| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonathon C Arnol. The role of endocannabinoid transmission in cocaine addiction. Pharmacology, biochemistry, and behavior. vol 81. issue 2. 2005-09-08. PMID:15925401. |
while animal research suggests cannabis use may precipitate cocaine relapse, cross-sensitization between cannabinoids and cocaine has not been demonstrated and cb1 receptors do not mediate behavioral sensitization to cocaine. |
2005-09-08 |
2023-08-12 |
human |
| Jonathon C Arnol. The role of endocannabinoid transmission in cocaine addiction. Pharmacology, biochemistry, and behavior. vol 81. issue 2. 2005-09-08. PMID:15925401. |
the effect of acute or chronic cocaine on endocannabinoid transmission in reward-related areas of the brain is relatively under-researched. |
2005-09-08 |
2023-08-12 |
human |
| Jonathon C Arnol. The role of endocannabinoid transmission in cocaine addiction. Pharmacology, biochemistry, and behavior. vol 81. issue 2. 2005-09-08. PMID:15925401. |
this review highlights research indicating that the endocannabinoid system may subserve certain aspects of cocaine addiction and suggests avenues for future investigation. |
2005-09-08 |
2023-08-12 |
human |
| Joe Clarke, John F Wilso. Proficiency testing (external quality assessment) of drug detection in oral fluid. Forensic science international. vol 150. issue 2-3. 2005-09-08. PMID:15944056. |
the sensitivity for overall "present"/"not found" reports calculated as true positives/(true positives+false negatives) were for the amphetamine specific assay 50%, methyl-amphetamines 93%, barbiturates 64%, cannabinoids 73%, cocaine and metabolites 100%, benzodiazepines 69%, methadone 95%, opiates 79% (opiates excluding oxycodone 93%), phencyclidine 93% and human gamma-globulin 97%. |
2005-09-08 |
2023-08-12 |
human |
| I M Bernhoft, A Steentoft, S S Johansen, N A Klitgaard, L B Larsen, L B Hanse. Drugs in injured drivers in Denmark. Forensic science international. vol 150. issue 2-3. 2005-09-08. PMID:15944058. |
mdma (ecstasy), cannabinoids and metabolites, cocaine and metabolites and benzodiazepines. |
2005-09-08 |
2023-08-12 |
Not clear |
| Stefan W Toennes, Gerold F Kauert, Stefan Steinmeyer, Manfred R Moelle. Driving under the influence of drugs -- evaluation of analytical data of drugs in oral fluid, serum and urine, and correlation with impairment symptoms. Forensic science international. vol 152. issue 2-3. 2005-09-08. PMID:15978340. |
analysis for cannabinoids, amphetamine and its derivatives, opiates and cocaine was performed in urine using the mahsan kombi/doa4-test, in serum using immunoassay and gas chromatography-mass spectrometry (gc-ms) confirmation and in oral fluid by gc-ms. police and medical officer observations of impairment symptoms were rated and evaluated using a threshold value for the classification of driving inability. |
2005-09-08 |
2023-08-12 |
Not clear |
| Dennis J Crouch, J M Walsh, Ron Flegel, Leo Cangianelli, Jakub Baudys, Randy Atkin. An evaluation of selected oral fluid point-of-collection drug-testing devices. Journal of analytical toxicology. vol 29. issue 4. 2005-08-08. PMID:15975256. |
in the study reported here, two more devices, oratect(r) (branan) and uplink(r) (orasure), were evaluated for their ability to detect amphetamines, cocaine, opiates, and cannabinoids. |
2005-08-08 |
2023-08-12 |
Not clear |
| Dennis J Crouch, J M Walsh, Ron Flegel, Leo Cangianelli, Jakub Baudys, Randy Atkin. An evaluation of selected oral fluid point-of-collection drug-testing devices. Journal of analytical toxicology. vol 29. issue 4. 2005-08-08. PMID:15975256. |
an additional device, drugwipe (securtec), was evaluated for the detection of cocaine and cannabinoids. |
2005-08-08 |
2023-08-12 |
Not clear |
| b' Sabina Strano-Rossi, Francesco Molaioni, Francesca Rossi, Francesco Botr\\xc3\\xa. Rapid screening of drugs of abuse and their metabolites by gas chromatography/mass spectrometry: application to urinalysis. Rapid communications in mass spectrometry : RCM. vol 19. issue 11. 2005-07-22. PMID:15880665.' |
synthetic stimulants, opiates, cocaine metabolites, cannabinoids--and specifically the acid metabolite of tetrahydrocannabinol (thc-cooh)--can be simultaneously extracted by a single liquid/liquid separation step, at alkaline ph, and assayed as trimethylsilyl derivatives by gc/ms in sim (selected ion monitoring) mode. |
2005-07-22 |
2023-08-12 |
human |
| B E Smink, B Ruiter, K J Lusthof, J J de Gier, D R A Uges, A C G Egbert. Drug use and the severity of a traffic accident. Accident; analysis and prevention. vol 37. issue 3. 2005-07-21. PMID:15784196. |
all the blood samples obtained after the accident were screened for the presence of alcohol, illicit drugs (opiates, amphetamines and amphetamine-like substances, cocaine and metabolites, methadone, cannabinoids) and medicinal drugs (benzodiazepines, barbiturates and tricyclic antidepressants). |
2005-07-21 |
2023-08-12 |
Not clear |
| B E Smink, B Ruiter, K J Lusthof, J J de Gier, D R A Uges, A C G Egbert. Drug use and the severity of a traffic accident. Accident; analysis and prevention. vol 37. issue 3. 2005-07-21. PMID:15784196. |
the most frequently detected drugs were cannabinoids, benzodiazepines and cocaine. |
2005-07-21 |
2023-08-12 |
Not clear |
| Heidi M B Lesscher, Emily Hoogveld, J Peter H Burbach, Jan M van Ree, Mirjam A F M Gerrit. Endogenous cannabinoids are not involved in cocaine reinforcement and development of cocaine-induced behavioural sensitization. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 1. 2005-03-29. PMID:15572271. |
endogenous cannabinoids are not involved in cocaine reinforcement and development of cocaine-induced behavioural sensitization. |
2005-03-29 |
2023-08-12 |
Not clear |
| Heidi M B Lesscher, Emily Hoogveld, J Peter H Burbach, Jan M van Ree, Mirjam A F M Gerrit. Endogenous cannabinoids are not involved in cocaine reinforcement and development of cocaine-induced behavioural sensitization. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 15. issue 1. 2005-03-29. PMID:15572271. |
the cannabinoid cb1 receptors have recently been implicated in rewarding aspects of not only the cannabinoid drug delta9-tetrahydrocannabinol (delta9-thc), but also of other drugs of abuse, including cocaine. |
2005-03-29 |
2023-08-12 |
Not clear |
| Teemu Gunnar, Sirpa Mykkänen, Kari Ariniemi, Pirjo Lillsund. Validated semiquantitative/quantitative screening of 51 drugs in whole blood as silylated derivatives by gas chromatography-selected ion monitoring mass spectrometry and gas chromatography electron capture detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 806. issue 2. 2005-02-24. PMID:15171931. |
benzodiazepines (12), cannabinoids (3), opioids (8), cocaine, antidepressants (13), antipsychotics (5) and antiepileptics (2) as well as zolpidem, zaleplon, zopiclone, meprobamate, carisoprodol, tizanidine and orphenadrine and internal standard flurazepam, were isolated by high-yield liquid-liquid extraction (lle). |
2005-02-24 |
2023-08-12 |
Not clear |
| Toru Kobayashi, Kazuo Washiyama, Kazutaka Iked. Modulators of G protein-activated inwardly rectifying K+ channels: potentially therapeutic agents for addictive drug users. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542767. |
it has been shown that the function of girk channels is involved in seizure susceptibility, antinociception by opioids, cannabinoids, or ethanol, and cocaine reinforcement in studies using girk knockout mice and weaver mutant mice that have mutant girk2 channels insensitive to g proteins and ethanol. |
2005-02-18 |
2023-08-12 |
mouse |
| Toru Kobayashi, Kazuo Washiyama, Kazutaka Iked. Modulators of G protein-activated inwardly rectifying K+ channels: potentially therapeutic agents for addictive drug users. Annals of the New York Academy of Sciences. vol 1025. 2005-02-18. PMID:15542767. |
therefore, girk channel modulators might be potential agents for the treatment of users of addictive drugs, such as cocaine, opioids, cannabinoids, and ethanol, as well as for the treatment of epilepsy and pain. |
2005-02-18 |
2023-08-12 |
mouse |
| Eric S Lavins, Bethany D Lavins, Amanda J Jenkin. Cannabis (marijuana) contamination of United States and foreign paper currency. Journal of analytical toxicology. vol 28. issue 6. 2005-02-04. PMID:15516293. |
as is the case with cocaine, differentiating "background levels" of the various cannabinoid constituents of cannabis sativa l., namely, delta(9)-tetrahydrocannabinol (thc), cannabinol (cbn), and cannabidiol (cbd) contaminating currency found in the general circulation from currency associated with illegal drug activity is imperative if a legal nexus is to be established with the latter. |
2005-02-04 |
2023-08-12 |
Not clear |
| Christian Giroud, Katarzyna Michaud, Frank Sporkert, Chin Eap, Marc Augsburger, Pascal Cardinal, Patrice Mangi. A fatal overdose of cocaine associated with coingestion of marijuana, buprenorphine, and fluoxetine. Body fluid and tissue distribution of cocaine and its metabolites determined by hydrophilic interaction chromatography-mass spectrometry(HILIC-MS). Journal of analytical toxicology. vol 28. issue 6. 2005-02-04. PMID:15516297. |
likewise, combination of cannabinoids and cocaine might have increase detrimental cardiovascular effects. |
2005-02-04 |
2023-08-12 |
Not clear |
| Christian Giroud, Katarzyna Michaud, Frank Sporkert, Chin Eap, Marc Augsburger, Pascal Cardinal, Patrice Mangi. A fatal overdose of cocaine associated with coingestion of marijuana, buprenorphine, and fluoxetine. Body fluid and tissue distribution of cocaine and its metabolites determined by hydrophilic interaction chromatography-mass spectrometry(HILIC-MS). Journal of analytical toxicology. vol 28. issue 6. 2005-02-04. PMID:15516297. |
altogether, these results indicate a lethal cocaine overdose with a minor contribution of fluoxetine and cannabinoids. |
2005-02-04 |
2023-08-12 |
Not clear |
| Peer K Lilleng, Lars Ivar Mehlum, Liliana Bachs, Inge Moril. Deaths after intravenous misuse of transdermal fentanyl. Journal of forensic sciences. vol 49. issue 6. 2005-01-21. PMID:15568716. |
post-mortem femoral blood was screened for amphetamines, cannabinoids, cocaine, and opioids with immunological methods (emit ii) and further with headspace gas chromatography for alcohol and with liquid chromatography mass spectrometry (lc-ms) for different drugs, including fentanyl. |
2005-01-21 |
2023-08-12 |
Not clear |