| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vishnudutt Purohit, Rao Rapaka, David Shurtlef. Role of cannabinoids in the development of fatty liver (steatosis). The AAPS journal. vol 12. issue 2. 2010-06-15. PMID:20204561. |
steatogenic agents such as ethanol and high-fat diet can upregulate the activity of cannabinoid 1 (cb1) receptors via increasing synthesis of endocannabinoids, 2-arachidonoylglycerol, and anandamide. |
2010-06-15 |
2023-08-12 |
Not clear |
| D N Linsenbardt, S L Boeh. Agonism of the endocannabinoid system modulates binge-like alcohol intake in male C57BL/6J mice: involvement of the posterior ventral tegmental area. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19665522. |
recent studies have indicated a role for the endocannabinoid system in the behavioral and physiological effects of alcohol (ethanol), particularly ethanol seeking behaviors. |
2010-02-12 |
2023-08-12 |
mouse |
| D N Linsenbardt, S L Boeh. Agonism of the endocannabinoid system modulates binge-like alcohol intake in male C57BL/6J mice: involvement of the posterior ventral tegmental area. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19665522. |
the current study used a newly developed strain-specific animal model of binge drinking, dubbed 'drinking in the dark' (did), to determine if facilitation of the endocannabinoid system with the synthetic cannabinoid agonist win 55-212,2 (win) modulates binge-like ethanol intake in male c57bl/6j (b6) mice. |
2010-02-12 |
2023-08-12 |
mouse |
| D N Linsenbardt, S L Boeh. Agonism of the endocannabinoid system modulates binge-like alcohol intake in male C57BL/6J mice: involvement of the posterior ventral tegmental area. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19665522. |
manipulations, and evidence in support of the involvement of subregions of the ventral tegmental area (vta) in governing self-administration of ethanol (rodd-henricks et al., (2000) psychopharmacology (berl) 149(3):217-224) as well as binge-like intake using the did model (moore & boehm, (2009 behav neurosci 123(3):555-563), we extended these findings to evaluate the role of the endocannabinoid system within the anterior and posterior sub regions of the vta using site-specific microinjections. |
2010-02-12 |
2023-08-12 |
mouse |
| D N Linsenbardt, S L Boeh. Agonism of the endocannabinoid system modulates binge-like alcohol intake in male C57BL/6J mice: involvement of the posterior ventral tegmental area. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19665522. |
the present data are consistent with previous research in that agonism of the endocannabinoid system increases ethanol intake in rodents and implicate the pvta in the modulation of drinking to intoxication. |
2010-02-12 |
2023-08-12 |
mouse |
| Viviana Trezza, Petra J J Baarendse, Louk J M J Vanderschure. Prosocial effects of nicotine and ethanol in adolescent rats through partially dissociable neurobehavioral mechanisms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 12. 2010-01-12. PMID:19657330. |
social play behavior is rewarding, and it is modulated through opioid, cannabinoid and dopaminergic neurotransmission, which are also involved in the reinforcing properties of nicotine and ethanol. |
2010-01-12 |
2023-08-12 |
rat |
| Sunita Bava, Lawrence R Frank, Tim McQueeny, Brian C Schweinsburg, Alecia D Schweinsburg, Susan F Taper. Altered white matter microstructure in adolescent substance users. Psychiatry research. vol 173. issue 3. 2009-10-20. PMID:19699064. |
building on evidence that cannabinoid receptors are present in myelin precursors and affect glial cell processing, and that excessive ethanol exposure is associated with persistently impaired myelination, we used diffusion tensor imaging (dti) to characterize white matter integrity in heavy substance using and non-using adolescents. |
2009-10-20 |
2023-08-12 |
Not clear |
| Lily Alvarez-Jaimes, David G Stouffer, Loren H Parson. Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. Journal of neurochemistry. vol 111. issue 1. 2009-10-09. PMID:19650871. |
chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. |
2009-10-09 |
2023-08-12 |
rat |
| Lily Alvarez-Jaimes, David G Stouffer, Loren H Parson. Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. Journal of neurochemistry. vol 111. issue 1. 2009-10-09. PMID:19650871. |
we employed in vivo microdialysis to characterize the effect of an ethanol challenge injection on endocannabinoid levels in the nucleus accumbens of ethanol-naïve and chronic ethanol-treated rats. |
2009-10-09 |
2023-08-12 |
rat |
| Lily Alvarez-Jaimes, David G Stouffer, Loren H Parson. Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. Journal of neurochemistry. vol 111. issue 1. 2009-10-09. PMID:19650871. |
the endocannabinoid clearance inhibitor n-(4-hydrophenyl) arachidonoylamide (am404; 3 mg/kg) potentiated ethanol effects on 2-arachidonoylglycerol levels but did not alter ethanol-induced decreases in anandamide. |
2009-10-09 |
2023-08-12 |
rat |
| Lily Alvarez-Jaimes, David G Stouffer, Loren H Parson. Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. Journal of neurochemistry. vol 111. issue 1. 2009-10-09. PMID:19650871. |
then, we characterized the effect of ethanol challenge on nucleus accumbens endocannabinoid levels in rats previously maintained on an ethanol-containing liquid diet. |
2009-10-09 |
2023-08-12 |
rat |
| Alexander A Zoerner, Frank M Gutzki, Maria T Suchy, Bibiana Beckmann, Stefan Engeli, Jens Jordan, Dimitrios Tsika. Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 877. issue 26. 2009-09-28. PMID:19414283. |
targeted stable-isotope dilution gc-ms/ms analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. |
2009-09-28 |
2023-08-12 |
human |
| Alexander A Zoerner, Frank M Gutzki, Maria T Suchy, Bibiana Beckmann, Stefan Engeli, Jens Jordan, Dimitrios Tsika. Targeted stable-isotope dilution GC-MS/MS analysis of the endocannabinoid anandamide and other fatty acid ethanol amides in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 877. issue 26. 2009-09-28. PMID:19414283. |
anandamide (arachidonoyl ethanol amide, aea) is an endocannabinoid, acting on cb1 and cb2 receptors. |
2009-09-28 |
2023-08-12 |
human |
| Laura Orio, Scott Edwards, Olivier George, Loren H Parsons, George F Koo. A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 15. 2009-05-12. PMID:19369553. |
although emerging evidence implicates the endogenous cannabinoid system in aspects of opioid and ethanol addiction, a role of the endocannabinoid system in cocaine addiction remains widely inconclusive. |
2009-05-12 |
2023-08-12 |
human |
| b' Hanna Malinen, Petri Hyyti\\xc3\\xa. Ethanol self-administration is regulated by CB1 receptors in the nucleus accumbens and ventral tegmental area in alcohol-preferring AA rats. Alcoholism, clinical and experimental research. vol 32. issue 11. 2009-02-09. PMID:18782338.' |
endogenous cannabinoids and their receptors, cb1 receptors in particular, have been implicated in mediation of ethanol reinforcement. |
2009-02-09 |
2023-08-12 |
rat |
| Balapal S Basavarajappa, Ipe Ninan, Ottavio Aranci. Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons. Journal of neurochemistry. vol 107. issue 4. 2009-01-15. PMID:18796007. |
in this study, we show that ethanol enhances endocannabinoid (ec) levels in cultured hippocampal neurons, possibly through calcium pathways. |
2009-01-15 |
2023-08-12 |
Not clear |
| Rachel J Smith, Gary Aston-Jone. Noradrenergic transmission in the extended amygdala: role in increased drug-seeking and relapse during protracted drug abstinence. Brain structure & function. vol 213. issue 1-2. 2008-12-02. PMID:18651175. |
ne and crf transmission in the extended amygdala are also implicated in the increased anxiety that occurs during prolonged abstinence from chronic opiates, cocaine, ethanol, and cannabinoids. |
2008-12-02 |
2023-08-12 |
Not clear |
| D Parolaro, T Rubin. The role of the endogenous cannabinoid system in drug addiction. Drug news & perspectives. vol 21. issue 3. 2008-11-03. PMID:18560613. |
for a long time, dopamine has been consistently associated with the reinforcing effects of most drugs of abuse but, recently, pharmacological evidence points to the possibility that pharmacological management of the endocannabinoid system might not only block the direct reinforcing effect of cannabis, opioids, nicotine and ethanol, but also prevent the relapse to various drugs of abuse including opioids, cocaine, nicotine, alcohol and amphetamine. |
2008-11-03 |
2023-08-12 |
Not clear |
| Wanda Dyr, Janusz Ligieza, Wojciech Kostowsk. The effect of cannabinoid CB(1) receptor antagonist rimonabant (SR-141716) on ethanol drinking in high-preferring rats. Alcohol (Fayetteville, N.Y.). vol 42. issue 6. 2008-10-16. PMID:18504086. |
the effect of cannabinoid cb(1) receptor antagonist rimonabant (sr-141716) on ethanol drinking in high-preferring rats. |
2008-10-16 |
2023-08-12 |
rat |
| Wanda Dyr, Janusz Ligieza, Wojciech Kostowsk. The effect of cannabinoid CB(1) receptor antagonist rimonabant (SR-141716) on ethanol drinking in high-preferring rats. Alcohol (Fayetteville, N.Y.). vol 42. issue 6. 2008-10-16. PMID:18504086. |
the present study investigated the effect of the cannabinoid cb(1) receptor antagonist, rimonabant (sr-141716) on ethanol intake in selectively bred alcohol-preferring warsaw high-preferring rats. |
2008-10-16 |
2023-08-12 |
rat |