Mindy J Hull, Matthew Juhascik, Frank Mazur, Mark A Flomenbaum, George S Behonic. Fatalities associated with fentanyl and co-administered cocaine or opiates. Journal of forensic sciences. vol 52. issue 6. 2008-02-28. PMID:17944902. |
ethanol, cannabinoids, diazepam, citalopram, and diphenhydramine were each detected in greater than 10% of the licit fentanyl cases. |
2008-02-28 |
2023-08-12 |
Not clear |
| Laurence Labat, Bernard Fontaine, Chantal Delzenne, Anne Doublet, Marie Christine Marek, Dominique Tellier, Murielle Tonneau, Michel Lhermitte, Paul Frima. Prevalence of psychoactive substances in truck drivers in the Nord-Pas-de-Calais region (France). Forensic science international. vol 174. issue 2-3. 2008-02-05. PMID:17418990. |
all these results confirm those of the previous study for cannabinoids and ethanol in safety/security workstations. |
2008-02-05 |
2023-08-12 |
Not clear |
| Shashank R Josh. Endocannabinoid system--a novel target for cardiometabolic risk. The Journal of the Association of Physicians of India. vol 55. 2007-12-20. PMID:17879500. |
therefore attenuation of the activity of the ec system would have therapeutic benefit in treating disorders that might have a component of excess appetite drive or over-activity of the endocannabinoid system, such as obesity, ethanol and other drug abuse, and a variety of central nervous system and other disorders. |
2007-12-20 |
2023-08-12 |
Not clear |
| Andrea Cippitelli, Ainhoa Bilbao, Miguel Angel Gorriti, Miguel Navarro, Maurizio Massi, Daniele Piomelli, Roberto Ciccocioppo, Fernando Rodríguez de Fonsec. The anandamide transport inhibitor AM404 reduces ethanol self-administration. The European journal of neuroscience. vol 26. issue 2. 2007-10-25. PMID:17650118. |
the endocannabinoid system mediates in the pharmacological actions of ethanol and genetic studies link endocannabinoid signaling to alcoholism. |
2007-10-25 |
2023-08-12 |
rat |
| Andrea Cippitelli, Ainhoa Bilbao, Miguel Angel Gorriti, Miguel Navarro, Maurizio Massi, Daniele Piomelli, Roberto Ciccocioppo, Fernando Rodríguez de Fonsec. The anandamide transport inhibitor AM404 reduces ethanol self-administration. The European journal of neuroscience. vol 26. issue 2. 2007-10-25. PMID:17650118. |
the mechanism of action of am404 does not involve cannabinoid cb1 receptors as the cb1-selective antagonist sr141716a did not block the reduction of ethanol self-administration induced by the anandamide uptake blocker. |
2007-10-25 |
2023-08-12 |
rat |
| Daina Economidou, Laura Mattioli, Massimo Ubaldi, Anbarasu Lourdusamy, Laura Soverchia, Gary Hardiman, Patrizia Campolongo, Vincenzo Cuomo, Roberto Ciccociopp. Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol seeking in rat adult offspring following perinatal exposure to Delta9-tetrahydrocannabinol. Toxicology and applied pharmacology. vol 223. issue 1. 2007-09-27. PMID:17618662. |
furthermore, the effect of the selective cannabinoid cb(1) receptor antagonist, sr-141716a, on ethanol self-administration and on reinstatement of ethanol-seeking behavior induced either by stress or conditioned drug-paired cues was evaluated in adult offspring of rats exposed to the same perinatal treatment. |
2007-09-27 |
2023-08-12 |
rat |
| Daina Economidou, Laura Mattioli, Massimo Ubaldi, Anbarasu Lourdusamy, Laura Soverchia, Gary Hardiman, Patrizia Campolongo, Vincenzo Cuomo, Roberto Ciccociopp. Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol seeking in rat adult offspring following perinatal exposure to Delta9-tetrahydrocannabinol. Toxicology and applied pharmacology. vol 223. issue 1. 2007-09-27. PMID:17618662. |
on the other hand, the results obtained with sr-141716a emphasize that endocannabinoid mechanisms play a major role in ethanol self-administration, as well as in the reinstatement of ethanol-seeking behavior induced by conditioned cues, supporting the idea that cannabinoid cb(1) receptor antagonists may represent interesting agents for the pharmacotherapy of alcoholism. |
2007-09-27 |
2023-08-12 |
rat |
| S Xie, M A Furjanic, J J Ferrara, N R McAndrew, E L Ardino, A Ngondara, Y Bernstein, K J Thomas, E Kim, J M Walker, S Nagar, S J Ward, R B Raff. The endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB1 receptor antagonism--or inverse agonism--as potential obesity treatment and other therapeutic use. Journal of clinical pharmacy and therapeutics. vol 32. issue 3. 2007-09-20. PMID:17489873. |
it is therefore reasonable to hypothesize that the attenuation of the activity of this system would have therapeutic benefit in treating disorders that might have a component of excess appetitive drive or over-activity of the endocannabinoid system, such as obesity, ethanol and other drug abuse, and a variety of central nervous system and other disorders. |
2007-09-20 |
2023-08-12 |
Not clear |
| Yuri A Blednov, Benjamin F Cravatt, Stephen L Boehm, Danielle Walker, R Adron Harri. Role of endocannabinoids in alcohol consumption and intoxication: studies of mice lacking fatty acid amide hydrolase. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 7. 2007-08-31. PMID:17164820. |
endocannabinoid signaling plays the important role in regulation of ethanol intake. |
2007-08-31 |
2023-08-12 |
mouse |