| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sara González, Maria Grazia Cascio, Javier Fernández-Ruiz, Filomena Fezza, Vincenzo Di Marzo, José A Ramo. Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine. Brain research. vol 954. issue 1. 2003-01-24. PMID:12393235. |
in the present study, we have extended this objective by examining changes in the brain contents of arachidonoylethanolamide (aea) and 2-arachidonoyl-glycerol (2-ag), the endogenous ligands for cannabinoid receptors, in animals chronically exposed to cocaine, nicotine or ethanol. |
2003-01-24 |
2023-08-12 |
rat |
| Harald Schütz, Jan Christoph Gotta, Freidoon Erdmann, Manfred Risse, Günter Weile. Simultaneous screening and detection of drugs in small blood samples and bloodstains. Forensic science international. vol 126. issue 3. 2002-11-07. PMID:12062939. |
the detection limits are in the order of 1.62-4.10 ng/50 microl spot (amphetamines), 0.15-0.82 ng/50 microl spot (cannabinoids), 1.67-4.70 ng/50 microl spot (cocaine and derivatives) and 4.53-4.91 ng/50 microl spot (opiates) and the correlation factors are between 0.9957 and 0.9999. |
2002-11-07 |
2023-08-12 |
Not clear |
| Mario Cassani, Lucia Giuliani, Maurizio Amigoni, Antonietta Buratta, Alessandro Marocch. Experience with external quality assessment of drugs of abuse testing in the Lombardy Region in Italy. Clinical chemistry and laboratory medicine. vol 40. issue 2. 2002-10-02. PMID:11939489. |
both types of samples could contain the following substances/classes of substances: opiates, cocaine, cannabinoids, methadone, buprenorphine, benzodiazepines, barbiturates. |
2002-10-02 |
2023-08-12 |
Not clear |
| Manfred R Moeller, Thomas Kraeme. Drugs of abuse monitoring in blood for control of driving under the influence of drugs. Therapeutic drug monitoring. vol 24. issue 2. 2002-06-06. PMID:11897967. |
this review describes procedures for detection of the following drugs of abuse in whole blood, plasma, and serum: amphetamine, methamphetamine, 3,4-methylenedioxy methamphetamine (mdma), n-ethyl-3, 4-methylenedioxyamphetamine (mdea), 3,4-methylenedioxyamphetamine (mda), cannabinoids (delta-9-tetrahydrocannabinol [thc], 11-hydroxy-delta-9-thc, 11-nor-9-carboxy-delta-9-thc), cocaine, benzoylecgonine, ecgonine methyl ester, cocaethylene, the opiates (heroin, 6-monoacetylmorphine, morphine, or codeine), and methadone as well as gamma-hydroxybutyric acid (ghb), lysergic acid diethylamide (lsd), phencyclidine (pcp), and psilocybin/psilocin. |
2002-06-06 |
2023-08-12 |
Not clear |
| L Fattore, M C Puddu, S Picciau, A Cappai, W Fratta, G P Serra, S Spig. Astroglial in vivo response to cocaine in mouse dentate gyrus: a quantitative and qualitative analysis by confocal microscopy. Neuroscience. vol 110. issue 1. 2002-05-23. PMID:11882367. |
quantitative changes in the expression of glial fibrillary acidic protein (gfap), a cytoskeletal intermediate filament protein exclusively expressed in astrocytes (bignami et al, 1972), have been observed after administration of alcohol (framke, 1995), morphine (beitner-johnson et al., 1993), amphetamine and its derivates (aguirre et al., 1999), cannabinoids (suarez et al., 2000), nicotine (janson and moller, 1993), caffeine (marret et al., 1993) and prenatal exposure to cocaine (clarke et al., 1996; nassogne et al., 1998). |
2002-05-23 |
2023-08-12 |
mouse |
| Gunnel Ceder, Alan Wayne Jone. Concentrations of unconjugated morphine, codeine and 6-acetylmorphine in urine specimens from suspected drugged drivers. Journal of forensic sciences. vol 47. issue 2. 2002-05-20. PMID:11908609. |
after an initial screening analysis by immunoassay for 5-classes of abused drugs (opiates, cannabinoids, amphetamine analogs, cocaine metabolite and benzodiazepines), all positive specimens were verified by more specific methods. |
2002-05-20 |
2023-08-12 |
Not clear |
| Sara Gonzalez, Javier Fernandez-Ruiz, Valentina Sparpaglione, Daniela Parolaro, Jose A Ramo. Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levels. Drug and alcohol dependence. vol 66. issue 1. 2002-05-16. PMID:11850139. |
chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid cb(1) receptor binding and mrna levels. |
2002-05-16 |
2023-08-12 |
rat |
| Sara Gonzalez, Javier Fernandez-Ruiz, Valentina Sparpaglione, Daniela Parolaro, Jose A Ramo. Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levels. Drug and alcohol dependence. vol 66. issue 1. 2002-05-16. PMID:11850139. |
however, there are not many studies that compare the changes in endocannabinoid ligands and/or receptors in brain regions (particularly in those areas related to reinforcement processes) during dependence to opiates, cocaine or alcohol. |
2002-05-16 |
2023-08-12 |
rat |
| Sara Gonzalez, Javier Fernandez-Ruiz, Valentina Sparpaglione, Daniela Parolaro, Jose A Ramo. Chronic exposure to morphine, cocaine or ethanol in rats produced different effects in brain cannabinoid CB(1) receptor binding and mRNA levels. Drug and alcohol dependence. vol 66. issue 1. 2002-05-16. PMID:11850139. |
the results indicate that mechanisms of dependence for alcohol, cocaine and morphine are different in terms of their impact on the endocannabinoid system. |
2002-05-16 |
2023-08-12 |
rat |
| Albert D Fraser, Jiri Zamecni. Substance abuse monitoring by the Correctional Service of Canada. Therapeutic drug monitoring. vol 24. issue 1. 2002-04-23. PMID:11805743. |
urine specimens were tested for drugs of abuse and prescription drugs including amphetamines, cannabinoids, cocaine metabolite, opiates, phencyclidine, benzodiazepines, methyl phenidate, meperidine, pentazocine and fluoxetine by immunoassay screening followed by gc-ms confirmation. |
2002-04-23 |
2023-08-12 |
human |
| Albert D Fraser, Jiri Zamecni. Substance abuse monitoring by the Correctional Service of Canada. Therapeutic drug monitoring. vol 24. issue 1. 2002-04-23. PMID:11805743. |
in the community setting 28,076 normally concentrated (nondilute) specimens were tested (9.6% were positive for cannabinoids and 3.3% positive for cocaine metabolite). |
2002-04-23 |
2023-08-12 |
human |
| Albert D Fraser, Jiri Zamecni. Substance abuse monitoring by the Correctional Service of Canada. Therapeutic drug monitoring. vol 24. issue 1. 2002-04-23. PMID:11805743. |
in the 1,270 dilute specimens collected from conditional release offenders in 2000, 12.8% were positive for cannabinoids and 10.6% were positive for cocaine metabolite. |
2002-04-23 |
2023-08-12 |
human |
| T Hayase, Y Yamamoto, K Yamamot. Protective effects of cannabinoid receptor agonists against cocaine and other convulsant-induced toxic behavioural symptoms. The Journal of pharmacy and pharmacology. vol 53. issue 11. 2002-04-05. PMID:11732755. |
the cannabinoid receptor agonists cp 55940 ((-)-cis-3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)-cyclohexanol) and win 55212-2 ((r)-(+)-[2,3-dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone), and the endogenous cannabinoid anandamide were co-administered intraperitoneally with cocaine (75 mg kg(-1)) or other convulsants such as bicuculline, methyl 6,7-dimethoxy-4-ethyl-beta-carboline-carboxylate (dmcm), l-glutamic acid and n-methyl-d-aspartate (nmda). |
2002-04-05 |
2023-08-12 |
mouse |
| R Boskovic, J Klein, C Woodland, T Karaskov, G Kore. The role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study. Canadian journal of physiology and pharmacology. vol 79. issue 11. 2002-03-22. PMID:11760096. |
the role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study. |
2002-03-22 |
2023-08-12 |
Not clear |
| R Boskovic, J Klein, C Woodland, T Karaskov, G Kore. The role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study. Canadian journal of physiology and pharmacology. vol 79. issue 11. 2002-03-22. PMID:11760096. |
there is wide variability in the reported adverse fetal effects of cocaine and cannabinoids. |
2002-03-22 |
2023-08-12 |
Not clear |
| R Boskovic, J Klein, C Woodland, T Karaskov, G Kore. The role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study. Canadian journal of physiology and pharmacology. vol 79. issue 11. 2002-03-22. PMID:11760096. |
out of 12 pairs, 5 had negative levels in both twins, and seven pairs of twins had chemical evidence of fetal exposure to cocaine (n = 5) or cannabinoids (n = 2). |
2002-03-22 |
2023-08-12 |
Not clear |
| R Boskovic, J Klein, C Woodland, T Karaskov, G Kore. The role of the placenta in variability of fetal exposure to cocaine and cannabinoids: a twin study. Canadian journal of physiology and pharmacology. vol 79. issue 11. 2002-03-22. PMID:11760096. |
in contrast, the six dizygotic pairs had large disparities in either cocaine or cannabinoid concentrations. |
2002-03-22 |
2023-08-12 |
Not clear |
| T Hayase, Y Yamamoto, K Yamamot. Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence. vol 36. issue 6. 2002-03-08. PMID:11828716. |
the effects of the endogenous cannabinoid (cb) anandamide (aea) and its analogs on cocaine (coca)-induced toxic symptoms such as lethality, convulsive seizures and hyperactivity were examined in mice. |
2002-03-08 |
2023-08-12 |
mouse |
| A Leino, J Saarimies, M Grönholm, P Lillsund. Comparison of eight commercial on-site screening devices for drugs-of-abuse testing. Scandinavian journal of clinical and laboratory investigation. vol 61. issue 4. 2001-12-12. PMID:11465347. |
eight commercially available on-site drugs-of-abuse testing devices for detecting cannabinoids (thc-cooh), opiates (opi), cocaine (coc), amphetamines (amp), metamphetamines (met) and benzodiazepines (bzo) were evaluated. |
2001-12-12 |
2023-08-12 |
Not clear |
| A D Frase. A 6-year experience with urine drug testing by family service agencies in Nova Scotia, Canada. Forensic science international. vol 121. issue 3. 2001-11-01. PMID:11566417. |
each urine specimen was screened for cannabinoids, cocaine metabolite, opiates, amphetamines and benzodiazepines, ethyl alcohol and creatinine. |
2001-11-01 |
2023-08-12 |
Not clear |