| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Louise Adermark, Susanne Jonsson, Mia Ericson, Bo Söderpal. Intermittent ethanol consumption depresses endocannabinoid-signaling in the dorsolateral striatum of rat. Neuropharmacology. vol 61. issue 7. 2012-01-27. PMID:21251919. |
in this study, endocannabinoid (ecb) signaling in the dorsolateral striatum, a brain region vital for habit formation, was evaluated in acutely isolated brain slices from ethanol (etoh)-consuming rats and control rats. |
2012-01-27 |
2023-08-12 |
rat |
| Cristian Palmiere, Christophe Brunel, Frank Sporkert, Marc Augsburge. An unusual case of accidental poisoning: fatal methadone inhalation. Journal of forensic sciences. vol 56. issue 4. 2011-12-19. PMID:21361950. |
the toxicological analyses performed on blood and urine taken at the hospital revealed methadone, cannabinoids, and ethanol. |
2011-12-19 |
2023-08-12 |
Not clear |
| Matthias Klugmann, Viktoria Klippenstein, F Markus Leweke, Rainer Spanagel, Miriam Schneide. Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. The international journal of neuropsychopharmacology. vol 14. issue 4. 2011-12-16. PMID:21211107. |
cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and nmda receptor associated protein levels. |
2011-12-16 |
2023-08-12 |
rat |
| Matthias Klugmann, Viktoria Klippenstein, F Markus Leweke, Rainer Spanagel, Miriam Schneide. Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. The international journal of neuropsychopharmacology. vol 14. issue 4. 2011-12-16. PMID:21211107. |
recent evidence suggests an involvement of the endocannabinoid system in the regulation of emotional behaviour and ethanol intake. |
2011-12-16 |
2023-08-12 |
rat |
| Matthias Klugmann, Viktoria Klippenstein, F Markus Leweke, Rainer Spanagel, Miriam Schneide. Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. The international journal of neuropsychopharmacology. vol 14. issue 4. 2011-12-16. PMID:21211107. |
additionally, increased intake of higher ethanol solutions after cannabinoid treatment was only observed in pubertal rats. |
2011-12-16 |
2023-08-12 |
rat |
| S V Siegmun. Role of the endocannabinoid system in alcoholic liver disease. Digestive diseases (Basel, Switzerland). vol 28. issue 6. 2011-08-24. PMID:21525760. |
moreover, ethanol feeding upregulated the endocannabinoid 2-arachidonoyl glycerol and its biosynthetic enzyme diacylglycerol lipase-β selectively in hepatic stellate cells and subsequently increased expression of cb1 receptors in hepatocytes of wild-type mice leading to cb1-dependent hepatic steatosis by activation of lipogenic pathways. |
2011-08-24 |
2023-08-12 |
mouse |
| Marko Lehtonen, Markus Storvik, Hanna Malinen, Petri Hyytiä, Merja Lakso, Seppo Auriola, Garry Wong, James C Callawa. Determination of endocannabinoids in nematodes and human brain tissue by liquid chromatography electrospray ionization tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 879. issue 11-12. 2011-07-21. PMID:21367677. |
a simple and highly sensitive liquid chromatography/tandem mass spectrometric (lc/ms/ms) method was developed to compare endogenous cannabinoid levels in nematodes and in brains of rats and humans, with and without prior exposure to ethanol. |
2011-07-21 |
2023-08-12 |
rat |
| Stefan W Toennes, Kirsten Schneider, Gerold F Kauert, Cora Wunder, Manfred R Moeller, Eef L Theunissen, Johannes G Ramaeker. Influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users. Analytical and bioanalytical chemistry. vol 400. issue 1. 2011-06-27. PMID:21116612. |
influence of ethanol on cannabinoid pharmacokinetic parameters in chronic users. |
2011-06-27 |
2023-08-12 |
human |
| Panayotis K Thanos, Vanessa Gopez, Foteini Delis, Michael Michaelides, David K Grandy, Gene-Jack Wang, George Kunos, Nora D Volko. Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. Alcoholism, clinical and experimental research. vol 35. issue 1. 2011-06-23. PMID:20958329. |
upregulation of cannabinoid type 1 receptors in dopamine d2 receptor knockout mice is reversed by chronic forced ethanol consumption. |
2011-06-23 |
2023-08-12 |
mouse |
| Panayotis K Thanos, Vanessa Gopez, Foteini Delis, Michael Michaelides, David K Grandy, Gene-Jack Wang, George Kunos, Nora D Volko. Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption. Alcoholism, clinical and experimental research. vol 35. issue 1. 2011-06-23. PMID:20958329. |
the anatomical proximity of the cannabinoid type 1 (cnr1/cb1r) and the dopamine d2 receptors (drd2), their ability to form cb1r-drd2 heteromers, their opposing roles in locomotion, and their involvement in ethanol's reinforcing and addictive properties prompted us to study the levels and distribution of cb1r after chronic ethanol intake, in the presence and absence of drd2. |
2011-06-23 |
2023-08-12 |
mouse |
| Rosana Camarini, Ricardo Marcos Pautassi, Milagros Méndez, Isabel Marian Quadros, Maria Lucia Souza-Formigoni, Roseli Boerngen-Lacerd. Behavioral and neurochemical studies in distinct animal models of ethanol's motivational effects. Current drug abuse reviews. vol 3. issue 4. 2011-06-13. PMID:21208169. |
ethanol interacts with several neurotransmitter (dopaminergic, glutamatergic, opioidergic and cannabinoid) and neuromodulators and these interactions are involved in the development and maintenance of alcohol self-administration. |
2011-06-13 |
2023-08-12 |
Not clear |
| Daniela Parolaro, Daniela Vigano, Natalia Realini, Tiziana Rubin. Role of endocannabinoids in regulating drug dependence. Neuropsychiatric disease and treatment. vol 3. issue 6. 2011-05-17. PMID:19300605. |
experimental models are providing increasing evidence for the pharmacological management of endocannabinoid signaling not only to block the direct reinforcing effects of cannabis, opioids, nicotine and ethanol, but also for preventing relapse to the various drugs of abuse, including opioids, cocaine, nicotine, alcohol and metamphetamine. |
2011-05-17 |
2023-08-12 |
Not clear |
| N M W J de Bruin, J H M Lange, C G Kruse, A H Herremans, A N M Schoffelmeer, M van Drimmelen, T J De Vrie. SLV330, a cannabinoid CB(1) receptor antagonist, attenuates ethanol and nicotine seeking and improves inhibitory response control in rats. Behavioural brain research. vol 217. issue 2. 2011-04-18. PMID:21074574. |
slv330, a cannabinoid cb(1) receptor antagonist, attenuates ethanol and nicotine seeking and improves inhibitory response control in rats. |
2011-04-18 |
2023-08-12 |
rat |
| Grażyna Biała, Barbara Budzyńsk. Rimonabant attenuates sensitization, cross-sensitization and cross-reinstatement of place preference induced by nicotine and ethanol. Pharmacological reports : PR. vol 62. issue 5. 2011-04-13. PMID:21098863. |
finally, when we examined the influence of rimonabant (0.5, 1 and 2 mg/kg, ip), we found that this cannabinoid cb₁ receptor antagonist attenuated reinstatement effect of ethanol priming as well as nicotine sensitization and locomotor cross-sensitization between nicotine and ethanol. |
2011-04-13 |
2023-08-12 |
mouse |
| Grażyna Biała, Barbara Budzyńsk. Rimonabant attenuates sensitization, cross-sensitization and cross-reinstatement of place preference induced by nicotine and ethanol. Pharmacological reports : PR. vol 62. issue 5. 2011-04-13. PMID:21098863. |
our results indicate that similar endocannabinoid-dependent mechanisms re involved in the locomotor stimulant and reinforcing effects of nicotine and ethanol in rodents, and as such these data may provide further evidence for the use of cannabinoid cb₁ receptor antagonists in treatment of tobacco addiction with or without concomitant ethanol dependence. |
2011-04-13 |
2023-08-12 |
mouse |
| Sarit Shor, Irena Nulman, Vivian Kulaga, Gideon Kore. Heavy in utero ethanol exposure is associated with the use of other drugs of abuse in a high-risk population. Alcohol (Fayetteville, N.Y.). vol 44. issue 7-8. 2011-03-11. PMID:20031369. |
exposure to cannabinoids predicted less likely exposure to ethanol (or=0.61; 95% ci: 0.38-0.98) and no significant difference was noted in the exposure to cocaine (or=1.24, 95% ci: 0.81-1.91). |
2011-03-11 |
2023-08-12 |
Not clear |
| Marisa Roberto, Maureen Cruz, Michal Bajo, George R Siggins, Loren H Parsons, Paul Schweitze. The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 9. 2010-10-28. PMID:20463657. |
the endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala. |
2010-10-28 |
2023-08-12 |
Not clear |
| Marisa Roberto, Maureen Cruz, Michal Bajo, George R Siggins, Loren H Parsons, Paul Schweitze. The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 9. 2010-10-28. PMID:20463657. |
the central amygdala (cea) has a major role in alcohol dependence and reinforcement, and behavioral and neurochemical evidence suggests a role for the endocannabinoid (ecb) system in ethanol binging and dependence. |
2010-10-28 |
2023-08-12 |
Not clear |
| Marisa Roberto, Maureen Cruz, Michal Bajo, George R Siggins, Loren H Parsons, Paul Schweitze. The endocannabinoid system tonically regulates inhibitory transmission and depresses the effect of ethanol in central amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 9. 2010-10-28. PMID:20463657. |
we used a slice preparation to investigate the physiological role of cannabinoids and their interaction with ethanol on inhibitory synaptic transmission in cea. |
2010-10-28 |
2023-08-12 |
Not clear |
| Antonio Armari. Activation of the hypothalamic-pituitary-adrenal axis by addictive drugs: different pathways, common outcome. Trends in pharmacological sciences. vol 31. issue 7. 2010-10-07. PMID:20537734. |
addictive drugs (opiates, ethanol, cannabinoids (cbs), nicotine, cocaine, amphetamines) induce activation of the hypothalamic-pituitary-adrenal (hpa) axis, with the subsequent release of adrenocorticotropic hormone and glucocorticoids. |
2010-10-07 |
2023-08-12 |
Not clear |