| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peer K Lilleng, Lars Ivar Mehlum, Liliana Bachs, Inge Moril. Deaths after intravenous misuse of transdermal fentanyl. Journal of forensic sciences. vol 49. issue 6. 2005-01-21. PMID:15568716. |
in the first case, the toxicological analysis revealed fentanyl (2.7 ng/ml), morphine (31.4 ng/ml), and ethanol (1.1 g/l) in postmortem blood and amphetamine, cannabinoids, morphine, and ethanol (1.4 g/l) in postmortem urine. |
2005-01-21 |
2023-08-12 |
Not clear |
| Audra L Stinchcomb, Satyanarayana Valiveti, Dana C Hammell, Diana R Ramse. Human skin permeation of Delta8-tetrahydrocannabinol, cannabidiol and cannabinol. The Journal of pharmacy and pharmacology. vol 56. issue 3. 2004-07-20. PMID:15025853. |
combinations of these cannabinoids with ethanol will be further studied in transdermal patch formulations in vitro and in vivo, as significant flux levels of all the drugs were obtained. |
2004-07-20 |
2023-08-12 |
human |
| Sergio Ortiz, José M Oliva, Sandra Pérez-Rial, Tomás Palomo, Jorge Manzanare. Chronic ethanol consumption regulates cannabinoid CB1 receptor gene expression in selected regions of rat brain. Alcohol and alcoholism (Oxford, Oxfordshire). vol 39. issue 2. 2004-06-28. PMID:14998822. |
chronic ethanol consumption regulates cannabinoid cb1 receptor gene expression in selected regions of rat brain. |
2004-06-28 |
2023-08-12 |
rat |
| Sergio Ortiz, José M Oliva, Sandra Pérez-Rial, Tomás Palomo, Jorge Manzanare. Chronic ethanol consumption regulates cannabinoid CB1 receptor gene expression in selected regions of rat brain. Alcohol and alcoholism (Oxford, Oxfordshire). vol 39. issue 2. 2004-06-28. PMID:14998822. |
the aim of this study was to examine the effects of chronic ethanol consumption in cannabinoid cb(1) receptor gene expression in wistar rats. |
2004-06-28 |
2023-08-12 |
rat |
| Javier Fernández-Solari, Camila Scorticati, Claudia Mohn, Andrea De Laurentiis, Silvia Billi, Ana Franchi, Samuel M McCann, Valeria Rettor. Alcohol inhibits luteinizing hormone-releasing hormone release by activating the endocannabinoid system. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 9. 2004-06-17. PMID:14981261. |
we hypothesized that ethanol (etoh) might act through the endocannabinoid system to inhibit luteinizing hormone-releasing hormone (lhrh) release. |
2004-06-17 |
2023-08-12 |
Not clear |
| Mickaël Naassila, Olivier Pierrefiche, Catherine Ledent, Martine Daous. Decreased alcohol self-administration and increased alcohol sensitivity and withdrawal in CB1 receptor knockout mice. Neuropharmacology. vol 46. issue 2. 2004-05-28. PMID:14680762. |
recent advances in the understanding of the neurobiological basis of alcohol dependence suggest that the endocannabinoid system may play a key role in the reinforcing effects of ethanol. |
2004-05-28 |
2023-08-12 |
mouse |
| Balapal S Basavarajappa, Mariko Saito, Thomas B Cooper, Basalingappa L Hungun. Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons. European journal of pharmacology. vol 466. issue 1-2. 2004-03-08. PMID:12679143. |
anandamide transport processes are independent of cannabinoid cb1 receptor, as cannabinoid cb1 receptor knockout mice exhibited time-dependent anandamide transport and cannabinoid cb1 receptor antagonists did not alter the effects of chronic ethanol on anandamide transport. |
2004-03-08 |
2023-08-12 |
mouse |
| Frank Musshoff, Dirk W Lachenmeier, Burkhard Made. Methadone substitution: medicolegal problems in Germany. Forensic science international. vol 133. issue 1-2. 2003-07-29. PMID:12742698. |
in most of the cases, up to five additional drugs were also being taken: benzodiazepines (61%), ethanol (40%), morphine (39%), cannabinoids (35%), cocaine (28%), anti-depressants (3%), and amphetamines (2%). |
2003-07-29 |
2023-08-12 |
Not clear |
| Ildiko Racz, Andras Bilkei-Gorzo, Zsuzsanna E Toth, Kerstin Michel, Miklós Palkovits, Andreas Zimme. A critical role for the cannabinoid CB1 receptors in alcohol dependence and stress-stimulated ethanol drinking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 6. 2003-04-17. PMID:12657705. |
a critical role for the cannabinoid cb1 receptors in alcohol dependence and stress-stimulated ethanol drinking. |
2003-04-17 |
2023-08-12 |
mouse |
| Ildiko Racz, Andras Bilkei-Gorzo, Zsuzsanna E Toth, Kerstin Michel, Miklós Palkovits, Andreas Zimme. A critical role for the cannabinoid CB1 receptors in alcohol dependence and stress-stimulated ethanol drinking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 6. 2003-04-17. PMID:12657705. |
here we show that ethanol withdrawal symptoms were completely absent in cannabinoid cb1 receptor-deficient mice, although acute effects of ethanol and ethanol tolerance and preference were basically normal. |
2003-04-17 |
2023-08-12 |
mouse |
| Cory S Freedland, Christopher T Whitlow, Hilary R Smith, Linda J Porrin. Functional consequences of the acute administration of the cannabinoid receptor antagonist, SR141716A, in cannabinoid-naive and -tolerant animals: a quantitative 2-[14C]deoxyglucose study. Brain research. vol 962. issue 1-2. 2003-04-01. PMID:12543468. |
administration of the cannabinoid antagonist, sr141716a, markedly reduces intake of sucrose solutions, food pellets, and ethanol. |
2003-04-01 |
2023-08-12 |
rat |
| Lei Wang, Jie Liu, Judith Harvey-White, Andreas Zimmer, George Kuno. Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 3. 2003-03-18. PMID:12538878. |
endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice. |
2003-03-18 |
2023-08-12 |
mouse |
| Lei Wang, Jie Liu, Judith Harvey-White, Andreas Zimmer, George Kuno. Endocannabinoid signaling via cannabinoid receptor 1 is involved in ethanol preference and its age-dependent decline in mice. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 3. 2003-03-18. PMID:12538878. |
cannabinoids and ethanol can activate the same reward pathways, which could suggest endocannabinoid involvement in the rewarding effects of ethanol. |
2003-03-18 |
2023-08-12 |
mouse |
| Roberto Ciccocioppo, Lorena Antonelli, Michela Biondini, Marina Perfumi, Pierluigi Pompei, Maurizio Mass. Memory impairment following combined exposure to delta(9)-tetrahydrocannabinol and ethanol in rats. European journal of pharmacology. vol 449. issue 3. 2003-02-13. PMID:12167466. |
since both ethanol and cannabinoids are known to impair learning and memory, the present study investigated in rats the effects of combined exposure to ethanol and delta(9)-tetrahydrocannabinol (thc) in a memory task, the object recognition test. |
2003-02-13 |
2023-08-12 |
rat |
| Sara González, Maria Grazia Cascio, Javier Fernández-Ruiz, Filomena Fezza, Vincenzo Di Marzo, José A Ramo. Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393235. |
changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. |
2003-01-24 |
2023-08-12 |
rat |
| Sara González, Maria Grazia Cascio, Javier Fernández-Ruiz, Filomena Fezza, Vincenzo Di Marzo, José A Ramo. Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393235. |
in the present study, we have extended this objective by examining changes in the brain contents of arachidonoylethanolamide (aea) and 2-arachidonoyl-glycerol (2-ag), the endogenous ligands for cannabinoid receptors, in animals chronically exposed to cocaine, nicotine or ethanol. |
2003-01-24 |
2023-08-12 |
rat |
| E Frid. Endocannabinoids in the central nervous system--an overview. Prostaglandins, leukotrienes, and essential fatty acids. vol 66. issue 2-3. 2002-12-06. PMID:12052038. |
many aspects of the physiology and pharmacology of anandamide (arachidonoyl ethanol amide), the first endogenous cannabinoid ligand ("endocannabinoid") isolated from pig brain, have been studied since its discovery in 1992. |
2002-12-06 |
2023-08-12 |
Not clear |
| B S Basavarajappa, B L Hungun. Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview. Prostaglandins, leukotrienes, and essential fatty acids. vol 66. issue 2-3. 2002-12-06. PMID:12052043. |
the current review evaluates the evidence that some of the pharmacological and behavioral effects of ethanol (etoh), including etoh-preferring behavior, may be mediated through the endocannabinoid signaling system. |
2002-12-06 |
2023-08-12 |
mouse |
| Basalingappa L Hungund, Balapal S Basavarajappa, Csaba Vadasz, George Kunos, Fernando Rodriguez de Fonseca, Giancarlo Colombo, Salvatore Serra, Loren Parsons, George F Koo. Ethanol, endocannabinoids, and the cannabinoidergic signaling system. Alcoholism, clinical and experimental research. vol 26. issue 4. 2002-08-16. PMID:11981134. |
the presentations were (1) role of endocannabinoids in ethanol tolerance, by appa hungund; (2) modulation of cannabinoid receptor and its signal transduction in chronic alcoholism, by b. s. basavarajappa; (3) endocannabinoid involvement in the control of appetitive behavior, by george kunos; (4) regulation of voluntary ethanol intake by cannabinoid receptor agonists and antagonists in alcohol-preferring sp rats, by giancarlo colombo; (5) role of endogenous cannabinoid system in alcoholism, by fernado rodriguez de fonseca; and (6) endocannabinoids and dopamine interactions in vivo, by loren parsons and george koob. |
2002-08-16 |
2023-08-12 |
rat |
| Sara Gonzalez, Javier Fernandez-Ruiz, Valentina Sparpaglione, Daniela Parolaro, Jose A Ramo. Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levels. Drug and alcohol dependence. vol 66. issue 1. 2002-05-16. PMID:11850139. |
chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid cb(1) receptor binding and mrna levels. |
2002-05-16 |
2023-08-12 |
rat |