| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cheng Xiao, Jingli Zhang, Kresimir Krnjević, Jiang Hong Y. Effects of ethanol on midbrain neurons: role of opioid receptors. Alcoholism, clinical and experimental research. vol 31. issue 7. 2007-07-24. PMID:17577392. |
although ethanol addiction is believed to be mediated by the mesolimbic dopamine system, originating from the ventral tegmental area (vta), how acute ethanol increases the activity of vta dopaminergic (da) neurons remains unclear. |
2007-07-24 |
2023-08-12 |
Not clear |
| Christoph Fehr, Nina Hohmann, Gerhard Gründer, Thomas F Dielentheis, Hans-Georg Buchholz, Natalie Chechko, Igor Yakushev, Christian Landvogt, Peter Bartenstein, Reinhard Urban, Mathias Schreckenberge. Tiagabine does not attenuate alcohol-induced activation of the human reward system. Psychopharmacology. vol 191. issue 4. 2007-05-31. PMID:17265078. |
the rewarding effects of ethanol and other drugs of abuse are mediated by activation of the mesolimbic dopamine system. |
2007-05-31 |
2023-08-12 |
human |
| Anne M Landau, Edouard Kouassi, Rosmarie Siegrist-Johnstone, Julie Desbarat. Proteasome inhibitor model of Parkinson's disease in mice is confounded by neurotoxicity of the ethanol vehicle. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 3. 2007-05-01. PMID:17230468. |
ethanol significantly eclipses the effects of psi in the dopamine system, and therefore is a confounding vehicle for this model. |
2007-05-01 |
2023-08-12 |
mouse |
| Elin Löf, Mia Ericson, Rosita Stomberg, Bo Söderpal. Characterization of ethanol-induced dopamine elevation in the rat nucleus accumbens. European journal of pharmacology. vol 555. issue 2-3. 2007-04-04. PMID:17140561. |
it is unclear, however, where along the mesolimbic dopamine system this effect is initiated and why the ethanol-induced dopamine elevations are transient, returning to pre-drug baseline before brain and blood ethanol levels decline. |
2007-04-04 |
2023-08-12 |
rat |
| Anna Larsson, Lena Edström, Lennart Svensson, Bo Söderpalm, Jörgen A Enge. Voluntary ethanol intake increases extracellular acetylcholine levels in the ventral tegmental area in the rat. Alcohol and alcoholism (Oxford, Oxfordshire). vol 40. issue 5. 2006-01-11. PMID:16043436. |
the present experiments investigated a possible indirect effect of ethanol in stimulating the mesoaccumbal dopamine system. |
2006-01-11 |
2023-08-12 |
human |
| Julie Broadbent, Kathryn M Kampmueller, Sharon A Koons. Role of dopamine in behavioral sensitization to ethanol in DBA/2J mice. Alcohol (Fayetteville, N.Y.). vol 35. issue 2. 2005-10-04. PMID:15963427. |
the aim of the present study was to examine the role of different components of the dopamine system in sensitization to the locomotor stimulant effects of ethanol in dba/2j mice. |
2005-10-04 |
2023-08-12 |
mouse |
| Sonya K Sobrian, Barbara L Jones, Hutchinson James, Feremusu N Kamara, R Robert Holso. Prenatal ethanol preferentially enhances reactivity of the dopamine D1 but not D2 or D3 receptors in offspring. Neurotoxicology and teratology. vol 27. issue 1. 2005-05-02. PMID:15681123. |
reports of prenatal ethanol (etoh) effects on the dopamine system are inconsistent. |
2005-05-02 |
2023-08-12 |
human |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
the neurobiological processes by which ethanol seeking and consumption are established and maintained are thought to involve areas of the brain that mediate motivated behavior, such as the mesolimbic dopamine system. |
2005-01-07 |
2023-08-12 |
Not clear |
| Rueben A Gonzales, Martin O Job, William M Doyo. The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement. Pharmacology & therapeutics. vol 103. issue 2. 2005-01-07. PMID:15369680. |
behavioral experiments consistently show that pharmacological manipulations of the dopamine transmission in the nacc alter responding for ethanol, although ethanol reinforcement is maintained after lesions of the accumbal dopamine system. |
2005-01-07 |
2023-08-12 |
Not clear |
| Roberto I Melendez, Zachary A Rodd, William J McBride, James M Murph. Involvement of the mesopallidal dopamine system in ethanol reinforcement. Alcohol (Fayetteville, N.Y.). vol 32. issue 2. 2004-12-27. PMID:15163564. |
involvement of the mesopallidal dopamine system in ethanol reinforcement. |
2004-12-27 |
2023-08-12 |
rat |
| Roberto I Melendez, Zachary A Rodd, William J McBride, James M Murph. Involvement of the mesopallidal dopamine system in ethanol reinforcement. Alcohol (Fayetteville, N.Y.). vol 32. issue 2. 2004-12-27. PMID:15163564. |
these findings support the suggestion that dopaminergic activation in the ventral pallidum is involved in ethanol-seeking and ethanol-drinking behaviors and directly implicate the mesopallidal dopamine system in the reinforcing actions of ethanol. |
2004-12-27 |
2023-08-12 |
rat |
| A E Sahr, R J Thielen, L Lumeng, T-K Li, W J McBrid. Long-lasting alterations of the mesolimbic dopamine system after periadolescent ethanol drinking by alcohol-preferring rats. Alcoholism, clinical and experimental research. vol 28. issue 5. 2004-09-09. PMID:15166644. |
long-lasting alterations of the mesolimbic dopamine system after periadolescent ethanol drinking by alcohol-preferring rats. |
2004-09-09 |
2023-08-12 |
rat |
| Ana Stratone, Carmen Stratone, Fl Topolicean. [The neurotransmitters and alcohol dependence]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. vol 107. issue 2. 2004-07-13. PMID:14755936. |
thus pharmacological blockade of the endogenous opioid system by mu or delta opioid receptor antagonists prevents ethanol's activation of the dopamine system and reduces ethanol consumption. |
2004-07-13 |
2023-08-12 |
Not clear |
| Anna Larsson, Jörgen A Enge. Neurochemical and behavioral studies on ethanol and nicotine interactions. Neuroscience and biobehavioral reviews. vol 27. issue 8. 2004-04-19. PMID:15019421. |
the mesocorticolimbic dopamine system has been implicated in mediating some of the reinforcing effects of ethanol, however, the mechanism(s) of action remains to be elucidated; consideration as to ethanol's ability to interact with ligand-gated ion channels should be considered. |
2004-04-19 |
2023-08-12 |
Not clear |
| Anna Larsson, Jörgen A Enge. Neurochemical and behavioral studies on ethanol and nicotine interactions. Neuroscience and biobehavioral reviews. vol 27. issue 8. 2004-04-19. PMID:15019421. |
thus, it has been shown that the ethanol-induced stimulation of the mesolimbic dopamine system and of locomotor activity as well as ethanol intake and preference in rodents may involve central nicotinic acetylcholine receptors. |
2004-04-19 |
2023-08-12 |
Not clear |
| Anna Larsson, Jörgen A Enge. Neurochemical and behavioral studies on ethanol and nicotine interactions. Neuroscience and biobehavioral reviews. vol 27. issue 8. 2004-04-19. PMID:15019421. |
the possibility may thus be considered that ethanol activates the cholinergic afferents causing a release of acetylcholine in the ventral tegemental area leading to a stimulation of nachrs and thereby excite the mesocorticolimbic dopamine system. |
2004-04-19 |
2023-08-12 |
Not clear |
| Asa Rosin, Ian Kitchen, Jeanette Georgiev. Effects of single and dual administration of cocaine and ethanol on opioid and ORL1 receptor expression in rat CNS: an autoradiographic study. Brain research. vol 978. issue 1-2. 2003-09-08. PMID:12834892. |
both cocaine and ethanol increase the extracellular dopamine concentration in the nucleus accumbens, a terminal region in the mesolimbic dopamine pathway. |
2003-09-08 |
2023-08-12 |
human |
| Asa Rosin, Ian Kitchen, Jeanette Georgiev. Effects of single and dual administration of cocaine and ethanol on opioid and ORL1 receptor expression in rat CNS: an autoradiographic study. Brain research. vol 978. issue 1-2. 2003-09-08. PMID:12834892. |
in addition, both cocaine and ethanol affect the endogenous opioid system, which in turn alters the activity of the mesolimbic dopamine pathway. |
2003-09-08 |
2023-08-12 |
human |
| Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
the mesoaccumbens dopamine system has been hypothesized to be a common neural substrate mediating the actions of various drugs of abuse, including ethanol. |
2003-06-11 |
2023-08-12 |
rat |
| Roberto I Melendez, Zachary A Rodd-Henricks, William J McBride, James M Murph. Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 5. 2003-06-11. PMID:12637946. |
the data suggest that the mesopallidal, mesoaccumbens, and nigrostriatal dopamine systems are more sensitive to the effects of ethanol than the nigropallidal dopamine system. |
2003-06-11 |
2023-08-12 |
rat |